Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration.

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Published in Mol Pharmacol on February 01, 1991

Authors

P T Campbell1, M Hnatowich, B F O'Dowd, M G Caron, R J Lefkowitz, W P Hausdorff

Author Affiliations

1: Howard Hughes Medical Institute, Department of Medicine (Cardiology), Duke University Medical Center, Durham, North Carolina 27710.

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