Published in Am J Physiol Regul Integr Comp Physiol on May 28, 2008
Intrinsic sex-specific differences in microvascular endothelial cell phosphodiesterases. Am J Physiol Heart Circ Physiol (2010) 1.10
Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. Physiol Genomics (2010) 0.76
Vascular dysfunction precedes hypertension associated with a blood pressure locus on rat chromosome 12. Am J Physiol Heart Circ Physiol (2014) 0.75
Genetic Regulation of Endothelial Vasomotor Function. Front Physiol (2016) 0.75
The sex-specific genetic architecture of quantitative traits in humans. Nat Genet (2006) 4.93
Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular coronary disease. J Am Coll Cardiol (2006) 3.25
Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension (2001) 1.99
New target regions for human hypertension via comparative genomics. Genome Res (2000) 1.75
Menopause and cardiovascular disease: the evidence. Climacteric (2007) 1.60
Gender-specific care of the patient with diabetes: review and recommendations. Gend Med (2006) 1.59
Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat. Physiol Genomics (2007) 1.57
Consomic rat model systems for physiological genomics. Acta Physiol Scand (2004) 1.50
Altered structure and reduced distensibility of arteries in Dahl salt-sensitive rats. J Hypertens (2003) 1.44
Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. Physiol Genomics (2003) 1.37
A lower ratio of AT1/AT2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats. Cardiovasc Res (2004) 1.32
Endogenous estrogen attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction: the effects of sex and menstrual cycle. Am J Physiol Endocrinol Metab (2007) 1.19
High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries. Am J Physiol Heart Circ Physiol (2002) 1.19
Vasodilator dysfunction in aged spontaneously hypertensive rats: changes in NO synthase III and soluble guanylyl cyclase expression, and in superoxide anion production. Cardiovasc Res (1998) 1.18
Endothelium-dependent vasodilation in hypertension: a review. Blood Press (2000) 1.17
Role of gender in heart failure with normal left ventricular ejection fraction. Prog Cardiovasc Dis (2006) 1.10
Sexual dimorphism in oxidant status in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2006) 1.10
Introgression of chromosome 13 in Dahl salt-sensitive genetic background restores cerebral vascular relaxation. Am J Physiol Heart Circ Physiol (2004) 1.06
Altered vascular reactivity in mice made hypertensive by nitric oxide synthase inhibition. J Cardiovasc Pharmacol (2005) 1.05
Sex difference in development of diabetes and cardiovascular disease on the way from obesity and metabolic syndrome. Metabolism (2005) 1.02
Loss of endothelium and receptor-mediated dilation in pial arterioles of rats fed a short-term high salt diet. Hypertension (1999) 1.01
Ovarian hormones modulate endothelin-1 vascular reactivity and mRNA expression in DOCA-salt hypertensive rats. Hypertension (2001) 0.99
Attenuated vasoconstrictor responses to endothelin in afferent arterioles during a high-salt diet. Am J Physiol Renal Physiol (2007) 0.98
Response of resistance arteries to reduced PO2 and vasodilators during hypertension and elevated salt intake. Am J Physiol (1997) 0.98
Restoration of normal vascular relaxation mechanisms in cerebral arteries by chromosomal substitution in consomic SS.13BN rats. Am J Physiol Heart Circ Physiol (2005) 0.95
Gender differences in Ca(2+) entry mechanisms of vasoconstriction in Wistar-Kyoto and spontaneously hypertensive rats. Hypertension (1999) 0.95
Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. Physiol Genomics (2006) 0.93
Influence of female sex hormones on endothelium-derived vasoconstrictor prostanoid generation in microvessels of spontaneously hypertensive rats. Hypertension (1999) 0.93
Congenic strains reveal the effect of the renin gene on skeletal muscle angiogenesis induced by electrical stimulation. Physiol Genomics (2008) 0.92
Effect of dietary salt on arteriolar nitric oxide in striated muscle of normotensive rats. Am J Physiol (1993) 0.92
Effects of high-salt diet on CYP450-4A omega-hydroxylase expression and active tone in mesenteric resistance arteries. Am J Physiol Heart Circ Physiol (2004) 0.92
Overview of physiology, vascular biology, and mechanisms of hypertension. J Manag Care Pharm (2007) 0.91
Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population. Curr Allergy Asthma Rep (2006) 0.91
Cyclo-oxygenase-2, endothelium and aortic reactivity during deoxycorticosterone acetate salt-induced hypertension. J Hypertens (2005) 0.91
Sex differences and the effects of sex hormones on hemostasis and vascular reactivity. Heart Lung (2001) 0.89
Alterations in structure and mechanics of resistance arteries from ouabain-induced hypertensive rats. Am J Physiol Heart Circ Physiol (2006) 0.89
Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. Genes Brain Behav (2006) 0.88
The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in nonobese diabetic mice. Diabetes (2006) 0.86
High-salt diet impairs hypoxia-induced cAMP production and hyperpolarization in rat skeletal muscle arteries. Am J Physiol Heart Circ Physiol (2001) 0.86
Estrogen potentiates vasopressin-induced contraction of female rat aorta by enhancing cyclooxygenase-2 and thromboxane function. Am J Physiol Heart Circ Physiol (2005) 0.86
Cardiovascular alteration and treatment of hypertension: do men and women differ? Endocrine (2005) 0.86
Arteriolar responses to vasodilator stimuli and elevated P(O2) in renin congenic and Dahl salt-sensitive rats. Microcirculation (2004) 0.86
A coupled-oscillator model of ovarian-cycle synchrony among female rats. J Theor Biol (1992) 0.85
Microvascular structure and function in salt-sensitive hypertension. Microcirculation (2002) 0.85
Cardiovascular disease in women: sex differences in presentation, risk factors, and evaluation. Curr Cardiol Rep (2005) 0.85
Gender differences in correlations among cardiovascular risk factors. Gend Med (2006) 0.85
Endothelial dysfunction: implications for therapy of cardiovascular diseases. Ann Pharmacother (1998) 0.85
Renal hemodynamic and tubular responses to salt in women using oral contraceptives. Kidney Int (2003) 0.84
Differential effect of cytochrome P-450 omega-hydroxylase inhibition on O2-induced constriction of arterioles in SHR with early and established hypertension. Microcirculation (2001) 0.83
Genotype-by-sex interaction on fasting insulin concentration: the HyperGEN study. Diabetes (2007) 0.83
Gender differences in vascular smooth muscle reactivity to increases in extracellular sodium salt. Hypertension (2002) 0.83
Effects of salt intake and angiotensin II on vascular reactivity to endothelin-1. J Pharmacol Exp Ther (2001) 0.82
Effect of estradiol-drospirenone hormone treatment on myocardial perfusion reserve in postmenopausal women with angina pectoris. Am J Cardiol (2007) 0.82
Effects of high sodium intake diet on the vascular reactivity to phenylephrine on rat isolated caudal and renal vascular beds: Endothelial modulation. Life Sci (2005) 0.82
Neural and local control of arterioles in SHR. Hypertension (1984) 0.82
Gender difference in vascular and platelet reactivity to thromboxane A(2)-mimetic U46619 and to endothelial dependent vasodilation in Zucker fatty (hypertensive, hyperinsulinemic) diabetic rats. Diabetes Res Clin Pract (2003) 0.82
High dietary salt reduces the contribution of 20-HETE to arteriolar oxygen responsiveness in skeletal muscle. Am J Physiol Heart Circ Physiol (2006) 0.81
Gender differences in vascular reactivity of aortas from rats with and without portal hypertension. J Gastroenterol Hepatol (2005) 0.81
Differences in risk factors for acute coronary syndromes between men and women. Acta Cardiol (2007) 0.81
Non-genomic vascular actions of female sex hormones: physiological implications and signalling pathways. Clin Exp Pharmacol Physiol (2007) 0.80
Androgens drive divergent responses to salt stress in male versus female rat kidneys. Genomics (2007) 0.80
Gender difference in the role of endothelium-derived relaxing factors modulating renal vascular reactivity. Eur J Pharmacol (2004) 0.78
Muscle arteriolar and venular reactivity in two models of hypertensive rats. Microvasc Res (2005) 0.77
Gender differences in vascular disease: not a simple explanation. J Hypertens (2007) 0.77
Contribution of extrinsic factors and intrinsic vascular alterations to reduced arteriolar reactivity with high-salt diet and hypertension. Microcirculation (2000) 0.77
Tamoxifen and estrogen attenuate enhanced vascular reactivity induced by estrogen deficiency in rat carotid arteries. Biochem Pharmacol (2006) 0.76
The rat genome database curators: who, what, where, why. PLoS Comput Biol (2009) 2.86
The Rat Genome Database 2013--data, tools and users. Brief Bioinform (2013) 1.94
Three ontologies to define phenotype measurement data. Front Genet (2012) 1.74
AT1 receptors prevent salt-induced vascular dysfunction in isolated middle cerebral arteries of 2 kidney-1 clip hypertensive rats. Am J Hypertens (2013) 1.65
Ontology searching and browsing at the Rat Genome Database. Database (Oxford) (2012) 1.51
The Rat Genome Database pathway portal. Database (Oxford) (2011) 1.40
Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol (2008) 1.37
Chronic intermittent hypoxia impairs endothelium-dependent dilation in rat cerebral and skeletal muscle resistance arteries. Am J Physiol Heart Circ Physiol (2003) 1.37
Effect of high-salt diet on vascular relaxation and oxidative stress in mesenteric resistance arteries. J Vasc Res (2007) 1.36
Gene targeting in the rat: advances and opportunities. Trends Genet (2010) 1.25
Identifying multiple causative genes at a single GWAS locus. Genome Res (2013) 1.25
Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. Am J Physiol Renal Physiol (2007) 1.24
PhenoMiner: quantitative phenotype curation at the rat genome database. Database (Oxford) (2013) 1.24
The Rat Genome Database curation tool suite: a set of optimized software tools enabling efficient acquisition, organization, and presentation of biological data. Database (Oxford) (2011) 1.21
Exploring genetic, genomic, and phenotypic data at the rat genome database. Curr Protoc Bioinformatics (2012) 1.20
Effect of high-salt diet on NO release and superoxide production in rat aorta. Am J Physiol Heart Circ Physiol (2003) 1.13
Chronic intermittent hypoxia alters NE reactivity and mechanics of skeletal muscle resistance arteries. J Appl Physiol (1985) (2005) 1.12
Role of superoxide and angiotensin II suppression in salt-induced changes in endothelial Ca2+ signaling and NO production in rat aorta. Am J Physiol Heart Circ Physiol (2006) 1.10
Reduced angiotensin II and oxidative stress contribute to impaired vasodilation in Dahl salt-sensitive rats on low-salt diet. Hypertension (2005) 1.10
BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. Physiol Genomics (2006) 1.09
Time-course and mechanisms of restored vascular relaxation by reduced salt intake and angiotensin II infusion in rats fed a high-salt diet. Microcirculation (2009) 1.07
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries. Am J Physiol Heart Circ Physiol (2010) 1.06
Introgression of chromosome 13 in Dahl salt-sensitive genetic background restores cerebral vascular relaxation. Am J Physiol Heart Circ Physiol (2004) 1.06
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. J Am Soc Nephrol (2013) 1.04
Ventilatory phenotypes among four strains of adult rats. J Appl Physiol (1985) (2002) 1.02
Acute and chronic angiotensin-(1-7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats. Am J Physiol Heart Circ Physiol (2011) 1.01
Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2. Am J Physiol Heart Circ Physiol (2009) 0.98
Integration of hypoxic dilation signaling pathways for skeletal muscle resistance arteries. Am J Physiol Regul Integr Comp Physiol (2002) 0.97
The pathway ontology - updates and applications. J Biomed Semantics (2014) 0.96
Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. Am J Physiol Heart Circ Physiol (2010) 0.96
Rat Genome Database: a unique resource for rat, human, and mouse quantitative trait locus data. Physiol Genomics (2013) 0.96
The clinical measurement, measurement method and experimental condition ontologies: expansion, improvements and new applications. J Biomed Semantics (2013) 0.96
Restoration of normal vascular relaxation mechanisms in cerebral arteries by chromosomal substitution in consomic SS.13BN rats. Am J Physiol Heart Circ Physiol (2005) 0.95
Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. Hypertension (2012) 0.95
Introgression of the Brown Norway renin allele onto the Dahl salt-sensitive genetic background increases Cu/Zn SOD expression in cerebral arteries. Am J Hypertens (2011) 0.93
Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. Physiol Genomics (2006) 0.93
High-salt diet depresses acetylcholine reactivity proximal to NOS activation in cerebral arteries. Am J Physiol Heart Circ Physiol (2002) 0.92
Effects of high-salt diet on CYP450-4A omega-hydroxylase expression and active tone in mesenteric resistance arteries. Am J Physiol Heart Circ Physiol (2004) 0.92
The updated RGD Pathway Portal utilizes increased curation efficiency and provides expanded pathway information. Hum Genomics (2013) 0.90
Skeletal muscle arteriolar reactivity in SS.BN13 consomic rats and Dahl salt-sensitive rats. Hypertension (2003) 0.89
Chronic At1 receptor blockade alters the mechanisms mediating hypoxic dilation in middle cerebral arteries. J Cardiovasc Pharmacol (2005) 0.88
Depression, psychological stress, vascular dysfunction, and cardiovascular disease: thinking outside the barrel. J Appl Physiol (1985) (2010) 0.86
Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat. Clin Sci (Lond) (2013) 0.86
Modulation of vascular O2 responses by cytochrome 450-4A omega-hydroxylase metabolites in Dahl salt-sensitive rats. Microcirculation (2009) 0.86
Does 20-hydroxyeicosatetraenoic acid contribute to sex differences in cardiovascular risk by increasing oxidative stress? Hypertension (2007) 0.86
Arteriolar responses to vasodilator stimuli and elevated P(O2) in renin congenic and Dahl salt-sensitive rats. Microcirculation (2004) 0.86
Rat Strain Ontology: structured controlled vocabulary designed to facilitate access to strain data at RGD. J Biomed Semantics (2013) 0.85
Disease pathways at the Rat Genome Database Pathway Portal: genes in context-a network approach to understanding the molecular mechanisms of disease. Hum Genomics (2014) 0.84
Modulation by cytochrome P450-4A ω-hydroxylase enzymes of adrenergic vasoconstriction and response to reduced PO₂ in mesenteric resistance arteries of Dahl salt-sensitive rats. Microcirculation (2010) 0.84
Expression of cytochrome P450-4A isoforms in the rat cremaster muscle microcirculation. Microcirculation (2004) 0.84
Low-dose angiotensin II infusion restores vascular function in cerebral arteries of high salt-fed rats by increasing copper/zinc superoxide dimutase expression. Am J Hypertens (2013) 0.84
Reduced angiotensin II levels cause generalized vascular dysfunction via oxidant stress in hamster cheek pouch arterioles. Microvasc Res (2013) 0.83
Restoration of cerebral vascular relaxation in renin congenic rats by introgression of the Dahl R renin gene. Am J Hypertens (2009) 0.82
Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats. Clin Sci (Lond) (2013) 0.82
Analysis of disease-associated objects at the Rat Genome Database. Database (Oxford) (2013) 0.81
Chronic AT(1) receptor blockade alters mechanisms mediating responses to hypoxia in rat skeletal muscle resistance arteries. Am J Physiol Heart Circ Physiol (2004) 0.81
Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats. Kidney Int (2012) 0.80
Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin. Am J Physiol Heart Circ Physiol (2004) 0.78
Parenchymal tissue cytochrome P450 4A enzymes contribute to oxygen-induced alterations in skeletal muscle arteriolar tone. Microvasc Res (2002) 0.78
Effects of AT1 receptor blockade on plasma thromboxane A2 (TXA2) level and skin microcirculation in young healthy women on low salt diet. Kidney Blood Press Res (2013) 0.78
Comparison of 2 rat breeding schemes using conventional caging. J Am Assoc Lab Anim Sci (2013) 0.78
A novel mechanism for regulation of retinal blood flow by lactate: gap junctions, hypoxia, and pericytes. Am J Physiol Heart Circ Physiol (2006) 0.77
Microcirculation in a mouse model of Duchenne muscular dystrophy: another blow to the vascular hypothesis? J Appl Physiol (1985) (2011) 0.76
CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension. Microvasc Res (2009) 0.76
Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. Physiol Genomics (2010) 0.76
Enhancement of resting-state fcMRI networks by prior sensory stimulation. Brain Connect (2014) 0.75
Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. Am J Physiol Heart Circ Physiol (2013) 0.75
Response to "Does angiotensin-dependent superoxide production help to prevent salt-induced endothelial dysfunction in 2 kidney-1 clip hypertensive rats?". Am J Hypertens (2014) 0.75
Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats. J Vasc Res (2016) 0.75
Interaction of myogenic mechanisms and hypoxic dilation in rat middle cerebral arteries. Am J Physiol Heart Circ Physiol (2002) 0.75
Physiological genomics: from bench to bedside. Exp Physiol (2007) 0.75