Published in PLoS One on April 02, 2008
Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. Cell Host Microbe (2009) 4.55
Assessment of biodosimetry methods for a mass-casualty radiological incident: medical response and management considerations. Health Phys (2013) 1.14
Prediction of in vivo radiation dose status in radiotherapy patients using ex vivo and in vivo gene expression signatures. Radiat Res (2011) 1.14
Laboratory intercomparison of gene expression assays. Radiat Res (2013) 1.10
Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. PLoS One (2010) 1.07
Plasma miRNA as biomarkers for assessment of total-body radiation exposure dosimetry. PLoS One (2011) 1.05
Whole mouse blood microRNA as biomarkers for exposure to γ-rays and (56)Fe ion. Int J Radiat Biol (2011) 1.03
DNA repair and cell cycle biomarkers of radiation exposure and inflammation stress in human blood. PLoS One (2012) 0.97
Radiation dose effect of DNA repair-related gene expression in mouse white blood cells. Med Sci Monit (2011) 0.93
Antibody-based screen for ionizing radiation-dependent changes in the Mammalian proteome for use in biodosimetry. Radiat Res (2009) 0.92
Gene expression response of mice after a single dose of 137CS as an internal emitter. Radiat Res (2014) 0.92
Gene expression signatures of radiation exposure in peripheral white blood cells of smokers and non-smokers. Int J Radiat Biol (2011) 0.91
A translatable predictor of human radiation exposure. PLoS One (2014) 0.90
Radiation-induced biomarkers for the detection and assessment of absorbed radiation doses. J Pharm Bioallied Sci (2010) 0.89
Radiation dose-rate effects on gene expression for human biodosimetry. BMC Med Genomics (2015) 0.88
Systemic signature of the lung response to respiratory syncytial virus infection. PLoS One (2011) 0.83
Toward the development of transcriptional biodosimetry for the identification of irradiated individuals and assessment of absorbed radiation dose. Radiat Environ Biophys (2015) 0.83
Identification of radiation-induced expression changes in nonimmortalized human T cells. Radiat Res (2010) 0.82
MicroRNA Expression for Early Prediction of Late Occurring Hematologic Acute Radiation Syndrome in Baboons. PLoS One (2016) 0.82
Deoxyribonucleic acid damage-associated biomarkers of ionising radiation: current status and future relevance for radiology and radiotherapy. Br J Radiol (2013) 0.80
Effect of 90Sr internal emitter on gene expression in mouse blood. BMC Genomics (2015) 0.80
Proton radiation-induced miRNA signatures in mouse blood: characterization and comparison with 56Fe-ion and gamma radiation. Int J Radiat Biol (2012) 0.80
Gene expression-based dosimetry by dose and time in mice following acute radiation exposure. PLoS One (2013) 0.79
Radiation injury treatment network (RITN): healthcare professionals preparing for a mass casualty radiological or nuclear incident. Int J Radiat Biol (2011) 0.79
Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry. Sci Rep (2016) 0.78
Embryonic ionizing radiation exposure results in expression alterations of genes associated with cardiovascular and neurological development, function, and disease and modified cardiovascular function in zebrafish. Front Genet (2014) 0.77
Application of multivariate modeling for radiation injury assessment: a proof of concept. Comput Math Methods Med (2014) 0.77
HEMODOSE: A Biodosimetry Tool Based on Multi-type Blood Cell Counts. Health Phys (2015) 0.76
Microfluidic module for blood cell separation for gene expression radiobiological assays. Radiat Prot Dosimetry (2015) 0.76
State-of-the-Art Advances in Radiation Biodosimetry for Mass Casualty Events Involving Radiation Exposure. Radiat Res (2016) 0.75
Peripheral blood signatures of lead exposure. PLoS One (2011) 0.75
GDF-15 gene expression alterations in human lymphoblastoid cells and peripheral blood lymphocytes following exposure to ionizing radiation. Mol Med Rep (2017) 0.75
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature (2000) 64.32
Allelic variation in human gene expression. Science (2002) 11.42
Retracted Genomic signatures to guide the use of chemotherapeutics. Nat Med (2006) 7.45
Retracted A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med (2006) 6.69
Individuality and variation in gene expression patterns in human blood. Proc Natl Acad Sci U S A (2003) 6.49
Medical management of the acute radiation syndrome: recommendations of the Strategic National Stockpile Radiation Working Group. Ann Intern Med (2004) 5.63
Major radiation exposure--what to expect and how to respond. N Engl J Med (2002) 5.41
Radiation dose to patients from cardiac diagnostic imaging. Circulation (2007) 5.10
Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood (2006) 5.05
Discovery and analysis of inflammatory disease-related genes using cDNA microarrays. Proc Natl Acad Sci U S A (1997) 4.82
Stereotyped and specific gene expression programs in human innate immune responses to bacteria. Proc Natl Acad Sci U S A (2002) 3.85
Colorectal screening after polypectomy: a national survey study of primary care physicians. Ann Intern Med (2006) 2.98
Mining gene expression profiles: expression signatures as cancer phenotypes. Nat Rev Genet (2007) 2.57
Gene expression signatures that predict radiation exposure in mice and humans. PLoS Med (2007) 2.38
Identification of potential mRNA biomarkers in peripheral blood lymphocytes for human exposure to ionizing radiation. Radiat Res (2000) 2.11
Human in vivo radiation-induced biomarkers: gene expression changes in radiotherapy patients. Cancer Res (2004) 2.04
Hematologic consequences of exposure to ionizing radiation. Exp Hematol (2002) 1.92
The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model. Proc Natl Acad Sci U S A (2004) 1.85
Transcriptional response of lymphoblastoid cells to ionizing radiation. Genome Res (2003) 1.77
CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells. Blood (2007) 1.69
Induction of gene expression as a monitor of exposure to ionizing radiation. Radiat Res (2001) 1.69
Genomic prediction of locoregional recurrence after mastectomy in breast cancer. J Clin Oncol (2006) 1.57
Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression. Circulation (2004) 1.56
p53 mutations in lung cancers from non-smoking atomic-bomb survivors. Lancet (1994) 1.56
Signatures of environmental exposures using peripheral leukocyte gene expression: tobacco smoke. Cancer Epidemiol Biomarkers Prev (2004) 1.44
Factor analysis for gene regulatory networks and transcription factor activity profiles. BMC Bioinformatics (2007) 1.44
Hormesis. A healthful dab of radiation? Science (2003) 1.32
High-sensitivity array analysis of gene expression for the early detection of disseminated breast tumor cells in peripheral blood. Proc Natl Acad Sci U S A (2001) 1.32
Circulating transcriptome reveals markers of atherosclerosis. Proc Natl Acad Sci U S A (2005) 1.27
The comparative radiation genetics of humans and mice. Annu Rev Genet (1990) 1.26
Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy. J Immunol (2006) 1.25
Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis. Mol Med (2007) 1.24
Long-term global gene expression patterns in irradiated human lymphocytes. Carcinogenesis (2003) 1.14
Blood genomics in human stroke. Stroke (2007) 1.05
Gene expression studies in systemic lupus erythematosus. Lupus (2006) 1.01
O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1. Cancer Res (2007) 0.96
Role of metallothionein in coagulatory disturbance and systemic inflammation induced by lipopolysaccharide in mice. FASEB J (2005) 0.95
Mutant frequency at the HPRT locus in peripheral blood T-lymphocytes of atomic bomb survivors. Mutat Res (1995) 0.91
Frequency of p53 mutations in hepatocellular carcinomas from atomic bomb survivors. J Natl Cancer Inst (1998) 0.87
Biological threat detection via host gene expression profiling. Clin Chem (2003) 0.83
Doses to nuclear technicians in a dedicated PET/CT centre utilising 18F fluorodeoxyglucose (FDG). Radiat Prot Dosimetry (2006) 0.81
Mouse DDA3 gene is a direct transcriptional target of p53 and p73. Oncogene (2002) 0.80
A study of the effects of exposure on cleanup workers at the Chernobyl nuclear reactor accident using multiple end points. Radiat Res (1997) 0.80
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature (2005) 19.56
Retracted Genomic signatures to guide the use of chemotherapeutics. Nat Med (2006) 7.45
Gene expression predictors of breast cancer outcomes. Lancet (2003) 6.99
Retracted A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med (2006) 6.69
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol (2004) 6.61
Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods (2005) 6.23
Retracted An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer. J Clin Oncol (2007) 5.77
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature (2009) 4.99
Implementing genomic medicine in the clinic: the future is here. Genet Med (2013) 4.89
Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. Cell Host Microbe (2009) 4.55
Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression. J Clin Oncol (2008) 4.45
High-Dimensional Sparse Factor Modeling: Applications in Gene Expression Genomics. J Am Stat Assoc (2008) 3.92
Gene expression phenotypic models that predict the activity of oncogenic pathways. Nat Genet (2003) 3.78
Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. Proc Natl Acad Sci U S A (2006) 3.73
Retracted Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial. Lancet Oncol (2007) 3.67
A pathway-based classification of human breast cancer. Proc Natl Acad Sci U S A (2010) 3.30
Retracted Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA (2008) 3.26
GATHER: a systems approach to interpreting genomic signatures. Bioinformatics (2006) 3.22
The SLCO1B1*5 genetic variant is associated with statin-induced side effects. J Am Coll Cardiol (2009) 3.10
An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer Cell (2008) 3.07
Risk factors for acute GVHD and survival after hematopoietic cell transplantation. Blood (2011) 3.02
A bistable Rb-E2F switch underlies the restriction point. Nat Cell Biol (2008) 2.91
The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med (2009) 2.91
E2Fs link the control of G1/S and G2/M transcription. EMBO J (2004) 2.81
Retracted Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer. J Clin Oncol (2007) 2.80
Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes. Proc Natl Acad Sci U S A (2004) 2.74
Gene expression profiling and genetic markers in glioblastoma survival. Cancer Res (2005) 2.63
Transforming epidemiology for 21st century medicine and public health. Cancer Epidemiol Biomarkers Prev (2013) 2.56
Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function. EMBO J (2002) 2.49
Gene expression signatures that predict radiation exposure in mice and humans. PLoS Med (2007) 2.38
Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers. Clin Cancer Res (2005) 2.37
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet (2010) 2.34
Linking oncogenic pathways with therapeutic opportunities. Nat Rev Cancer (2006) 2.32
Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease. Blood (2003) 2.31
An integrated clinico-metabolomic model improves prediction of death in sepsis. Sci Transl Med (2013) 2.23
Gene expression phenotypes of atherosclerosis. Arterioscler Thromb Vasc Biol (2004) 2.23
A genomic strategy to elucidate modules of oncogenic pathway signaling networks. Mol Cell (2009) 2.22
High heritability of metabolomic profiles in families burdened with premature cardiovascular disease. Mol Syst Biol (2009) 2.21
Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease. Biol Blood Marrow Transplant (2005) 2.12
The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research. J Biomed Inform (2010) 2.10
Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection. PLoS Genet (2011) 2.10
Personalized medicine: progress and promise. Annu Rev Genomics Hum Genet (2011) 2.06
Integrating diagnostics and therapeutics: revolutionizing drug discovery and patient care. Drug Discov Today (2002) 2.05
H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination. PLoS One (2011) 2.02
Radiologic and nuclear events: contingency planning for hematologists/oncologists. Blood (2008) 1.96
Epidermal growth factor regulates hematopoietic regeneration after radiation injury. Nat Med (2013) 1.95
Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. Nat Med (2010) 1.94
Correlation of peripheral-blood gene expression with the extent of coronary artery stenosis. Circ Cardiovasc Genet (2008) 1.92
Signaling networks that link cell proliferation and cell fate. J Biol Chem (2002) 1.91
Genomic medicine: a decade of successes, challenges, and opportunities. Sci Transl Med (2013) 1.89
Specificity in the activation and control of transcription factor E2F-dependent apoptosis. Proc Natl Acad Sci U S A (2003) 1.89
Endpoints for clinical trials testing treatment of acute graft-versus-host disease: a joint statement. Biol Blood Marrow Transplant (2009) 1.84
Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34. Blood (2005) 1.80
Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor. Mol Cell Biol (2003) 1.76
Embracing the complexity of genomic data for personalized medicine. Genome Res (2006) 1.75
Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy. Clin Cancer Res (2006) 1.72
Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation. Blood (2012) 1.71
Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription. J Biol Chem (2001) 1.70
Retracted A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. Proc Natl Acad Sci U S A (2008) 1.69
Gene expression patterns that characterize advanced stage serous ovarian cancers. J Soc Gynecol Investig (2004) 1.68
MicroRNAs and their target messenger RNAs associated with endometrial carcinogenesis. Gynecol Oncol (2008) 1.67
Partially matched, nonmyeloablative allogeneic transplantation: clinical outcomes and immune reconstitution. J Clin Oncol (2007) 1.65
Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. J Am Coll Cardiol (2013) 1.61
Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Dev Cell (2008) 1.59
High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients. Hepatology (2011) 1.59
Genomic prediction of locoregional recurrence after mastectomy in breast cancer. J Clin Oncol (2006) 1.57
Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling. J Gen Intern Med (2011) 1.56
Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo. Blood (2009) 1.52
Public knowledge of and attitudes toward genetics and genetic testing. Genet Test Mol Biomarkers (2013) 1.52
Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proc Natl Acad Sci U S A (2002) 1.51
Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse. Blood (2007) 1.49
A national clinical decision support infrastructure to enable the widespread and consistent practice of genomic and personalized medicine. BMC Med Inform Decis Mak (2009) 1.49
Novel tumor sampling strategies to enable microarray gene expression signatures in breast cancer: a study to determine feasibility and reproducibility in the context of clinical care. Breast Cancer Res Treat (2009) 1.46
The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells. J Biol Chem (2003) 1.46