Increased fatty acid synthase as a potential therapeutic target in multiple myeloma.

Fatty acid synthase as a potential therapeutic target in cancer. Future Oncol (2010) 2.00

Inhibition of fatty acid metabolism reduces human myeloma cells proliferation. PLoS One (2012) 0.91

Blockade of fatty acid synthase triggers significant apoptosis in mantle cell lymphoma. PLoS One (2012) 0.86

Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone. Front Endocrinol (Lausanne) (2016) 0.77

Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma. Clin Cancer Res (2016) 0.75

FASN and CD36 predict survival in rituximab-treated diffuse large B-cell lymphoma. J Hematop (2013) 0.75

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med (2003) 8.93

Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer (2002) 5.30

Energy deregulation: licensing tumors to grow. Science (2006) 2.31

Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep (2001) 2.04

Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia. Am J Pathol (1997) 1.93

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells. Proc Natl Acad Sci U S A (2004) 1.77

Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival. Hum Pathol (1997) 1.76

Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer. Int J Cancer (2002) 1.65

Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression. Prostate (2001) 1.32

Expression of fatty acid synthase as a prognostic indicator in soft tissue sarcomas. Clin Cancer Res (2003) 1.18

Fatty acid synthase-catalyzed de novo fatty acid biosynthesis: from anabolic-energy-storage pathway in normal tissues to jack-of-all-trades in cancer cells. Arch Immunol Ther Exp (Warsz) (2004) 1.17

Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patients. Cancer Lett (2001) 1.10

Increased fatty acid synthase is a therapeutic target in mesothelioma. Clin Cancer Res (2001) 0.97

Expression of the lipogenic enzyme fatty acid synthase (FAS) in retinoblastoma and its correlation with tumor aggressiveness. Invest Ophthalmol Vis Sci (2003) 0.93

Key role of mitochondria in cerulenin-mediated apoptosis. Cell Death Differ (2002) 0.89

[Cerulenin changes apoptosis related genes expression in multiple myeloma cell line U266]. Zhonghua Xue Ye Xue Za Zhi (2007) 0.78

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. Cell (2010) 3.04

Characteristics of Chinese patients with Wegener's granulomatosis with anti-myeloperoxidase autoantibodies. Kidney Int (2005) 2.07

Effect of varying CT section width on volumetric measurement of lung tumors and application of compensatory equations. Radiology (2003) 1.80

Implementation and evaluation of various demons deformable image registration algorithms on a GPU. Phys Med Biol (2010) 1.79

Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle. Mol Cell Biol (2003) 1.61

Developing DCE-CT to quantify intra-tumor heterogeneity in breast tumors with differing angiogenic phenotype. IEEE Trans Med Imaging (2009) 1.58

The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancy. Proc Natl Acad Sci U S A (2009) 1.48

A rat model of chronic kidney disease-mineral bone disorder. Kidney Int (2008) 1.45

Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia. Blood (2005) 1.29

Normal tissue complication probability modeling of acute hematologic toxicity in cervical cancer patients treated with chemoradiotherapy. Int J Radiat Oncol Biol Phys (2010) 1.22

Characteristics and prognosis of Chinese patients with anti-glomerular basement membrane disease. Nephron Clin Pract (2004) 1.14

Technical aspects of imaging and transfemoral arterial treatment of N1-S1 tumors in rats: an appropriate model to test the biology and therapeutic response to transarterial treatments of liver cancers. J Vasc Interv Radiol (2009) 1.04

The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesis. J Biol Chem (2010) 1.04

Ki-67 is a valuable prognostic predictor of lymphoma but its utility varies in lymphoma subtypes: evidence from a systematic meta-analysis. BMC Cancer (2014) 1.04

Serologic survey of the sentinel animals for plague surveillance and screening for complementary diagnostic markers to F1 antigen by protein microarray. Am J Trop Med Hyg (2008) 1.01

Protein-to-creatinine ratio in spot urine samples as a predictor of quantitation of proteinuria. Clin Chim Acta (2004) 0.99

Correlation between radiation dose to ¹⁸F-FDG-PET defined active bone marrow subregions and acute hematologic toxicity in cervical cancer patients treated with chemoradiotherapy. Int J Radiat Oncol Biol Phys (2012) 0.97

Kinetochore dynein generates a poleward pulling force to facilitate congression and full chromosome alignment. Cell Res (2007) 0.97

Gut microbiota dysbiosis and bacterial community assembly associated with cholesterol gallstones in large-scale study. BMC Genomics (2013) 0.96

Normoalbuminaemia is associated with IgA nephropathy in primary glomerulopathy with nephrotic-range proteinuria in Chinese patients. Nephrol Dial Transplant (2010) 0.95

Spatial variation of Yersinia pestis from Yunnan Province of China. Am J Trop Med Hyg (2009) 0.94

[Clinical and pathological features of anti-neutrophil cytoplasm antibody associated systemic vasculitis in children]. Zhonghua Er Ke Za Zhi (2003) 0.93

X-ray CT high-density artefact suppression in the presence of bones. Phys Med Biol (2004) 0.93

Th22, but not Th17 might be a good index to predict the tissue involvement of systemic lupus erythematosus. J Clin Immunol (2013) 0.93

Acute kidney injury and bilateral symmetrical enlargement of the kidneys as first presentation of B-cell lymphoblastic lymphoma. Am J Kidney Dis (2012) 0.93

The prevalence and target antigens of antithyroid drugs induced antineutrophil cytoplasmic antibodies (ANCA) in Chinese patients with hyperthyroidism. Endocr Res (2004) 0.92

Natural anti-GBM antibodies from normal human sera recognize alpha3(IV)NC1 restrictively and recognize the same epitopes as anti-GBM antibodies from patients with anti-GBM disease. Clin Immunol (2007) 0.90

Berbamine exhibits potent antitumor effects on imatinib-resistant CML cells in vitro and in vivo. Acta Pharmacol Sin (2009) 0.90

Palladium-catalyzed decarboxylative coupling of allylic alkynoates with arynes. Org Lett (2009) 0.88

Disease stage characterization of hepatorenal fibrocystic pathology in the PCK rat model of ARPKD. Anat Rec (Hoboken) (2010) 0.88

The epidemiological analyses of trauma patients in Chongqing teaching hospitals following the Wenchuan earthquake. Injury (2009) 0.87

Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity. J Zhejiang Univ Sci B (2011) 0.87

Physiological role of the interaction between CARMIL1 and capping protein. Mol Biol Cell (2013) 0.86

Optimization of hybrid iterative reconstruction level in pediatric body CT. AJR Am J Roentgenol (2014) 0.85

The level of serum secretory IgA of patients with IgA nephropathy is elevated and associated with pathological phenotypes. Nephrol Dial Transplant (2007) 0.85

Effect of different LLLT on pituitrin-induced bradycardia in the rabbit. Lasers Med Sci (2006) 0.85

Selective synthesis of spiro[4,5]trienyl acetates via an intramolecular electrophilic ipso-iodocyclization process. Org Lett (2008) 0.83

Cycloaddition of arynes with iodonium ylides: a mild and general route for the synthesis of benzofuran derivatives. Org Lett (2008) 0.83

Sequential intermolecular aminopalladation/ortho-arene C-H activation reactions of N-phenylpropiolamides with phthalimide. Org Lett (2008) 0.83

Expression of S100B protein levels in serum and cerebrospinal fluid with different forms of neuropsychiatric systemic lupus erythematosus. Clin Rheumatol (2007) 0.83

Effect of tube voltage on CT noise levels in different phantom sizes. AJR Am J Roentgenol (2013) 0.83

Efficient palladium-catalyzed homocoupling reaction and Sonogashira cross-coupling reaction of terminal alkynes under aerobic conditions. J Org Chem (2005) 0.82

Identification of haplotype tag single nucleotide polymorphisms within the receptor for advanced glycation end products gene and their clinical relevance in patients with major trauma. Crit Care (2012) 0.82

Dosimetric comparison study between intensity modulated radiation therapy and three-dimensional conformal proton therapy for pelvic bone marrow sparing in the treatment of cervical cancer. J Appl Clin Med Phys (2010) 0.82

Selective synthesis of o-acylbenzylphosphonates by insertion reactions of arynes into beta-ketophosphonates. J Org Chem (2009) 0.82

Monitoring the longitudinal intra-tumor physiological impulse response to VEGFR2 blockade in breast tumors using DCE-CT. Mol Imaging Biol (2011) 0.81

Evaluation of a pig femoral head osteonecrosis model. J Orthop Surg Res (2010) 0.81

[Characteristics of re-suspended road dust and its significant effect on the airborne particulate pollution in Beijing]. Huan Jing Ke Xue (2009) 0.81

The heparin binding motif of endostatin mediates its interaction with receptor nucleolin. Biochemistry (2009) 0.81

[Effects of berbamine on growth of leukemia cell line NB4 and its mechanism]. Zhejiang Da Xue Xue Bao Yi Xue Ban (2006) 0.81

[Connective tissue growth factor promotes the proliferation of myofibroblast through Erk-1/2 signaling pathway]. Zhonghua Yi Xue Za Zhi (2005) 0.80

[The significance of urinary podocytes in patients with active lupus nephritis]. Zhonghua Nei Ke Za Zhi (2007) 0.80

Synthesis of (E)-3-(isobenzofuran-3(1H)-ylidene)indolin-2-ones by the palladium-catalyzed intramolecular C-H functionalization process. J Org Chem (2009) 0.80

Interferon alpha on expression of hTERT mRNA in peripheral blood mononuclear cells of patients with chronic hepatitis B. Clin Dev Immunol (2011) 0.80

Fundamentals of multichannel CT. Radiol Clin North Am (2003) 0.80

[Efficacy and safety of low-dose cyclophosphamide plus corticosteroids for type I/II myasthenia gravis]. Zhonghua Yi Xue Za Zhi (2012) 0.80

[Following-up of nosocomial lower respiratory infection in patients with hematological malignancy after chemotherapy]. Zhonghua Yu Fang Yi Xue Za Zhi (2008) 0.79

[Peritubular capillary injury in Chinese herb guan-mu-tong-induced acute tubular necrosis]. Zhonghua Nei Ke Za Zhi (2005) 0.79

[Analysis of clinical factors affecting pregnancy rate of intrauterine insemination]. Beijing Da Xue Xue Bao (2013) 0.79

The antiproliferation effect of berbamine on k562 resistant cells by inhibiting NF-kappaB pathway. Anat Rec (Hoboken) (2009) 0.79

[Overexpression of Shp-2 is associated with the unlimited growth and apoptosis resistance of p210 bcr-abl-mediated chronic myeloid leukemia]. Zhonghua Yi Xue Za Zhi (2005) 0.79

Identification of haplotype tag SNPs within the whole myeloid differentiation 2 gene and their clinical relevance in patients with major trauma. Shock (2012) 0.79

[Distribution of IgG subclass of anti-myeloperoxidase antibodies in sera from patients with propylthiouracil induced vasculitis]. Zhonghua Yi Xue Za Zhi (2004) 0.78

Effect of prenatal alcohol exposure on bony craniofacial development: a mouse MicroCT study. Alcohol (2013) 0.78

[Effect of subanaesthetic dose of ketamine on mechanical stimulus on brain regions]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2013) 0.78

Arctigenin induces apoptosis in colon cancer cells through ROS/p38MAPK pathway. J BUON (2016) 0.77

Simple and Sensitive Discrimination of Amino Acids with Functionalized Silver Nanoparticles. ACS Comb Sci (2015) 0.77

[Variable number of tandem repeats polymorphism of MUC20 is associated with the progression of IgA nephropathy]. Zhonghua Yi Xue Za Zhi (2005) 0.77

Palladium-catalyzed annulations of arynes with 2-(2-iodophenoxy)-1-substituted ethanones. Chem Commun (Camb) (2010) 0.77

[Effect of functionalized multi-walled carbon nanotubes on L02 cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2010) 0.77

Sulfate stabilizes the folding intermediate more than the native structure of endostatin. Arch Biochem Biophys (2008) 0.77

Novel distribution pattern of fibrinolytic components in rabbit tissues extract: a preliminary study. J Zhejiang Univ Sci B (2007) 0.77

X-ray CT high-density artefact suppression in cryosurgery. Phys Med Biol (2002) 0.77

Construction of benzosiloles, six- and eight-membered silacyclic skeletons, via a Pd-catalyzed intramolecular Mizoroki-Heck reaction of vinylsilanes. Org Lett (2012) 0.77

[Neural apoptosis and apoptosis-related genes in intracerebral hemorrhage patients]. Zhonghua Yi Xue Za Zhi (2006) 0.77

[Relationship between drug resistance and the expression of NF-kappaB induced in leukemic cells]. Zhejiang Da Xue Xue Bao Yi Xue Ban (2004) 0.77

[Role of target controlled infusion of remifentanil for the prevention of etomidate induced myoclonus during general anesthesia]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2013) 0.77

Three-dimensional reconstruction of maxillae using spiral computed tomography and its application in postoperative adult patients with unilateral complete cleft lip and palate. J Oral Maxillofac Surg (2011) 0.77

The determinants of GP visits in New Zealand. Aust N Z J Public Health (2010) 0.77

Palladium-catalyzed cyclocarbonylation of arynes with methyl allyl carbonates: selective synthesis of 1H-inden-1-ones. J Org Chem (2010) 0.77

Reusable copper-catalyzed cross-coupling reactions of aryl halides with organotins in inexpensive ionic liquids. J Org Chem (2006) 0.77

Iron-catalyzed annulations of 2-(2-alkynyl)phenoxy)-1-arylethanones leading to substituted naphthalen-1-ols. Chem Commun (Camb) (2009) 0.77

[Response to thymectomy and analysis of influencing factors in the treatment of children with myasthenia gravis]. Zhonghua Yi Xue Za Zhi (2012) 0.76

[High glucose regulates the production of MMP-9 in podocyte through ERK1/2 signal pathway]. Zhonghua Yi Xue Za Zhi (2005) 0.76

[A case-control study on green tea consumption and the risk of adult leukemia]. Zhonghua Liu Xing Bing Xue Za Zhi (2008) 0.76

WASP, Tregs, and food allergies - rare disease provides insight into a common problem. J Clin Invest (2016) 0.76

Effects of bilateral adrenalectomy on the innate immune responses following trauma in rats. Injury (2011) 0.76

(18)F-NaF PET Imaging of Early Coronary Artery Calcification. JACC Cardiovasc Imaging (2015) 0.76

Functional imaging in small animals using X-ray computed tomography--study of physiologic measurement reproducibility. IEEE Trans Med Imaging (2005) 0.76

[CD4+CD25+high regulatory T cells in patients with autoimmune hepatitis]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi (2007) 0.76

Fundamentals of multichannel CT. Semin Musculoskelet Radiol (2004) 0.75

[Treatment of proliferative lupus nephritis with leflunomide and steroid: a prospective multi-center controlled clinical trial]. Zhonghua Nei Ke Za Zhi (2005) 0.75

Diagnosis and Treatment of Odontogenic Cutaneous Sinus Tracts in an 11-Year-Old Boy: A Case Report. Medicine (Baltimore) (2016) 0.75

Commonality in Down and fetal alcohol syndromes. Birth Defects Res A Clin Mol Teratol (2013) 0.75

Infantile Hepatic Hemangioendothelioma Associated With Congestive Heart Failure: Two Case Reports With Different Outcomes. Medicine (Baltimore) (2015) 0.75

Acceleration of the meckel syndrome by near-infrared light therapy. Nephron Extra (2011) 0.75

[The experimental results of GVHD following orthotropic liver transplantation]. Zhonghua Gan Zang Bing Za Zhi (2009) 0.75

[Measurement of the volume absorption of alveolar bone grafting]. Shanghai Kou Qiang Yi Xue (2012) 0.75