Published in Arterioscler Thromb Vasc Biol on May 01, 2008
Epicardial-myocardial signaling directing coronary vasculogenesis. Circ Res (2010) 1.46
The role of the prokineticin 2 pathway in human reproduction: evidence from the study of human and murine gene mutations. Endocr Rev (2010) 1.16
Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27. PLoS One (2011) 1.05
The embryonic epicardium: an essential element of cardiac development. J Cell Mol Med (2010) 1.02
Coronary vessel development and insight towards neovascular therapy. Int J Exp Pathol (2009) 1.00
Prokineticin 2 is an endangering mediator of cerebral ischemic injury. Proc Natl Acad Sci U S A (2012) 0.90
Prokineticin receptor 1 as a novel suppressor of preadipocyte proliferation and differentiation to control obesity. PLoS One (2013) 0.88
Prokineticin receptor-1 is a new regulator of endothelial insulin uptake and capillary formation to control insulin sensitivity and cardiovascular and kidney functions. J Am Heart Assoc (2013) 0.88
The adult epicardium: realizing the potential for neovascular therapy. Arterioscler Thromb Vasc Biol (2008) 0.86
The epicardium as a candidate for heart regeneration. Future Cardiol (2012) 0.85
Molecular characterization of EG-VEGF-mediated angiogenesis: differential effects on microvascular and macrovascular endothelial cells. Mol Biol Cell (2010) 0.83
Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1. PLoS One (2015) 0.80
Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development. Sci Rep (2016) 0.78
Gene and cell therapy for heart failure. Antioxid Redox Signal (2009) 0.77
More than Just a Simple Cardiac Envelope; Cellular Contributions of the Epicardium. Front Cell Dev Biol (2017) 0.75
Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis. Int J Endocrinol (2017) 0.75
Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity. Sci Rep (2015) 0.75
Prokineticin Is a New Linker between Obesity and Cardiovascular Diseases. Front Cardiovasc Med (2017) 0.75
Approaches to augment vascularisation and regeneration of the adult heart via the reactivated epicardium. Glob Cardiol Sci Pract (2016) 0.75
Prokineticin receptor-1-dependent paracrine and autocrine pathways control cardiac tcf21(+) fibroblast progenitor cell transformation into adipocytes and vascular cells. Sci Rep (2017) 0.75
Projection of an immunological self shadow within the thymus by the aire protein. Science (2002) 12.15
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature (2006) 9.36
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell (2002) 3.36
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse. EMBO J (2003) 2.94
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A (2004) 2.46
The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP. Mol Cell Biol (2002) 2.40
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. EMBO J (2006) 2.28
Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. Nat Genet (2005) 2.24
Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proc Natl Acad Sci U S A (2009) 2.08
Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proc Natl Acad Sci U S A (2006) 1.95
Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin. Proc Natl Acad Sci U S A (2005) 1.92
The lipid phosphatase myotubularin is essential for skeletal muscle maintenance but not for myogenesis in mice. Proc Natl Acad Sci U S A (2002) 1.91
Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy. Nat Med (2011) 1.87
T-tubule disorganization and defective excitation-contraction coupling in muscle fibers lacking myotubularin lipid phosphatase. Proc Natl Acad Sci U S A (2009) 1.83
Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouse. Genesis (2004) 1.61
Myelin/oligodendrocyte glycoprotein-deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice. J Clin Invest (2003) 1.59
Helios deficiency has minimal impact on T cell development and function. J Immunol (2009) 1.50
Transgenic myocardial overexpression of prokineticin receptor-2 (GPR73b) induces hypertrophy and capillary vessel leakage. Cardiovasc Res (2008) 1.50
PU.1 determines the self-renewal capacity of erythroid progenitor cells. Blood (2004) 1.48
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure. Proc Natl Acad Sci U S A (2007) 1.46
A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development. Proc Natl Acad Sci U S A (2006) 1.46
Liver receptor homolog 1 is essential for ovulation. Genes Dev (2008) 1.45
AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis. Hum Mol Genet (2008) 1.44
TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor. J Biol Chem (2004) 1.42
P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis. EMBO J (2008) 1.38
Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled. EMBO J (2002) 1.36
Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation. Proc Natl Acad Sci U S A (2009) 1.33
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration. Nat Chem Biol (2012) 1.32
Ikaros is critical for B cell differentiation and function. Eur J Immunol (2002) 1.32
G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. J Biol Chem (2005) 1.27
Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation. J Invest Dermatol (2008) 1.23
Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation. J Biol Chem (2007) 1.21
Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. J Med Chem (2009) 1.19
Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes. Genes Dev (2006) 1.19
Sphingosine 1-phosphate induces membrane ruffling and increases motility of human umbilical vein endothelial cells via vascular endothelial growth factor receptor and CrkII. J Biol Chem (2002) 1.19
The prokineticin receptor-1 (GPR73) promotes cardiomyocyte survival and angiogenesis. FASEB J (2007) 1.18
Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice. Proc Natl Acad Sci U S A (2002) 1.14
Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia. Dis Model Mech (2012) 1.13
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy. Circ Res (2002) 1.13
Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Circ Res (2010) 1.12
TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis. Dev Biol (2005) 1.11
Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states. J Pharmacol Exp Ther (2002) 1.10
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes. J Invest Dermatol (2007) 1.09
G(i/o) protein-dependent and -independent actions of Pertussis Toxin (PTX). Toxins (Basel) (2011) 1.08
Prohibitin ligands in cell death and survival: mode of action and therapeutic potential. Chem Biol (2013) 1.08
Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor. Mol Endocrinol (2007) 1.08
Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells. Oncogene (2005) 1.07
Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms. Cell Signal (2007) 1.07
Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27. PLoS One (2011) 1.05
Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5-HT2B receptor signaling. FASEB J (2003) 1.04
S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN. Biochem Biophys Res Commun (2007) 1.04
Mechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells. J Biol Chem (2009) 1.04
Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway. Hum Mol Genet (2010) 1.02
The first cellular models based on frataxin missense mutations that reproduce spontaneously the defects associated with Friedreich ataxia. PLoS One (2009) 1.02
Roles of TRP channels in the development of cardiac hypertrophy. Naunyn Schmiedebergs Arch Pharmacol (2008) 1.02
Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy. Circulation (2003) 1.01
Herpes simplex virus 1 amplicon vector-mediated siRNA targeting epidermal growth factor receptor inhibits growth of human glioma cells in vivo. Mol Ther (2005) 1.01
Divergent roles of prokineticin receptors in the endothelial cells: angiogenesis and fenestration. Am J Physiol Heart Circ Physiol (2009) 1.00
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. J Biol Chem (2005) 1.00
Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition. J Biol Chem (2010) 0.98
Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation. Mol Pharmacol (2003) 0.98
Myocytic androgen receptor controls the strength but not the mass of limb muscles. Proc Natl Acad Sci U S A (2010) 0.98
Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia. Biochim Biophys Acta (2008) 0.97
Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine D(2) receptors. Mol Endocrinol (2010) 0.97
Involvement of ERK MAP kinase in endoplasmic reticulum stress in SH-SY5Y human neuroblastoma cells. J Neurochem (2004) 0.96
A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells. PLoS One (2013) 0.96
Beta-arrestin2 enhances beta2-adrenergic receptor-mediated nuclear translocation of ERK. Cell Signal (2005) 0.96
Training and aging modulate the loss-of-balance phenotype observed in a new ENU-induced allele of Otopetrin1. Biol Cell (2005) 0.95
Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells. Cell Signal (2005) 0.95
TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts. Biochem Biophys Res Commun (2011) 0.93
BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response. Cell Metab (2012) 0.93
Flavaglines as potent anticancer and cytoprotective agents. J Med Chem (2012) 0.92
Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models. Dis Model Mech (2012) 0.92
Conditional ablation of integrin alpha-6 in mouse epidermis leads to skin fragility and inflammation. Eur J Cell Biol (2010) 0.92
GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance. Nat Commun (2013) 0.92
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RARgamma) gene. Genesis (2002) 0.91
Clathrin required for phosphorylation and internalization of beta2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2). J Biol Chem (2006) 0.91
Activation mechanism of Gi and Go by reactive oxygen species. J Biol Chem (2002) 0.91
An integrated diagnosis strategy for congenital myopathies. PLoS One (2013) 0.91
Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis. Biol Open (2012) 0.91
Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced anti-inflammatory actions in endothelial cells. J Immunol (2008) 0.90
Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background. Genesis (2012) 0.89
Prokineticin receptor 1 as a novel suppressor of preadipocyte proliferation and differentiation to control obesity. PLoS One (2013) 0.88
Thromboxane A2 receptor-mediated G12/13-dependent glial morphological change. Eur J Pharmacol (2006) 0.88
Rescue of morphogenetic defects and of retinoic acid signaling in retinaldehyde dehydrogenase 2 (Raldh2) mouse mutants by chimerism with wild-type cells. Differentiation (2006) 0.88
Prokineticin receptor-1 is a new regulator of endothelial insulin uptake and capillary formation to control insulin sensitivity and cardiovascular and kidney functions. J Am Heart Assoc (2013) 0.88
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor beta (RARbeta) gene. Genesis (2002) 0.88
Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells. J Immunol (2010) 0.88