Published in J Biol Chem on May 05, 2008
PCSK9 is a critical regulator of the innate immune response and septic shock outcome. Sci Transl Med (2014) 2.33
Role of plasma phospholipid transfer protein in lipid and lipoprotein metabolism. Biochim Biophys Acta (2011) 1.01
Phospholipid transfer protein in human plasma associates with proteins linked to immunity and inflammation. Biochemistry (2010) 0.96
The impact of phospholipid transfer protein (PLTP) on lipoprotein metabolism. Nutr Metab (Lond) (2012) 0.90
Plasma phospholipid transfer protein, cholesteryl ester transfer protein and lecithin:cholesterol acyltransferase in end-stage renal disease (ESRD). Nephrol Dial Transplant (2009) 0.89
PLTP regulates STAT3 and NFκB in differentiated THP1 cells and human monocyte-derived macrophages. Biochim Biophys Acta (2011) 0.85
Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals. Nutr Metab (Lond) (2014) 0.80
Quantitative lipopolysaccharide analysis using HPLC/MS/MS and its combination with the limulus amebocyte lysate assay. J Lipid Res (2015) 0.79
TLR4/IFNγ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models. Oncoimmunology (2015) 0.77
The binding capability of plasma phospholipid transfer protein, but not HDL pool size, is critical to repress LPS induced inflammation. Sci Rep (2016) 0.75
Effect of Phospholipid Transfer Protein on Cigarette Smoke Extract-Induced IL-8 Production in Human Pulmonary Epithelial Cells. Inflammation (2016) 0.75
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. Circulation (2012) 3.38
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. PLoS Med (2013) 2.96
The future of the TNM staging system in colorectal cancer: time for a debate? Lancet Oncol (2007) 2.94
Ceramide is a cardiotoxin in lipotoxic cardiomyopathy. J Lipid Res (2008) 2.88
Low preoperative cholesterol level is a risk factor of sepsis and poor clinical outcome in patients undergoing cardiac surgery with cardiopulmonary bypass. Crit Care Med (2014) 2.68
HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway. J Clin Invest (2006) 2.36
Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice. J Biol Chem (2004) 1.95
Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. Immunity (2012) 1.82
Increased atherosclerotic lesions in apoE mice with plasma phospholipid transfer protein overexpression. Arterioscler Thromb Vasc Biol (2003) 1.79
Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice. Biochim Biophys Acta (2005) 1.77
Plasma sphingomyelin and subclinical atherosclerosis: findings from the multi-ethnic study of atherosclerosis. Am J Epidemiol (2006) 1.73
Phospholipid transfer protein is regulated by liver X receptors in vivo. J Biol Chem (2002) 1.59
A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein. J Lipid Res (2004) 1.59
High serum cholesteryl ester transfer rates and small high-density lipoproteins are associated with young age in patients with acute myocardial infarction. J Am Coll Cardiol (2007) 1.56
Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL. Arterioscler Thromb Vasc Biol (2007) 1.53
How many nodes must be examined to accurately stage gastric carcinomas? Results from a population based study. Cancer (2002) 1.50
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis. J Biol Chem (2002) 1.50
Liver phospholipid transfer protein (PLTP) expression with a PLTP-null background promotes very low-density lipoprotein production in mice. Hepatology (2012) 1.49
Expression of the pregnane X receptor in mice antagonizes the cholic acid-mediated changes in plasma lipoprotein profile. Arterioscler Thromb Vasc Biol (2005) 1.49
Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta. J Biol Chem (2002) 1.48
Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization. Biochim Biophys Acta (2007) 1.47
A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers. J Lipid Res (2003) 1.44
Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells. Cancer Res (2004) 1.42
Quantification of liver fat content: comparison of triple-echo chemical shift gradient-echo imaging and in vivo proton MR spectroscopy. Radiology (2009) 1.40
Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells. J Biol Chem (2003) 1.36
Rapid, specific, and sensitive measurements of plasma sphingomyelin and phosphatidylcholine. J Lipid Res (2005) 1.36
Clinical value of mitochondrial mutations in colorectal cancer. J Clin Oncol (2005) 1.33
Common genetic variation of the cholesteryl ester transfer protein gene strongly predicts future cardiovascular death in patients with coronary artery disease. J Am Coll Cardiol (2003) 1.32
Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy. Cancer Res (2011) 1.32
Hydration biomarkers in free-living adults with different levels of habitual fluid consumption. Br J Nutr (2012) 1.31
The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis. J Lipid Res (2008) 1.29
Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation. Arterioscler Thromb Vasc Biol (2008) 1.28
Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants. J Biol Chem (2005) 1.27
Cytotoxic effects induced by oxidative stress in cultured mammalian cells and protection provided by Hsp27 expression. Methods (2004) 1.26
Intravoxel incoherent motion diffusion-weighted imaging in nonalcoholic fatty liver disease: a 3.0-T MR study. Radiology (2012) 1.25
C-reactive protein is an early predictor of septic complications after elective colorectal surgery. World J Surg (2010) 1.24
Macrophage sphingomyelin synthase 2 deficiency decreases atherosclerosis in mice. Circ Res (2009) 1.24
Scavenger receptor class B type I (SR-BI) is involved in vitamin E transport across the enterocyte. J Biol Chem (2005) 1.23
A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes. J Neurochem (2004) 1.23
Reducing plasma membrane sphingomyelin increases insulin sensitivity. Mol Cell Biol (2011) 1.20
Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease. Nutr Metab (Lond) (2006) 1.20
Effects of a high-fat diet on energy metabolism and ROS production in rat liver. J Hepatol (2010) 1.20
Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene (2004) 1.19
Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity. Sci Transl Med (2013) 1.16
Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice. Arterioscler Thromb Vasc Biol (2009) 1.16
SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. J Lipid Res (2007) 1.15
PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes. Liver Int (2011) 1.14
Association of plasma sphingomyelin levels and incident coronary heart disease events in an adult population: Multi-Ethnic Study of Atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 1.14
Circadian variation and responsiveness of hydration biomarkers to changes in daily water intake. Eur J Appl Physiol (2013) 1.14
High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease. Arterioscler Thromb Vasc Biol (2003) 1.13
ABCA1-mediated cholesterol efflux generates microparticles in addition to HDL through processes governed by membrane rigidity. J Lipid Res (2008) 1.12
Plant tissues in 3D via X-ray tomography: simple contrasting methods allow high resolution imaging. PLoS One (2013) 1.10
Liver-specific deficiency of serine palmitoyltransferase subunit 2 decreases plasma sphingomyelin and increases apolipoprotein E levels. J Biol Chem (2009) 1.08
Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients. Cytometry A (2006) 1.06
Phospholipid transfer protein deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E. J Biol Chem (2002) 1.06
Phospholipid transfer protein (PLTP) deficiency reduces brain vitamin E content and increases anxiety in mice. FASEB J (2004) 1.03
The domain responsible for sphingomyelin synthase (SMS) activity. Biochim Biophys Acta (2008) 1.02
Sphingomyelin and its role in cellular signaling. Adv Exp Med Biol (2013) 1.02
Mapping of liver fat with triple-echo gradient echo imaging: validation against 3.0-T proton MR spectroscopy. Eur Radiol (2009) 1.02
Anti-inflammatory effects of phospholipid transfer protein (PLTP) deficiency in mice. Biochim Biophys Acta (2005) 1.02
7-ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for alpha-tocopherol with consequences on cell death. J Biol Chem (2009) 1.01
Myocardial injury in critically ill patients: relation to increased cardiac troponin I and hospital mortality. Chest (2005) 1.00
Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL. J Lipid Res (2008) 1.00
Why do results conflict regarding the prognostic value of the methylation status in colon cancers? The role of the preservation method. BMC Cancer (2012) 0.99
PLTP deficiency improves the anti-inflammatory properties of HDL and reduces the ability of LDL to induce monocyte chemotactic activity. J Lipid Res (2004) 0.99
Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice. Arterioscler Thromb Vasc Biol (2012) 0.99
Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells. J Lipid Res (2003) 0.99
Identification and verification of heat shock protein 60 as a potential serum marker for colorectal cancer. FEBS J (2011) 0.98
Small stress proteins: novel negative modulators of apoptosis induced independently of reactive oxygen species. Prog Mol Subcell Biol (2002) 0.98
Induction of transglutaminase 2 by a liver X receptor/retinoic acid receptor alpha pathway increases the clearance of apoptotic cells by human macrophages. Circ Res (2009) 0.98
The effect of dietary sphingolipids on plasma sphingomyelin metabolism and atherosclerosis. Biochim Biophys Acta (2005) 0.98
Phospholipid transfer protein-deficient mice absorb less cholesterol. Arterioscler Thromb Vasc Biol (2007) 0.97
Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression. Arterioscler Thromb Vasc Biol (2006) 0.96
Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release. Biochimie (2003) 0.95
Specifically PNPLA3-mediated accumulation of liver fat in obese patients with type 2 diabetes. J Clin Endocrinol Metab (2010) 0.95
FRET multiphoton spectral imaging microscopy of 7-ketocholesterol and Nile Red in U937 monocytic cells loaded with 7-ketocholesterol. Anal Quant Cytol Histol (2004) 0.94