Published in J Virol on April 30, 2008
A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans. Hum Mol Genet (2010) 1.60
Dietary cholesterol modulates pathogen blocking by Wolbachia. PLoS Pathog (2013) 1.52
Low pH-dependent hepatitis C virus membrane fusion depends on E2 integrity, target lipid composition, and density of virus particles. J Biol Chem (2009) 1.14
Involvement of ceramide in the propagation of Japanese encephalitis virus. J Virol (2010) 1.11
Differential cholesterol binding by class II fusion proteins determines membrane fusion properties. J Virol (2008) 1.06
Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism. J Virol (2012) 1.03
Cholesterol-rich microdomains as docking platforms for respiratory syncytial virus in normal human bronchial epithelial cells. J Virol (2011) 1.02
Inhibition of sterol biosynthesis reduces tombusvirus replication in yeast and plants. J Virol (2009) 1.00
Coupling of replication and assembly in flaviviruses. Curr Opin Virol (2014) 0.99
FUSE binding protein 1 interacts with untranslated regions of Japanese encephalitis virus RNA and negatively regulates viral replication. J Virol (2011) 0.96
Early dengue virus protein synthesis induces extensive rearrangement of the endoplasmic reticulum independent of the UPR and SREBP-2 pathway. PLoS One (2012) 0.95
Japanese encephalitis virus enters rat neuroblastoma cells via a pH-dependent, dynamin and caveola-mediated endocytosis pathway. J Virol (2012) 0.95
Competition for amino acids between Wolbachia and the mosquito host, Aedes aegypti. Microb Ecol (2013) 0.95
Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells. PLoS One (2009) 0.93
A bacteriophage endolysin that eliminates intracellular streptococci. Elife (2016) 0.92
Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses. PLoS Pathog (2013) 0.92
Targeting host factors to treat West Nile and dengue viral infections. Viruses (2014) 0.92
Co-opted oxysterol-binding ORP and VAP proteins channel sterols to RNA virus replication sites via membrane contact sites. PLoS Pathog (2014) 0.91
Evolutionary responses to a constructed niche: ancient Mesoamericans as a model of gene-culture coevolution. PLoS One (2012) 0.91
Suppressing dengue-2 infection by chemical inhibition of Aedes aegypti host factors. PLoS Negl Trop Dis (2014) 0.90
Development and Applications of VSV Vectors Based on Cell Tropism. Front Microbiol (2012) 0.90
Japanese encephalitis virus infects porcine kidney epithelial PK15 cells via clathrin- and cholesterol-dependent endocytosis. Virol J (2013) 0.86
Targeting host lipid synthesis and metabolism to inhibit dengue and hepatitis C viruses. Antiviral Res (2015) 0.84
Caveolin-1 in lipid rafts interacts with dengue virus NS3 during polyprotein processing and replication in HMEC-1 cells. PLoS One (2014) 0.82
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction. Biochimie (2012) 0.82
Function of membrane rafts in viral lifecycles and host cellular response. Biochem Res Int (2011) 0.82
Liposome-mediated delivery of iminosugars enhances efficacy against dengue virus in vivo. Antimicrob Agents Chemother (2012) 0.82
Cholesterol dependence of collagen and echovirus 1 trafficking along the novel α2β1 integrin internalization pathway. PLoS One (2013) 0.82
Tetherin has negligible activity in restricting hepatitis C virus in hepatocytes. Innate Immun (2011) 0.81
Identification of Host Cell Factors Associated with Astrovirus Replication in Caco-2 Cells. J Virol (2015) 0.81
Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation. Viruses (2016) 0.79
Human astrocytic cells support persistent coxsackievirus B3 infection. J Virol (2013) 0.79
Detection of convergent genome-wide signals of adaptation to tropical forests in humans. PLoS One (2015) 0.79
Flavivirus modulation of cellular metabolism. Curr Opin Virol (2016) 0.78
Flaviviruses are sensitive to inhibition of thymidine synthesis pathways. J Virol (2013) 0.78
Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. J Gen Virol (2015) 0.77
Lower Low-Density Lipoprotein Cholesterol Levels Are Associated with Severe Dengue Outcome. PLoS Negl Trop Dis (2015) 0.76
DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target. PLoS Pathog (2017) 0.75
The fluid mosaic model of the structure of cell membranes. Science (1972) 37.43
Lipid rafts and signal transduction. Nat Rev Mol Cell Biol (2000) 25.87
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell (1992) 17.81
The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature (1995) 12.25
Structure of the dengue virus envelope protein after membrane fusion. Nature (2004) 7.97
Lipid sorting in epithelial cells. Biochemistry (1988) 7.64
The multiple faces of caveolae. Nat Rev Mol Cell Biol (2007) 6.85
Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol (2006) 6.85
The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH. Cell (2001) 5.65
Neurotransmitter synthesis by neuroblastoma clones (neuroblast differentiation-cell culture-choline acetyltransferase-acetylcholinesterase-tyrosine hydroxylase-axons-dendrites). Proc Natl Acad Sci U S A (1972) 5.30
Cholesterol and the cell membrane. Biochim Biophys Acta (1985) 4.87
Use of cyclodextrins for manipulating cellular cholesterol content. J Lipid Res (1997) 4.44
Molecular biology of flaviviruses. Adv Virus Res (2003) 4.39
VIP21/caveolin is a cholesterol-binding protein. Proc Natl Acad Sci U S A (1995) 3.97
Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication. Virology (1996) 3.60
Cholesterol interactions with phospholipids in membranes. Prog Lipid Res (2002) 3.34
Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets. EMBO J (2002) 3.33
Viral RNA replication in association with cellular membranes. Curr Top Microbiol Immunol (2005) 3.18
Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft. J Virol (2004) 2.89
Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2. J Virol (2003) 2.86
Sorting GPI-anchored proteins. Nat Rev Mol Cell Biol (2004) 2.77
Virus entry, assembly, budding, and membrane rafts. Microbiol Mol Biol Rev (2003) 2.68
Pathogens: raft hijackers. Nat Rev Immunol (2003) 2.63
Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins. Virology (2002) 2.55
Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells. J Virol (2002) 2.49
Bc1-2 protects mice against fatal alphavirus encephalitis. Proc Natl Acad Sci U S A (1996) 2.31
The cholesterol requirement for sindbis virus entry and exit and characterization of a spike protein region involved in cholesterol dependence. J Virol (1999) 2.28
Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. Virology (2004) 2.28
Cholesterol manipulation by West Nile virus perturbs the cellular immune response. Cell Host Microbe (2007) 2.14
RNA-protein interactions: involvement of NS3, NS5, and 3' noncoding regions of Japanese encephalitis virus genomic RNA. J Virol (1997) 2.12
Membrane fusion activity of tick-borne encephalitis virus and recombinant subviral particles in a liposomal model system. Virology (2000) 2.09
Study of Dengue virus infection in SCID mice engrafted with human K562 cells. J Virol (1998) 2.03
Non-bilayer lipids and biological fusion intermediates. Chem Phys Lipids (1996) 1.95
Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry. J Virol (2003) 1.92
Lipid rafts and plasma membrane microorganization: insights from Ras. Trends Cell Biol (2004) 1.92
A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance. J Cell Biol (2001) 1.92
Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies. Mol Biol Cell (2005) 1.86
Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells. J Virol (2005) 1.83
Role for human immunodeficiency virus type 1 membrane cholesterol in viral internalization. J Virol (2002) 1.81
Accumulation of caveolin in the endoplasmic reticulum redirects the protein to lipid storage droplets. J Cell Biol (2001) 1.81
Persistence of Japanese encephalitis virus is associated with abnormal expression of the nonstructural protein NS1 in host cells. Virology (1996) 1.69
Low-pH-dependent fusion of Sindbis virus with receptor-free cholesterol- and sphingolipid-containing liposomes. J Virol (1999) 1.69
Do lipid rafts mediate virus assembly and pseudotyping? J Gen Virol (2003) 1.67
Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell. J Cell Biol (2001) 1.67
Drug solubilizers to aid pharmacologists: amorphous cyclodextrin derivatives. Life Sci (1988) 1.61
Kunjin RNA replication and applications of Kunjin replicons. Adv Virus Res (2003) 1.56
Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection. J Virol (2005) 1.53
Biochemical characterization of rotavirus receptors in MA104 cells. J Virol (2000) 1.52
Influence of lipid composition on physical properties and peg-mediated fusion of curved and uncurved model membrane vesicles: "nature's own" fusogenic lipid bilayer. Biochemistry (2001) 1.51
Role for influenza virus envelope cholesterol in virus entry and infection. J Virol (2003) 1.47
Characterization of rotavirus cell entry. J Virol (2004) 1.46
Specific roles for lipids in virus fusion and exit. Examples from the alphaviruses. Subcell Biochem (2000) 1.46
Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein. Virology (1998) 1.46
pH-dependent fusion between the flavivirus West Nile and liposomal model membranes. J Gen Virol (1986) 1.45
Involvement of lipids in different steps of the flavivirus fusion mechanism. J Virol (2003) 1.42
Caveolin, cholesterol, and lipid bodies. Semin Cell Dev Biol (2005) 1.41
Flavivirus structure and membrane fusion. Adv Virus Res (2003) 1.39
Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virus. J Virol (2002) 1.37
Modulation of entry of enveloped viruses by cholesterol and sphingolipids (Review). Mol Membr Biol (2003) 1.30
Caveolins and cellular cholesterol balance. Traffic (2000) 1.29
Long-range order in biomembranes. Adv Lipid Res (1977) 1.25
Sterols and sphingolipids strongly affect the growth of fusion pores induced by the hemagglutinin of influenza virus. Biochemistry (2000) 1.16
Palmitoylation of the murine leukemia virus envelope protein is critical for lipid raft association and surface expression. J Virol (2002) 1.16
Lipid rafts and the initiation of T cell receptor signaling. Semin Immunol (2005) 1.14
Blood lipids of patients with chronic hepatitis: differences related to viral etiology. Clin Chim Acta (1997) 1.14
Requirements for CEACAMs and cholesterol during murine coronavirus cell entry. J Virol (2004) 1.12
Association of hypocholesterolaemia with hepatitis C virus infection in HIV-infected people. HIV Med (2004) 1.10
Localization and functions of Japanese encephalitis virus nonstructural proteins NS3 and NS5 for viral RNA synthesis in the infected cells. Microbiol Immunol (1993) 1.00
Annexin II is required for apical transport in polarized epithelial cells. J Biol Chem (2003) 0.99
Manipulation of cell surface macromolecules by flaviviruses. Adv Virus Res (2003) 0.98
Cholesterol stabilizes hemifused phospholipid bilayer vesicles. Biochim Biophys Acta (2001) 0.91
Changes in free cholesterol content, measured by filipin fluorescence and flow cytometry, correlate with changes in cholesterol biosynthesis in THP-1 macrophages. Cytometry (1995) 0.82
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability. Cell (2002) 3.72
CLEC5A is critical for dengue-virus-induced lethal disease. Nature (2008) 2.79
Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response. J Virol (2002) 2.41
Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-kappaB activation. Microbes Infect (2005) 2.11
Flavivirus infection activates the XBP1 pathway of the unfolded protein response to cope with endoplasmic reticulum stress. J Virol (2006) 2.02
Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism. J Virol (2006) 2.02
Blocking of the alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection. J Virol (2004) 2.01
A Japanese encephalitis virus vaccine candidate strain is attenuated by decreasing its interferon antagonistic ability. Vaccine (2009) 1.81
Antiviral effects of an iminosugar derivative on flavivirus infections. J Virol (2002) 1.80
Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus. J Immunol (2006) 1.70
Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell. J Immunol (2005) 1.63
Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection. J Virol (2005) 1.53
Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells by down-regulating endothelial nitric oxide synthase expression and intracellular calcium levels. Crit Care Med (2005) 1.47
Dengue virus targets the adaptor protein MITA to subvert host innate immunity. PLoS Pathog (2012) 1.44
Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection. J Immunol (2009) 1.41
A salivary gland adenocarcinoma mimicking a microcystic adnexal carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 1.38
Dengue virus induces expression of CXC chemokine ligand 10/IFN-gamma-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate. J Immunol (2006) 1.38
Role of pancreatic cancer-derived exosomes in salivary biomarker development. J Biol Chem (2013) 1.37
CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages. Blood (2012) 1.22
The interferon stimulator mitochondrial antiviral signaling protein facilitates cell death by disrupting the mitochondrial membrane potential and by activating caspases. J Virol (2009) 1.19
SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis. J Cell Biol (2008) 1.14
Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memory. J Neurosci (2007) 1.13
Autophagy is involved in the early step of Japanese encephalitis virus infection. Microbes Infect (2011) 1.12
The cellular antiviral protein viperin is attenuated by proteasome-mediated protein degradation in Japanese encephalitis virus-infected cells. J Virol (2008) 1.10
Evaluation of protective efficacy and immune mechanisms of using a non-structural protein NS1 in DNA vaccine against dengue 2 virus in mice. Vaccine (2003) 1.10
Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay. Antimicrob Agents Chemother (2010) 1.09
Calcifying odontogenic cyst with odontogenic keratocyst: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 1.04
Identification of Tbr-1/CASK complex target genes in neurons. J Neurochem (2004) 1.04
Restriction of vaccinia virus replication by a ced-3 and ced-4-dependent pathway in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2006) 1.04
Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinases. Toxicol Appl Pharmacol (2009) 1.03
Blocking double-stranded RNA-activated protein kinase PKR by Japanese encephalitis virus nonstructural protein 2A. J Virol (2012) 1.03
MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation. Nucleic Acids Res (2013) 1.01
Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein. J Gen Virol (2003) 1.00
CLEC5A regulates Japanese encephalitis virus-induced neuroinflammation and lethality. PLoS Pathog (2012) 1.00
Design of microarray probes for virus identification and detection of emerging viruses at the genus level. BMC Bioinformatics (2006) 1.00
Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage. J Agric Food Chem (2010) 1.00
Structural variation in human apolipoprotein E3 and E4: secondary structure, tertiary structure, and size distribution. Biophys J (2004) 0.98
Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFkappaB. Chem Biol Interact (2009) 0.98
Utilizing liver-specific microRNA-122 to modulate replication of dengue virus replicon. Biochem Biophys Res Commun (2010) 0.96
Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway. Neuro Oncol (2012) 0.96
FUSE binding protein 1 interacts with untranslated regions of Japanese encephalitis virus RNA and negatively regulates viral replication. J Virol (2011) 0.96
Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model. Biochem Biophys Res Commun (2009) 0.95
Vimentin binding is critical for infection by the virulent strain of Japanese encephalitis virus. Cell Microbiol (2011) 0.95
Signal-transducing mechanisms of ketamine-caused inhibition of interleukin-1 beta gene expression in lipopolysaccharide-stimulated murine macrophage-like Raw 264.7 cells. Toxicol Appl Pharmacol (2009) 0.94
Effects of provider patient volume and comorbidity on clinical and economic outcomes for total knee arthroplasty: a population-based study. J Arthroplasty (2010) 0.93
Development of a humanized antibody with high therapeutic potential against dengue virus type 2. PLoS Negl Trop Dis (2012) 0.93
Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis. Chembiochem (2006) 0.93
Neurovirulent flavivirus can be attenuated in mice by incorporation of neuron-specific microRNA recognition elements into viral genome. Vaccine (2011) 0.93
The tyrosine kinase Syk differentially regulates Toll-like receptor signaling downstream of the adaptor molecules TRAF6 and TRAF3. Sci Signal (2013) 0.91
Replication-incompetent virions of Japanese encephalitis virus trigger neuronal cell death by oxidative stress in a culture system. J Gen Virol (2004) 0.91
Nitric oxide induces osteoblast apoptosis through the de novo synthesis of Bax protein. J Orthop Res (2002) 0.91
Effects of minocycline on Fas-mediated fulminant hepatitis in mice. Br J Pharmacol (2005) 0.91
Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions. Evid Based Complement Alternat Med (2013) 0.90
GATA-3 transduces survival signals in osteoblasts through upregulation of bcl-x(L) gene expression. J Bone Miner Res (2010) 0.89
Preventive effects of taurine on development of hepatic steatosis induced by a high-fat/cholesterol dietary habit. J Agric Food Chem (2010) 0.88
Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner. J Gen Virol (2008) 0.87
Synthesis and characterization of amphiphatic carboxymethyl-hexanoyl chitosan hydrogel: water-retention ability and drug encapsulation. Langmuir (2006) 0.86
Antiobesity and hypolipidemic effects of polyphenol-rich longan (Dimocarpus longans Lour.) flower water extract in hypercaloric-dietary rats. J Agric Food Chem (2010) 0.86
Carvedilol, a new antioxidative beta-blocker, blocks in vitro human peripheral blood T cell activation by downregulating NF-kappaB activity. Cardiovasc Res (2003) 0.85
Nitric oxide protects osteoblasts from oxidative stress-induced apoptotic insults via a mitochondria-dependent mechanism. J Orthop Res (2006) 0.85
Patients with inhibitory and neutralizing auto-antibodies to interferon-γ resemble the sporadic adult-onset phenotype of Mendelian Susceptibility to Mycobacterial Disease (MSMD) lacking Bacille Calmette-Guerin (BCG)-induced diseases. Immunobiology (2012) 0.84
Molecular mechanisms of propofol-involved suppression of no biosynthesis and inducible iNOS gene expression in LPS-stimulated macrophage-like raw 264.7 cells. Shock (2010) 0.84
Plexin-B1 and semaphorin 4D cooperate to promote perineural invasion in a RhoA/ROK-dependent manner. Am J Pathol (2012) 0.84
Mitf induction by RANKL is critical for osteoclastogenesis. Mol Biol Cell (2010) 0.84
Localized intermittent delivery of simvastatin hydroxyacid stimulates bone formation in rats. J Periodontol (2008) 0.84
Hydroxychloroquine-inhibited dengue virus is associated with host defense machinery. J Interferon Cytokine Res (2014) 0.84
Ubiquitin-specific protease 13 regulates IFN signaling by stabilizing STAT1. J Immunol (2013) 0.83
Propofol suppresses macrophage functions and modulates mitochondrial membrane potential and cellular adenosine triphosphate synthesis. Anesthesiology (2003) 0.83
Distribution, clinical features and treatment in Taiwanese patients with symptomatic primary immunodeficiency diseases (PIDs) in a nationwide population-based study during 1985-2010. Immunobiology (2011) 0.83
Dengue virus serotype 2 blocks extracellular signal-regulated kinase and nuclear factor-κB activation to downregulate cytokine production. PLoS One (2012) 0.83
In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models. Antimicrob Agents Chemother (2010) 0.81