Published in BMC Med Genomics on May 14, 2008
Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics. Proc Natl Acad Sci U S A (2014) 1.52
Multiple pathways in the FGF signaling network are frequently deregulated by gene amplification in oral dysplasias. Int J Cancer (2009) 1.02
Bayesian clustering and feature selection for cancer tissue samples. BMC Bioinformatics (2009) 0.93
A hidden Markov model-based algorithm for identifying tumour subtype using array CGH data. BMC Genomics (2011) 0.85
An algorithm for classifying tumors based on genomic aberrations and selecting representative tumor models. BMC Med Genomics (2010) 0.83
SNP and gene networks construction and analysis from classification of copy number variations data. BMC Bioinformatics (2011) 0.81
Loss of fragile histidine triad and amplification of 1p36.22 and 11p15.5 in primary gastric adenocarcinomas. World J Gastroenterol (2012) 0.77
Amplification and overexpression of CTTN and CCND1 at chromosome 11q13 in Esophagus squamous cell carcinoma (ESCC) of North Eastern Chinese Population. Int J Med Sci (2016) 0.75
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Chromatin architecture of the human genome: gene-rich domains are enriched in open chromatin fibers. Cell (2004) 5.84
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A role for common fragile site induction in amplification of human oncogenes. Cancer Cell (2002) 2.63
Neuroblastoma: biology and molecular and chromosomal pathology. Lancet Oncol (2003) 2.22
Specificity, selection and significance of gene amplifications in cancer. Semin Cancer Biol (2006) 1.86
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The molecular basis of common and rare fragile sites. Cancer Lett (2005) 1.68
Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas. Proc Natl Acad Sci U S A (2004) 1.56
Manifestation, mechanisms and mysteries of gene amplifications. Cancer Lett (2005) 1.53
DNA copy number amplification profiling of human neoplasms. Oncogene (2006) 1.25
Chromosome rearrangements resulting from telomere dysfunction and their role in cancer. Bioessays (2004) 1.24
Practical identifiability of finite mixtures of multivariate bernoulli distributions. Neural Comput (2000) 0.84
Clinical factors associated with Merkel cell polyomavirus infection in Merkel cell carcinoma. J Natl Cancer Inst (2009) 3.17
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas. Science (2011) 3.17
Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups. J Clin Oncol (2005) 2.17
CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma -A miRNA microarray analysis. Genes Chromosomes Cancer (2009) 2.09
Uniparental disomy in cancer. Trends Mol Med (2009) 1.99
Specificity, selection and significance of gene amplifications in cancer. Semin Cancer Biol (2006) 1.86
Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS. Genes Chromosomes Cancer (2013) 1.77
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. Carcinogenesis (2006) 1.70
Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer. Cancer Genet Cytogenet (2004) 1.54
Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families. Cancer Res (2002) 1.54
Manifestation, mechanisms and mysteries of gene amplifications. Cancer Lett (2005) 1.53
Formation of trisomies and their parental origin in hyperdiploid childhood acute lymphoblastic leukemia. Blood (2003) 1.52
Targets of gene amplification and overexpression at 17q in gastric cancer. Cancer Res (2002) 1.46
Driver gene mutations of non-small-cell lung cancer are rare in primary carcinoids of the lung: NGS study by ion Torrent. Lung (2015) 1.45
Merkel cell polyomavirus infection, large T antigen, retinoblastoma protein and outcome in Merkel cell carcinoma. Clin Cancer Res (2011) 1.44
Undifferentiated intimal sarcoma of large systemic blood vessels: report of 14 cases with immunohistochemical profile and review of the literature. Am J Surg Pathol (2005) 1.40
CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer. Genes Chromosomes Cancer (2005) 1.38
Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array. Oncogene (2002) 1.38
Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis. Haematologica (2002) 1.37
Clinical course of nonvisceral soft tissue leiomyosarcoma in 225 patients from the Scandinavian Sarcoma Group. Cancer (2007) 1.36
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. J Pathol (2012) 1.34
Gastric cancers overexpress DARPP-32 and a novel isoform, t-DARPP. Cancer Res (2002) 1.33
Acute lymphoblastic leukemia in adolescents and young adults in Finland. Haematologica (2008) 1.32
Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study. Clin Cancer Res (2003) 1.31
Tumor infiltrating immune cells and outcome of Merkel cell carcinoma: a population-based study. Clin Cancer Res (2012) 1.29
MicroRNA profiling differentiates colorectal cancer according to KRAS status. Genes Chromosomes Cancer (2011) 1.24
Distinct differentiation characteristics of individual human embryonic stem cell lines. BMC Dev Biol (2006) 1.24
Genome-wide differences between microsatellite stable and unstable colorectal tumors. Carcinogenesis (2005) 1.23
Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations. Oncogene (2005) 1.22
Darpp-32: a novel antiapoptotic gene in upper gastrointestinal carcinomas. Cancer Res (2005) 1.19
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion. Clin Cancer Res (2009) 1.19
Can bladder adenocarcinomas be distinguished from schistosomiasis-associated bladder cancers by using array comparative genomic hybridization analysis? Cancer Genet Cytogenet (2007) 1.16
Targeted resequencing reveals ALK fusions in non-small cell lung carcinomas detected by FISH, immunohistochemistry, and real-time RT-PCR: a comparison of four methods. Biomed Res Int (2013) 1.15
Epigenetic signatures of familial cancer are characteristic of tumor type and family category. Cancer Res (2008) 1.15
Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines. BMC Genomics (2007) 1.12
Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators. Oncogene (2004) 1.12
Cytogenetic and molecular genetic changes in malignant mesothelioma. Cancer Genet Cytogenet (2006) 1.12
Array CGH in molecular diagnosis of mental retardation - A study of 150 Finnish patients. Am J Med Genet A (2010) 1.12
Genomic profiling of chondrosarcoma: chromosomal patterns in central and peripheral tumors. Clin Cancer Res (2009) 1.12
ALK/EML4 fusion gene may be found in pure squamous carcinoma of the lung. J Thorac Oncol (2014) 1.11
Integrated gene copy number and expression microarray analysis of gastric cancer highlights potential target genes. Int J Cancer (2008) 1.07
Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome. J Clin Oncol (2009) 1.07
Aberrant expression of HOXA9, DEK, CBL and CSF1R in acute myeloid leukemia. Leuk Lymphoma (2003) 1.07
Genomic imbalances in Schistosoma-associated and non-Schistosoma-associated bladder carcinoma. An array comparative genomic hybridization analysis. Cancer Genet Cytogenet (2007) 1.06
Abnormal expression of apoptosis-related genes in haematological malignancies: overexpression of MYC is poor prognostic sign in mantle cell lymphoma. Br J Haematol (2003) 1.05
Combined use of expression and CGH arrays pinpoints novel candidate genes in Ewing sarcoma family of tumors. BMC Cancer (2009) 1.04
Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes. Genes Chromosomes Cancer (2007) 1.04
Changes in apoptosis-related pathways in acute myelocytic leukemia. Cancer Genet Cytogenet (2003) 1.01
Second cancers following the diagnosis of Merkel cell carcinoma: a nationwide cohort study. Cancer Epidemiol (2010) 1.00
Targeted resequencing of 9p in acute lymphoblastic leukemia yields concordant results with array CGH and reveals novel genomic alterations. Genomics (2013) 1.00
Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma. Cancer Genet Cytogenet (2002) 1.00
Gene expression analysis of 1,25(OH)2D3-dependent differentiation of HL-60 cells: a cDNA array study. Br J Haematol (2002) 1.00
Gene amplifications in osteosarcoma-CGH microarray analysis. Genes Chromosomes Cancer (2005) 0.99
CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: an array CGH study. Leuk Res (2008) 0.99
Predictive value of histopathologic parameters in early squamous cell carcinoma of oral tongue. Oral Oncol (2007) 0.99
Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer. Genes Chromosomes Cancer (2011) 0.99
Spindle cell tumours of the pleura: a clinical, histological and comparative genomic hybridization analysis of 14 cases. Virchows Arch (2005) 0.99
Coamplified and overexpressed genes at ERBB2 locus in gastric cancer. Int J Cancer (2004) 0.98
Array comparative genomic hybridization analysis of chromosomal imbalances and their target genes in gastrointestinal stromal tumors. Genes Chromosomes Cancer (2007) 0.98
Ultrastructural and chromosomal studies on manganese superoxide dismutase in malignant mesothelioma. Am J Respir Cell Mol Biol (2004) 0.98
Does comparative genomic hybridization reveal distinct differences in DNA copy number sequence patterns between leiomyosarcoma and malignant fibrous histiocytoma? Cancer Genet Cytogenet (2008) 0.98
Identification of specific gene copy number changes in asbestos-related lung cancer. Cancer Res (2006) 0.97
Incidence of Merkel cell carcinoma in renal transplant recipients. Nephrol Dial Transplant (2009) 0.97
Molecular dissection of 17q12 amplicon in upper gastrointestinal adenocarcinomas. Mol Cancer Res (2006) 0.97
CanGEM: mining gene copy number changes in cancer. Nucleic Acids Res (2007) 0.97
Genomic profiles and CRTC1-MAML2 fusion distinguish different subtypes of mucoepidermoid carcinoma. Mod Pathol (2012) 0.96
Microscopic margins and results of surgery for dermatofibrosarcoma protuberans. Plast Reconstr Surg (2007) 0.96
Investigatory and analytical approaches to differential gene expression profiling in mantle cell lymphoma. Br J Haematol (2002) 0.96
DNA copy number aberrations in intestinal-type gastric cancer revealed by array-based comparative genomic hybridization. Cancer Genet Cytogenet (2006) 0.96
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21. Oncogene (2002) 0.95
MicroRNA profiling predicts survival in anti-EGFR treated chemorefractory metastatic colorectal cancer patients with wild-type KRAS and BRAF. Cancer Genet (2012) 0.94
Incidence, epidemiology and treatment results of osteosarcoma in Finland - a nationwide population-based study. Acta Oncol (2011) 0.94
Association of Merkel cell polyomavirus infection with tumor p53, KIT, stem cell factor, PDGFR-alpha and survival in Merkel cell carcinoma. Int J Cancer (2011) 0.94
Down-regulation of miR-181c in imatinib-resistant chronic myeloid leukemia. Mol Cytogenet (2013) 0.93
Recurrent DNA sequence copy losses on chromosomal arm 6q in capillary hemangioblastoma. Cancer Genet Cytogenet (2002) 0.92
Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample. Eur J Hum Genet (2007) 0.92
Caveolins as tumour markers in lung cancer detected by combined use of cDNA and tissue microarrays. J Pathol (2004) 0.92
Gene copy number profiling of soft-tissue leiomyosarcomas by array-comparative genomic hybridization. Cancer Genet Cytogenet (2006) 0.91
RELP, a novel human REG-like protein with up-regulated expression in inflammatory and metaplastic gastrointestinal mucosa. Am J Pathol (2003) 0.91
Clustering of molecular alterations in gastroesophageal carcinomas. Neoplasia (2004) 0.91
Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system. Mol Cell Neurosci (2005) 0.90
Amplified, lost, and fused genes in 11q23-25 amplicon in acute myeloid leukemia, an array-CGH study. Genes Chromosomes Cancer (2006) 0.90
Single nucleotide polymorphism microarray analysis of karyotypically normal acute myeloid leukemia reveals frequent copy number neutral loss of heterozygosity. Haematologica (2008) 0.90
BRAF V600E mutation does not predict recurrence after long-term follow-up in TNM stage I or II papillary thyroid carcinoma patients. APMIS (2011) 0.90