Published in J Neurochem on May 26, 2008
Aberrant protein s-nitrosylation in neurodegenerative diseases. Neuron (2013) 1.55
S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide. Proc Natl Acad Sci U S A (2011) 1.21
Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs. Cell Cycle (2012) 1.04
Surgical incision-induced nociception causes cognitive impairment and reduction in synaptic NMDA receptor 2B in mice. J Neurosci (2013) 1.01
The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (2009) 1.00
p10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity. Proc Natl Acad Sci U S A (2012) 0.98
Cdk5 activity in the brain - multiple paths of regulation. J Cell Sci (2014) 0.95
Sigma-1 receptor regulates Tau phosphorylation and axon extension by shaping p35 turnover via myristic acid. Proc Natl Acad Sci U S A (2015) 0.93
Physiological and pathological phosphorylation of tau by Cdk5. Front Mol Neurosci (2014) 0.91
Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse. Nat Neurosci (2011) 0.89
Phosphorylation of drebrin by cyclin-dependent kinase 5 and its role in neuronal migration. PLoS One (2014) 0.86
Phosphorylation of AATYK1 by Cdk5 suppresses its tyrosine phosphorylation. PLoS One (2010) 0.84
Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. J Biol Chem (2013) 0.83
N-myristoylated proteins, key components in intracellular signal transduction systems enabling rapid and flexible cell responses. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.83
Why cyclin Y? A highly conserved cyclin with essential functions. Fly (Austin) (2010) 0.82
S-nitrosylation of Cdk5: potential implications in amyloid-β-related neurotoxicity in Alzheimer disease. Prion (2012) 0.81
Bioinformatic prediction and confirmation of beta-adducin as a novel substrate of glycogen synthase kinase 3. J Biol Chem (2011) 0.81
Cyclin I is involved in the regulation of cell cycle progression. Cell Cycle (2013) 0.81
A novel effect of MARCKS phosphorylation by activated PKC: the dephosphorylation of its serine 25 in chick neuroblasts. PLoS One (2013) 0.78
Stress-induced nuclear translocation of CDK5 suppresses neuronal death by downregulating ERK activation via VRK3 phosphorylation. Sci Rep (2016) 0.78
Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5. J Biol Chem (2014) 0.78
Structural basis for the different stability and activity between the Cdk5 complexes with p35 and p39 activators. J Biol Chem (2013) 0.77
A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5. Mol Neurobiol (2016) 0.76
Two Degradation Pathways of the p35 Cdk5 (Cyclin-dependent Kinase) Activation Subunit, Dependent and Independent of Ubiquitination. J Biol Chem (2015) 0.76
p35 regulates the CRM1-dependent nucleocytoplasmic shuttling of nuclear hormone receptor coregulator-interacting factor 1 (NIF-1). PLoS One (2014) 0.76
Cdk5 links with DNA damage response and cancer. Mol Cancer (2017) 0.75
Myristic acid hitchhiking on sigma-1 receptor to fend off neurodegeneration. Receptors Clin Investig (2016) 0.75
Effects of p35 Mutations Associated with Mental Retardation on the Cellular Function of p35-CDK5. PLoS One (2015) 0.75
Cyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulation. Sci Rep (2017) 0.75
Decreasing Levels of the cdk5 Activators, p25 and p35, Reduces Excitotoxicity in Striatal Neurons. J Huntingtons Dis (2012) 0.75
Neuronal networks in mental diseases and neuropathic pain: Beyond brain derived neurotrophic factor and collapsin response mediator proteins. World J Psychiatry (2016) 0.75
The Rice Annotation Project Database (RAP-DB): 2008 update. Nucleic Acids Res (2007) 4.23
Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana. Genome Res (2007) 3.13
Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites. Science (2008) 3.10
The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res (2007) 2.07
Risk Stratification of Coronary Artery Disease in Asymptomatic Diabetic Subjects Using Multidetector Computed Tomography. Circ J (2015) 1.99
Protein structure determination in living cells by in-cell NMR spectroscopy. Nature (2009) 1.71
Cophosphorylation of amphiphysin I and dynamin I by Cdk5 regulates clathrin-mediated endocytosis of synaptic vesicles. J Cell Biol (2003) 1.65
A mammalian neural tissue opsin (Opsin 5) is a deep brain photoreceptor in birds. Proc Natl Acad Sci U S A (2010) 1.48
Distinct migratory behavior of early- and late-born neurons derived from the cortical ventricular zone. J Comp Neurol (2004) 1.47
MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins. Genome Biol (2004) 1.42
Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia. Neuropsychopharmacology (2013) 1.33
Conversion of wild-type alpha-synuclein into mutant-type fibrils and its propagation in the presence of A30P mutant. J Biol Chem (2009) 1.29
Does reconstruction of posterior ligamentous complex with extensor musculature decrease axial symptoms after cervical laminoplasty? Spine (Phila Pa 1976) (2002) 1.27
Comprehensive screening for antigens overexpressed on carcinomas via isolation of human mAbs that may be therapeutic. Proc Natl Acad Sci U S A (2008) 1.21
Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development. Mol Cell Biol (2007) 1.21
Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability. J Neurochem (2005) 1.20
Demonstration of a role for alpha-synuclein as a functional microtubule-associated protein. J Alzheimers Dis (2004) 1.19
Comparative expression analysis uncovers novel features of endogenous antisense transcription. Hum Mol Genet (2008) 1.18
Methods for comprehensive identification of membrane proteins recognized by a large number of monoclonal antibodies. J Immunol Methods (2009) 1.15
Comprehensive clarification of two paralogous interleukin 4/13 loci in teleost fish. Immunogenetics (2008) 1.13
Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies. FEBS Lett (2007) 1.12
Effect of milk fermented with Lactobacillus acidophilus strain L-92 on symptoms of Japanese cedar pollen allergy: a randomized placebo-controlled trial. Biosci Biotechnol Biochem (2005) 1.10
Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis. PLoS One (2010) 1.10
Impairment of hippocampal long-term depression and defective spatial learning and memory in p35 mice. J Neurochem (2005) 1.09
Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau. J Biol Chem (2002) 1.09
Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease. J Neurosci (2012) 1.08
Tau phosphorylation by cyclin-dependent kinase 5/p39 during brain development reduces its affinity for microtubules. J Biol Chem (2003) 1.07
Atg9 vesicles recruit vesicle-tethering proteins Trs85 and Ypt1 to the autophagosome formation site. J Biol Chem (2012) 1.07
Regulation of endothelial nitric oxide synthase by protein kinase C. J Biochem (2003) 1.07
Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually dimorphic kisspeptin neurons in medaka (oryzias latipes). Endocrinology (2008) 1.05
Quantitative measurement of in vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE. Mol Cell Proteomics (2010) 1.03
Re-expression of CEACAM1 long cytoplasmic domain isoform is associated with invasion and migration of colorectal cancer. Int J Cancer (2011) 1.02
The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator. Neurosignals (2003) 1.02
Enhanced activation of Ca2+/calmodulin-dependent protein kinase II upon downregulation of cyclin-dependent kinase 5-p35. J Neurosci Res (2006) 1.01
Inhibition of alpha-synuclein fibril assembly by small molecules: analysis using epitope-specific antibodies. FEBS Lett (2009) 1.00
CDK5-dependent phosphorylation of the Rho family GTPase TC10(alpha) regulates insulin-stimulated GLUT4 translocation. J Biol Chem (2008) 0.99
Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo. Protein Sci (2005) 0.98
Suppression of calpain-dependent cleavage of the CDK5 activator p35 to p25 by site-specific phosphorylation. J Biol Chem (2006) 0.98
Membrane association facilitates degradation and cleavage of the cyclin-dependent kinase 5 activators p35 and p39. Biochemistry (2010) 0.96
Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E. Hum Mol Genet (2010) 0.95
Usefulness of the Corsair microcatheter for treatment of complex chronic total occlusion. J Invasive Cardiol (2012) 0.95
LMTK1/AATYK1 is a novel regulator of axonal outgrowth that acts via Rab11 in a Cdk5-dependent manner. J Neurosci (2012) 0.95
14-3-3 Mediates phosphorylation-dependent inhibition of the interaction between the ubiquitin E3 ligase Nedd4-2 and epithelial Na+ channels. Biochemistry (2006) 0.93
Hypertrophy and loss of podocytes in diabetic nephropathy. Intern Med (2009) 0.92
Genome-wide analysis of expression modes and DNA methylation status at sense-antisense transcript loci in mouse. Genomics (2010) 0.92
Suppression of mutant Huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability. J Neurosci (2008) 0.92
Site-selective post-translational modification of proteins using an unnatural amino acid, 3-azidotyrosine. J Biochem (2007) 0.92
Phosphorylation of p35 and p39 by Cdk5 determines the subcellular location of the holokinase in a phosphorylation-site-specific manner. J Cell Sci (2012) 0.92
Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme. Biochem Biophys Res Commun (2011) 0.91
Cdk5--p39 is a labile complex with the similar substrate specificity to Cdk5--p35. J Neurochem (2007) 0.91
Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25. J Neurochem (2011) 0.91
Effects of liraglutide, a human glucagon-like peptide-1 analogue, on body weight, body fat area and body fat-related markers in patients with type 2 diabetes mellitus. Intern Med (2013) 0.90
Rectal transection by the Nelaton catheter pulling method during a laparoscopic low anterior resection. Dis Colon Rectum (2011) 0.90
Decrease in ovalbumin specific IgE of mice serum after oral uptake of lactic acid bacteria. Biosci Biotechnol Biochem (2003) 0.89
Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure. BMC Struct Biol (2008) 0.89
Diversity of brain morphology in teleosts: brain and ecological niche. Brain Behav Evol (2007) 0.89
Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule. Amino Acids (2009) 0.88
Activation of latent cyclin-dependent kinase 5 (Cdk5)-p35 complexes by membrane dissociation. J Neurochem (2005) 0.88
Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants. Hum Mol Genet (2006) 0.88
The saccus vasculosus of fish is a sensor of seasonal changes in day length. Nat Commun (2013) 0.88
Developmental origin of diencephalic sensory relay nuclei in teleosts. Brain Behav Evol (2007) 0.88
Phosphorylation of adult type Sept5 (CDCrel-1) by cyclin-dependent kinase 5 inhibits interaction with syntaxin-1. J Biol Chem (2007) 0.87
NMR protein structure determination in living E. coli cells using nonlinear sampling. Nat Protoc (2010) 0.87
Non-laminar cerebral cortex in teleost fishes? Biol Lett (2009) 0.86
Molecular mechanism for pterin-mediated inactivation of tyrosine hydroxylase: formation of insoluble aggregates of tyrosine hydroxylase. J Biochem (2006) 0.86
In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta. J Biol Chem (2002) 0.86
Regulation of the interaction of Disabled-1 with CIN85 by phosphorylation with Cyclin-dependent kinase 5. Genes Cells (2007) 0.85
Antihypertensive effect of casein hydrolysate in a placebo-controlled study in subjects with high-normal blood pressure and mild hypertension. Br J Nutr (2005) 0.85
Phosphorylation of FTDP-17 mutant tau by cyclin-dependent kinase 5 complexed with p35, p25, or p39. J Biol Chem (2005) 0.85
Solubilisation of [60]fullerenes using block copolymers and evaluation of their photodynamic activities. Org Biomol Chem (2008) 0.85
Efficacy of long-acting insulin analog insulin glargine at high dosage for basal-bolus insulin therapy in patients with type 2 diabetes. Tokai J Exp Clin Med (2012) 0.85
Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus). Proc Natl Acad Sci U S A (2011) 0.85
Study of the mechanism of antihypertensive peptides VPP and IPP in spontaneously hypertensive rats by DNA microarray analysis. Eur J Pharmacol (2009) 0.85
Relationships of stress responses with plasma oxytocin and prolactin in heifer calves. Physiol Behav (2009) 0.85
Anti-influenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity. Br J Nutr (2013) 0.84
Small molecule inhibitor of type I transforming growth factor-β receptor kinase ameliorates the inhibitory milieu in injured brain and promotes regeneration of nigrostriatal dopaminergic axons. J Neurosci Res (2010) 0.84
Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. J Biol Chem (2013) 0.83
Regulation of membrane association and kinase activity of Cdk5-p35 by phosphorylation of p35. J Neurosci Res (2007) 0.83
Periventricular efferent neurons in the optic tectum of rainbow trout. J Comp Neurol (2006) 0.83
Bowline mediates association of the transcriptional corepressor XGrg-4 with Tbx6 during somitogenesis in Xenopus. Biochem Biophys Res Commun (2007) 0.83
Suppression of fibrotic scar formation promotes axonal regeneration without disturbing blood-brain barrier repair and withdrawal of leukocytes after traumatic brain injury. J Comp Neurol (2010) 0.83
Axonogenesis in the medaka embryonic brain. J Comp Neurol (2004) 0.83
The astrocytic lineage marker calmodulin-regulated spectrin-associated protein 1 (Camsap1): phenotypic heterogeneity of newly born Camsap1-expressing cells in injured mouse brain. J Comp Neurol (2012) 0.83
Casein hydrolysate containing Val-Pro-Pro and Ile-Pro-Pro improves central blood pressure and arterial stiffness in hypertensive subjects: a randomized, double-blind, placebo-controlled trial. Atherosclerosis (2011) 0.83
Polymorphism of two very similar MHC class Ib loci in rainbow trout (Oncorhynchus mykiss). Immunogenetics (2006) 0.83
Topographical organization of an indirect telencephalo-cerebellar pathway through the nucleus paracommissuralis in a teleost, Oreochromis niloticus. Brain Behav Evol (2003) 0.83
Solution X-ray scattering reveals a novel structure of calmodulin complexed with a binding domain peptide from the HIV-1 matrix protein p17. Biochemistry (2008) 0.83
Morphogenesis and regionalization of the medaka embryonic brain. J Comp Neurol (2004) 0.82