PubRank

Gilbert Di Paolo

Author PubWeight™ 80.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk. Neuron 2013 4.67
3 The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron 2007 2.36
4 Inhibitory effect of dietary lipids on chaperone-mediated autophagy. Proc Natl Acad Sci U S A 2012 1.97
5 The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes. Mol Cell 2010 1.97
6 Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis. Sci Signal 2012 1.86
7 Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J Biol Chem 2012 1.79
8 The stimulatory action of amphiphysin on dynamin function is dependent on lipid bilayer curvature. EMBO J 2004 1.72
9 Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry. Nat Biotechnol 2003 1.64
10 The role of lipids in the control of autophagy. Curr Biol 2013 1.59
11 The phospholipase D1 pathway modulates macroautophagy. Nat Commun 2010 1.56
12 Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome. Proc Natl Acad Sci U S A 2008 1.54
13 Comparative lipidomic analysis of mouse and human brain with Alzheimer disease. J Biol Chem 2011 1.51
14 Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. J Neurosci 2010 1.49
15 Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism. Proc Natl Acad Sci U S A 2006 1.48
16 Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases. J Cell Biol 2005 1.47
17 Competition for talin results in trans-dominant inhibition of integrin activation. J Biol Chem 2004 1.46
18 Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism. Nat Neurosci 2008 1.46
19 Synaptojanin 1-mediated PI(4,5)P2 hydrolysis is modulated by membrane curvature and facilitates membrane fission. Dev Cell 2011 1.44
20 Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout mice. Proc Natl Acad Sci U S A 2002 1.42
21 Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain. J Biol Chem 2003 1.37
22 Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion. Proc Natl Acad Sci U S A 2005 1.32
23 SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2. J Cell Sci 2008 1.31
24 Lipids and lipid modifications in the regulation of membrane traffic. Curr Opin Cell Biol 2007 1.30
25 Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis. PLoS One 2013 1.28
26 Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system. Nat Commun 2013 1.27
27 Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol 2009 1.23
28 The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures. Hum Mutat 2013 1.17
29 The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport. Neurobiol Dis 2012 1.14
30 Phospholipase D in brain function and Alzheimer's disease. Biochim Biophys Acta 2010 1.06
31 A role for talin in presynaptic function. J Cell Biol 2004 1.05
32 Cholesterol modulates ion channels via down-regulation of phosphatidylinositol 4,5-bisphosphate. J Neurochem 2009 1.01
33 Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes. Hum Mol Genet 2012 0.99
34 Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease. J Neurosci 2012 0.96
35 Regulation of transferrin recycling kinetics by PtdIns[4,5]P2 availability. FASEB J 2006 0.93
36 Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment. PLoS One 2013 0.92
37 Role of phosphoinositides at the neuronal synapse. Subcell Biochem 2012 0.87
38 Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice. Hum Mol Genet 2012 0.86
39 Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization. J Lipid Res 2012 0.85
40 PI5P migrates out of the PIP shadow. EMBO Rep 2012 0.82
41 PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models. J Clin Invest 2016 0.81
42 A lipid kinase controls the maintenance of dendritic spines. EMBO J 2009 0.79
43 Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest 2016 0.79
44 A novel role for phospholipase D as an endogenous negative regulator of platelet sensitivity. Cell Signal 2012 0.78
45 Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3. J Biol Chem 2013 0.77
46 Screening assay for small-molecule inhibitors of synaptojanin 1, a synaptic phosphoinositide phosphatase. J Biomol Screen 2013 0.77
47 Acute manipulation of phosphoinositide levels in cells. Methods Cell Biol 2012 0.77
48 Knockout punch: cardiolipin oxidation in trauma. Nat Neurosci 2012 0.76
49 Erratum: Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol-3-phosphate-specific phospholipase A1 activity. Nat Commun 2015 0.75