Published in Neurochem Res on April 16, 2008
Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev (2010) 4.02
Inflammation in neurodegenerative diseases. Immunology (2010) 3.22
Structure-guided design of selective inhibitors of neuronal nitric oxide synthase. J Med Chem (2013) 1.00
Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials. Acta Neuropathol (2014) 0.99
Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century. Curr Neuropharmacol (2013) 0.97
3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced iNOS Expression by Suppressing NF-κB Activation in BV2 Microglial Cells. Korean J Physiol Pharmacol (2012) 0.95
Neuroprotective effects of berry fruits on neurodegenerative diseases. Neural Regen Res (2014) 0.92
Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations. J Am Chem Soc (2012) 0.91
Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system. Oxid Med Cell Longev (2012) 0.89
Morin exerts neuroprotective actions in Parkinson disease models in vitro and in vivo. Acta Pharmacol Sin (2010) 0.88
Caloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration. Int J Cell Biol (2012) 0.85
Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers. J Med Chem (2013) 0.84
Anti-inflammatory Activity of 1-docosanoyl Cafferate Isolated from Rhus verniciflua in LPS-stimulated BV2 Microglial Cells. Korean J Physiol Pharmacol (2011) 0.83
Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells. J Clin Biochem Nutr (2012) 0.82
The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila. PLoS One (2012) 0.82
Inhibition of age-related cytokines production by ATGL: a mechanism linked to the anti-inflammatory effect of resveratrol. Mediators Inflamm (2014) 0.80
Recent advances toward improving the bioavailability of neuronal nitric oxide synthase inhibitors. Curr Top Med Chem (2013) 0.79
Improving active and passive avoidance memories deficits due to permanent cerebral ischemia by pomegranate seed extract in female rats. Malays J Med Sci (2013) 0.79
Ontogenesis of NADPH-diaphorase positive neurons in guinea pig neocortex. Front Neuroanat (2015) 0.78
Neuronal nitric oxide synthase (NOS1) polymorphisms interact with financial hardship to affect depression risk. Neuropsychopharmacology (2014) 0.78
Nitric Oxide Synthase Inhibitor Improves De Novo and Long-Term l-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats. Front Syst Neurosci (2011) 0.78
Pomegranate seed hydroalcoholic extract improves memory deficits in ovariectomized rats with permanent cerebral hypoperfusion /ischemia. Avicenna J Phytomed (2015) 0.77
Excessive levels of nitric oxide in rat model of Parkinson's disease induced by rotenone. Exp Ther Med (2014) 0.77
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker. J Med Chem (2016) 0.77
LPS induces mediators of neuroinflammation, cell proliferation, and GFAP expression in human astrocytoma cells U373MG: the anti-inflammatory and anti-proliferative effect of guggulipid. Neurol Sci (2013) 0.76
Improvement in Memory and Brain Long-term Potentiation Deficits Due to Permanent Hypoperfusion/Ischemia by Grape Seed Extract in Rats. Iran J Basic Med Sci (2013) 0.76
Red Lentil Extract: Neuroprotective Effects on Perphenazine Induced Catatonia in Rats. J Clin Diagn Res (2016) 0.75
The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review. PLoS One (2016) 0.75
The Anti-Cancer Effect of Polyphenols against Breast Cancer and Cancer Stem Cells: Molecular Mechanisms. Nutrients (2016) 0.75
Redox Imbalance and Viral Infections in Neurodegenerative Diseases. Oxid Med Cell Longev (2016) 0.75
Recent Advances in the Study of Bipolar/Rod-Shaped Microglia and their Roles in Neurodegeneration. Front Aging Neurosci (2017) 0.75
Alzheimer's Disease Risk and Progression: The Role of Nutritional Supplements and their Effect on Drug Therapy Outcome. Curr Neuropharmacol (2016) 0.75
Hepatoprotective and Antioxidant Potential of Organic and Conventional Grape Juices in Rats Fed a High-Fat Diet. Antioxidants (Basel) (2014) 0.75
The impact of high and low dose ionising radiation on the central nervous system. Redox Biol (2016) 0.75
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation. Proc Natl Acad Sci U S A (2002) 2.35
Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J Biol Chem (2010) 1.71
Cell signalling and the glutathione redox system. Biochem Pharmacol (2002) 1.68
High-affinity Zn2+ uptake system ZnuABC is required for bacterial zinc homeostasis in intracellular environments and contributes to the virulence of Salmonella enterica. Infect Immun (2007) 1.68
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. Proc Natl Acad Sci U S A (2006) 1.67
Glutathione limits Ero1-dependent oxidation in the endoplasmic reticulum. J Biol Chem (2004) 1.58
Limited sampling strategies for the estimation of atazanavir daily exposure in HIV-infected patients. Fundam Clin Pharmacol (2011) 1.38
Mitochondrial dysfunction in neurodegenerative diseases associated with copper imbalance. Neurochem Res (2004) 1.29
Redox implications of AMPK-mediated signal transduction beyond energetic clues. J Cell Sci (2012) 1.28
Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response. J Immunol (2009) 1.25
Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway. FASEB J (2002) 1.23
Inter- and intra-patient variability of raltegravir pharmacokinetics in HIV-1-infected subjects. J Antimicrob Chemother (2011) 1.22
Pro-apoptotic activity of novel Isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage. J Biol Chem (2007) 1.20
Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells. Free Radic Biol Med (2005) 1.19
TCA Cycle Defects and Cancer: When Metabolism Tunes Redox State. Int J Cell Biol (2012) 1.17
Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide. Cancer Res (2003) 1.17
Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site. J Biol Chem (2004) 1.15
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells. FASEB J (2004) 1.14
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals. Brain Res Bull (2003) 1.12
p53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance. Antioxid Redox Signal (2012) 1.12
Proapoptotic activity of new glutathione S-transferase inhibitors. Cancer Res (2005) 1.10
Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug. J Bioenerg Biomembr (2012) 1.08
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2. FASEB J (2003) 1.07
Isatin-Schiff base copper(II) complexes and their influence on cellular viability. J Inorg Biochem (2005) 1.06
Under the ROS…thiol network is the principal suspect for autophagy commitment. Autophagy (2010) 1.04
Linezolid plasma concentrations and occurrence of drug-related haematological toxicity in patients with gram-positive infections. Int J Antimicrob Agents (2013) 1.02
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. J Cell Physiol (2011) 1.00
Nitric oxide is the primary mediator of cytotoxicity induced by GSH depletion in neuronal cells. J Cell Sci (2011) 1.00
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. FASEB J (2006) 1.00
Redox mechanisms involved in the selective activation of Nrf2-mediated resistance versus p53-dependent apoptosis in adenocarcinoma cells. J Biol Chem (2009) 0.99
Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease. Neurobiol Aging (2010) 0.99
p38(MAPK) and ERK1/2 dictate cell death/survival response to different pro-oxidant stimuli via p53 and Nrf2 in neuroblastoma cells SH-SY5Y. Biochem Pharmacol (2012) 0.98
Periplasmic competition for zinc uptake between the metallochaperone ZnuA and Cu,Zn superoxide dismutase. FEBS Lett (2004) 0.98
Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence. J Biol Chem (2008) 0.97
Synthesis, oxidant properties, and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells. J Med Chem (2009) 0.96
ABCB1 genotypes predict cyclosporine-related adverse events and kidney allograft outcome. J Am Soc Nephrol (2009) 0.94
Copper-dependent toxicity in SH-SY5Y neuroblastoma cells involves mitochondrial damage. Biochem Biophys Res Commun (2005) 0.93
Nuclear recruitment of neuronal nitric-oxide synthase by α-syntrophin is crucial for the induction of mitochondrial biogenesis. J Biol Chem (2013) 0.93
Double-strand DNA cleavage induced by oxindole-Schiff base copper(II) complexes with potential antitumor activity. J Inorg Biochem (2008) 0.92
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1. Cancer Res (2012) 0.92
Reactive oxygen species mediate p53 activation and apoptosis induced by sodium nitroprusside in SH-SY5Y cells. Mol Pharmacol (2008) 0.91
Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice. Vaccine (2008) 0.91
Low body weight in females is a risk factor for increased tenofovir exposure and drug-related adverse events. PLoS One (2013) 0.90
p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration. Biochem J (2010) 0.90
Antiapoptotic response to induced GSH depletion: involvement of heat shock proteins and NF-kappaB activation. Antioxid Redox Signal (2005) 0.89
Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells. Autophagy (2012) 0.89
Glutathione-related systems and modulation of extracellular signal-regulated kinases are involved in the resistance of AGS adenocarcinoma gastric cells to diallyl disulfide-induced apoptosis. Cancer Res (2005) 0.88
Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS. Cell Microbiol (2014) 0.87
Rhodanese-thioredoxin system and allyl sulfur compounds. FEBS J (2008) 0.87
Superoxide dismutase 1 modulates expression of transferrin receptor. J Biol Inorg Chem (2006) 0.86
Limited sampling strategies for the estimation of raltegravir daily exposure in HIV-infected patients. J Clin Pharmacol (2011) 0.86
Glutathione and copper, zinc superoxide dismutase are modulated by overexpression of neuronal nitric oxide synthase. Int J Biochem Cell Biol (2008) 0.86
Differential contribution of sodC1 and sodC2 to intracellular survival and pathogenicity of Salmonella enterica serovar Choleraesuis. Microbes Infect (2005) 0.86
Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS. J Neurochem (2003) 0.86
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets. Antioxid Redox Signal (2011) 0.86
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. Int J Biochem Cell Biol (2010) 0.86
Caloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration. Int J Cell Biol (2012) 0.85
Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells. J Biol Chem (2002) 0.85
Overexpression of superoxide dismutase 1 protects against beta-amyloid peptide toxicity: effect of estrogen and copper chelators. Neurochem Int (2004) 0.84
Exposure-related effects of atazanavir on the pharmacokinetics of raltegravir in HIV-1-infected patients. Ther Drug Monit (2010) 0.84
trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis. Biochem Pharmacol (2008) 0.84
Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in neurodegenerative processes. IUBMB Life (2004) 0.84
Garlic-derived diallyl disulfide modulates peroxisome proliferator activated receptor gamma co-activator 1 alpha in neuroblastoma cells. Biochem Pharmacol (2012) 0.84
Breakfast: a multidisciplinary approach. Ital J Pediatr (2013) 0.83
Copper imbalance and oxidative stress in neurodegeneration. Ital J Biochem (2007) 0.83
Glutathione is a crucial guardian of protein integrity in the brain upon nitric oxide imbalance. Commun Integr Biol (2011) 0.83
Carcinoma cells activate AMP-activated protein kinase-dependent autophagy as survival response to kaempferol-mediated energetic impairment. Autophagy (2010) 0.83
Distinctive functional features in prokaryotic and eukaryotic Cu,Zn superoxide dismutases. Biol Chem (2004) 0.83
Comparison of the in vivo pharmacokinetics and in vitro dissolution of raltegravir in HIV patients receiving the drug by swallowing or by chewing. Antimicrob Agents Chemother (2012) 0.83
Regulatory and structural properties differentiating the chromosomal and the bacteriophage-associated Escherichia coli O157:H7 Cu, Zn superoxide dismutases. BMC Microbiol (2008) 0.82
Pharmacokinetics of mycophenolate sodium and comparison with the mofetil formulation in stable kidney transplant recipients. Clin J Am Soc Nephrol (2007) 0.82
Therapeutic drug monitoring of sirolimus: effect of concomitant immunosuppressive therapy and optimization of drug dosing. Am J Transplant (2004) 0.82
Deprive to kill: glutamine closes the gate to anticancer monocarboxylic drugs. Autophagy (2012) 0.81
Activity of protein phosphatase calcineurin is decreased in sporadic and familial amyotrophic lateral sclerosispatients. J Neurochem (2004) 0.81
Selenium- and zinc-deficient cardiomyopathy in human intestinal malabsorption: preliminary results of selenium/zinc infusion. Eur J Heart Fail (2011) 0.81
Low-Shear Modeled Microgravity Enhances Salmonella Enterica Resistance to Hydrogen Peroxide Through a Mechanism Involving KatG and KatN. Open Microbiol J (2012) 0.81