Published in J Lipid Res on November 25, 2009
Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog Lipid Res (2010) 2.60
Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase. J Biol Chem (2010) 1.64
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem (2011) 1.42
Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice. Nat Commun (2017) 1.39
Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats. J Physiol (2012) 1.37
Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling. Chem Rev (2011) 1.28
PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans. J Lipid Res (2012) 1.23
Exercise- and training-induced upregulation of skeletal muscle fatty acid oxidation are not solely dependent on mitochondrial machinery and biogenesis. J Physiol (2012) 1.14
Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes (2013) 1.06
Contribution of novel ATGL missense mutations to the clinical phenotype of NLSD-M: a strikingly low amount of lipase activity may preserve cardiac function. Hum Mol Genet (2012) 0.99
In vivo, fatty acid translocase (CD36) critically regulates skeletal muscle fuel selection, exercise performance, and training-induced adaptation of fatty acid oxidation. J Biol Chem (2012) 0.98
Adipose triglyceride lipase expression in human adipose tissue and muscle. Role in insulin resistance and response to training and pioglitazone. Metabolism (2010) 0.96
Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle. J Physiol (2013) 0.95
Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population. PLoS Genet (2010) 0.94
Lipidomics analysis reveals efficient storage of hepatic triacylglycerides enriched in unsaturated fatty acids after one bout of exercise in mice. PLoS One (2010) 0.93
Skeletal muscle lipid flux: running water carries no poison. Am J Physiol Endocrinol Metab (2011) 0.91
A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity. J Biol Chem (2014) 0.91
Cardiac oxidative stress in a mouse model of neutral lipid storage disease. Biochim Biophys Acta (2013) 0.90
The role of triglyceride lipases in cancer associated cachexia. Trends Mol Med (2013) 0.88
Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption. Am J Physiol Gastrointest Liver Physiol (2012) 0.88
Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A. Biochim Biophys Acta (2014) 0.88
Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice. Am J Transl Res (2013) 0.85
Pleiotropic regulation of mitochondrial function by adipose triglyceride lipase-mediated lipolysis. Biochimie (2013) 0.83
Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity. Proc Natl Acad Sci U S A (2015) 0.81
Higher levels of ATGL are associated with exercise-induced enhancement of lipolysis in rat epididymal adipocytes. PLoS One (2012) 0.81
Carbenoxolone treatment ameliorated metabolic syndrome in WNIN/Ob obese rats, but induced severe fat loss and glucose intolerance in lean rats. PLoS One (2012) 0.80
Comparative gene identification-58/α/β hydrolase domain 5: more than just an adipose triglyceride lipase activator? Curr Opin Lipidol (2014) 0.80
Lipolytic signaling in response to acute exercise is altered in female mice following ovariectomy. J Cell Biochem (2011) 0.80
Physiological Consequences of Compartmentalized Acyl-CoA Metabolism. J Biol Chem (2015) 0.79
Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice. Biochim Biophys Acta (2012) 0.78
Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate. J Biol Chem (2015) 0.78
The crucial role of ATGL for energy supply of muscles. J Lipid Res (2009) 0.77
Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice. Am J Physiol Endocrinol Metab (2015) 0.76
The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells. J Obes (2015) 0.75
Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics. J Diabetes Res (2015) 0.75
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science (2004) 8.58
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science (2006) 7.35
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab (2006) 6.25
Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J Biol Chem (2006) 3.74
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J Clin Invest (2008) 3.25
The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy. Nat Genet (2006) 3.17
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J Biol Chem (2001) 3.10
A comparison of three methods of glycogen measurement in tissues. Anal Biochem (1974) 2.83
Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome. Am J Hum Genet (2001) 2.72
Lipolysis: pathway under construction. Curr Opin Lipidol (2005) 2.32
Skeletal muscle lipid metabolism in exercise and insulin resistance. Physiol Rev (2006) 2.15
Molecular mechanisms regulating hormone-sensitive lipase and lipolysis. Biochem Soc Trans (2003) 2.11
Neutral-lipid storage disease: a new disorder of lipid metabolism. Br Med J (1975) 1.97
Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes. J Biol Chem (2009) 1.93
The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding. J Biol Chem (2008) 1.80
Ichthyosiform dermatosis with systemic lipidosis. Arch Dermatol (1974) 1.69
Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice. Am J Physiol Endocrinol Metab (2009) 1.62
Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol. Biochim Biophys Acta (1986) 1.45
Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training. Am J Physiol Endocrinol Metab (2008) 1.33
The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets. J Clin Endocrinol Metab (2008) 1.28
Stimulation of hormone-sensitive lipase activity by contractions in rat skeletal muscle. Biochem J (2000) 1.21
Decrease in intramuscular lipid droplets and translocation of HSL in response to muscle contraction and epinephrine. J Lipid Res (2006) 1.20
Novel duplication mutation in the patatin domain of adipose triglyceride lipase (PNPLA2) in neutral lipid storage disease with severe myopathy. Muscle Nerve (2007) 1.15
Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and high-density lipoprotein-cholesterol levels. Proc Natl Acad Sci U S A (1999) 1.06
Energy state of the liver during short-term and exhaustive exercise in C57BL/6J mice. Am J Physiol Endocrinol Metab (2005) 1.05
Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific. Histochem Cell Biol (2008) 0.98
The multifunctional role of hormone-sensitive lipase in lipid metabolism. Adv Enzyme Regul (1994) 0.97
Effects of dynamic exercise intensity on the activation of hormone-sensitive lipase in human skeletal muscle. J Physiol (2002) 0.97
Regulatory mechanisms in the interaction between carbohydrate and lipid oxidation during exercise. Acta Physiol Scand (2003) 0.96
Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise. Am J Physiol Endocrinol Metab (2008) 0.93
Hormone-sensitive lipase as mediator of lipolysis in contracting skeletal muscle. Exerc Sport Sci Rev (2005) 0.86
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science (2004) 8.58
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science (2006) 7.35
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab (2006) 6.25
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue. J Clin Invest (2010) 4.56
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat Med (2011) 3.96
Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J Biol Chem (2006) 3.74
Adipose triglyceride lipase contributes to cancer-associated cachexia. Science (2011) 3.70
Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. J Lipid Res (2008) 3.35
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J Biol Chem (2001) 3.10
FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling. Cell Metab (2012) 2.96
Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism. Curr Opin Lipidol (2002) 2.85
Cellular fatty acid metabolism and cancer. Cell Metab (2013) 2.82
Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog Lipid Res (2010) 2.60
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. Hepatology (2011) 2.33
Klebsiella oxytoca as a causative organism of antibiotic-associated hemorrhagic colitis. N Engl J Med (2006) 2.33
Lipolysis: pathway under construction. Curr Opin Lipidol (2005) 2.32
Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. Am J Physiol Endocrinol Metab (2009) 2.19
Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. J Biol Chem (2005) 2.11
AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise. Proc Natl Acad Sci U S A (2011) 1.96
Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions. J Lipid Res (2008) 1.95
Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis. J Biol Chem (2008) 1.94
The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding. J Biol Chem (2008) 1.80
Alteration of intestinal dysbiosis by fecal microbiota transplantation does not induce remission in patients with chronic active ulcerative colitis. Inflamm Bowel Dis (2013) 1.79
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome. J Lipid Res (2010) 1.75
Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58). J Biol Chem (2009) 1.72
Evaluation of high-resolution melting analysis as a diagnostic tool to detect the BRAF V600E mutation in colorectal tumors. J Mol Diagn (2009) 1.72
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. Cell Metab (2012) 1.71
Species-specific identification of campylobacters by partial 16S rRNA gene sequencing. J Clin Microbiol (2003) 1.70
The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance. Cell Metab (2012) 1.66
Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase. Proc Natl Acad Sci U S A (2003) 1.65
Fate of fat: the role of adipose triglyceride lipase in lipolysis. Biochim Biophys Acta (2008) 1.64
Brain insulin controls adipose tissue lipolysis and lipogenesis. Cell Metab (2011) 1.64
Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling. J Biol Chem (2009) 1.63