Published in Dev Biol on March 26, 2008
Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol (2009) 2.86
Vertebrate endoderm development and organ formation. Annu Rev Cell Dev Biol (2009) 2.67
Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am J Hum Genet (2013) 1.26
FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. EMBO J (2011) 1.11
Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos. PLoS One (2009) 1.00
Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation. Genes Dev (2008) 0.98
Anterior visceral endoderm directs ventral morphogenesis and placement of head and heart via BMP2 expression. Dev Cell (2011) 0.98
Latrophilins function as heterophilic cell-adhesion molecules by binding to teneurins: regulation by alternative splicing. J Biol Chem (2013) 0.98
The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis. Development (2011) 0.92
FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development. Neuron (2014) 0.92
Structural basis of latrophilin-FLRT interaction. Structure (2015) 0.86
Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo. Philos Trans R Soc Lond B Biol Sci (2014) 0.84
Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling. PLoS One (2010) 0.81
Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure (2015) 0.81
Genetic dissection of ventral folding morphogenesis in mouse: embryonic visceral endoderm-supplied BMP2 positions head and heart. Curr Opin Genet Dev (2013) 0.79
Super-complexes of adhesion GPCRs and neural guidance receptors. Nat Commun (2016) 0.77
A novel fibroblast growth factor receptor family member promotes neuronal outgrowth and synaptic plasticity in aplysia. Amino Acids (2014) 0.77
Ion channels, guidance molecules, intracellular signaling and transcription factors regulating nervous and vascular system development. J Physiol Sci (2015) 0.76
Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis. Biol Open (2012) 0.76
An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell (2007) 3.74
Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection. Science (2012) 3.39
Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol (2009) 2.86
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2. Nat Struct Mol Biol (2008) 2.58
Glycoprotein structural genomics: solving the glycosylation problem. Structure (2007) 2.40
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone. Genes Dev (2008) 2.33
Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo. Development (2004) 2.28
The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development (2005) 2.23
Pluripotency factors regulate definitive endoderm specification through eomesodermin. Genes Dev (2011) 2.22
Nodal activity in the node governs left-right asymmetry. Genes Dev (2002) 1.95
Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development (2008) 1.94
Cell fate decisions within the mouse organizer are governed by graded Nodal signals. Genes Dev (2003) 1.91
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Nat Struct Mol Biol (2010) 1.80
The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development (2002) 1.77
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol (2007) 1.72
The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. Dev Cell (2006) 1.67
Biallelic genome modification in F(0) Xenopus tropicalis embryos using the CRISPR/Cas system. Genesis (2013) 1.65
A dual binding mode for RhoGTPases in plexin signalling. PLoS Biol (2011) 1.63
Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Development (2006) 1.60
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science (2011) 1.59
TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development (2004) 1.56
Microarray optimizations: increasing spot accuracy and automated identification of true microarray signals. Nucleic Acids Res (2002) 1.54
Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. Dev Cell (2012) 1.53
Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors. J Mol Biol (2009) 1.53
Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling. Dev Cell (2011) 1.50
Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice. Development (2007) 1.49
The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A (2011) 1.40
Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. Genes Dev (2005) 1.36
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol (2011) 1.33
Premature luteinization and cumulus cell defects in ovarian-specific Smad4 knockout mice. Mol Endocrinol (2006) 1.33
Crystal structure and carbohydrate analysis of Nipah virus attachment glycoprotein: a template for antiviral and vaccine design. J Virol (2008) 1.32
TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev (2007) 1.32
Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol (2006) 1.32
T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. Immunity (2004) 1.31
Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling. Structure (2009) 1.29
Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP. Nat Struct Mol Biol (2009) 1.29
Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing. Genome Res (2008) 1.28
Xenopus as a model system to study transcriptional regulatory networks. Proc Natl Acad Sci U S A (2005) 1.28
BMP4 substitutes for loss of BMP7 during kidney development. Dev Biol (2005) 1.27
Protein tyrosine phosphatases: structure-function relationships. FEBS J (2008) 1.27
An expanding job description for Blimp-1/PRDM1. Curr Opin Genet Dev (2009) 1.27
Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo. Development (2004) 1.24
Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1. Nat Struct Mol Biol (2011) 1.21
Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway. Glycobiology (2006) 1.18
Generation and analysis of a mouse line harboring GFP in the Eomes/Tbr2 locus. Genesis (2009) 1.14
Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism. Development (2006) 1.13
BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. Genes Dev (2008) 1.12
Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis. J Am Chem Soc (2012) 1.12
BMP4 activation and secretion are negatively regulated by an intracellular gremlin-BMP4 interaction. J Biol Chem (2006) 1.07
The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling. Genes Dev (2002) 1.07
Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling. Mech Dev (2003) 1.07
Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions. J Mol Biol (2009) 1.05
Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning. Dev Biol (2004) 1.04
Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis. Am J Pathol (2011) 1.03
DM loss in k haplotype mice reveals isotype-specific chaperone requirements. J Immunol (2003) 1.03
Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected] Proc Natl Acad Sci U S A (2011) 1.02
Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis. Mech Dev (2006) 1.01
Atomic-resolution monitoring of protein maturation in live human cells by NMR. Nat Chem Biol (2013) 1.01
Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol (2010) 1.00
Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos. PLoS One (2009) 1.00
Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. Mol Cell Biol (2009) 1.00
Structurally encoded intraclass differences in EphA clusters drive distinct cell responses. Nat Struct Mol Biol (2013) 1.00
Control of early anterior-posterior patterning in the mouse embryo by TGF-beta signalling. Philos Trans R Soc Lond B Biol Sci (2003) 0.99
Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes. Dev Biol (2005) 0.99
The crystal structure of ORF-9b, a lipid binding protein from the SARS coronavirus. Structure (2006) 0.98
Finding partners: how BMPs select their targets. Dev Dyn (2009) 0.97
The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development (2009) 0.97
Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol (2009) 0.95
Automation of large scale transient protein expression in mammalian cells. J Struct Biol (2011) 0.95
Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis. Development (2003) 0.94
Regulatory targets for transcription factor AP2 in Xenopus embryos. Dev Growth Differ (2005) 0.94
The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. Genes Dev (2013) 0.94
Highly efficient transgene-independent recombination directed by a maternally derived SOX2CRE transgene. Genesis (2003) 0.94
Chick PTPsigma regulates the targeting of retinal axons within the optic tectum. J Neurosci (2002) 0.92
Loss of invariant chain protects nonobese diabetic mice against type 1 diabetes. J Immunol (2006) 0.89
Microarray-based identification of VegT targets in Xenopus. Mech Dev (2005) 0.89
Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney. Mech Dev (2002) 0.89
Global analysis of RAR-responsive genes in the Xenopus neurula using cDNA microarrays. Dev Dyn (2005) 0.88
Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements. Mech Dev (2004) 0.88
DM peptide-editing function leads to immunodominance in CD4 T cell responses in vivo. J Immunol (2005) 0.88
The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice. PLoS One (2013) 0.87
Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes. J Leukoc Biol (2012) 0.87
Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev (2012) 0.87
Isoform-specific binding of the tyrosine phosphatase PTPsigma to a ligand in developing muscle. Mol Cell Neurosci (2003) 0.87
Identification of neural genes using Xenopus DNA microarrays. Dev Dyn (2005) 0.87