Podoplanin, a novel marker of tumor-initiating cells in human squamous cell carcinoma A431.

PubWeight™: 1.33‹?› | Rank: Top 10%

🔗 View Article (PMID 18539139)

Published in Biochem Biophys Res Commun on June 06, 2008

Authors

Naho Atsumi1, Genichiro Ishii, Motohiro Kojima, Masaru Sanada, Satoshi Fujii, Atsushi Ochiai

Author Affiliations

1: Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

Articles citing this

Podoplanin associates with CD44 to promote directional cell migration. Mol Biol Cell (2010) 1.20

Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2. PLoS One (2013) 1.11

Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas. Nucl Med Biol (2010) 1.08

Impact of podoplanin expression in oral squamous cell carcinoma: clinical and histopathologic correlations. Virchows Arch (2010) 1.02

Podoplanin is regulated by AP-1 and promotes platelet aggregation and cell migration in osteosarcoma. Am J Pathol (2011) 1.02

Podoplanin expression in the development and progression of laryngeal squamous cell carcinomas. Mol Cancer (2010) 1.00

A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin. Sci Rep (2014) 0.97

Expression of Aggrus/podoplanin in bladder cancer and its role in pulmonary metastasis. Int J Cancer (2013) 0.95

Morphology and growth of mammalian cells in a liquid/liquid culture system supported with oxygenated perfluorodecalin. Biotechnol Lett (2013) 0.88

Expression of Kruppel-like factor KLF4 in mouse hair follicle stem cells contributes to cutaneous wound healing. PLoS One (2012) 0.88

Multiple drug resistance due to resistance to stem cells and stem cell treatment progress in cancer (Review). Exp Ther Med (2014) 0.88

The chimeric antibody chLpMab-7 targeting human podoplanin suppresses pulmonary metastasis via ADCC and CDC rather than via its neutralizing activity. Oncotarget (2015) 0.87

Stem cell function and stress response are controlled by protein synthesis. Nature (2016) 0.87

Podoplanin in the development and progression of oral cavity cancer: a preliminary study. Oral Implantol (Rome) (2012) 0.87

Evaluation of Podoplanin in Oral Leukoplakia and Oral Squamous Cell Carcinoma. Scientifica (Cairo) (2015) 0.85

Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation. Neuro Oncol (2012) 0.84

Podoplanin - a small glycoprotein with many faces. Am J Cancer Res (2016) 0.81

Unique intravascular tumor microenvironment predicting recurrence of lung squamous cell carcinoma. J Cancer Res Clin Oncol (2015) 0.79

The multifaceted role of podoplanin expression in hepatocellular carcinoma. Eur J Histochem (2017) 0.78

Immunophenotypic features of metastatic lymph node tumors to predict recurrence in N2 lung squamous cell carcinoma. Cancer Sci (2014) 0.78

Roles of histamine on the expression of aldehyde dehydrogenase 1 in endometrioid adenocarcinoma cell line. Cancer Med (2014) 0.77

Expressions of ABCG2, CD133, and podoplanin in salivary adenoid cystic carcinoma. Biomed Res Int (2014) 0.77

Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation. Oncotarget (2016) 0.77

Clinicopathology significance of podoplanin immunoreactivity in esophageal squamous cell carcinoma. Int J Clin Exp Pathol (2014) 0.76

Single cell time-lapse analysis reveals that podoplanin enhances cell survival and colony formation capacity of squamous cell carcinoma cells. Sci Rep (2017) 0.75

A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis. Sci Rep (2017) 0.75

Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation. Sci Rep (2017) 0.75

Role of podoplanin expression in deciding the invasive potential of ameloblastoma - A retrospective IHC study. J Oral Biol Craniofac Res (2016) 0.75

SIX1 maintains tumor basal cells via TGF-β pathway and associates with poor prognosis in esophageal cancer. Cancer Sci (2016) 0.75

SPARC is associated with carcinogenesis of oral squamous epithelium and consistent with cell competition. Med Mol Morphol (2014) 0.75

Targeting Platelets for the Treatment of Cancer. Cancers (Basel) (2017) 0.75

Articles by these authors

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer. Int J Clin Oncol (2011) 5.39

Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging: a multicenter randomized controlled trial. J Clin Oncol (2010) 3.64

Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. Cancer Res (2009) 3.50

Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet (2003) 3.38

Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer. Int J Clin Oncol (2015) 2.70

Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res (2007) 2.39

Predominant infiltration of macrophages and CD8(+) T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer. Cancer (2008) 2.32

Pleomorphic carcinoma of the lung: clinicopathologic characteristics of 70 cases. Am J Surg Pathol (2008) 2.22

Binding mode prediction and inhibitor design of anti-influenza virus diketo acids targeting metalloenzyme RNA polymerase by molecular docking. Bioinformation (2011) 2.14

Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer. J Thorac Cardiovasc Surg (2005) 2.07

Prognostic impact of intratumoural microvascular invasion and microlymphatic permeation on node-negative non-small-cell lung cancer: which indicator is the stronger prognostic factor? Eur J Cardiothorac Surg (2012) 2.04

Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction. Biochem Biophys Res Commun (2003) 2.00

Impact of extratumoral lymphatic permeation on postoperative survival of non-small-cell lung cancer patients. J Thorac Oncol (2014) 1.97

Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. J Biol Chem (2008) 1.92

Comparison of HER2 gene amplification assessed by fluorescence in situ hybridization and HER2 protein expression assessed by immunohistochemistry in gastric cancer. Oncol Rep (2006) 1.91

Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome. Cancer Sci (2008) 1.87

Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice. Arterioscler Thromb Vasc Biol (2009) 1.82

Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression. Int J Cancer (2009) 1.80

Risk factors for tumor recurrence in patients with early-stage (stage I and II) non-small cell lung cancer: patient selection criteria for adjuvant chemotherapy according to the seventh edition TNM classification. Chest (2011) 1.76

Impact of expression of human epidermal growth factor receptors EGFR and ERBB2 on survival in stage II/III gastric cancer. Clin Cancer Res (2012) 1.74

Histopathologic prognostic factors in resected colorectal lung metastases. Ann Thorac Surg (2005) 1.71

The clinical outcome of non-small cell lung cancer patients with adjacent lobe invasion: the optimal classification according to the status of the interlobar pleura at the invasion point. Eur J Cardiothorac Surg (2012) 1.69

Efficacy of capillary pattern type IIIA/IIIB by magnifying narrow band imaging for estimating depth of invasion of early colorectal neoplasms. BMC Gastroenterol (2010) 1.68

Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cells. Blood (2008) 1.66

Glypican-3 expression is correlated with poor prognosis in hepatocellular carcinoma. Cancer Sci (2009) 1.64

Peritoneal elastic laminal invasion of colorectal cancer: the diagnostic utility and clinicopathologic relationship. Am J Surg Pathol (2010) 1.60

Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma. Int J Cancer (2008) 1.59

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59

Prognostic significance of a solid component in pulmonary adenocarcinoma. Ann Thorac Surg (2011) 1.59

Pathological diagnostic criterion of blood and lymphatic vessel invasion in colorectal cancer: a framework for developing an objective pathological diagnostic system using the Delphi method, from the Pathology Working Group of the Japanese Society for Cancer of the Colon and Rectum. J Clin Pathol (2013) 1.57

Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer. Clin Cancer Res (2004) 1.54

Nicardipine vs. saline injection as treatment for Peyronie's disease: a prospective, randomized, single-blind trial. J Sex Med (2010) 1.53

Influence of cigarette smoking on survival and tumor invasiveness in clinical stage IA lung adenocarcinoma. Ann Thorac Surg (2012) 1.44

Primary gastric choriocarcinoma: two case reports and a pooled analysis of 53 cases. Gastric Cancer (2005) 1.44

Immunohistochemical detection of CD133 expression in colorectal cancer: a clinicopathological study. Cancer Sci (2008) 1.42

Effect of prostate volume on tumor grade in patients undergoing radical prostatectomy in the era of extended prostatic biopsies. J Urol (2007) 1.41

Localized pure ground-glass opacity on high-resolution CT: histologic characteristics. J Comput Assist Tomogr (2002) 1.41

Practical utility and objectivity: does evaluation of peritoneal elastic laminal invasion in colorectal cancer overcome these contrary problems? Am J Surg Pathol (2014) 1.40

Primary signet-ring cell carcinoma of the colon at early stage: a case report and a review of the literature. World J Gastroenterol (2006) 1.38

Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. Cancer Res (2003) 1.35

Clinicopathologic characteristics of peripheral squamous cell carcinoma of the lung. Am J Surg Pathol (2003) 1.35

Predictive markers for late cervical metastasis in stage I and II invasive squamous cell carcinoma of the oral tongue. Clin Cancer Res (2004) 1.32

In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions. Stem Cells (2005) 1.31

Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3. Cancer Res (2004) 1.29

Natural killer T cells accelerate atherogenesis in mice. Blood (2004) 1.28

Immunohistochemical expression of BCRP and ERCC1 in biopsy specimen predicts survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy. Lung Cancer (2008) 1.27

Podoplanin-positive fibroblasts enhance lung adenocarcinoma tumor formation: podoplanin in fibroblast functions for tumor progression. Cancer Res (2011) 1.26

Nonrandomized comparison between definitive chemoradiotherapy and radical surgery in patients with T(2-3)N(any) M(0) squamous cell carcinoma of the esophagus. Int J Radiat Oncol Biol Phys (2003) 1.25

Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head. Cancer Sci (2012) 1.25

Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance. PLoS One (2012) 1.21

Autoimmune pancreatitis (AIP) type 1 and type 2: an international consensus study on histopathologic diagnostic criteria. Pancreas (2011) 1.21

Mutational status of EGFR and KIT in thymoma and thymic carcinoma. Lung Cancer (2008) 1.21

CD44 signaling through focal adhesion kinase and its anti-apoptotic effect. FEBS Lett (2002) 1.20

Long-term survival in two cases of resected gastric metastasis of pulmonary pleomorphic carcinoma. J Thorac Oncol (2008) 1.20

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis. J Thorac Oncol (2014) 1.19

Expression profiles of HER2, EGFR, MET and FGFR2 in a large cohort of patients with gastric adenocarcinoma. Gastric Cancer (2014) 1.19

Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer. Gastrointest Endosc (2011) 1.18

Epigenetic regulation of ARHI in breast and ovarian cancer cells. Ann N Y Acad Sci (2003) 1.18

Sequence-dependent conformational energy of DNA derived from molecular dynamics simulations: toward understanding the indirect readout mechanism in protein-DNA recognition. J Am Chem Soc (2005) 1.18

Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry. Metabolomics (2012) 1.17

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. Cancer Sci (2008) 1.17

Circulating microRNA-126 in patients with coronary artery disease: correlation with LDL cholesterol. Thromb J (2012) 1.17

Expression of podoplanin, CD44, and p63 in squamous cell carcinoma of the lung. Cancer Sci (2009) 1.15

Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formation. Int J Cancer (2010) 1.15

Expression of breast cancer resistance protein is associated with a poor clinical outcome in patients with small-cell lung cancer. Lung Cancer (2008) 1.14

Microsatellite instability and protein expression of the DNA mismatch repair gene, hMLH1, of lung cancer in chromate-exposed workers. Mol Carcinog (2005) 1.13

Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability. Biochem Biophys Res Commun (2005) 1.13

Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice. J Biol Chem (2002) 1.13

A nomogram for predicting low-volume/low-grade prostate cancer: a tool in selecting patients for active surveillance. Cancer (2007) 1.13

Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma. J Thorac Oncol (2010) 1.12

Prognostic significance of fibrotic focus in invasive ductal carcinoma of the breast: a prospective observational study. Mod Pathol (2002) 1.12

Human vascular adventitial fibroblasts contain mesenchymal stem/progenitor cells. Biochem Biophys Res Commun (2008) 1.11

Optimal colorectal cancer staging criteria in TNM classification. J Clin Oncol (2012) 1.11