Published in Am J Physiol Endocrinol Metab on May 20, 2008
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids. J Lipid Res (2009) 1.36
Exercise- and training-induced upregulation of skeletal muscle fatty acid oxidation are not solely dependent on mitochondrial machinery and biogenesis. J Physiol (2012) 1.14
Lack of adequate appreciation of physical exercise's complexities can pre-empt appropriate design and interpretation in scientific discovery. J Physiol (2009) 1.10
In vivo, fatty acid translocase (CD36) critically regulates skeletal muscle fuel selection, exercise performance, and training-induced adaptation of fatty acid oxidation. J Biol Chem (2012) 0.98
Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle. J Physiol (2013) 0.95
Lipidomics analysis reveals efficient storage of hepatic triacylglycerides enriched in unsaturated fatty acids after one bout of exercise in mice. PLoS One (2010) 0.93
Differential regulation of PGC-1alpha expression in rat liver and skeletal muscle in response to voluntary running. Nutr Metab (Lond) (2010) 0.79
The crucial role of ATGL for energy supply of muscles. J Lipid Res (2009) 0.77
Tissue taurine depletion alters metabolic response to exercise and reduces running capacity in mice. J Amino Acids (2014) 0.75
Fermented goat milk consumption during anaemia recovery: ergogenic effect and improvement of skeletal muscle homeostasis. Eur J Nutr (2016) 0.75
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes. Cell Metab (2012) 2.46
Adipocyte lipases and defect of lipolysis in human obesity. Diabetes (2005) 2.14
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets. Cell Metab (2012) 1.93
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes. Science (2009) 1.90
Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. PLoS Biol (2013) 1.87
Tissue-specific alternative splicing of TCF7L2. Hum Mol Genet (2009) 1.80
Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins. J Biol Chem (2009) 1.64
Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes. Diabetes (2012) 1.54
Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. J Clin Endocrinol Metab (2007) 1.54
Particle separation using ultrasound can radically reduce embolic load to brain after cardiac surgery. Ann Thorac Surg (2004) 1.50
Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces. Lab Chip (2004) 1.43
Effect of murine strain on metabolic pathways of glucose production after brief or prolonged fasting. Am J Physiol Endocrinol Metab (2005) 1.34
Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL. FASEB J (2009) 1.22
Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes. J Biol Chem (2003) 1.21
Endosperm and whole grain rye breads are characterized by low post-prandial insulin response and a beneficial blood glucose profile. Nutr J (2009) 1.21
Decrease in intramuscular lipid droplets and translocation of HSL in response to muscle contraction and epinephrine. J Lipid Res (2006) 1.20
Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells. J Physiol (2004) 1.20
Separation of lipids from blood utilizing ultrasonic standing waves in microfluidic channels. Analyst (2004) 1.18
Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact. J Biol Chem (2003) 1.15
Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane. Diabetes (2007) 1.15
Pleiotropic effects of GIP on islet function involve osteopontin. Diabetes (2011) 1.08
Metabolomic and proteomic analysis of a clonal insulin-producing beta-cell line (INS-1 832/13). J Proteome Res (2007) 1.03
Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway. Hum Mol Genet (2011) 1.03
Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels and elevation of cytoplasmic calcium. Diabetes (2004) 1.02
Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice. PLoS One (2008) 1.01
Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates. PLoS One (2008) 0.98
Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion. Diabetes (2004) 0.98
Hormone-sensitive lipase is a cholesterol esterase of the intestinal mucosa. J Biol Chem (2002) 0.98
Characterization of the lipid droplet proteome of a clonal insulin-producing β-cell line (INS-1 832/13). J Proteome Res (2012) 0.97
Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle. J Physiol (2013) 0.95
Link between GIP and osteopontin in adipose tissue and insulin resistance. Diabetes (2013) 0.92
Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area. FEBS J (2009) 0.90
Major gender differences in the lipolytic capacity of abdominal subcutaneous fat cells in obesity observed before and after long-term weight reduction. J Clin Endocrinol Metab (2002) 0.90
A unique defect in the regulation of visceral fat cell lipolysis in the polycystic ovary syndrome as an early link to insulin resistance. Diabetes (2002) 0.90
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. J Clin Invest (2015) 0.90
The testicular form of hormone-sensitive lipase HSLtes confers rescue of male infertility in HSL-deficient mice. J Biol Chem (2004) 0.89
Contractions activate hormone-sensitive lipase in rat muscle by protein kinase C and mitogen-activated protein kinase. J Physiol (2003) 0.88
Local and translational dynamics in DNA-lipid assemblies monitored by solid-state and diffusion NMR. Biochim Biophys Acta (2008) 0.88
Rye bran alkylresorcinols suppress adipocyte lipolysis and hormone-sensitive lipase activity. Mol Nutr Food Res (2011) 0.87
Contractions induce phosphorylation of the AMPK site Ser565 in hormone-sensitive lipase in muscle. Biochem Biophys Res Commun (2004) 0.86
Hormone-sensitive lipase as mediator of lipolysis in contracting skeletal muscle. Exerc Sport Sci Rev (2005) 0.86
Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact. Endocrinology (2004) 0.86
Characterization of a novel testicular form of human hormone-sensitive lipase. Biochem Biophys Res Commun (2002) 0.85
Perilipin is present in islets of Langerhans and protects against lipotoxicity when overexpressed in the beta-cell line INS-1. Endocrinology (2009) 0.85
EuroDia: a beta-cell gene expression resource. Database (Oxford) (2010) 0.84
A novel hormone-sensitive lipase isoform expressed in pancreatic beta-cells. J Biol Chem (2003) 0.84
C(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes. Diabetes (2002) 0.83
Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity. Diabetes (2013) 0.83
Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice. J Lipid Res (2005) 0.83
Rose hip exerts antidiabetic effects via a mechanism involving downregulation of the hepatic lipogenic program. Am J Physiol Endocrinol Metab (2010) 0.83
Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding. Biochem Biophys Res Commun (2003) 0.83
Metabolic effects of whole grain wheat and whole grain rye in the C57BL/6J mouse. Nutrition (2009) 0.82
Disturbed cholesterol homeostasis in hormone-sensitive lipase-null mice. Am J Physiol Endocrinol Metab (2008) 0.81
Subcellular distribution of spermidine/spermine N1-acetyltransferase. Cell Biol Int (2007) 0.81
Material characterization and in vivo behavior of silicon substituted alpha-tricalcium phosphate cement. J Biomed Mater Res B Appl Biomater (2006) 0.81
Relation between cycling exercise capacity, fiber-type composition, and lower extremity muscle strength and muscle endurance. J Strength Cond Res (2011) 0.81
Lack of cholesterol mobilization in islets of hormone-sensitive lipase deficient mice impairs insulin secretion. Biochem Biophys Res Commun (2008) 0.81
Simulation of the release from a multiparticulate system validated by single pellet and dose release experiments. J Control Release (2004) 0.81
Inflammatory response in white adipose tissue in the non-obese hormone-sensitive lipase null mouse model. J Proteome Res (2006) 0.81
Glucose-stimulated insulin secretion correlates with beta-cell lipolysis. Nutr Metab Cardiovasc Dis (2006) 0.81
The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins. J Clin Endocrinol Metab (2012) 0.81
Marked reutilization of free fatty acids during activated lipolysis in human skeletal muscle. J Clin Endocrinol Metab (2004) 0.81
Effects of growth hormone on the function of beta-adrenoceptor subtypes in rat adipocytes. Obes Res (2004) 0.81
Formation of carbonated apatite particles from a supersaturated inorganic blood serum model. J Mater Sci Mater Med (2009) 0.81
Regulation and role of hormone-sensitive lipase in rat skeletal muscle. Proc Nutr Soc (2004) 0.80
Diverse effects of oats on cholesterol metabolism in C57BL/6 mice correlate with expression of hepatic bile acid-producing enzymes. Eur J Nutr (2012) 0.79
Cereal byproducts have prebiotic potential in mice fed a high-fat diet. J Agric Food Chem (2014) 0.79
Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. PLoS One (2011) 0.79
[Serotonin syndrome. Several cases of this often overlooked diagnosis]. Lakartidningen (2002) 0.79
The presence of a catalytically inactive form of hormone-sensitive lipase is associated with decreased lipolysis in abdominal subcutaneous adipose tissue of obese subjects. Diabetes (2003) 0.78
Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase. Diabetes (2003) 0.77
HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13. PLoS One (2012) 0.76
The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes. Mol Genet Metab (2011) 0.76
Amino-terminal anchored surface display in insect cells and budded baculovirus using the amino-terminal end of neuraminidase. J Biotechnol (2004) 0.76
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. J Clin Invest (2016) 0.76
Proteomic studies in animal models of diabetes. Proteomics Clin Appl (2008) 0.75
Running with regulation. J Appl Physiol (1985) (2010) 0.75
Quarternary structure and enzymological properties of the different hormone-sensitive lipase (HSL) isoforms. PLoS One (2010) 0.75
Comparison of MS/MS methods for protein identification from 2D-PAGE. J Proteome Res (2006) 0.75
PP038. Renal ETK/BMX activation decreased in preeclampsia. Pregnancy Hypertens (2013) 0.75
Omics analyses reveal a potential link between hormone-sensitive lipase and polyamine metabolism. J Proteome Res (2009) 0.75
[Serotonin syndrome--several cases of this often overlooked diagnosis]. Tidsskr Nor Laegeforen (2002) 0.75