Published in Respir Res on May 18, 2008
Extracellular matrix molecules: potential targets in pharmacotherapy. Pharmacol Rev (2009) 1.90
Emphysema and mechanical stress-induced lung remodeling. Physiology (Bethesda) (2013) 1.32
Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease. PLoS One (2011) 1.16
Tissue elasticity and the ageing elastic fibre. Age (Dordr) (2009) 1.14
Altered fibroblast proteoglycan production in COPD. Respir Res (2010) 1.14
Polyinosine-polycytidylic acid stimulates versican accumulation in the extracellular matrix promoting monocyte adhesion. Am J Respir Cell Mol Biol (2009) 1.10
Proteoglycans: key regulators of pulmonary inflammation and the innate immune response to lung infection. Anat Rec (Hoboken) (2010) 1.06
Elastin expression in very severe human COPD. Eur Respir J (2009) 1.06
Similar matrix alterations in alveolar and small airway walls of COPD patients. BMC Pulm Med (2014) 0.92
Controlled and uncontrolled asthma display distinct alveolar tissue matrix compositions. Respir Res (2014) 0.90
Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition. PLoS One (2014) 0.89
DAMPs activating innate and adaptive immune responses in COPD. Mucosal Immunol (2013) 0.89
A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease. Matrix Biol (2014) 0.88
A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α. Am J Physiol Lung Cell Mol Physiol (2014) 0.87
Proteoglycans maintain lung stability in an elastase-treated mouse model of emphysema. Am J Respir Cell Mol Biol (2014) 0.87
Versican in inflammation and tissue remodeling: the impact on lung disorders. Glycobiology (2014) 0.85
Reprint of: A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease. Matrix Biol (2014) 0.83
Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung. J Cell Mol Med (2012) 0.83
Inhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trial. PLoS One (2013) 0.82
Matrix Remodeling in Pulmonary Fibrosis and Emphysema. Am J Respir Cell Mol Biol (2016) 0.80
Airway and Extracellular Matrix Mechanics in COPD. Front Physiol (2015) 0.80
RNA interference targeting carbohydrate sulfotransferase 3 diminishes macrophage accumulation, inhibits MMP-9 expression and promotes lung recovery in murine pulmonary emphysema. Respir Res (2015) 0.79
Sonic Hedgehog Signaling Regulates Myofibroblast Function During Alveolar Septum Formation in Murine Postnatal Lung. Am J Respir Cell Mol Biol (2017) 0.78
Accelerated extracellular matrix turnover during exacerbations of COPD. Respir Res (2015) 0.78
Genome-wide association and network analysis of lung function in the Framingham Heart Study. Genet Epidemiol (2014) 0.78
The extracellular matrix - the under-recognized element in lung disease? J Pathol (2016) 0.78
Inhibition of versican expression by siRNA facilitates tropoelastin synthesis and elastic fiber formation by human SK-LMS-1 leiomyosarcoma smooth muscle cells in vitro and in vivo. Matrix Biol (2015) 0.77
Correlation of Versican Expression, Accumulation, and Degradation during Embryonic Development by Quantitative Immunohistochemistry. J Histochem Cytochem (2015) 0.76
Versican V1 Overexpression Induces a Myofibroblast-Like Phenotype in Cultured Fibroblasts. PLoS One (2015) 0.76
Deposition of insoluble elastin by pulmonary fibroblasts from patients with COPD is increased by treatment with versican siRNA. Int J Chron Obstruct Pulmon Dis (2017) 0.75
Versican deficiency significantly reduces lung inflammatory response induced by polyinosine-polycytidylic acid stimulation. J Biol Chem (2016) 0.75
Interplay of extracellular matrix and leukocytes in lung inflammation. Cell Immunol (2016) 0.75
Versican accumulates in vascular lesions in pulmonary arterial hypertension. Pulm Circ (2016) 0.75
Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest (2000) 2.92
Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am J Respir Crit Care Med (1997) 2.55
Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema. Lab Invest (1998) 1.97
Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects. Respir Med (2003) 1.97
Changes in elastic fibres in the small airways and alveoli in COPD. Eur Respir J (2008) 1.87
Collagen and elastin in human pulmonary emphysema. Am Rev Respir Dis (1993) 1.86
Animal models of emphysema. Am Rev Respir Dis (1986) 1.67
Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly. Am J Pathol (2000) 1.66
The elastin receptor: a galactoside-binding protein. Science (1988) 1.57
Emphysema: the first two centuries--and beyond. A historical overview, with suggestions for future research: Part 2. Am Rev Respir Dis (1992) 1.55
Ligand affinity of the 67-kD elastin/laminin binding protein is modulated by the protein's lectin domain: visualization of elastin/laminin-receptor complexes with gold-tagged ligands. J Cell Biol (1991) 1.48
Enhanced proteoglycan deposition in the airway wall of atopic asthmatics. Am J Respir Crit Care Med (1999) 1.43
The 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding protein. J Biol Chem (1998) 1.36
MMP-2- and MMP-9-linked gelatinolytic activity in the sputum from patients with asthma and chronic obstructive pulmonary disease. Int Arch Allergy Immunol (2000) 1.33
The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase. J Clin Invest (1993) 1.29
Impaired elastin fiber assembly related to reduced 67-kD elastin-binding protein in fetal lamb ductus arteriosus and in cultured aortic smooth muscle cells treated with chondroitin sulfate. J Clin Invest (1991) 1.28
Elastin content of normal and emphysematous lung parenchyma. Am J Med (1980) 1.26
Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury. Circ Res (2005) 1.24
Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients. Am J Pathol (2004) 1.21
Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly. J Biol Chem (2005) 1.20
67-kD elastin-binding protein is a protective "companion" of extracellular insoluble elastin and intracellular tropoelastin. J Cell Biol (1994) 1.18
Decreased elastin deposition and high proliferation of fibroblasts from Costello syndrome are related to functional deficiency in the 67-kD elastin-binding protein. Am J Hum Genet (2000) 1.16
Proteoglycan deposition in pulmonary fibrosis. Am J Respir Crit Care Med (1996) 1.16
Elastic tissue of normal and emphysematous lungs. A tridimensional histologic study. Am J Pathol (1961) 1.12
Morphogenesis of abnormal elastic fibers in lungs of patients with panacinar and centriacinar emphysema. Hum Pathol (1989) 1.11
Remodeling of alveolar walls after elastase treatment of hamsters. Results of elastin and collagen mRNA in situ hybridization. Am J Respir Crit Care Med (1998) 1.09
Versican/PG-M isoforms in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (1999) 1.08
Biological roles of the non-integrin elastin/laminin receptor. Biol Chem (1997) 1.07
Lung lining fluid glutathione attenuates IL-13-induced asthma. Am J Respir Cell Mol Biol (2007) 1.06
Nature and the multiple functions of the 67-kD elastin-/laminin binding protein. Cell Adhes Commun (1994) 1.06
Ultrastructural changes in hamster lung four hours to twenty-four days after exposure to elastase. Anat Rec (1981) 1.03
Proteoglycan changes in the extracellular matrix of lung tissue from patients with pulmonary emphysema. Mod Pathol (1999) 1.03
An introduction to matrikines: extracellular matrix-derived peptides which regulate cell activity. Implication in tumor invasion. Crit Rev Oncol Hematol (2004) 1.00
Changes in collagen fibril diameters across artery walls including a correlation with glycosaminoglycan content. Connect Tissue Res (1987) 0.99
Vascular smooth muscle cell detachment from elastin and migration through elastic laminae is promoted by chondroitin sulfate-induced "shedding" of the 67-kDa cell surface elastin binding protein. Exp Cell Res (1992) 0.98
Matrix proteoglycans and remodelling of interstitial lung tissue in lymphangioleiomyomatosis. J Pathol (2004) 0.95
Proteoglycans in granulomatous lung diseases. Eur Respir J (1997) 0.92
Glycosaminoglycans in emphysematous and fibrotic hamster lungs. Am Rev Respir Dis (1982) 0.90
Ultrastructural alterations in collagen associated with microscopic foci of human emphysema. Hum Pathol (1977) 0.88
Cigarette smoke impairs elastin resynthesis in lungs of hamsters with elastase-induced emphysema. Am Rev Respir Dis (1985) 0.88
Changes in versican and chondroitin sulfate proteoglycans during structural development of the lung. Am J Physiol Regul Integr Comp Physiol (2007) 0.87
The development of alveolar septa in fetal sheep lung. An ultrastructural and immunohistochemical study. Am J Anat (1983) 0.84
Comparison of deposits of versican, biglycan and decorin in saphenous vein and internal thoracic, radial and coronary arteries: correlation to patency. Coron Artery Dis (2001) 0.83
Biosynthesis of hyaluronic acid, heparan sulfate and structural glycoproteins in hamster lung explants during elastase induced emphysema. Connect Tissue Res (1985) 0.82
Biochemical study of ground substance in normal and emphysematous lungs. Am Rev Respir Dis (1967) 0.80
The effect of telithromycin in acute exacerbations of asthma. N Engl J Med (2006) 5.35
Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature (2002) 3.60
Human tissue-engineered blood vessels for adult arterial revascularization. Nat Med (2006) 3.39
Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease. Cochrane Database Syst Rev (2011) 3.27
Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration. Arterioscler Thromb Vasc Biol (2007) 2.58
Hyaluronan-cell interactions in cancer and vascular disease. J Biol Chem (2001) 2.45
Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2006) 2.28
Serum factors from pseudoxanthoma elasticum patients alter elastic fiber formation in vitro. J Invest Dermatol (2006) 2.27
Short sleep duration in middle childhood: risk factors and consequences. Sleep (2008) 2.19
Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1. J Biol Chem (2003) 2.10
SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength. J Invest Dermatol (2003) 1.98
Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging. Arterioscler Thromb Vasc Biol (2010) 1.96
Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion. Diabetes (2007) 1.95
Enhanced extracellular matrix accumulation in restenosis of coronary arteries after stent deployment. J Am Coll Cardiol (2002) 1.92
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. Proc Natl Acad Sci U S A (2012) 1.91
Extracellular matrix molecules: potential targets in pharmacotherapy. Pharmacol Rev (2009) 1.90
Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis. Development (2005) 1.88
Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways. Arterioscler Thromb Vasc Biol (2005) 1.87
The ADAMTS proteases, extracellular matrix, and vascular disease: waking the sleeping giant(s)! Arterioscler Thromb Vasc Biol (2005) 1.76
Hyaluronan-dependent pericellular matrix. Adv Drug Deliv Rev (2007) 1.73
Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice. Circulation (2006) 1.69
Intracellular hyaluronan: a new frontier for inflammation? Biochim Biophys Acta (2004) 1.64
Increase in serum amyloid a evoked by dietary cholesterol is associated with increased atherosclerosis in mice. Circulation (2004) 1.61
Elastic fibres and vascular structure in hypertension. Pharmacol Ther (2006) 1.58
Connection between elastin haploinsufficiency and increased cell proliferation in patients with supravalvular aortic stenosis and Williams-Beuren syndrome. Am J Hum Genet (2002) 1.54
Heightened aberrant deposition of hard-wearing elastin in conduit arteries of prehypertensive SHR is associated with increased stiffness and inward remodeling. Am J Physiol Heart Circ Physiol (2008) 1.52
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease. Cochrane Database Syst Rev (2010) 1.47
Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycans. Cardiovasc Res (2008) 1.44
Serum amyloid A and lipoprotein retention in murine models of atherosclerosis. Arterioscler Thromb Vasc Biol (2005) 1.43
Cutting edge: high molecular weight hyaluronan promotes the suppressive effects of CD4+CD25+ regulatory T cells. J Immunol (2007) 1.38
Triglyceride-rich lipoproteins from subjects with type 2 diabetes do not demonstrate increased binding to biglycan, a vascular proteoglycan. J Clin Endocrinol Metab (2002) 1.38
Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension. Circ Res (2005) 1.37
The regulated synthesis of versican, decorin, and biglycan: extracellular matrix proteoglycans that influence cellular phenotype. Crit Rev Eukaryot Gene Expr (2004) 1.36
A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol (2008) 1.35
A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair Regen (2006) 1.33
Extracellular matrix changes in stented human coronary arteries. Circulation (2004) 1.32
Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion. Arterioscler Thromb Vasc Biol (2002) 1.31
Glycosaminoglycans and proteoglycans in normal mitral valve leaflets and chordae: association with regions of tensile and compressive loading. Glycobiology (2004) 1.30
CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta. J Immunol (2009) 1.28
Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro. J Cell Physiol (2002) 1.27
Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury. Circ Res (2005) 1.24
Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs. J Immunol (2010) 1.23
Versican degradation and vascular disease. Trends Cardiovasc Med (2006) 1.23
Signaling pathways transduced through the elastin receptor facilitate proliferation of arterial smooth muscle cells. J Biol Chem (2002) 1.21
Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients. Am J Pathol (2004) 1.21
Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways. Circulation (2008) 1.20
Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells. J Leukoc Biol (2009) 1.20
Risk factors for obesity in 7-year-old European children: the Auckland Birthweight Collaborative Study. Arch Dis Child (2007) 1.19
Pro- and anti-inflammatory factors cooperate to control hyaluronan synthesis in lung fibroblasts. Am J Respir Cell Mol Biol (2004) 1.18
ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors. Proc Natl Acad Sci U S A (2011) 1.17
Alterations in the lens capsule contribute to cataractogenesis in SPARC-null mice. J Cell Sci (2002) 1.17
Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue. Am J Respir Cell Mol Biol (2003) 1.17
VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases. EMBO J (2008) 1.15
Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation. Circ Res (2008) 1.15
Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration. Matrix Biol (2011) 1.15
A novel rat model of carotid artery stenting for the understanding of restenosis in metabolic diseases. J Vasc Res (2002) 1.14
Organization of hyaluronan and versican in the extracellular matrix of human fibroblasts treated with the viral mimetic poly I:C. J Histochem Cytochem (2009) 1.13
Overexpression of hyaluronan synthases alters vascular smooth muscle cell phenotype and promotes monocyte adhesion. J Cell Physiol (2006) 1.13
Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD. Respir Med (2010) 1.12
Proteoglycans synthesized by arterial smooth muscle cells in the presence of transforming growth factor-beta1 exhibit increased binding to LDLs. Arterioscler Thromb Vasc Biol (2002) 1.11
Polyinosine-polycytidylic acid stimulates versican accumulation in the extracellular matrix promoting monocyte adhesion. Am J Respir Cell Mol Biol (2009) 1.10
Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1. Circulation (2008) 1.10
Matricellular hevin regulates decorin production and collagen assembly. J Biol Chem (2006) 1.09
Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans. Arterioscler Thromb Vasc Biol (2011) 1.08
Intracellular hyaluronan in arterial smooth muscle cells: association with microtubules, RHAMM, and the mitotic spindle. J Histochem Cytochem (2004) 1.07
Developing vasculature and stroma in engineered human myocardium. Tissue Eng Part A (2011) 1.07
Proteoglycans: key regulators of pulmonary inflammation and the innate immune response to lung infection. Anat Rec (Hoboken) (2010) 1.06
Lung lining fluid glutathione attenuates IL-13-induced asthma. Am J Respir Cell Mol Biol (2007) 1.06
Synthesis and organization of hyaluronan and versican by embryonic stem cells undergoing embryoid body differentiation. J Histochem Cytochem (2009) 1.05
Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study. BMC Med Genet (2010) 1.04
Lung cancer susceptibility model based on age, family history and genetic variants. PLoS One (2009) 1.03
Comparison of different markers of socioeconomic status with cardiovascular disease and diabetes risk factors in the Diabetes, Heart and Health Survey. N Z Med J (2008) 1.03
Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix. J Biol Chem (2012) 1.02
The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit. J Biol Chem (2007) 1.02
Changes in perlecan expression during vascular injury: role in the inhibition of smooth muscle cell proliferation in the late lesion. Arterioscler Thromb Vasc Biol (2003) 1.01
Diabetes and arterial extracellular matrix changes in a porcine model of atherosclerosis. J Histochem Cytochem (2007) 1.01
V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis. Lab Invest (2006) 0.99
Neointima formed by arterial smooth muscle cells expressing versican variant V3 is resistant to lipid and macrophage accumulation. Arterioscler Thromb Vasc Biol (2011) 0.99
Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis. PLoS One (2009) 0.99
Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells. J Cell Sci (2006) 0.99
Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis. Circulation (2003) 0.98
miRNAs regulate expression and function of extracellular matrix molecules. Matrix Biol (2012) 0.98
Native fibrillar collagen membranes of micron-scale and submicron thicknesses for cell support and perfusion. Biomaterials (2005) 0.97
Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro. Am J Physiol Cell Physiol (2007) 0.97
Propagation and control of T cell responses by heparan sulfate-bound IL-2. J Immunol (2003) 0.96
The role of hyaluronan and the extracellular matrix in islet inflammation and immune regulation. Curr Diab Rep (2012) 0.96
Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican. Arterioscler Thromb Vasc Biol (2008) 0.95
Microgrooved fibrillar collagen membranes as scaffolds for cell support and alignment. Biomaterials (2005) 0.95
Matrix proteoglycans and remodelling of interstitial lung tissue in lymphangioleiomyomatosis. J Pathol (2004) 0.95
Smooth muscle cell biglycan overexpression results in increased lipoprotein retention on extracellular matrix: implications for the retention of lipoproteins in atherosclerosis. Atherosclerosis (2004) 0.95
Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse. Cell Mol Immunol (2010) 0.94
Increased plasmin and serine proteinase activity during flow-induced intimal atrophy in baboon PTFE grafts. Arterioscler Thromb Vasc Biol (2002) 0.94