Charles W Emala

Author PubWeight™ 72.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Anaphylaxis and anesthesia: controversies and new insights. Anesthesiology 2009 2.40
2 A3 adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis. Am J Physiol Regul Integr Comp Physiol 2006 1.94
3 Targeting the restricted α-subunit repertoire of airway smooth muscle GABAA receptors augments airway smooth muscle relaxation. Am J Physiol Lung Cell Mol Physiol 2011 1.92
4 Differential protective effects of volatile anesthetics against renal ischemia-reperfusion injury in vivo. Anesthesiology 2004 1.65
5 Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation. Anesthesiology 2009 1.55
6 Propofol preferentially relaxes neurokinin receptor-2-induced airway smooth muscle contraction in guinea pig trachea. Anesthesiology 2010 1.45
7 GABAA receptors are expressed and facilitate relaxation in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2008 1.43
8 A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion. Am J Physiol Renal Physiol 2003 1.38
9 A1 adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 2004 1.36
10 Isoflurane mediates protection from renal ischemia-reperfusion injury via sphingosine kinase and sphingosine-1-phosphate-dependent pathways. Am J Physiol Renal Physiol 2007 1.34
11 Isoflurane improves survival and protects against renal and hepatic injury in murine septic peritonitis. Shock 2007 1.32
12 Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration in mice. Am J Physiol Renal Physiol 2007 1.30
13 Adenosine attenuates oxidant injury in human proximal tubular cells via A(1) and A(2a) adenosine receptors. Am J Physiol Renal Physiol 2002 1.28
14 Anti-inflammatory and antinecrotic effects of the volatile anesthetic sevoflurane in kidney proximal tubule cells. Am J Physiol Renal Physiol 2006 1.25
15 Propofol directly increases tau phosphorylation. PLoS One 2011 1.25
16 Acute and delayed renal protection against renal ischemia and reperfusion injury with A1 adenosine receptors. Am J Physiol Renal Physiol 2007 1.20
17 A1 adenosine receptor knockout mice exhibit increased mortality, renal dysfunction, and hepatic injury in murine septic peritonitis. Am J Physiol Renal Physiol 2005 1.19
18 Functional expression of the GABAB receptor in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2006 1.14
19 A3 adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure. Am J Physiol Renal Physiol 2002 1.13
20 Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation. Am J Physiol Lung Cell Mol Physiol 2008 1.13
21 TGF-beta1 release by volatile anesthetics mediates protection against renal proximal tubule cell necrosis. Am J Nephrol 2007 1.12
22 Preconditioning and adenosine protect human proximal tubule cells in an in vitro model of ischemic injury. J Am Soc Nephrol 2002 1.07
23 The GABAA agonist muscimol attenuates induced airway constriction in guinea pigs in vivo. J Appl Physiol (1985) 2009 1.06
24 Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS. Am J Physiol Lung Cell Mol Physiol 2005 1.04
25 Functional expression of GABAB receptors in airway epithelium. Am J Respir Cell Mol Biol 2008 1.04
26 Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle. FASEB J 2011 1.04
27 Rapacuronium preferentially antagonizes the function of M2 versus M3 muscarinic receptors in guinea pig airway smooth muscle. Anesthesiology 2005 1.03
28 Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metab 2013 1.00
29 Neuromuscular blocking agents' differential bronchoconstrictive potential in Guinea pig airways. Anesthesiology 2007 0.99
30 beta2-Adrenergic receptor genotype and preterm delivery. Am J Obstet Gynecol 2002 0.98
31 Leptin repletion restores depressed {beta}-adrenergic contractility in ob/ob mice independently of cardiac hypertrophy. J Physiol 2005 0.98
32 Local anesthetics reduce mortality and protect against renal and hepatic dysfunction in murine septic peritonitis. Anesthesiology 2004 0.96
33 Characterization of adenosine receptors in human kidney proximal tubule (HK-2) cells. Exp Nephrol 2002 0.94
34 Can we find better bronchodilators to relieve asthma symptoms? J Allergy (Cairo) 2012 0.94
35 Sevoflurane-mediated TGF-beta1 signaling in renal proximal tubule cells. Am J Physiol Renal Physiol 2007 0.92
36 Inhibition of histamine-induced bronchoconstriction in Guinea pig and Swine by pulsed electrical vagus nerve stimulation. Neuromodulation 2009 0.92
37 Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2008 0.91
38 Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2013 0.91
39 Effects of ginger and its constituents on airway smooth muscle relaxation and calcium regulation. Am J Respir Cell Mol Biol 2012 0.89
40 Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle. Am J Respir Cell Mol Biol 2011 0.88
41 Inducible nitric oxide synthase promoter polymorphism affords protection against cognitive dysfunction after carotid endarterectomy. Stroke 2009 0.88
42 Intra-arterial drug delivery: a concise review. J Neurosurg Anesthesiol 2007 0.88
43 Oxidant preconditioning protects human proximal tubular cells against lethal oxidant injury via p38 MAPK and heme oxygenase-1. Am J Nephrol 2003 0.88
44 Case scenario: bronchospasm during anesthetic induction. Anesthesiology 2011 0.87
45 Functional expression of γ-amino butyric acid transporter 2 in human and guinea pig airway epithelium and smooth muscle. Am J Respir Cell Mol Biol 2010 0.87
46 Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone. Am J Physiol Lung Cell Mol Physiol 2012 0.86
47 Active components of ginger potentiate β-agonist-induced relaxation of airway smooth muscle by modulating cytoskeletal regulatory proteins. Am J Respir Cell Mol Biol 2014 0.84
48 Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4. Am J Physiol Lung Cell Mol Physiol 2013 0.84
49 Expression and muscarinic receptor coupling of Lyn kinase in cultured human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2005 0.82
50 Reverse remodeling and enhanced adrenergic reserve from passive external support in experimental dilated heart failure. J Am Coll Cardiol 2002 0.82
51 Rapacuronium augments acetylcholine-induced bronchoconstriction via positive allosteric interactions at the M3 muscarinic receptor. Anesthesiology 2005 0.81
52 A mechanism for rapacuronium-induced bronchospasm: M2 muscarinic receptor antagonism. Anesthesiology 2003 0.81
53 Antagonists of the TMEM16A calcium-activated chloride channel modulate airway smooth muscle tone and intracellular calcium. Anesthesiology 2015 0.81
54 Chloride channel blockers promote relaxation of TEA-induced contraction in airway smooth muscle. J Smooth Muscle Res 2013 0.80
55 Raf-1 kinase mediates adenylyl cyclase sensitization by TNF-alpha in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2007 0.79
56 Interactive effect of cigarette smoke extract and world trade center dust particles on airway cell cytotoxicity. J Toxicol Environ Health A 2011 0.79
57 The dopamine D1 receptor is expressed and facilitates relaxation in airway smooth muscle. Respir Res 2013 0.79
58 Local anesthetics worsen renal function after ischemia-reperfusion injury in rats. Am J Physiol Renal Physiol 2003 0.79
59 Low voltage vagal nerve stimulation reduces bronchoconstriction in guinea pigs through catecholamine release. Neuromodulation 2012 0.79
60 The dopamine D(2) receptor is expressed and sensitizes adenylyl cyclase activity in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2011 0.79
61 Chloride in airway smooth muscle: the ignored anion no longer? Am J Physiol Lung Cell Mol Physiol 2012 0.78
62 Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation. Sci Rep 2013 0.78
63 Pre-exposure to vasopressin potentiates the vasoconstrictive effect of epinephrine in rat aorta isolated during late anaphylaxis. Shock 2010 0.78
64 Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system. Assay Drug Dev Technol 2012 0.77
65 Beta-2 adrenoceptor genotype and progress in term and late preterm active labor. Am J Obstet Gynecol 2011 0.77
66 Tumor necrosis factor alpha stimulates adenylyl cyclase activity in human myometrial cells. Biol Reprod 2003 0.77
67 Anesthetic effects on γ-aminobutyric acid A receptors: not just on your nerves. Anesthesiology 2013 0.76
68 The anti-asthma herbal medicine ASHMI acutely inhibits airway smooth muscle contraction via prostaglandin E2 activation of EP2/EP4 receptors. Am J Physiol Lung Cell Mol Physiol 2013 0.76
69 Renal protection with isoflurane. Anesth Analg 2006 0.75
70 Microvascular blood flow in the airway mucosa modulates bronchoconstriction. J Appl Physiol (1985) 2010 0.75
71 Desflurane and neural control of airway tone. Can J Anaesth 2011 0.75
72 Gantacurium and CW002 do not potentiate muscarinic receptor-mediated airway smooth muscle constriction in guinea pigs. Anesthesiology 2010 0.75