Published in Mol Cancer on June 04, 2008
Cellular reprogramming by the conjoint action of ERα, FOXA1, and GATA3 to a ligand-inducible growth state. Mol Syst Biol (2011) 1.55
Retracted GREB1 functions as a growth promoter and is modulated by IL6/STAT3 in breast cancer. PLoS One (2012) 1.52
Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer. Breast Cancer Res (2009) 1.26
The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells. Mol Endocrinol (2009) 1.17
Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells. Am J Pathol (2010) 1.13
GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas. Hum Pathol (2013) 1.06
Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions. Am J Pathol (2009) 1.05
Gene expression profiles of estrogen receptor-positive and estrogen receptor-negative breast cancers are detectable in histologically normal breast epithelium. Clin Cancer Res (2010) 1.05
Expression of FOXO1 is associated with GATA3 and Annexin-1 and predicts disease-free survival in breast cancer. Am J Cancer Res (2011) 1.04
Human female genital tract infection by the obligate intracellular bacterium Chlamydia trachomatis elicits robust Type 2 immunity. PLoS One (2013) 1.02
Defining the genomic signature of the parous breast. BMC Med Genomics (2012) 0.97
KDM4B is a master regulator of the estrogen receptor signalling cascade. Nucleic Acids Res (2013) 0.96
Linking signaling pathways to transcriptional programs in breast cancer. Genome Res (2014) 0.95
Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet. Cancer Res (2010) 0.94
Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response. Endocr Relat Cancer (2010) 0.93
GATA3 in the urinary bladder: suppression of neoplastic transformation and down-regulation by androgens. Am J Cancer Res (2014) 0.93
Novel genes associated with lymph node metastasis in triple negative breast cancer. Sci Rep (2015) 0.92
Differential expression of breast cancer-associated genes between stage- and age-matched tumor specimens from African- and Caucasian-American Women diagnosed with breast cancer. BMC Res Notes (2012) 0.88
Biomarker profile in breast carcinomas presenting with bone metastasis. Int J Clin Exp Pathol (2009) 0.88
ER and PR signaling nodes during mammary gland development. Breast Cancer Res (2012) 0.86
Meta-analysis of the expression of the mitosis-related gene Fam83D. Oncol Lett (2012) 0.85
A minimal connected network of transcription factors regulated in human tumors and its application to the quest for universal cancer biomarkers. PLoS One (2012) 0.84
Pregnancy-induced chromatin remodeling in the breast of postmenopausal women. Int J Cancer (2012) 0.83
The ulcerative colitis marker protein WAFL interacts with accessory proteins in endocytosis. Int J Biol Sci (2010) 0.83
Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer. BMC Cancer (2014) 0.82
FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer. Oncogene (2014) 0.81
FISim: a new similarity measure between transcription factor binding sites based on the fuzzy integral. BMC Bioinformatics (2009) 0.81
Loss of GATA3 in bladder cancer promotes cell migration and invasion. Cancer Biol Ther (2014) 0.80
Cooperating transcription factors mediate the function of estrogen receptor. Chromosoma (2012) 0.79
Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges. Oncotarget (2015) 0.79
Meta-analysis of SUMO1. BMC Res Notes (2008) 0.78
Does GATA3 act in tissue-specific pathways? A meta-analysis-based approach. J Carcinog (2008) 0.78
Hormone receptor and ERBB2 status in gene expression profiles of human breast tumor samples. PLoS One (2011) 0.77
ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression. Proc Natl Acad Sci U S A (2017) 0.75
GATA3 and TRPS1 are distinct biomarkers and prognostic factors in breast cancer: database mining for GATA family members in malignancies. Oncotarget (2017) 0.75
GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis. Oncogene (2017) 0.75
A novel FOXA1/ESR1 interacting pathway: A study of Oncomine™ breast cancer microarrays. Oncol Lett (2017) 0.75
Gene expression profiling predicts clinical outcome of breast cancer. Nature (2002) 71.36
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell (2005) 14.32
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat Cell Biol (2006) 7.11
GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell (2006) 4.98
Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers. J Clin Oncol (2006) 4.84
From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response. Proc Natl Acad Sci U S A (2005) 4.16
Mutation of GATA3 in human breast tumors. Oncogene (2004) 3.92
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell (2008) 3.44
Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Res (2007) 2.95
Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma. Proc Natl Acad Sci U S A (1998) 2.80
Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis. Cancer Res (2005) 2.55
Identification of novel genes that co-cluster with estrogen receptor alpha in breast tumor biopsy specimens, using a large-scale real-time reverse transcription-PCR approach. Endocr Relat Cancer (2006) 1.96
Gene expression signature of estrogen receptor alpha status in breast cancer. BMC Genomics (2005) 1.75
GATA-3 - not just for Th2 cells anymore. Cell Mol Immunol (2007) 1.26
Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1). Breast Cancer Res (2006) 1.26
Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer. Int J Cancer (2006) 1.06
MUC1 gene overexpressed in breast cancer: structure and transcriptional activity of the MUC1 promoter and role of estrogen receptor alpha (ERalpha) in regulation of the MUC1 gene expression. Mol Cancer (2006) 1.04
Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis. BMC Genomics (2007) 1.01
A single nucleotide in an estrogen-related receptor alpha site can dictate mode of binding and peroxisome proliferator-activated receptor gamma coactivator 1alpha activation of target promoters. Mol Endocrinol (2005) 0.97
GATA3 protein as a MUC1 transcriptional regulator in breast cancer cells. Breast Cancer Res (2006) 0.96
NABC1 (BCAS1): alternative splicing and downregulation in colorectal tumors. Genomics (2000) 0.96
Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status. Cancer Epidemiol Biomarkers Prev (2007) 0.94
Characterization of the novel amplified in breast cancer-1 (NABC1) gene product. Exp Cell Res (2003) 0.92
Gata-3 and mammary cell fate. Breast Cancer Res (2007) 0.85
Cyclic regulation of T-Bet and GATA-3 in human endometrium. Reprod Sci (2008) 0.81
Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression. Genome Res (2006) 4.32
From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response. Proc Natl Acad Sci U S A (2005) 4.16
Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle. Mol Cell Biol (2004) 3.12
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metab (2007) 3.00
PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism. Mol Cell Biol (2005) 2.93
Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors. J Biol Rhythms (2005) 2.87
Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Mol Cell Biol (2003) 2.65
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metab (2007) 2.14
The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload. Cell Metab (2007) 2.11
Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis. Proc Natl Acad Sci U S A (2007) 2.03
miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway. Cell Metab (2010) 1.89
Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes Dev (2007) 1.67
Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation. J Biol Chem (2005) 1.58
Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity. Cancer Res (2009) 1.58
An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha. Mol Endocrinol (2010) 1.36
Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond. Nat Rev Cancer (2012) 1.33
The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions. Genes Dev (2010) 1.32
Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription. J Biol Chem (2005) 1.31
Lymphocyte development and function in the absence of retinoic acid-related orphan receptor alpha. J Immunol (2004) 1.28
Functional genomics identifies a mechanism for estrogen activation of the retinoic acid receptor alpha1 gene in breast cancer cells. Mol Endocrinol (2005) 1.23
Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networks. Mitochondrion (2011) 1.18
Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants. Mol Cell Biol (2002) 1.17
The NR3B subgroup: an ovERRview. Nucl Recept Signal (2007) 1.16
Loss of PGC-specific expression of the orphan nuclear receptor ERR-beta results in reduction of germ cell number in mouse embryos. Mech Dev (2004) 1.15
Nuclear receptor location analyses in mammalian genomes: from gene regulation to regulatory networks. Mol Endocrinol (2008) 1.13
Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs. PLoS Genet (2011) 1.12
Epidermal growth factor-induced signaling in breast cancer cells results in selective target gene activation by orphan nuclear receptor estrogen-related receptor alpha. Cancer Res (2005) 1.11
PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer. Cancer Res (2012) 1.10
Transcriptional control of the ERBB2 amplicon by ERRalpha and PGC-1beta promotes mammary gland tumorigenesis. Cancer Res (2010) 1.10
Estrogen-related receptor alpha (ERRalpha) is a transcriptional regulator of apolipoprotein A-IV and controls lipid handling in the intestine. J Biol Chem (2004) 1.09
β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression. Cancer Res (2013) 1.08
Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif. Mol Endocrinol (2007) 1.07
Nuclear localization of maspin is essential for its inhibition of tumor growth and metastasis. Lab Invest (2011) 1.07
Functional and physiological genomics of estrogen-related receptors (ERRs) in health and disease. Biochim Biophys Acta (2010) 1.04
Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. PLoS Genet (2011) 1.02
Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway. Mol Endocrinol (2009) 1.02
Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis. BMC Genomics (2007) 1.01
Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver. Cell Metab (2013) 0.98
Phosphatases at the heart of FoxO metabolic control. Cell Metab (2008) 0.98
A single nucleotide in an estrogen-related receptor alpha site can dictate mode of binding and peroxisome proliferator-activated receptor gamma coactivator 1alpha activation of target promoters. Mol Endocrinol (2005) 0.97
Coregulators of estrogen receptor action. Crit Rev Eukaryot Gene Expr (2002) 0.93
The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation. J Biol Chem (2003) 0.93
Ligand-independent coactivation of ERalpha AF-1 by steroid receptor RNA activator (SRA) via MAPK activation. J Steroid Biochem Mol Biol (2003) 0.92
Oligomerization of the alpha and beta isoforms of the thromboxane A2 receptor: relevance to receptor signaling and endocytosis. Cell Signal (2005) 0.91
Stromal retinoic acid receptor beta promotes mammary gland tumorigenesis. Proc Natl Acad Sci U S A (2010) 0.88
Absence of ERRalpha in female mice confers resistance to bone loss induced by age or estrogen-deficiency. PLoS One (2009) 0.87
Loss of estrogen-related receptor α promotes hepatocarcinogenesis development via metabolic and inflammatory disturbances. Proc Natl Acad Sci U S A (2013) 0.86
A frequent regulatory variant of the estrogen-related receptor alpha gene associated with BMD in French-Canadian premenopausal women. J Bone Miner Res (2005) 0.86
Estrogen related receptor-alpha enhances surfactant protein-A gene expression in fetal lung type II cells. Endocrinology (2006) 0.84
Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors. Mol Cancer Res (2013) 0.83
Estrogen-related receptor-α coordinates transcriptional programs essential for exercise tolerance and muscle fitness. Mol Endocrinol (2014) 0.81
Nuclear receptor target gene discovery using high-throughput chromatin immunoprecipitation. Methods Enzymol (2003) 0.80
Meta-analysis of SUMO1. BMC Res Notes (2008) 0.78
Cancer: Reprogramming clinical outcome. Nature (2012) 0.75
[Decoding the mode of action of the estrogen receptor through functional genomics]. Bull Cancer (2006) 0.75