Published in Genes Dev on July 01, 2003
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling. Proc Natl Acad Sci U S A (2008) 2.99
Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol (2009) 2.86
Pluripotency factors regulate definitive endoderm specification through eomesodermin. Genes Dev (2011) 2.22
Nodal morphogens. Cold Spring Harb Perspect Biol (2009) 2.09
Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Mol Cell Biol (2006) 1.82
Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol. Hepatology (2012) 1.64
The molecular genetics of holoprosencephaly. Am J Med Genet C Semin Med Genet (2010) 1.57
Vertebrate intestinal endoderm development. Dev Dyn (2011) 1.41
Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. Genes Dev (2005) 1.36
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics (2008) 1.35
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol (2011) 1.33
GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression. Cell Adh Migr (2011) 1.31
A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. J Cell Sci (2011) 1.30
Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain. Dev Biol (2008) 1.30
Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly. Mol Genet Metab (2009) 1.21
Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions. PLoS Genet (2011) 1.20
SMAD2 is essential for TGF beta-mediated Th17 cell generation. J Biol Chem (2010) 1.18
Smad2 positively regulates the generation of Th17 cells. J Biol Chem (2010) 1.17
A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. Dev Biol (2009) 1.16
Nodal signaling via an autocrine pathway promotes proliferation of mouse spermatogonial stem/progenitor cells through Smad2/3 and Oct-4 activation. Stem Cells (2009) 1.15
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic Biol Med (2007) 1.13
Genomic chart guiding embryonic stem cell cardiopoiesis. Genome Biol (2008) 1.13
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation. EMBO J (2013) 1.11
Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans. Am J Hum Genet (2007) 1.06
Patterning and plasticity in development of the respiratory lineage. Dev Dyn (2010) 1.05
Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction. J Cell Biol (2008) 1.01
Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice. PLoS Genet (2012) 0.98
Nodal and lefty signaling regulates the growth of pancreatic cells. Dev Dyn (2008) 0.96
Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation. Development (2013) 0.96
Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol (2009) 0.95
Orchestrating liver development. Development (2015) 0.94
The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities. Genes Dev (2011) 0.90
Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord. Mech Dev (2009) 0.90
Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin. EMBO Rep (2012) 0.89
Generating β cells from stem cells-the story so far. Cold Spring Harb Perspect Med (2012) 0.88
Developmental effects of tobacco smoke exposure during human embryonic stem cell differentiation are mediated through the transforming growth factor-β superfamily member, Nodal. Differentiation (2012) 0.86
Forming and interpreting gradients in the early Xenopus embryo. Cold Spring Harb Perspect Biol (2009) 0.86
Correct patterning of the primitive streak requires the anterior visceral endoderm. PLoS One (2011) 0.86
BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning. Hum Mol Genet (2010) 0.84
Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells. Int J Dev Biol (2010) 0.83
A gutsy task: generating intestinal tissue from human pluripotent stem cells. Dig Dis Sci (2013) 0.83
Mice develop normally in the absence of Smad4 nucleocytoplasmic shuttling. Biochem J (2007) 0.82
Left-right asymmetry in the sea urchin embryo: BMP and the asymmetrical origins of the adult. PLoS Biol (2012) 0.82
Differential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development in the embryo. Philos Trans R Soc Lond B Biol Sci (2014) 0.81
Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol (2012) 0.81
Human embryonic stem cells and lung regeneration. Br J Pharmacol (2008) 0.80
Involvement of histone acetylation of Sox17 and Foxa2 promoters during mouse definitive endoderm differentiation revealed by microRNA profiling. PLoS One (2011) 0.80
Stem cell approaches for the treatment of type 1 diabetes mellitus. Transl Res (2010) 0.80
Understanding kidney morphogenesis to guide renal tissue regeneration. Nat Rev Nephrol (2016) 0.80
Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J (2015) 0.79
Meteorin regulates mesendoderm development by enhancing nodal expression. PLoS One (2014) 0.79
Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development. Genes Dev (2015) 0.79
NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos. Dis Model Mech (2012) 0.78
Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification. Sci Rep (2016) 0.78
The Dynamics of Morphogenesis in the Early Mouse Embryo. Cold Spring Harb Perspect Biol (2014) 0.78
Signaling Pathways and Gene Regulatory Networks in Cardiomyocyte Differentiation. Tissue Eng Part B Rev (2015) 0.77
Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration. Dev Biol (2014) 0.77
Early patterning in a chondrichthyan model, the small spotted dogfish: towards the gnathostome ancestral state. J Anat (2012) 0.77
Disrupting Foxh1-Groucho interaction reveals robustness of nodal-based embryonic patterning. Mech Dev (2014) 0.77
Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation. Dev Biol (2013) 0.77
Differential expression of natural antisense transcripts during liver development in embryonic mice. Biomed Rep (2014) 0.76
Endothelium-derived essential signals involved in pancreas organogenesis. World J Exp Med (2015) 0.76
The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo. Mol Cell Biol (2013) 0.76
Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis. Biol Open (2012) 0.76
Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet (2016) 0.75
Finding degrees of separation: experimental approaches for astroglial and oligodendroglial cell isolation and genetic targeting. J Neurosci Methods (2014) 0.75
Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo. Development (2017) 0.75
Spatiotemporal regulation of fibroblast growth factor signal blocking for endoderm formation in Xenopus laevis. Exp Mol Med (2008) 0.75
ProNodal acts via FGFR3 to govern duration of Shh expression in the prechordal mesoderm. Development (2015) 0.75
A regulatory network controls nephrocan expression and midgut patterning. Development (2014) 0.75
Endoderm complexity in the mouse gastrula is revealed through the expression of spink3. Biores Open Access (2014) 0.75
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
TGFbeta signaling in growth control, cancer, and heritable disorders. Cell (2000) 12.38
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc Natl Acad Sci U S A (1997) 7.42
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell (1993) 7.41
The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development (1995) 4.65
Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4. Science (2002) 4.33
HNF-3 beta is essential for node and notochord formation in mouse development. Cell (1994) 4.08
Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development (1995) 3.90
Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice. Genesis (2000) 3.74
The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell (1994) 3.71
Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol Cell Biol (1999) 3.55
Axis development and early asymmetry in mammals. Cell (1999) 3.34
Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev Cell (2001) 3.30
nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development (1997) 3.15
A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development (1994) 3.12
Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech Dev (1997) 2.83
The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature (2000) 2.78
Nodal signalling in the epiblast patterns the early mouse embryo. Nature (2001) 2.65
Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo. Cell (1998) 2.60
Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors. Development (1998) 2.59
Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature (1993) 2.45
Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks. Dev Cell (2002) 2.24
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development (2000) 2.22
Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr Biol (1996) 2.22
Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos. Development (1991) 2.09
Genetic dissection of nodal function in patterning the mouse embryo. Development (2001) 2.07
Endodermal Nodal-related signals and mesoderm induction in Xenopus. Development (2000) 1.97
The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development (1998) 1.85
Morphogenesis of the murine node and notochordal plate. Dev Dyn (1994) 1.84
Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell (1992) 1.83
Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol Cell (2000) 1.78
Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2. Mol Cell (2001) 1.77
The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development (2002) 1.77
Nodal signaling in early vertebrate embryos: themes and variations. Dev Cell (2001) 1.74
The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation. Cell (1993) 1.70
From fertilization to gastrulation: axis formation in the mouse embryo. Curr Opin Genet Dev (2001) 1.66
Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Gene Expr Patterns (2002) 1.61
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell (1998) 1.61
The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. Genes Dev (2001) 1.54
Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elements. Genes Dev (1999) 1.52
FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse. Genes Dev (2001) 1.47
Initial patterning of the central nervous system: how many organizers? Nat Rev Neurosci (2001) 1.46
Regulation of left-right patterning in mice by growth/differentiation factor-1. Nat Genet (2000) 1.43
Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis. Proc Natl Acad Sci U S A (1999) 1.41
Cre expression in primary spermatocytes: a tool for genetic engineering of the germ line. Mol Reprod Dev (1998) 1.39
Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants. Development (1994) 1.39
Visceral endoderm mediates forebrain development by suppressing posteriorizing signals. Dev Biol (2000) 1.38
Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements. Genes Cells (1996) 1.37
Distinct enhancer elements control Hex expression during gastrulation and early organogenesis. Dev Biol (2001) 1.31
Formation of the definitive endoderm in mouse is a Smad2-dependent process. Development (2000) 1.31
Nodal signaling patterns the organizer. Development (2000) 1.22
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages. Nature (2001) 1.18
The zinc finger gene Xblimp1 controls anterior endomesodermal cell fate in Spemann's organizer. EMBO J (1999) 1.08
XSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos. EMBO J (1997) 1.07
Mesendoderm induction and reversal of left-right pattern by mouse Gdf1, a Vg1-related gene. Dev Biol (2000) 1.06
Lim1 is required in both primitive streak-derived tissues and visceral endoderm for head formation in the mouse. Development (1999) 1.05
A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis. Mech Dev (1998) 1.04
Impact of node ablation on the morphogenesis of the body axis and the lateral asymmetry of the mouse embryo during early organogenesis. Dev Biol (1999) 1.04
Neural induction and patterning in the mouse in the absence of the node and its derivatives. Dev Biol (1999) 1.00
Cell autonomous commitment to an endodermal fate and behaviour by activation of Nodal signalling. Development (2001) 1.00
Fate mapping the mouse embryo. Int J Dev Biol (1999) 0.97
Maintenance of the specification of the anterior definitive endoderm and forebrain depends on the axial mesendoderm: a study using HNF3beta/Foxa2 conditional mutants. Dev Biol (2002) 0.93
The organizer of the gastrulating mouse embryo. Curr Top Dev Biol (1999) 0.82
Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell (2005) 4.91
SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci (2005) 4.48
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron (2003) 3.76
An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell (2007) 3.74
Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection. Science (2012) 3.39
Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol (2009) 2.86
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone. Genes Dev (2008) 2.33
Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo. Development (2004) 2.28
The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development (2005) 2.23
Pluripotency factors regulate definitive endoderm specification through eomesodermin. Genes Dev (2011) 2.22
Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies. Stem Cell Res (2009) 2.10
Nodal activity in the node governs left-right asymmetry. Genes Dev (2002) 1.95
Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development (2008) 1.94
The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development (2002) 1.77
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol (2007) 1.72
The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. Dev Cell (2006) 1.67
TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development (2004) 1.56
Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. Dev Cell (2012) 1.53
Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors. Stem Cells (2011) 1.51
Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2. Development (2011) 1.47
Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage. Stem Cells Dev (2007) 1.41
The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A (2011) 1.40
p38MAPK controls expression of multiple cell cycle inhibitors and islet proliferation with advancing age. Dev Cell (2009) 1.40
Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. Genes Dev (2005) 1.36
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol (2011) 1.33
Premature luteinization and cumulus cell defects in ovarian-specific Smad4 knockout mice. Mol Endocrinol (2006) 1.33
Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol (2006) 1.32
BMP4 substitutes for loss of BMP7 during kidney development. Dev Biol (2005) 1.27
An expanding job description for Blimp-1/PRDM1. Curr Opin Genet Dev (2009) 1.27
Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover. PLoS Biol (2007) 1.24
Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo. Development (2004) 1.24
Generation and analysis of a mouse line harboring GFP in the Eomes/Tbr2 locus. Genesis (2009) 1.14
BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. Genes Dev (2008) 1.12
AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome. Neurobiol Dis (2011) 1.09
Activin and BMP4 synergistically promote formation of definitive endoderm in human embryonic stem cells. Stem Cells (2012) 1.09
BMP4 activation and secretion are negatively regulated by an intracellular gremlin-BMP4 interaction. J Biol Chem (2006) 1.07
The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol (2010) 1.06
Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3. Dev Biol (2008) 1.06
Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning. Dev Biol (2004) 1.04
Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis. Am J Pathol (2011) 1.03
DM loss in k haplotype mice reveals isotype-specific chaperone requirements. J Immunol (2003) 1.03
Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected] Proc Natl Acad Sci U S A (2011) 1.02
Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. Mol Cell Biol (2009) 1.00
Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development. Dev Dyn (2009) 1.00
Control of early anterior-posterior patterning in the mouse embryo by TGF-beta signalling. Philos Trans R Soc Lond B Biol Sci (2003) 0.99
Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Dev Biol (2007) 0.99
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells. PLoS One (2009) 0.99
Static respiratory cilia associated with mutations in Dnahc11/DNAH11: a mouse model of PCD. Hum Mutat (2011) 0.97
Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol (2009) 0.95
The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. Genes Dev (2013) 0.94
Highly efficient transgene-independent recombination directed by a maternally derived SOX2CRE transgene. Genesis (2003) 0.94
Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney. Mech Dev (2002) 0.89
Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements. Mech Dev (2004) 0.88
Repressed by a NuRD. Nat Cell Biol (2006) 0.88
The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice. PLoS One (2013) 0.87
Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes. J Leukoc Biol (2012) 0.87
Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev (2012) 0.87
No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc(delta716) knockout mice. Cancer Res (2002) 0.85
Targeted insertion of an IRES Cre into the Hnf4alpha locus: Cre-mediated recombination in the liver, kidney, and gut epithelium. Genesis (2004) 0.83
Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow. BMC Dev Biol (2010) 0.83
Guards at the gate to embryonic stem cell differentiation. Cell (2013) 0.82
Mice develop normally in the absence of Smad4 nucleocytoplasmic shuttling. Biochem J (2007) 0.82
Three-dimensional extracellular matrix stimulates gastrulation-like events in human embryoid bodies. Stem Cells Dev (2006) 0.82
Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities and corepressor interactions. Mol Cell Biol (2012) 0.78
The SMAD2/3 corepressor SNON maintains pluripotency through selective repression of mesendodermal genes in human ES cells. Genes Dev (2012) 0.78
Mutated in colorectal cancer (Mcc), a candidate tumor suppressor, is dynamically expressed during mouse embryogenesis. Dev Dyn (2011) 0.78
The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo. Mol Cell Biol (2013) 0.76
One PRDM is not enough for germ cell development. Nat Genet (2008) 0.76