Published in Mol Microbiol on June 04, 2008
Bacterial persistence by RNA endonucleases. Proc Natl Acad Sci U S A (2011) 3.52
The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell (2009) 2.01
Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol Microbiol (2009) 1.76
Escherichia coli toxin/antitoxin pair MqsR/MqsA regulate toxin CspD. Environ Microbiol (2010) 1.46
To be or not to be: regulation of restriction-modification systems and other toxin-antitoxin systems. Nucleic Acids Res (2013) 1.42
Toxin-antitoxin systems as multilevel interaction systems. Toxins (Basel) (2014) 1.36
RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB. J Mol Biol (2009) 1.35
Bacterial persister cell formation and dormancy. Appl Environ Microbiol (2013) 1.28
Toxin-antitoxin systems: Biology, identification, and application. Mob Genet Elements (2013) 1.25
Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules. PLoS One (2010) 1.22
Translational regulation of gene expression by an anaerobically induced small non-coding RNA in Escherichia coli. J Biol Chem (2010) 1.19
Three Mycobacterium tuberculosis Rel toxin-antitoxin modules inhibit mycobacterial growth and are expressed in infected human macrophages. J Bacteriol (2008) 1.17
The bacterial translation stress response. FEMS Microbiol Rev (2014) 1.14
Comparative metagenomic analysis of plasmid encoded functions in the human gut microbiome. BMC Genomics (2010) 1.11
Conditional cooperativity in toxin-antitoxin regulation prevents random toxin activation and promotes fast translational recovery. Nucleic Acids Res (2012) 1.06
Regulation of enteric vapBC transcription: induction by VapC toxin dimer-breaking. Nucleic Acids Res (2012) 1.06
The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site. Protein Sci (2012) 1.05
The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity. Structure (2012) 1.00
Regulating toxin-antitoxin expression: controlled detonation of intracellular molecular timebombs. Toxins (Basel) (2014) 1.00
The human gut mobile metagenome: a metazoan perspective. Gut Microbes (2011) 0.99
A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism. Nucleic Acids Res (2014) 0.97
Transcriptional cross-activation between toxin-antitoxin systems of Escherichia coli. BMC Microbiol (2013) 0.96
Characterization of Escherichia coli dinJ-yafQ toxin-antitoxin system using insights from mutagenesis data. J Bacteriol (2012) 0.96
MazF-induced growth inhibition and persister generation in Escherichia coli. J Biol Chem (2013) 0.94
Toxin-antitoxin genes of the Gram-positive pathogen Streptococcus pneumoniae: so few and yet so many. Microbiol Mol Biol Rev (2012) 0.94
The three vibrio cholerae chromosome II-encoded ParE toxins degrade chromosome I following loss of chromosome II. J Bacteriol (2010) 0.93
RelE-mediated dormancy is enhanced at high cell density in Escherichia coli. J Bacteriol (2011) 0.91
The Escherichia coli toxin MqsR destabilizes the transcriptional repression complex formed between the antitoxin MqsA and the mqsRA operon promoter. J Biol Chem (2012) 0.89
Structure of the Proteus vulgaris HigB-(HigA)2-HigB toxin-antitoxin complex. J Biol Chem (2013) 0.87
Keeping the Wolves at Bay: Antitoxins of Prokaryotic Type II Toxin-Antitoxin Systems. Front Mol Biosci (2016) 0.85
A general model for toxin-antitoxin module dynamics can explain persister cell formation in E. coli. PLoS Comput Biol (2013) 0.84
Mechanisms of toxin inhibition and transcriptional repression by Escherichia coli DinJ-YafQ. J Biol Chem (2014) 0.83
Functional and structural analysis of HicA3-HicB3, a novel toxin-antitoxin system of Yersinia pestis. J Bacteriol (2014) 0.82
A moderate toxin, GraT, modulates growth rate and stress tolerance of Pseudomonas putida. J Bacteriol (2013) 0.81
The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res (2014) 0.81
What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence? Front Microbiol (2016) 0.81
Conditional cooperativity of toxin - antitoxin regulation can mediate bistability between growth and dormancy. PLoS Comput Biol (2013) 0.81
Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding. Nucleic Acids Res (2015) 0.81
Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics. Nucleic Acids Res (2014) 0.80
Hypothesis: type I toxin-antitoxin genes enter the persistence field-a feedback mechanism explaining membrane homoeostasis. Philos Trans R Soc Lond B Biol Sci (2016) 0.80
Structure, Biology, and Therapeutic Application of Toxin-Antitoxin Systems in Pathogenic Bacteria. Toxins (Basel) (2016) 0.78
The intrinsically disordered domain of the antitoxin Phd chaperones the toxin Doc against irreversible inactivation and misfolding. J Biol Chem (2014) 0.78
Unrelated toxin-antitoxin systems cooperate to induce persistence. J R Soc Interface (2015) 0.78
Toxins of Prokaryotic Toxin-Antitoxin Systems with Sequence-Specific Endoribonuclease Activity. Toxins (Basel) (2017) 0.78
Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Res (2017) 0.77
The axe-txe complex of Enterococcus faecium presents a multilayered mode of toxin-antitoxin gene expression regulation. PLoS One (2013) 0.77
Wake me when it's over - Bacterial toxin-antitoxin proteins and induced dormancy. Exp Biol Med (Maywood) (2016) 0.76
mRNA bound to the 30S subunit is a HigB toxin substrate. RNA (2016) 0.76
An intrinsically disordered entropic switch determines allostery in Phd-Doc regulation. Nat Chem Biol (2016) 0.76
Persistent bacterial infections and persister cells. Nat Rev Microbiol (2017) 0.75
Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon. Nucleic Acids Res (2017) 0.75
Crystallization of two operator complexes from the Vibrio cholerae HigBA2 toxin-antitoxin module. Acta Crystallogr F Struct Biol Commun (2015) 0.75
Key players in the genetic switch of bacteriophage TP901-1. Biophys J (2011) 0.75
Stabilization of the Virulence Plasmid pSLT of Salmonella Typhimurium by Three Maintenance Systems and Its Evaluation by Using a New Stability Test. Front Mol Biosci (2016) 0.75
Mechanisms for Differential Protein Production in Toxin-Antitoxin Systems. Toxins (Basel) (2017) 0.75
AtaT blocks translation initiation by N-acetylation of the initiator tRNA(fMet). Nat Chem Biol (2017) 0.75
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res (2005) 6.61
The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell (2003) 6.01
Dysfunctional MreB inhibits chromosome segregation in Escherichia coli. EMBO J (2003) 4.37
The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex. Mol Microbiol (2005) 4.15
Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA. J Mol Biol (2003) 3.76
Bacterial persistence by RNA endonucleases. Proc Natl Acad Sci U S A (2011) 3.52
Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol Microbiol (2002) 3.44
RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA. Mol Microbiol (2003) 3.32
(p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity. Cell (2013) 3.28
F-actin-like filaments formed by plasmid segregation protein ParM. EMBO J (2002) 2.91
Prokaryotic DNA segregation by an actin-like filament. EMBO J (2002) 2.78
Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon. Genes Dev (2002) 2.75
Plasmid segregation mechanisms. Annu Rev Genet (2005) 2.69
Bacterial mitosis: ParM of plasmid R1 moves plasmid DNA by an actin-like insertional polymerization mechanism. Mol Cell (2003) 2.60
Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system. Mol Microbiol (2004) 2.29
HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea. J Bacteriol (2008) 2.26
Movement and equipositioning of plasmids by ParA filament disassembly. Proc Natl Acad Sci U S A (2009) 2.21
The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell (2009) 2.01
Two higBA loci in the Vibrio cholerae superintegron encode mRNA cleaving enzymes and can stabilize plasmids. Mol Microbiol (2006) 2.00
Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli. Genes Dev (2006) 1.93
Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA. Proc Natl Acad Sci U S A (2011) 1.92
Bacterial mitosis: partitioning protein ParA oscillates in spiral-shaped structures and positions plasmids at mid-cell. Mol Microbiol (2004) 1.88
Regular cellular distribution of plasmids by oscillating and filament-forming ParA ATPase of plasmid pB171. Mol Microbiol (2006) 1.82
Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol Microbiol (2009) 1.76
A problem of persistence: still more questions than answers? Nat Rev Microbiol (2013) 1.68
Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation. J Biol Chem (2008) 1.62
Molecular mechanism of bacterial persistence by HipA. Mol Cell (2013) 1.48
Novel coiled-coil cell division factor ZapB stimulates Z ring assembly and cell division. Mol Microbiol (2008) 1.41
Structural analysis of the ParR/parC plasmid partition complex. EMBO J (2007) 1.40
RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB. J Mol Biol (2009) 1.35
Spatial resolution of two bacterial cell division proteins: ZapA recruits ZapB to the inner face of the Z-ring. Mol Microbiol (2010) 1.32
Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose. Plant J (2006) 1.28
Delayed-relaxed response explained by hyperactivation of RelE. Mol Microbiol (2004) 1.25
Translation affects YoeB and MazF messenger RNA interferase activities by different mechanisms. Nucleic Acids Res (2008) 1.23
Ectopic production of VapCs from Enterobacteria inhibits translation and trans-activates YoeB mRNA interferase. Mol Microbiol (2009) 1.19
Direct interaction of FtsZ and MreB is required for septum synthesis and cell division in Escherichia coli. EMBO J (2013) 1.13
Convergent evolution in biosynthesis of cyanogenic defence compounds in plants and insects. Nat Commun (2011) 1.10
Conditional cooperativity in toxin-antitoxin regulation prevents random toxin activation and promotes fast translational recovery. Nucleic Acids Res (2012) 1.06
Regulation of enteric vapBC transcription: induction by VapC toxin dimer-breaking. Nucleic Acids Res (2012) 1.06
ParA ATPases can move and position DNA and subcellular structures. Curr Opin Microbiol (2011) 1.05
FtsZ-ZapA-ZapB interactome of Escherichia coli. J Bacteriol (2011) 1.05
Competitive inhibition of natural antisense Sok-RNA interactions activates Hok-mediated cell killing in Escherichia coli. Nucleic Acids Res (2006) 1.04
Bacterial DNA segregation by the actin-like MreB protein. Trends Cell Biol (2005) 1.04
Structural and thermodynamic characterization of the Escherichia coli RelBE toxin-antitoxin system: indication for a functional role of differential stability. Biochemistry (2007) 1.04
The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interaction. Mol Microbiol (2006) 1.03
RNA decay by messenger RNA interferases. Methods Enzymol (2008) 1.02
Regulatory cross-talk in the double par locus of plasmid pB171. J Biol Chem (2006) 1.01
Crystal structure of the VapBC toxin-antitoxin complex from Shigella flexneri reveals a hetero-octameric DNA-binding assembly. J Mol Biol (2011) 1.01
Centromere pairing by a plasmid-encoded type I ParB protein. J Biol Chem (2007) 1.00
VapC20 of Mycobacterium tuberculosis cleaves the sarcin-ricin loop of 23S rRNA. Nat Commun (2013) 1.00
What is the mechanism of ParA-mediated DNA movement? Mol Microbiol (2010) 0.97
A mechanism for ParB-dependent waves of ParA, a protein related to DNA segregation during cell division in prokaryotes. J Mol Biol (2003) 0.95
The light-harvesting antenna of Chlorobium tepidum: interactions between the FMO protein and the major chlorosome protein CsmA studied by surface plasmon resonance. Photosynth Res (2006) 0.93
Clustering versus random segregation of plasmids lacking a partitioning function: a plasmid paradox? Plasmid (2003) 0.89
Partition-associated incompatibility caused by random assortment of pure plasmid clusters. Mol Microbiol (2005) 0.87
ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics. MBio (2014) 0.86
Prunasin hydrolases during fruit development in sweet and bitter almonds. Plant Physiol (2012) 0.85
Centromere parC of plasmid R1 is curved. Nucleic Acids Res (2004) 0.85
Single molecule activity measurements of cytochrome P450 oxidoreductase reveal the existence of two discrete functional states. ACS Chem Biol (2014) 0.85
Mammalian peptidylglycine alpha-amidating monooxygenase mRNA expression can be modulated by the La autoantigen. Mol Cell Biol (2005) 0.84
Do 14-3-3 proteins and plasma membrane H+-AtPases interact in the barley epidermis in response to the barley powdery mildew fungus? Plant Mol Biol (2002) 0.83
Protein expression, crystallization and preliminary X-ray crystallographic analysis of the isolated Shigella flexneri VapC toxin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.82
Conditional cooperativity of toxin - antitoxin regulation can mediate bistability between growth and dormancy. PLoS Comput Biol (2013) 0.81
Modulating the bacterial surface with small RNAs: a new twist on PhoP/Q-mediated lipopolysaccharide modification. Mol Microbiol (2009) 0.81
Plasmid segregation: spatial awareness at the molecular level. J Cell Biol (2007) 0.78
Crystallization of the HigBA2 toxin-antitoxin complex from Vibrio cholerae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.78
CRP-dependent positive autoregulation and proteolytic degradation regulate competence activator Sxy of Escherichia coli. Mol Microbiol (2015) 0.77
Microbiology. Dynamic instability of a bacterial engine. Science (2004) 0.75
New insights into the mucoadhesion of pectins by AFM roughness parameters in combination with SPR. Int J Pharm (2011) 0.75
Design, synthesis and evaluation of 4,7-diamino-1,10-phenanthroline G-quadruplex ligands. Bioorg Med Chem (2009) 0.75