Structural and functional characterization of transmembrane segment IX of the NHE1 isoform of the Na+/H+ exchanger.

Plant NHX cation/proton antiporters. Plant Signal Behav (2009) 1.21

Model-guided mutagenesis drives functional studies of human NHA2, implicated in hypertension. J Mol Biol (2010) 0.95

Headgroup-dependent membrane catalysis of apelin-receptor interactions is likely. J Phys Chem B (2009) 0.85

Structural and functional analysis of transmembrane segment VI of the NHE1 isoform of the Na+/H+ exchanger. J Biol Chem (2010) 0.82

Structural and functional analysis of transmembrane XI of the NHE1 isoform of the Na+/H+ exchanger. J Biol Chem (2009) 0.82

Description of local and global shape properties of protein helices. J Mol Model (2013) 0.80

Determinants of Cation Permeation and Drug Sensitivity in Predicted Transmembrane Helix 9 and Adjoining Exofacial Re-entrant Loop 5 of Na+/H+ Exchanger NHE1. J Biol Chem (2015) 0.75

Structural and functional analysis of transmembrane segment IV of the salt tolerance protein Sod2. J Biol Chem (2013) 0.75

HMDB: the Human Metabolome Database. Nucleic Acids Res (2007) 13.38

VADAR: a web server for quantitative evaluation of protein structure quality. Nucleic Acids Res (2003) 3.95

Melamine-contaminated powdered formula and urolithiasis in young children. N Engl J Med (2009) 3.46

Survival prediction of gastric cancer by a seven-microRNA signature. Gut (2009) 2.37

Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer. J Clin Oncol (2010) 2.16

Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. Anal Chem (2007) 2.15

miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3. Mol Cancer Res (2011) 2.00

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2. Hepatology (2010) 1.88

Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells. Int J Cancer (2008) 1.88

MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma. Hepatology (2010) 1.82

Use of ionic liquids for pi-conjugated polymer electrochemical devices. Science (2002) 1.66

DNA binding: a novel function of Pseudomonas aeruginosa type IV pili. J Bacteriol (2005) 1.64

Peroxisome proliferator-activated receptor-α is renoprotective in doxorubicin-induced glomerular injury. Kidney Int (2011) 1.59

Structural based insights into the role of troponin in cardiac muscle pathophysiology. J Muscle Res Cell Motil (2005) 1.53

Expert guidelines for the management of Alport syndrome and thin basement membrane nephropathy. J Am Soc Nephrol (2013) 1.52

Effect of intravenous proton pump inhibitor regimens and timing of endoscopy on clinical outcomes of peptic ulcer bleeding. J Gastroenterol Hepatol (2012) 1.51

Over-expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca2+ and RhoA activation. Exp Biol Med (Maywood) (2011) 1.47

Structural and functional analysis of the Na+/H+ exchanger. Biochem J (2007) 1.40

Up-regulation of tumor suppressor genes might promote the malignant phenotype of cancer cells. Med Hypotheses (2007) 1.39

Effects of low concentrations of benzene exposure on levels of platelet-associated antibodies and platelet parameters. J Occup Environ Med (2014) 1.38

Hypoxia-inducible microRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma. Hepatology (2011) 1.36

Toll-like receptors expressed by dermal fibroblasts contribute to hypertrophic scarring. J Cell Physiol (2011) 1.36

A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA. Nucleic Acids Res (2009) 1.34

The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions. Biochemistry (2002) 1.33

MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma. PLoS One (2012) 1.29

MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions. Nucleic Acids Res (2010) 1.29

Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger. J Biol Chem (2002) 1.28

Integration of ranked lists via cross entropy Monte Carlo with applications to mRNA and microRNA Studies. Biometrics (2008) 1.27

Structural basis for the conformational adaptability of apolipophorin III, a helix-bundle exchangeable apolipoprotein. Proc Natl Acad Sci U S A (2002) 1.25

An interplay between protein disorder and structure confers the Ca2+ regulation of striated muscle. J Mol Biol (2006) 1.25

Estimation of sequencing error rates in short reads. BMC Bioinformatics (2012) 1.22

Smartnotebook: a semi-automated approach to protein sequential NMR resonance assignments. J Biomol NMR (2003) 1.21

Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF. PLoS One (2012) 1.20

MicroRNA-423 promotes cell growth and regulates G(1)/S transition by targeting p21Cip1/Waf1 in hepatocellular carcinoma. Carcinogenesis (2011) 1.19

Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil. J Biol Chem (2002) 1.19

Molecular basis of therapeutic approaches to gastric cancer. J Gastroenterol Hepatol (2009) 1.18

Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative. Pediatr Nephrol (2012) 1.17

In situ orientations of protein domains: troponin C in skeletal muscle fibers. Mol Cell (2003) 1.17

Physiological role and regulation of the Na+/H+ exchanger. Can J Physiol Pharmacol (2006) 1.16

MicroRNA-107, an oncogene microRNA that regulates tumour invasion and metastasis by targeting DICER1 in gastric cancer. J Cell Mol Med (2011) 1.15

CoGAPS: an R/C++ package to identify patterns and biological process activity in transcriptomic data. Bioinformatics (2010) 1.15

Differential display of vincristine-resistance-related genes in gastric cancer SGC7901 cell. World J Gastroenterol (2002) 1.15

Characterizing ionic liquids on the basis of multiple solvation interactions. J Am Chem Soc (2002) 1.14

Mitogen-activated protein kinase-dependent activation of the Na+/H+ exchanger is mediated through phosphorylation of amino acids Ser770 and Ser771. J Biol Chem (2007) 1.13

Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation. Biochemistry (2012) 1.11

Modulation of cardiac troponin C function by the cardiac-specific N-terminus of troponin I: influence of PKA phosphorylation and involvement in cardiomyopathies. J Mol Biol (2007) 1.11

A novel carbonic anhydrase II binding site regulates NHE1 activity. Biochemistry (2006) 1.11

Visual impairment, age-related eye diseases, and cognitive function: the Singapore Malay Eye study. Arch Ophthalmol (2012) 1.10

Dynamics of the C-terminal region of TnI in the troponin complex in solution. Biophys J (2006) 1.10

Cold survival in freeze-intolerant insects: the structure and function of beta-helical antifreeze proteins. Eur J Biochem (2004) 1.09

Improved helix and kink characterization in membrane proteins allows evaluation of kink sequence predictors. J Chem Inf Model (2010) 1.08

Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate. J Biol Chem (2009) 1.08

Stem cell therapy for Alport syndrome: the hope beyond the hype. Nephrol Dial Transplant (2008) 1.07

TRPC6 up-regulation in Ang II-induced podocyte apoptosis might result from ERK activation and NF-kappaB translocation. Exp Biol Med (Maywood) (2009) 1.07

Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis. Cancer Res (2013) 1.06

Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate. J Biol Chem (2007) 1.06

Elimination of systematic mass measurement errors in liquid chromatography-mass spectrometry based proteomics using regression models and a priori partial knowledge of the sample content. Anal Chem (2007) 1.06

Internal pH indicators for biomolecular NMR. J Biomol NMR (2008) 1.05

Structure and function of the NHE1 isoform of the Na+/H+ exchanger. Biochem Cell Biol (2002) 1.05

Direct effect of croton oil on intestinal epithelial cells and colonic smooth muscle cells. World J Gastroenterol (2002) 1.05

Structural and functional cerebral impairments in cirrhotic patients with a history of overt hepatic encephalopathy. Eur J Radiol (2011) 1.03

NMR structure of a bifunctional rhodamine labeled N-domain of troponin C complexed with the regulatory "switch" peptide from troponin I: implications for in situ fluorescence studies in muscle fibers. Biochemistry (2003) 1.02

Structure and function of the human Na+/H+ exchanger isoform 1. Channels (Austin) (2011) 1.02

Interaction of cardiac troponin with cardiotonic drugs: a structural perspective. Biochem Biophys Res Commun (2007) 1.01

Backbone dynamics of SDF-1alpha determined by NMR: interpretation in the presence of monomer-dimer equilibrium. Protein Sci (2006) 1.01

A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex. J Mol Cell Cardiol (2010) 1.00

Metabolomic profiling of asthma: diagnostic utility of urine nuclear magnetic resonance spectroscopy. J Allergy Clin Immunol (2011) 0.98

Human hypertrophic scar-like nude mouse model: characterization of the molecular and cellular biology of the scar process. Wound Repair Regen (2011) 0.98

The molecular mechanism of hypertrophic scar. J Cell Commun Signal (2013) 0.97

Optimising the incorporation and release of a neurotrophic factor using conducting polypyrrole. J Control Release (2006) 0.97

Human enterovirus 71 uncoating captured at atomic resolution. J Virol (2013) 0.97

H(2)O(2)-induced Ca(2+) overload in NRVM involves ERK1/2 MAP kinases: role for an NHE-1-dependent pathway. Am J Physiol Heart Circ Physiol (2002) 0.97

Spruce budworm antifreeze protein: changes in structure and dynamics at low temperature. J Mol Biol (2003) 0.96

Kinetic studies of calcium and cardiac troponin I peptide binding to human cardiac troponin C using NMR spectroscopy. Eur Biophys J (2002) 0.96

Identification of the ice-binding face of antifreeze protein from Tenebrio molitor. FEBS Lett (2002) 0.96

The binding of W7, an inhibitor of striated muscle contraction, to cardiac troponin C. Biochemistry (2005) 0.95

Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis. Cancer (2012) 0.95

Effect of the knockdown of podocin mRNA on nephrin and alpha-actinin in mouse podocyte. Exp Biol Med (Maywood) (2004) 0.94

Aldosterone increases NHE-1 expression and induces NHE-1-dependent hypertrophy in neonatal rat ventricular myocytes. Hypertension (2003) 0.94

Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells. FEBS J (2009) 0.94

Optimization of culture conditions for hydrogen production by Ethanoligenens harbinense B49 using response surface methodology. Bioresour Technol (2008) 0.94

Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis. Int J Cancer (2009) 0.93

Retinal vessel caliber and lifelong neuropsychological functioning: retinal imaging as an investigative tool for cognitive epidemiology. Psychol Sci (2013) 0.93

The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. Biochemistry (2008) 0.93

Antigen retrieval with protease digestion applied in immunohistochemical diagnosis of Alport syndrome. Nephrol Dial Transplant (2008) 0.93

Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger. J Biol Chem (2005) 0.93

MAD2 as a key component of mitotic checkpoint: A probable prognostic factor for gastric cancer. Am J Clin Pathol (2009) 0.92

GNAI1 Suppresses Tumor Cell Migration and Invasion and is Post-Transcriptionally Regulated by Mir-320a/c/d in Hepatocellular Carcinoma. Cancer Biol Med (2012) 0.92

Expression and significances of Id1 helix-loop-helix protein overexpression in gastric cancer. Cancer Lett (2004) 0.92

Defining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complex. Biochemistry (2008) 0.92

Proline residues in transmembrane segment IV are critical for activity, expression and targeting of the Na+/H+ exchanger isoform 1. Biochem J (2004) 0.92

Detection of parent-of-origin effects using general pedigree data. Genet Epidemiol (2010) 0.92

Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin. Tumour Biol (2010) 0.92

Mutations in NPHS2 in sporadic steroid-resistant nephrotic syndrome in Chinese children. Nephrol Dial Transplant (2005) 0.92

Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth. J Biol Chem (2011) 0.91