Published in J Neurosci on May 01, 1991
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture. Proc Natl Acad Sci U S A (2001) 3.17
Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J Neurosci (2009) 2.35
Connexin and pannexin mediated cell-cell communication. Neuron Glia Biol (2007) 1.86
Intercellular calcium signaling via gap junctions in glioma cells. J Cell Biol (1992) 1.80
Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics (2010) 1.60
Intercellular communication in spinal cord astrocytes: fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation. J Neurosci (2000) 1.56
Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Res Brain Res Rev (2004) 1.54
Formation of heteromeric gap junction channels by connexins 40 and 43 in vascular smooth muscle cells. Proc Natl Acad Sci U S A (1999) 1.53
Connexin35 mediates electrical transmission at mixed synapses on Mauthner cells. J Neurosci (2003) 1.50
Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells. J Physiol (1999) 1.46
Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration. Antioxid Redox Signal (2009) 1.34
Gap junction hemichannels in astrocytes of the CNS. Acta Physiol Scand (2003) 1.31
Array analysis of gene expression in connexin-43 null astrocytes. Physiol Genomics (2003) 1.24
Properties of gap junction channels formed by Cx46 alone and in combination with Cx50. Biophys J (2000) 1.24
IL-1beta differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels. Proc Natl Acad Sci U S A (1999) 1.23
Spinal astrocyte gap junctions contribute to oxaliplatin-induced mechanical hypersensitivity. J Pain (2013) 1.16
Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity. J Neurosci (2011) 1.15
The role of gap junction channels during physiologic and pathologic conditions of the human central nervous system. J Neuroimmune Pharmacol (2012) 1.13
Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice. Gastroenterology (2013) 1.12
Calcium waves between astrocytes from Cx43 knockout mice. Glia (1998) 1.11
Calmodulin kinase pathway mediates the K+-induced increase in Gap junctional communication between mouse spinal cord astrocytes. J Neurosci (2001) 1.06
Gap-junctional coupling between neurons and astrocytes in primary central nervous system cultures. Proc Natl Acad Sci U S A (1999) 1.04
FGF-receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9. Development (2010) 1.03
Gap junction dysfunction in the prefrontal cortex induces depressive-like behaviors in rats. Neuropsychopharmacology (2011) 1.02
Connexin32 gap junction channels in stably transfected cells: unitary conductance. Biophys J (1991) 1.02
Gap junction intercellular communication mediated by connexin43 in astrocytes is essential for their resistance to oxidative stress. J Biol Chem (2013) 0.99
Modulation of astrocyte P2Y1 receptors by the carboxyl terminal domain of the gap junction protein Cx43. Glia (2008) 0.93
Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo. Glia (2008) 0.93
Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases. Front Cell Neurosci (2014) 0.91
Electrophysiological properties and gap junction coupling of striatal astrocytes. Neurochem Int (2008) 0.88
Astrocytes and neurosteroids: metabolism of pregnenolone and dehydroepiandrosterone. Regulation by cell density. J Cell Biol (1993) 0.88
Electrical coupling between glial cells in the rat retina. Glia (2001) 0.88
A stochastic two-dimensional model of intercellular Ca2+ wave spread in glia. Biophys J (2005) 0.86
Depression of intraocular pressure following inactivation of connexin43 in the nonpigmented epithelium of the ciliary body. Invest Ophthalmol Vis Sci (2009) 0.85
Lipopolysaccharide induces degradation of connexin43 in rat astrocytes via the ubiquitin-proteasome proteolytic pathway. PLoS One (2013) 0.85
Extracellular K⁺ and astrocyte signaling via connexin and pannexin channels. Neurochem Res (2012) 0.84
Profiling of astrocyte properties in the hyperammonaemic brain: shedding new light on the pathophysiology of the brain damage in hyperammonaemia. J Inherit Metab Dis (2008) 0.82
Anti-inflammatory effects of the anticonvulsant drug levetiracetam on electrophysiological properties of astroglia are mediated via TGFβ1 regulation. Br J Pharmacol (2011) 0.82
Ontogeny of connexin 32 and 43 expression in the cerebral cortices of ovine fetuses, newborns, and adults. Brain Res (2008) 0.81
Internal ribosomal entry site (IRES) activity generates endogenous carboxyl-terminal domains of Cx43 and is responsive to hypoxic conditions. J Biol Chem (2014) 0.81
Increased intercellular communication in mouse astrocytes exposed to hyposmotic shocks. Glia (1998) 0.80
Influence of drugs on gap junctions in glioma cell lines and primary astrocytes in vitro. Front Physiol (2014) 0.80
Connexin36 gap junction blockade is ineffective at reducing seizure-like event activity in neocortical mouse slices. Epilepsy Res Treat (2011) 0.79
Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology? Front Aging Neurosci (2014) 0.78
Connexins and their channels in inflammation. Crit Rev Biochem Mol Biol (2016) 0.77
Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition. Biochim Biophys Acta (2015) 0.77
Antidepressants Impact Connexin 43 Channel Functions in Astrocytes. Front Cell Neurosci (2016) 0.76
Dexamethasone and levetiracetam reduce hetero-cellular gap-junctional coupling between F98 glioma cells and glial cells in vitro. J Neurooncol (2016) 0.75
Vasodilation by in vivo activation of astrocyte endfeet via two-photon calcium uncaging as a strategy to prevent brain ischemia. J Biomed Opt (2013) 0.75
Role of Astroglial Hemichannels and Pannexons in Memory and Neurodegenerative Diseases. Front Integr Neurosci (2016) 0.75
Evaluation of Connexin 43 Redistribution and Endocytosis in Astrocytes Subjected to Ischemia/Reperfusion or Oxygen-Glucose Deprivation and Reoxygenation. Biomed Res Int (2017) 0.75
Maternal treatment with glucocorticoids modulates gap junction protein expression in the ovine fetal brain. Neuroscience (2014) 0.75
An electrically resistive sheet of glial cells for amplifying signals of neuronal extracellular recordings. Appl Phys Lett (2016) 0.75
Estradiol Receptors Regulate Differential Connexin 43 Expression in F98 and C6 Glioma Cell Lines. PLoS One (2016) 0.75
The "syncytial tissue triad": a model for understanding how gap junctions participate in the local control of penile erection. World J Urol (1997) 0.75
Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation. Sci Rep (2016) 0.75
Connexin Hemichannels in Astrocytes: An Assessment of Controversies Regarding Their Functional Characteristics. Neurochem Res (2017) 0.75
Connexin-Dependent Neuroglial Networking as a New Therapeutic Target. Front Cell Neurosci (2017) 0.75
Gap junctions: new tools, new answers, new questions. Neuron (1991) 4.93
Equilibrium properties of a voltage-dependent junctional conductance. J Gen Physiol (1981) 3.91
Neutralization of primary human immunodeficiency virus type 1 isolates by the broadly reactive anti-V3 monoclonal antibody, 447-52D. J Virol (1994) 3.33
Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody. Proc Natl Acad Sci U S A (1994) 3.33
Kinetic properties of a voltage-dependent junctional conductance. J Gen Physiol (1981) 3.33
Gap junctional conductance is a simple and sensitive function of intracellular pH. Science (1981) 2.64
Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions. Proc Natl Acad Sci U S A (1989) 2.53
Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron (1996) 2.52
P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol (2008) 2.49
A human monoclonal antibody to a complex epitope in the V3 region of gp120 of human immunodeficiency virus type 1 has broad reactivity within and outside clade B. J Virol (1995) 2.35
Physiology and pharmacology of gap junctions. Annu Rev Physiol (1985) 2.34
Differential expression of three gap junction proteins in developing and mature brain tissues. Proc Natl Acad Sci U S A (1989) 2.34
cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide. Proc Natl Acad Sci U S A (1986) 2.20
Gap junction channels: distinct voltage-sensitive and -insensitive conductance states. Biophys J (1994) 1.99
Gap junctions in the brain: where, what type, how many and why? Trends Neurosci (1993) 1.97
Functional analysis of human cardiac gap junction channel mutants. Proc Natl Acad Sci U S A (1991) 1.94
Recombinant human nerve growth factor in the treatment of diabetic polyneuropathy. NGF Study Group. Neurology (1998) 1.92
Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation. Circ Res (1994) 1.92
Volatile anesthetics block intercellular communication between neonatal rat myocardial cells. Circ Res (1989) 1.90
Voltage dependence of junctional conductance in early amphibian embryos. Science (1979) 1.90
Functional properties of channels formed by the neuronal gap junction protein connexin36. J Neurosci (1999) 1.90
Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity. J Immunol (1997) 1.89
Some electrical and pharmacological properties of gap junctions between adult ventricular myocytes. Am J Physiol (1985) 1.88
Wnt-1 regulation of connexin43 in cardiac myocytes. J Clin Invest (2000) 1.87
Molecular characterization and functional expression of the human cardiac gap junction channel. J Cell Biol (1990) 1.81
Bone morphogenetic proteins induce astroglial differentiation of oligodendroglial-astroglial progenitor cells. J Neurosci (1997) 1.77
Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells. Biophys J (1991) 1.71
Gating of gap junction channels. Biophys J (1984) 1.70
Single-channel events and gating behavior of the cardiac gap junction channel. Proc Natl Acad Sci U S A (1988) 1.70
Quinine blocks specific gap junction channel subtypes. Proc Natl Acad Sci U S A (2001) 1.67
Bone morphogenetic proteins in the nervous system. Trends Neurosci (1997) 1.62
Connexin43 null mice reveal that astrocytes express multiple connexins. Brain Res Brain Res Rev (2000) 1.61
How to close a gap junction channel. Efficacies and potencies of uncoupling agents. Methods Mol Biol (2001) 1.61
Isolated liver gap junctions: gating of transjunctional currents is similar to that in intact pairs of rat hepatocytes. Proc Natl Acad Sci U S A (1986) 1.57
Reduction of gap junctional conductance by microinjection of antibodies against the 27-kDa liver gap junction polypeptide. Proc Natl Acad Sci U S A (1985) 1.56
Intercellular communication in spinal cord astrocytes: fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation. J Neurosci (2000) 1.56
Activation of a voltage-insensitive conductance by inward calcium current. Nature (1975) 1.53
Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineage fate. Dev Neurosci (2000) 1.51
Gap junctional conductance: comparison of sensitivities to H and Ca ions. Proc Natl Acad Sci U S A (1982) 1.47
Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype. J Neurosci (1999) 1.46
Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells. J Physiol (1999) 1.46
Phosphorylation shifts unitary conductance and modifies voltage dependent kinetics of human connexin43 gap junction channels. Biophys J (1992) 1.41
Gap junctions in vascular tissues. Evaluating the role of intercellular communication in the modulation of vasomotor tone. Circ Res (1996) 1.40
Permeability of gap junctions between embryonic cells of Fundulus: a reevaluation. Dev Biol (1978) 1.37
Electrophysiological properties of gap junctions between dissociated pairs of rat hepatocytes. J Cell Biol (1986) 1.37
Reciprocal regulation of the junctional proteins claudin-1 and connexin43 by interleukin-1beta in primary human fetal astrocytes. J Neurosci (2000) 1.33
A vaccine-elicited, single viral epitope-specific cytotoxic T lymphocyte response does not protect against intravenous, cell-free simian immunodeficiency virus challenge. J Virol (1995) 1.33
Emerging peptide nanomedicine to regenerate tissues and organs. J Intern Med (2010) 1.32
Gap junction-mediated intercellular diffusion of Ca2+ in cultured human corporal smooth muscle cells. Am J Physiol (1992) 1.31
Phosphorylation of connexin43 and the regulation of neonatal rat cardiac myocyte gap junctions. J Mol Cell Cardiol (1997) 1.30
Gap junctional conductance and permeability are linearly related. Science (1986) 1.29
Involvement of gap junctions in tumorigenesis: transfection of tumor cells with connexin 32 cDNA retards growth in vivo. Proc Natl Acad Sci U S A (1991) 1.29
Expression of gap junction channels in communication-incompetent cells after stable transfection with cDNA encoding connexin 32. Proc Natl Acad Sci U S A (1990) 1.28
Gating characteristics of a steeply voltage-dependent gap junction channel in rat Schwann cells. J Gen Physiol (1993) 1.25
Evidence for secretory pathway localization of a voltage-dependent anion channel isoform. Proc Natl Acad Sci U S A (2000) 1.25
Properties of gap junction channels formed by Cx46 alone and in combination with Cx50. Biophys J (2000) 1.24
Proteoglycans and glycosaminoglycans induce gap junction synthesis and function in primary liver cultures. J Cell Biol (1987) 1.24
IL-1beta differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels. Proc Natl Acad Sci U S A (1999) 1.23
Properties of gap junction channels formed of connexin 45 endogenously expressed in human hepatoma (SKHep1) cells. Am J Physiol (1995) 1.22
The role of aquaporin-4 in the blood-brain barrier development and integrity: studies in animal and cell culture models. Neuroscience (2004) 1.21
Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia. Proc Natl Acad Sci U S A (1992) 1.21
Development of bone morphogenetic protein receptors in the nervous system and possible roles in regulating trkC expression. J Neurosci (1998) 1.19
Nerve growth factor regulates the expression of brain-derived neurotrophic factor mRNA in the peripheral nervous system. Mol Cell Neurosci (1996) 1.18
Cytokine regulation of neuronal differentiation of hippocampal progenitor cells. Nature (1993) 1.18
Phosphorylation of connexin 32, a hepatocyte gap-junction protein, by cAMP-dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II. Eur J Biochem (1990) 1.16
Gap junction distribution is altered between cardiac myocytes infected with Trypanosoma cruzi. Circ Res (1992) 1.16
Inotropic agents modulate gap junctional conductance between cardiac myocytes. Am J Physiol (1988) 1.16
Inhibition of endothelial cell migration, intercellular communication, and vascular tube formation by thromboxane A(2). J Biol Chem (1999) 1.15
Nerve growth factor administration protects against experimental diabetic sensory neuropathy. Brain Res (1994) 1.14
Oligodendrocytes express gap junction proteins connexin32 and connexin45. Glia (1997) 1.12
Influence of cytosolic pH on receptor-mediated endocytosis of asialoorosomucoid. Am J Physiol (1988) 1.12
CSF-1 deficiency in mice results in abnormal brain development. Development (1996) 1.11
Effect of calcium on the dissociation of the mature rat heart into individual and paired myocytes: electrical properties of cell pairs. Circ Res (1986) 1.11
Calcium waves between astrocytes from Cx43 knockout mice. Glia (1998) 1.11
Nerve growth factor prevents experimental cisplatin neuropathy. Ann Neurol (1992) 1.11
KATP channels regulate mitogenically induced proliferation in primary rat hepatocytes and human liver cell lines. Implications for liver growth control and potential therapeutic targeting. J Biol Chem (2000) 1.09
Regulation of gap junctional conductance. Am J Physiol (1985) 1.09
Gap junctions remain open during cytochrome c-induced cell death: relationship of conductance to 'bystander' cell killing. Cell Death Differ (2006) 1.08
Connexin32 gap junction channels in stably transfected cells. Equilibrium and kinetic properties. Biophys J (1991) 1.08
Gap junctions. Multiplicity of controls in differentiated and undifferentiated cells and possible functional implications. Adv Second Messenger Phosphoprotein Res (1993) 1.08
Activities of (-)-carbovir and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro. Antimicrob Agents Chemother (1990) 1.08
Control of intercellular communication by voltage dependence of gap junctional conductance. J Neurosci (1983) 1.08
Nerve growth factor prevents toxic neuropathy in mice. Ann Neurol (1991) 1.07
Substance P and somatostatin regulate sympathetic noradrenergic function. Science (1983) 1.07
Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia. J Neurosci Res (2000) 1.07
Gap junctions in the nervous system. Brain Res Brain Res Rev (2000) 1.07
Calmodulin kinase pathway mediates the K+-induced increase in Gap junctional communication between mouse spinal cord astrocytes. J Neurosci (2001) 1.06
Human immunodeficiency virus infection and syncytium formation in HeLa cells expressing glycophospholipid-anchored CD4. J Virol (1991) 1.06
Determination of synaptic phenotype: insulin and cAMP independently initiate development of electrotonic coupling between cultured sympathetic neurons. Proc Natl Acad Sci U S A (1984) 1.06
The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia. Invest Ophthalmol Vis Sci (1998) 1.06
Transforming growth factor alpha, but not epidermal growth factor, promotes the survival of sensory neurons in vitro. J Neurosci (1992) 1.06
Cutaneous temperature receptors. Annu Rev Physiol (1986) 1.06