Published in Acta Med Okayama on April 01, 2008
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The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif. J Biol Chem (2003) 3.83
Analysis of fecal DNA methylation to detect gastrointestinal neoplasia. J Natl Cancer Inst (2009) 2.57
In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation. Proc Natl Acad Sci U S A (2009) 2.46
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Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes. Nat Biotechnol (2006) 2.21
A human beta-cell line for transplantation therapy to control type 1 diabetes. Nat Biotechnol (2005) 2.12
A new cell-permeable peptide allows successful allogeneic islet transplantation in mice. Nat Med (2004) 2.01
Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection. Cell Cycle (2011) 1.76
Impact of olmesartan on progression of coronary atherosclerosis a serial volumetric intravascular ultrasound analysis from the OLIVUS (impact of OLmesarten on progression of coronary atherosclerosis: evaluation by intravascular ultrasound) trial. J Am Coll Cardiol (2010) 1.76
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Time-dependent changes in plasma osteopontin levels in patients with anterior-wall acute myocardial infarction after successful reperfusion: correlation with left-ventricular volume and function. J Lab Clin Med (2005) 1.67
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Intramuscular transplantation of engineered hepatic tissue constructs corrects acute and chronic liver failure in mice. J Hepatol (2009) 1.64
Antitumor activity of IFN-lambda in murine tumor models. J Immunol (2006) 1.63
Current venous thromboembolism management and outcomes in Japan. Circ J (2014) 1.62
Selective metastatic tumor labeling with green fluorescent protein and killing by systemic administration of telomerase-dependent adenoviruses. Mol Cancer Ther (2009) 1.61
An assessment of the feasibility of sentinel lymph node-guided surgery for gastric cancer. Gastric Cancer (2004) 1.61
CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin. Cancer Res (2003) 1.57
"Firefly rats" as an organ/cellular source for long-term in vivo bioluminescent imaging. Transplantation (2006) 1.54
Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model. J Mol Cell Cardiol (2006) 1.52
Evidence-based risk factors for seroma formation in breast surgery. Jpn J Clin Oncol (2006) 1.51
Human monocyte-derived dendritic cells pulsed with wild-type p53 protein efficiently induce CTLs against p53 overexpressing human cancer cells. Clin Cancer Res (2005) 1.50
Mechanism of impaired regeneration of fatty liver in mouse partial hepatectomy model. J Gastroenterol Hepatol (2007) 1.46
Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect. Stem Cells (2009) 1.45
Minimally invasive aortic valve replacement surgery: comparison of port-access and conventional standard approach. Circ J (2011) 1.44
Pathophysiology of seroma in breast cancer. Breast Cancer (2005) 1.43
Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer. Gastroenterology (2008) 1.43
Preoperative chronic kidney disease as a strong predictor of postoperative infection and mortality after coronary artery bypass grafting. Circ J (2014) 1.43
Successful fluorescence-guided surgery on human colon cancer patient-derived orthotopic xenograft mouse models using a fluorophore-conjugated anti-CEA antibody and a portable imaging system. J Laparoendosc Adv Surg Tech A (2014) 1.40
Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury. Stem Cells (2006) 1.38
Reliability and validity of the Parenting Scale of Inconsistency. Psychol Rep (2006) 1.38
Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein. Eur J Neurosci (2006) 1.36
A simple biological imaging system for detecting viable human circulating tumor cells. J Clin Invest (2009) 1.36
The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis. Gastroenterology (2008) 1.34
Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate. Neoplasia (2011) 1.34
The outcome of living donor liver transplantation with prior spontaneous large portasystemic shunts. Transpl Int (2007) 1.32
Telomerase-specific replication-selective virotherapy for human cancer. Clin Cancer Res (2004) 1.32
Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells. Int J Mol Med (2004) 1.30
Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: preclinical evaluation of chemovirotherapy. Int J Cancer (2006) 1.27
Interaction of synaptic scaffolding molecule and Beta -catenin. J Neurosci (2002) 1.26
Leiomyomatosis peritonealis disseminata coexisting with endometriosis within the same lesions: a case report with review of the literature. Int J Clin Exp Pathol (2013) 1.26
Role of inherited defects of MYH in the development of sporadic colorectal cancer. Genes Chromosomes Cancer (2004) 1.26
Heparanase expression correlates with invasion and poor prognosis in gastric cancers. Lab Invest (2003) 1.25
Development of new inbred transgenic strains of rats with LacZ or GFP. Biochem Biophys Res Commun (2005) 1.24
Visualization of intrathoracically disseminated solid tumors in mice with optical imaging by telomerase-specific amplification of a transferred green fluorescent protein gene. Cancer Res (2004) 1.22
Differentiation of mouse embryonic stem cells to hepatocyte-like cells by co-culture with human liver nonparenchymal cell lines. Nat Protoc (2007) 1.22
A granulomatous liver abscess which developed after a toothpick penetrated the gastrointestinal tract: report of a case. Surg Today (2003) 1.22
Hypermethylation of O6-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer cases. Clin Cancer Res (2003) 1.22
Analysis of reactive oxygen metabolites (ROMs) after cardiovascular surgery as a marker of oxidative stress. Acta Med Okayama (2010) 1.20
Long-term prognosis of patients with type a aortic intramural hematoma. Circulation (2002) 1.19
Effect of mechanical closure of dead space on seroma formation after breast surgery. Breast Cancer (2006) 1.18
Surgical treatments for multiple primary adenocarcinoma of the lung. Ann Thorac Surg (2004) 1.18
E-prostanoid (EP)2/EP4 receptor-dependent maturation of human monocyte-derived dendritic cells and induction of helper T2 polarization. J Pharmacol Exp Ther (2004) 1.17
Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis. Int J Cancer (2008) 1.15
Objective radiologic analysis of ground-glass opacity aimed at curative limited resection for small peripheral non-small cell lung cancer. J Thorac Cardiovasc Surg (2005) 1.12
Glutamine is a key regulator for amino acid-controlled cell growth through the mTOR signaling pathway in rat intestinal epithelial cells. Biochem Biophys Res Commun (2005) 1.12
Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT. Transplantation (2004) 1.12
Effects of prophylactic splenic artery modulation on portal overperfusion and liver regeneration in small-for-size graft. Transplantation (2008) 1.12
ICAM-1 expression and the soluble ICAM-1 level for evaluating the metastatic potential of gastric cancer. Int J Cancer (2002) 1.11
Nationwide survey for bisphosphonate-related osteonecrosis of the jaws in Japan. J Oral Maxillofac Surg (2011) 1.11
Hallucinatory experiences in a community sample of Japanese children. J Am Acad Child Adolesc Psychiatry (2004) 1.11
Stimulation of alpha7 nicotinic acetylcholine receptor inhibits CD14 and the toll-like receptor 4 expression in human monocytes. Shock (2006) 1.09
A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats. J Surg Res (2006) 1.08
Resistance to paclitaxel therapy is related with Bcl-2 expression through an estrogen receptor mediated pathway in breast cancer. Int J Oncol (2009) 1.08
Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD'). Oncogene (2005) 1.08
Two cases of acute bioprosthetic mitral valve thrombosis immediately after mitral valve replacement. Circulation (2014) 1.06
Preoperative proximal splenic artery embolization: a safe and efficacious portal decompression technique that improves the outcome of live donor liver transplantation. Transpl Int (2007) 1.06
Prostaglandin E(2) inhibits IL-18-induced ICAM-1 and B7.2 expression through EP2/EP4 receptors in human peripheral blood mononuclear cells. J Immunol (2002) 1.05
Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination. J Hepatol (2007) 1.04
KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts. Circulation (2005) 1.04
Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer. Int J Oncol (2006) 1.04
Soluble P-selectin and thrombomodulin-protein C-Protein S pathway in cyanotic congenital heart disease with secondary erythrocytosis. Thromb Res (2003) 1.04
Treatment for prolapse of the sigmoid neovagina in Mayer-Rokitansky-Kuster-Hauser syndrome. Obstet Gynecol (2002) 1.03
Heparanase regulates esophageal keratinocyte differentiation through nuclear translocation and heparan sulfate cleavage. Differentiation (2006) 1.02
Metabolomic analysis of human plasma from haemodialysis patients. Eur J Clin Invest (2010) 1.02
Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines. Oncol Rep (2007) 1.01
Thoracic tumors treated with CT-guided radiofrequency ablation: initial experience. Radiology (2004) 1.01
Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers. Transplantation (2003) 1.01
Usefulness of dabigatran etexilate as periprocedural anticoagulation therapy for atrial fibrillation ablation. Clin Drug Investig (2013) 1.00
Localization of heparanase in esophageal cancer cells: respective roles in prognosis and differentiation. Lab Invest (2004) 1.00
Intrapericardial diaphragmatic hernia after coronary artery bypass grafting using the right gastroepiploic artery graft: report of a case. Ann Thorac Cardiovasc Surg (2011) 1.00
Primary malignant melanoma of the esophagus: long-term survival following pre- and postoperative adjuvant hormone/chemotherapy. Dig Dis Sci (2004) 1.00
Serum gamma-interferon-inducing factor (IL-18) and IL-10 levels in patients with acute hepatitis and fulminant hepatic failure. J Gastroenterol Hepatol (2002) 1.00
Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT. Transplantation (2004) 1.00
Clinical effect of CO(2) laser in reducing pain in orthodontics. Angle Orthod (2008) 1.00
Gene delivery to embryonic stem cells. Birth Defects Res C Embryo Today (2005) 1.00
Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages. J Biol Chem (2003) 0.99
Ascending aortic aneurysm in a patient with an aortic Starr-Edwards ball valve prosthesis implanted 39 years previously. Gen Thorac Cardiovasc Surg (2010) 0.98
Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector. Biochem Biophys Res Commun (2005) 0.98
Establishment of an immortalized human hepatic stellate cell line to develop antifibrotic therapies. Cell Transplant (2003) 0.98
Transplantation of engineered chimeric liver with autologous hepatocytes and xenobiotic scaffold. Ann Surg (2013) 0.98
Heparanase is involved in angiogenesis in esophageal cancer through induction of cyclooxygenase-2. Clin Cancer Res (2005) 0.97