New biomarkers of acute kidney injury.

Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol (2010) 3.03

Urinary biomarkers in the early detection of acute kidney injury after cardiac surgery. Clin J Am Soc Nephrol (2009) 2.57

Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med (2011) 2.55

Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: a prospective multicenter study. Crit Care Med (2011) 2.41

Biomarker discovery and development in pediatric critical care medicine. Pediatr Crit Care Med (2011) 2.08

Serum and urine cystatin C are poor biomarkers for acute kidney injury and renal replacement therapy. Intensive Care Med (2010) 2.01

Biomarkers for the early detection of acute kidney injury. Curr Opin Pediatr (2011) 2.01

Biomarkers predict progression of acute kidney injury after cardiac surgery. J Am Soc Nephrol (2012) 2.00

Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury. Nat Biotechnol (2010) 2.00

Neutrophil gelatinase-associated lipocalin: a promising biomarker for human acute kidney injury. Biomark Med (2010) 1.90

Neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery: the effect of baseline renal function on diagnostic performance. Clin J Am Soc Nephrol (2010) 1.73

Pathophysiology of acute kidney injury. Compr Physiol (2012) 1.56

Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit. Crit Care (2010) 1.50

Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants. Pediatr Res (2011) 1.30

Cystatin C as a marker of acute kidney injury in the emergency department. Clin J Am Soc Nephrol (2010) 1.25

Analysis of a urinary biomarker panel for incident kidney disease and clinical outcomes. J Am Soc Nephrol (2013) 1.08

Biomarkers for early diagnosis of AKI in the ICU: ready for prime time use at the bedside? Ann Intensive Care (2012) 1.05

Acute kidney injury biomarkers for patients in a coronary care unit: a prospective cohort study. PLoS One (2012) 1.02

New biomarkers of acute kidney injury and the cardio-renal syndrome. Korean J Lab Med (2011) 0.99

Marking renal injury: can we move beyond serum creatinine? Transl Res (2012) 0.98

Risk factors and outcomes stratified by severity of acute kidney injury in malaria. PLoS One (2014) 0.95

Intra-amniotic infection upregulates neutrophil gelatinase-associated lipocalin (NGAL) expression at the maternal-fetal interface at term: implications for infection-related preterm birth. Reprod Sci (2011) 0.92

Adjudication of etiology of acute kidney injury: experience from the TRIBE-AKI multi-center study. BMC Nephrol (2014) 0.89

Urinary cystatin C and acute kidney injury after cardiac surgery. Am J Kidney Dis (2013) 0.89

Urinary biomarkers and renal near-infrared spectroscopy predict intensive care unit outcomes after cardiac surgery in infants younger than 6 months of age. J Thorac Cardiovasc Surg (2013) 0.86

Fluid overload in AKI: epiphenomenon or putative effect on mortality? Curr Opin Crit Care (2012) 0.84

Cardiorenal syndromes. World J Cardiol (2011) 0.83

Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis. Antioxid Redox Signal (2015) 0.83

Enabling innovative translational research in acute kidney injury. Clin Transl Sci (2011) 0.81

Urinary biomarkers of acute kidney injury in patients with liver cirrhosis. ISRN Nephrol (2014) 0.81

Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat. Biometals (2015) 0.81

A pilot study of urinary fibroblast growth factor-2 and epithelial growth factor as potential biomarkers of acute kidney injury in critically ill children. Pediatr Nephrol (2013) 0.80

A polymeric nanomedicine diminishes inflammatory events in renal tubular cells. PLoS One (2013) 0.80

Intraoperative hyperglycemia augments ischemia reperfusion injury in renal transplantation: a prospective study. J Transplant (2011) 0.80

Serial non-invasive monitoring of renal disease following immune-mediated injury using near-infrared optical imaging. PLoS One (2012) 0.79

Acute kidney injury in the perioperative period and in intensive care units (excluding renal replacement therapies). Ann Intensive Care (2016) 0.78

Intrarenal resistance index for the assessment of acute renal injury in a rat liver transplantation model. BMC Nephrol (2013) 0.78

Use of urine biomarker-derived clusters to predict the risk of chronic kidney disease and all-cause mortality in HIV-infected women. Nephrol Dial Transplant (2016) 0.77

Retracted Urinary biomarkers of acute kidney injury in patients with liver cirrhosis. Med Arch (2014) 0.76

Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: a multicenter prospective observational study. PLoS One (2015) 0.76

Role of biomarkers of nephrotoxic acute kidney injury in deliberate poisoning and envenomation in less developed countries. Br J Clin Pharmacol (2015) 0.76

Performance of urinary and gene expression biomarkers in detecting the nephrotoxic effects of melamine and cyanuric acid following diverse scenarios of co-exposure. Food Chem Toxicol (2012) 0.75

Risk prediction of acute kidney injury in cardiac surgery and prevention using aminophylline. Indian J Nephrol (2012) 0.75

Effects of Sugammadex and Neostigmine on Renal Biomarkers. Med Sci Monit (2016) 0.75

Interdisciplinary Systems-Based Intervention to Improve IV Hydration during Parenteral Administration of Acyclovir. Can J Hosp Pharm (2016) 0.75

Cystatin C at Admission in the Intensive Care Unit Predicts Mortality among Elderly Patients. ISRN Nephrol (2013) 0.75

Renal injury in neonates: use of "omics" for developing precision medicine in neonatology. Pediatr Res (2016) 0.75

Sepsis and Acute Kidney Injury. Turk J Anaesthesiol Reanim (2014) 0.75

Circulating levels of neutrophil gelatinase-associated lipocalin (NGAL) correlate with the presence and severity of preeclampsia. Reprod Sci (2013) 0.75

Identification of an Adamantyl Azaquinolone JNK Selective Inhibitor. ACS Med Chem Lett (2012) 0.75

Evaluation of clinically available renal biomarkers in critically ill adults: a prospective multicenter observational study. Crit Care (2017) 0.75

Serum Cystatin C for the Diagnosis of Acute Kidney Injury in Patients Admitted in the Emergency Department. Dis Markers (2015) 0.75

Decreased renal function in hypertensive emergencies. J Hum Hypertens (2014) 0.75

Kidney Injury and Repair Biomarkers in Marathon Runners. Am J Kidney Dis (2017) 0.75

Associations between Deceased-Donor Urine MCP-1 and Kidney Transplant Outcomes. KI Rep (2017) 0.75

Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet (2005) 13.77

Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol (2003) 9.08

Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis (2009) 6.99

Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Intern Med (2008) 5.89

Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest (2005) 5.51

Dual action of neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol (2007) 4.99

The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies. J Am Coll Cardiol (2011) 4.57

Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study. Clin J Am Soc Nephrol (2008) 4.56

Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery--a prospective cohort study. Crit Care Med (2009) 4.30

Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery. J Am Soc Nephrol (2011) 3.53

Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care (2007) 3.29

The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat Med (2011) 3.20

Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care (2007) 3.19

Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypass. J Am Coll Cardiol (2011) 3.17

Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery. Kidney Int (2008) 3.12

Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney Int (2011) 3.05

Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol (2010) 3.03

NGAL is an early predictive biomarker of contrast-induced nephropathy in children. Pediatr Nephrol (2007) 2.99

Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study. J Am Coll Cardiol (2012) 2.97

Amelioration of ischemic acute renal injury by neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol (2004) 2.96

Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus non-septic acute kidney injury in critical illness. Intensive Care Med (2009) 2.94

Neutrophil gelatinase-associated lipocalin: a novel early urinary biomarker for cisplatin nephrotoxicity. Am J Nephrol (2004) 2.91

Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery. J Am Soc Nephrol (2011) 2.90

The predictive performance of plasma neutrophil gelatinase-associated lipocalin (NGAL) increases with grade of acute kidney injury. Nephrol Dial Transplant (2009) 2.73

Differential gene expression following early renal ischemia/reperfusion. Kidney Int (2003) 2.60

Kidney NGAL is a novel early marker of acute injury following transplantation. Pediatr Nephrol (2006) 2.48

Sodium bicarbonate to prevent increases in serum creatinine after cardiac surgery: a pilot double-blind, randomized controlled trial. Crit Care Med (2009) 2.45

IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation. J Am Soc Nephrol (2009) 2.43

Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: a prospective multicenter study. Crit Care Med (2011) 2.41

Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia. Curr Opin Nephrol Hypertens (2006) 2.34

Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Crit Care Med (2008) 2.32

Urinary neutrophil gelatinase-associated lipocalin as a biomarker of nephritis in childhood-onset systemic lupus erythematosus. Arthritis Rheum (2006) 2.27

NGAL distinguishes steroid sensitivity in idiopathic nephrotic syndrome. Pediatr Nephrol (2011) 2.19

Novel biomarkers early predict the severity of acute kidney injury after cardiac surgery in adults. Ann Thorac Surg (2009) 2.19

Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease. Pediatr Nephrol (2006) 2.18

Urinary neutrophil gelatinase-associated lipocalcin in D+HUS: a novel marker of renal injury. Pediatr Nephrol (2006) 2.09

Acute kidney injury in childhood: should we be worried about progression to CKD? Pediatr Nephrol (2010) 2.00

Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin J Am Soc Nephrol (2012) 1.90

Early postoperative serum cystatin C predicts severe acute kidney injury following pediatric cardiac surgery. Kidney Int (2011) 1.88

Tolerance of the human kidney to isolated controlled ischemia. J Am Soc Nephrol (2013) 1.82

Biomarkers in acute and chronic kidney disease. Curr Opin Nephrol Hypertens (2008) 1.81

Biomarkers for the early detection of acute kidney injury. Pediatr Nephrol (2007) 1.69

Neutrophil gelatinase-associated lipocalin concentrations predict development of acute kidney injury in neonates and children after cardiopulmonary bypass. J Pediatr (2011) 1.66

The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods. BMC Nephrol (2010) 1.63

Serum interleukin-6 and interleukin-8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: a case-control study. Crit Care (2009) 1.61

Cisplatin nephrotoxicity: molecular mechanisms. Cancer Ther (2003) 1.61

Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney Int (2012) 1.55

Cisplatin induces apoptosis in LLC-PK1 cells via activation of mitochondrial pathways. J Am Soc Nephrol (2002) 1.51

Induction of proapoptotic Daxx following ischemic acute kidney injury. Kidney Int (2008) 1.49

Performance of kidney injury molecule-1 and liver fatty acid-binding protein and combined biomarkers of AKI after cardiac surgery. Clin J Am Soc Nephrol (2013) 1.48

Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status. Ann Clin Biochem (2014) 1.47

Neutrophil gelatinase-associated lipocalin as a biomarker of disease activity in pediatric lupus nephritis. Pediatr Nephrol (2008) 1.42

Tubular proteinuria in acute kidney injury: a critical evaluation of current status and future promise. Ann Clin Biochem (2010) 1.36

Neutrophil gelatinase-associated lipocalin is a predictor of the course of global and renal childhood-onset systemic lupus erythematosus disease activity. Arthritis Rheum (2009) 1.36

Neutrophil gelatinase-associated lipocalin--an emerging troponin for kidney injury. Nephrol Dial Transplant (2008) 1.35

Activation of mitochondrial apoptotic pathways in human renal allografts after ischemiareperfusion injury. Transplantation (2003) 1.35

Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury. J Am Soc Nephrol (2011) 1.35

Urinary NGAL marks cystic disease in HIV-associated nephropathy. J Am Soc Nephrol (2009) 1.34

Association of noninvasively measured renal protein biomarkers with histologic features of lupus nephritis. Arthritis Rheum (2012) 1.32

Plasma NGAL for the diagnosis of AKI in patients admitted from the emergency department setting. Clin J Am Soc Nephrol (2013) 1.31

Urinary NGAL in premature infants. Pediatr Res (2008) 1.30

Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants. Pediatr Res (2011) 1.30

NGAL (Lcn2) monomer is associated with tubulointerstitial damage in chronic kidney disease. Kidney Int (2012) 1.30

Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants. J Pediatr (2011) 1.28

A framework and key research questions in AKI diagnosis and staging in different environments. Clin J Am Soc Nephrol (2008) 1.27

Cystatin C as a marker of acute kidney injury in the emergency department. Clin J Am Soc Nephrol (2010) 1.25

Initial validation of a novel protein biomarker panel for active pediatric lupus nephritis. Pediatr Res (2009) 1.24

Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli. Nephron Exp Nephrol (2007) 1.24

Serum cystatin C is an early predictive biomarker of acute kidney injury after pediatric cardiopulmonary bypass. Clin J Am Soc Nephrol (2010) 1.22

Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials. Clin J Am Soc Nephrol (2012) 1.20

NGAL in acute kidney injury: from serendipity to utility. Am J Kidney Dis (2008) 1.20

Urinary netrin-1 is an early predictive biomarker of acute kidney injury after cardiac surgery. Clin J Am Soc Nephrol (2009) 1.20

The association of albumin/creatinine ratio with postoperative AKI in children undergoing cardiac surgery. Clin J Am Soc Nephrol (2012) 1.20

Presurgical serum cystatin C and risk of acute kidney injury after cardiac surgery. Am J Kidney Dis (2011) 1.17

Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray. Crit Care (2011) 1.16

Improving outcomes from acute kidney injury: report of an initiative. Pediatr Nephrol (2007) 1.15

An update and review of acute kidney injury in pediatrics. Pediatr Crit Care Med (2011) 1.15

Urinary aprotinin as a predictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy. Pediatr Nephrol (2008) 1.14

Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings. Clin J Am Soc Nephrol (2012) 1.13

Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells. J Am Soc Nephrol (2007) 1.13

Pediatric reference ranges for acute kidney injury biomarkers. Pediatr Nephrol (2014) 1.10

Semaphorin 3A is a new early diagnostic biomarker of experimental and pediatric acute kidney injury. PLoS One (2013) 1.10

Albuminuria increases cystatin C excretion: implications for urinary biomarkers. Nephrol Dial Transplant (2011) 1.08

Urinary biomarkers to detect acute kidney injury in the pediatric emergency center. Pediatr Nephrol (2010) 1.08

A prospective evaluation of urine microscopy in septic and non-septic acute kidney injury. Nephrol Dial Transplant (2011) 1.07

Induction of renal tubular cell apoptosis in focal segmental glomerulosclerosis: roles of proteinuria and Fas-dependent pathways. J Am Soc Nephrol (2004) 1.06

Metabonomics of acute kidney injury in children after cardiac surgery. Pediatr Nephrol (2008) 1.06

Pilot double-blind, randomized controlled trial of short-term atorvastatin for prevention of acute kidney injury after cardiac surgery. Nephrology (Carlton) (2012) 1.05

Urine biochemistry in septic and non-septic acute kidney injury: a prospective observational study. J Crit Care (2012) 1.04

Early prediction of acute renal injury using urinary proteomics. Am J Nephrol (2005) 1.04

Identification of a urinary proteomic signature for lupus nephritis in children. Pediatr Nephrol (2007) 1.03

Progression from acute kidney injury to chronic kidney disease: a pediatric perspective. Adv Chronic Kidney Dis (2008) 1.02

Urinary markers of kidney injury and kidney function decline in HIV-infected women. J Acquir Immune Defic Syndr (2012) 1.01

Neutrophil gelatinase-associated lipocalin as a biomarker of cardiovascular disease: a systematic review. Clin Chem Lab Med (2012) 0.98

Review article: Renal support in critical illness. Can J Anaesth (2010) 0.97

Preoperative proteinuria predicts acute kidney injury in patients undergoing cardiac surgery. J Thorac Cardiovasc Surg (2011) 0.96

Dissociation of spectrin-ankyrin complex as a basis for loss of Na-K-ATPase polarity after ischemia. Am J Physiol Renal Physiol (2002) 0.95

Estradiol reverses TGF-beta1-induced mesangial cell apoptosis by a casein kinase 2-dependent mechanism. Kidney Int (2002) 0.95

Microarray analysis of focal segmental glomerulosclerosis. Am J Nephrol (2004) 0.94

Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis. Arthritis Res Ther (2011) 0.93