Published in Infect Immun on June 09, 2008
Listeria monocytogenes - from saprophyte to intracellular pathogen. Nat Rev Microbiol (2009) 2.80
Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection. MBio (2013) 1.44
Glutathione activates virulence gene expression of an intracellular pathogen. Nature (2015) 1.20
Integrative genomic analysis identifies isoleucine and CodY as regulators of Listeria monocytogenes virulence. PLoS Genet (2012) 1.14
Clinical development of Listeria monocytogenes-based immunotherapies. Semin Oncol (2012) 0.95
Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria. PLoS Pathog (2009) 0.93
Cellular vaccines in listeriosis: role of the Listeria antigen GAPDH. Front Cell Infect Microbiol (2014) 0.89
An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression. PLoS Pathog (2016) 0.88
The Listeria monocytogenes hibernation-promoting factor is required for the formation of 100S ribosomes, optimal fitness, and pathogenesis. J Bacteriol (2014) 0.86
Membrane chaperone SecDF plays a role in the secretion of Listeria monocytogenes major virulence factors. J Bacteriol (2013) 0.86
Phagosomes induced by cytokines function as anti-Listeria vaccines: novel role for functional compartmentalization of STAT-1 protein and cathepsin-D. J Biol Chem (2012) 0.85
Listeria monocytogenes MDR transporters are involved in LTA synthesis and triggering of innate immunity during infection. Front Cell Infect Microbiol (2014) 0.85
Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA. Clin Vaccine Immunol (2011) 0.83
The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion. Elife (2015) 0.81
The intact structural form of LLO in endosomes cannot protect against listeriosis. Int J Biochem Mol Biol (2011) 0.80
L-glutamine Induces Expression of Listeria monocytogenes Virulence Genes. PLoS Pathog (2017) 0.79
An Effective Counterselection System for Listeria monocytogenes and Its Use To Characterize the Monocin Genomic Region of Strain 10403S. Appl Environ Microbiol (2017) 0.77
A self-help program for memory CD8+ T cells: positive feedback via CD40-CD40L signaling as a critical determinant of secondary expansion. PLoS One (2013) 0.77
Attenuated Listeria monocytogenes vectors overcome suppressive plasma factors during HIV infection to stimulate myeloid dendritic cells to promote adaptive immunity and reactivation of latent virus. AIDS Res Hum Retroviruses (2015) 0.77
Listeria monocytogenes Induced Cell Death Inhibits the Generation of Cell-Mediated Immunity. Infect Immun (2016) 0.76
YopE specific CD8+ T cells provide protection against systemic and mucosal Yersinia pseudotuberculosis infection. PLoS One (2017) 0.75
Metabolic genetic screens reveal multidimensional regulation of virulence gene expression in Listeria monocytogenes, and an aminopeptidase that is critical for PrfA protein activation. Infect Immun (2017) 0.75
Listeria pathogenesis and molecular virulence determinants. Clin Microbiol Rev (2001) 10.41
Immune responses to Listeria monocytogenes. Nat Rev Immunol (2004) 5.91
Dual roles of plcA in Listeria monocytogenes pathogenesis. Mol Microbiol (1993) 5.46
Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors. J Bacteriol (2002) 4.75
A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus. Nat Biotechnol (2006) 4.52
CD8+ T cell effector mechanisms in resistance to infection. Annu Rev Immunol (2000) 4.22
Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci U S A (1996) 4.11
Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc Natl Acad Sci U S A (2002) 3.85
Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity (2007) 3.58
A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes. EMBO J (1999) 3.29
The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. J Cell Biol (2002) 3.01
Gene Designer: a synthetic biology tool for constructing artificial DNA segments. BMC Bioinformatics (2006) 2.85
Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity. Proc Natl Acad Sci U S A (1995) 2.66
Listeriosis. Clin Infect Dis (1997) 2.38
Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity. Nat Med (2005) 2.28
Listeria-based cancer vaccines that segregate immunogenicity from toxicity. Proc Natl Acad Sci U S A (2004) 2.27
A Gly145Ser substitution in the transcriptional activator PrfA causes constitutive overexpression of virulence factors in Listeria monocytogenes. J Bacteriol (1997) 1.91
Extending the host range of Listeria monocytogenes by rational protein design. Cell (2007) 1.76
AIDS research. Did Merck's failed HIV vaccine cause harm? Science (2007) 1.71
How the bacterial pathogen Listeria monocytogenes mediates the switch from environmental Dr. Jekyll to pathogenic Mr. Hyde. Infect Immun (2006) 1.69
The PrfA virulence regulon. Microbes Infect (2007) 1.69
Listeria monocytogenes mutants that fail to compartmentalize listerolysin O activity are cytotoxic, avirulent, and unable to evade host extracellular defenses. Infect Immun (2003) 1.61
Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products. Mol Microbiol (2003) 1.51
Intracellular induction of Listeria monocytogenes actA expression. Infect Immun (2002) 1.49
Bridging the knowledge gaps in vaccine design. Nat Biotechnol (2007) 1.39
AIDS research. Promising AIDS vaccine's failure leaves field reeling. Science (2007) 1.38
Safety and shedding of an attenuated strain of Listeria monocytogenes with a deletion of actA/plcB in adult volunteers: a dose escalation study of oral inoculation. Infect Immun (2002) 1.33
Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infect Immun (2006) 1.29
New Listeria monocytogenes prfA* mutants, transcriptional properties of PrfA* proteins and structure-function of the virulence regulator PrfA. Mol Microbiol (2004) 1.25
Vaccination with irradiated Listeria induces protective T cell immunity. Immunity (2006) 1.23
Listeria monocytogenes as a vaccine vector: virulence attenuation or existing antivector immunity does not diminish therapeutic efficacy. J Immunol (2004) 1.22
A novel mutation within the central Listeria monocytogenes regulator PrfA that results in constitutive expression of virulence gene products. J Bacteriol (2004) 1.18
Pleiotropic enhancement of bacterial pathogenesis resulting from the constitutive activation of the Listeria monocytogenes regulatory factor PrfA. Infect Immun (2005) 1.11
CD8(+)-T-cell response to secreted and nonsecreted antigens delivered by recombinant Listeria monocytogenes during secondary infection. Infect Immun (2002) 1.09
Identification of novel Listeria monocytogenes secreted virulence factors following mutational activation of the central virulence regulator, PrfA. Infect Immun (2007) 1.09
Listeria-based vaccines for cancer treatment. Curr Opin Mol Ther (2005) 1.03
Listeria as a vaccine vector. Microbes Infect (2007) 1.02
Listeriolysin O-deficient Listeria monocytogenes as a vaccine delivery vehicle: antigen-specific CD8 T cell priming and protective immunity. J Immunol (2006) 1.02
Existing antilisterial immunity does not inhibit the development of a Listeria monocytogenes-specific primary cytotoxic T-lymphocyte response. Infect Immun (1999) 0.98
Rhesus macaques with high levels of vaccine induced IFN-gamma producing cells better control viral set-point following challenge with SIV239. Vaccine (2005) 0.98
The induction of HIV Gag-specific CD8+ T cells in the spleen and gut-associated lymphoid tissue by parenteral or mucosal immunization with recombinant Listeria monocytogenes HIV Gag. J Immunol (2003) 0.95
Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease. J Immunol (2007) 0.94
Stimulation of enhanced CD8 T cell responses following immunization with a hyper-antigen secreting intracytosolic bacterial pathogen. J Immunol (2008) 0.84
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature (2003) 10.16
Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. J Exp Med (2004) 3.94
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature (2005) 3.81
Dynamic programming of CD8+ T lymphocyte responses. Nat Immunol (2003) 3.73
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat Med (2006) 3.49
Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host Microbe (2010) 3.09
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood (2007) 2.93
Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria. Proc Natl Acad Sci U S A (2008) 2.62
Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster. Cell Microbiol (2003) 2.34
Listeria-based cancer vaccines that segregate immunogenicity from toxicity. Proc Natl Acad Sci U S A (2004) 2.27
Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib. Clin Cancer Res (2012) 2.25
Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice. J Biol Chem (2007) 2.22
Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity. Cell Microbiol (2004) 1.89
Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways. Nat Med (2002) 1.88
γδ T cells exhibit multifunctional and protective memory in intestinal tissues. Immunity (2013) 1.85
Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway. Immunity (2006) 1.78
CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease. J Neuroimmune Pharmacol (2012) 1.78
A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune induction. Clin Cancer Res (2011) 1.78
How the bacterial pathogen Listeria monocytogenes mediates the switch from environmental Dr. Jekyll to pathogenic Mr. Hyde. Infect Immun (2006) 1.69
Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity. Proc Natl Acad Sci U S A (2008) 1.63
An alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector. J Virol (2003) 1.56
Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products. Mol Microbiol (2003) 1.51
Virus-based vectors for human vaccine applications. Drug Discov Today (2002) 1.51
Intracellular induction of Listeria monocytogenes actA expression. Infect Immun (2002) 1.49
Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity. Proc Natl Acad Sci U S A (2011) 1.37
NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses. Blood (2009) 1.29
Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infect Immun (2006) 1.29
Selective targeting of antitumor immune responses with engineered live-attenuated Listeria monocytogenes. Cancer Res (2006) 1.25
Listeria monocytogenes as a vaccine vector: virulence attenuation or existing antivector immunity does not diminish therapeutic efficacy. J Immunol (2004) 1.22
Synergistic effect of a granulocyte-macrophage colony-stimulating factor-transduced tumor vaccine and systemic interleukin-2 in the treatment of murine colorectal cancer hepatic metastases. Ann Surg Oncol (2003) 1.18
A novel mutation within the central Listeria monocytogenes regulator PrfA that results in constitutive expression of virulence gene products. J Bacteriol (2004) 1.18
CD8+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells. PLoS One (2010) 1.18
Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells. J Immunol (2005) 1.17
Mutations in RRM4 uncouple the splicing repression and RNA-binding activities of polypyrimidine tract binding protein. RNA (2002) 1.15
Pleiotropic enhancement of bacterial pathogenesis resulting from the constitutive activation of the Listeria monocytogenes regulatory factor PrfA. Infect Immun (2005) 1.11
Identification of novel Listeria monocytogenes secreted virulence factors following mutational activation of the central virulence regulator, PrfA. Infect Immun (2007) 1.09
Evidence implicating the 5' untranslated region of Listeria monocytogenes actA in the regulation of bacterial actin-based motility. Cell Microbiol (2004) 1.08
The posttranslocation chaperone PrsA2 contributes to multiple facets of Listeria monocytogenes pathogenesis. Infect Immun (2009) 1.06
Optimizing the balance between host and environmental survival skills: lessons learned from Listeria monocytogenes. Future Microbiol (2012) 1.06
Functional impact of mutational activation on the Listeria monocytogenes central virulence regulator PrfA. Microbiology (2008) 1.05
Constitutive activation of PrfA tilts the balance of Listeria monocytogenes fitness towards life within the host versus environmental survival. PLoS One (2010) 1.03
The virulence regulator PrfA promotes biofilm formation by Listeria monocytogenes. J Bacteriol (2010) 1.01
Listeria monocytogenes CtaP is a multifunctional cysteine transport-associated protein required for bacterial pathogenesis. Mol Microbiol (2009) 0.99
Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol (2012) 0.97
Contribution of chitinases to Listeria monocytogenes pathogenesis. Appl Environ Microbiol (2010) 0.96
Promises and challenges for the development of Listeria monocytogenes-based immunotherapies. Expert Rev Vaccines (2008) 0.96
Functional analysis of the Listeria monocytogenes secretion chaperone PrsA2 and its multiple contributions to bacterial virulence. Mol Microbiol (2011) 0.96
Priming and activation of human ovarian and breast cancer-specific CD8+ T cells by polyvalent Listeria monocytogenes-based vaccines. J Immunother (2009) 0.95
A novel prfA mutation that promotes Listeria monocytogenes cytosol entry but reduces bacterial spread and cytotoxicity. Microb Pathog (2008) 0.95
Clinical development of Listeria monocytogenes-based immunotherapies. Semin Oncol (2012) 0.95
Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease. J Immunol (2007) 0.94
Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria. PLoS Pathog (2009) 0.93
Listeria monocytogenes PrsA2 is required for virulence factor secretion and bacterial viability within the host cell cytosol. Infect Immun (2010) 0.92
The second extracellular loop dictates Occludin-mediated HCV entry. Virology (2010) 0.92
Impact of preexisting vector-specific immunity on vaccine potency: characterization of listeria monocytogenes-specific humoral and cellular immunity in humans and modeling studies using recombinant vaccines in mice. Infect Immun (2009) 0.91
Cutting edge: a crucial role for B7-CD28 in transmitting T help from APC to CTL. J Immunol (2002) 0.91
The Listeria monocytogenes ChiA chitinase enhances virulence through suppression of host innate immunity. MBio (2013) 0.90
Virological and preclinical characterization of a dendritic cell targeting, integration-deficient lentiviral vector for cancer immunotherapy. J Immunother (2015) 0.89
Increased survival in sepsis by in vivo adenovirus-induced expression of IL-10 in dendritic cells. J Immunol (2002) 0.89
The ubiquitin-like protein PLIC-1 or ubiquilin 1 inhibits TLR3-Trif signaling. PLoS One (2011) 0.88
KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity. J Clin Invest (2008) 0.88
Evidence for subpopulations of Listeria monocytogenes with enhanced invasion of cardiac cells. J Med Microbiol (2011) 0.87
Selected prfA* mutations in recombinant attenuated Listeria monocytogenes strains augment expression of foreign immunogens and enhance vaccine-elicited humoral and cellular immune responses. Infect Immun (2008) 0.87
Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax. Infect Immun (2009) 0.87
Probing the role of protein surface charge in the activation of PrfA, the central regulator of Listeria monocytogenes pathogenesis. PLoS One (2011) 0.86
Killed but metabolically active vaccines. Curr Opin Biotechnol (2012) 0.85
Negative regulation of PrfA, the key activator of Listeria monocytogenes virulence gene expression, is dispensable for bacterial pathogenesis. Microbiology (2003) 0.85
Duration of CTL activation regulates IL-2 production required for autonomous clonal expansion. Eur J Immunol (2006) 0.85
Vesicular stomatitis virus: an exciting new therapeutic oncolytic virus candidate for cancer or just another chapter from Field's Virology? Cancer Cell (2003) 0.84
Differential expression of miRNAs in response to topping in flue-cured tobacco (Nicotiana tabacum) roots. PLoS One (2011) 0.84
Stimulation of enhanced CD8 T cell responses following immunization with a hyper-antigen secreting intracytosolic bacterial pathogen. J Immunol (2008) 0.84