PubRank

Charles A Lesburg

Author PubWeight™ 8.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability. Protein Eng Des Sel 2008 0.90
2 Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides. Bioorg Med Chem Lett 2010 0.90
3 Evaluation of in vitro PXR-based assays and in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR. Biochem Pharmacol 2010 0.88
4 A novel class of highly potent irreversible hepatitis C virus NS5B polymerase inhibitors. J Med Chem 2012 0.82
5 Synthesis of new 4,5-dihydrofuranoindoles and their evaluation as HCV NS5B polymerase inhibitors. Org Lett 2012 0.82
6 Thermodynamics of nucleotide and inhibitor binding to wild-type and ispinesib-resistant forms of human kinesin spindle protein. Biochemistry 2009 0.81
7 Structure-activity relationship (SAR) development and discovery of potent indole-based inhibitors of the hepatitis C virus (HCV) NS5B polymerase. J Med Chem 2012 0.80
8 Crystallization of an apo form of human arginase: using all the tools in the toolbox simultaneously. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.79
9 I. Novel HCV NS5B polymerase inhibitors: discovery of indole 2-carboxylic acids with C3-heterocycles. Bioorg Med Chem Lett 2011 0.77
10 Discovery of an irreversible HCV NS5B polymerase inhibitor. Bioorg Med Chem Lett 2013 0.76
11 II. Novel HCV NS5B polymerase inhibitors: discovery of indole C2 acyl sulfonamides. Bioorg Med Chem Lett 2011 0.75