Published in Annu Rev Neurosci on January 01, 2008
Neuroligins and neurexins link synaptic function to cognitive disease. Nature (2008) 9.23
Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron (2011) 4.66
Mechanisms underlying development of visual maps and receptive fields. Annu Rev Neurosci (2008) 4.00
Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. Cell (2009) 2.91
Mechanisms and molecules of neuronal wiring: a primer. Cold Spring Harb Perspect Biol (2011) 2.62
WNT signaling underlies the pathogenesis of neuropathic pain in rodents. J Clin Invest (2013) 2.42
Can we safely target the WNT pathway? Nat Rev Drug Discov (2014) 2.31
A de novo convergence of autism genetics and molecular neuroscience. Trends Neurosci (2013) 2.24
Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes. Genome Biol (2010) 2.20
Synaptic organizing complexes. Curr Opin Neurobiol (2010) 1.80
Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth. J Cell Biol (2011) 1.68
Mitotic and mitogenic Wnt signalling. EMBO J (2012) 1.62
Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms. J Neurosci (2009) 1.59
Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. J Neurosci (2010) 1.57
Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts. PLoS Biol (2013) 1.44
Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses. Proc Natl Acad Sci U S A (2010) 1.39
Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons. J Biol Chem (2009) 1.38
Transcriptome of embryonic and neonatal mouse cortex by high-throughput RNA sequencing. Proc Natl Acad Sci U S A (2009) 1.37
Biosignatures for Parkinson's disease and atypical parkinsonian disorders patients. PLoS One (2012) 1.33
Wnt signaling promotes AChR aggregation at the neuromuscular synapse in collaboration with agrin. Proc Natl Acad Sci U S A (2008) 1.32
Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca²⁺/Calmodulin-dependent protein kinase II. Proc Natl Acad Sci U S A (2011) 1.30
Initiating and growing an axon. Cold Spring Harb Perspect Biol (2010) 1.24
Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis. Development (2010) 1.18
Wnt signaling in the vertebrate central nervous system: from axon guidance to synaptic function. Cold Spring Harb Perspect Biol (2012) 1.18
The plane facts of PCP in the CNS. Neuron (2008) 1.17
WNTs tune up the neuromuscular junction. Nat Rev Neurosci (2009) 1.17
Wnt transmembrane signaling and long-term spatial memory. Hippocampus (2011) 1.14
The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development. Nat Neurosci (2010) 1.13
WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Development (2012) 1.12
Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. Proc Natl Acad Sci U S A (2013) 1.12
Targeting Wnt pathways in disease. Cold Spring Harb Perspect Biol (2012) 1.11
Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton. J Cell Biol (2012) 1.10
Cell adhesion, the backbone of the synapse: "vertebrate" and "invertebrate" perspectives. Cold Spring Harb Perspect Biol (2009) 1.09
Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development (2012) 1.07
WNTs in synapse formation and neuronal circuitry. EMBO J (2012) 1.07
Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence. BMC Neurosci (2010) 1.05
Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons. Mol Neurodegener (2010) 1.05
Collagen XIX is expressed by interneurons and contributes to the formation of hippocampal synapses. J Comp Neurol (2010) 1.02
Wnt/calcium signaling mediates axon growth and guidance in the developing corpus callosum. Dev Neurobiol (2011) 1.01
Extracellular matrix and its receptors in Drosophila neural development. Dev Neurobiol (2011) 0.98
VANG-1 and PRKL-1 cooperate to negatively regulate neurite formation in Caenorhabditis elegans. PLoS Genet (2011) 0.98
WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity. PLoS One (2011) 0.96
Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders. Neurotoxicol Teratol (2012) 0.95
Signaling mechanisms in cortical axon growth, guidance, and branching. Front Neuroanat (2011) 0.95
Reinduced Wnt signaling limits regenerative potential of sensory axons in the spinal cord following conditioning lesion. Proc Natl Acad Sci U S A (2012) 0.94
En1 and Wnt signaling in midbrain dopaminergic neuronal development. Neural Dev (2011) 0.92
Molecular mechanisms of dendrite morphogenesis. Front Cell Neurosci (2012) 0.90
Wnts in action: from synapse formation to synaptic maintenance. Front Cell Neurosci (2013) 0.90
An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation. Dev Biol (2013) 0.90
Regulation of Wnt signaling by nociceptive input in animal models. Mol Pain (2012) 0.90
Brain transcriptome variation among behaviorally distinct strains of zebrafish (Danio rerio). BMC Genomics (2012) 0.89
Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin. Mol Psychiatry (2014) 0.89
Genetic dissection of synaptic specificity. Curr Opin Neurobiol (2010) 0.88
Perlecan regulates bidirectional Wnt signaling at the Drosophila neuromuscular junction. J Cell Biol (2013) 0.88
Toxicogenomic profiling in maternal and fetal rodent brains following gestational exposure to chlorpyrifos. Toxicol Appl Pharmacol (2010) 0.87
Expression of Wnt receptors in adult spiral ganglion neurons: frizzled 9 localization at growth cones of regenerating neurites. Neuroscience (2009) 0.87
Isoform-specific palmitoylation of JNK regulates axonal development. Cell Death Differ (2011) 0.87
Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation. Mol Cell Neurosci (2013) 0.86
Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation. J Neurosci (2013) 0.86
Ultrastructural relationship between the mu opioid receptor and its interacting protein, GPR177, in striatal neurons. Brain Res (2010) 0.85
Ménage à Trio during BMP-Mediated Retrograde Signaling at the NMJ. Neuron (2010) 0.85
WNT5 interacts with the Ryk receptors doughnut and derailed to mediate muscle attachment site selection in Drosophila melanogaster. PLoS One (2012) 0.84
Wnt5a evokes cortical axon outgrowth and repulsive guidance by tau mediated reorganization of dynamic microtubules. Dev Neurobiol (2013) 0.84
The postsynaptic adenomatous polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic synapses in vivo. J Neurosci (2010) 0.84
Retrograde neural circuit specification by target-derived neurotrophins and growth factors. Curr Opin Neurobiol (2010) 0.84
Axon Guidance Molecules and Neural Circuit Remodeling After Spinal Cord Injury. Neurotherapeutics (2016) 0.84
Wnt-signaling and planar cell polarity genes regulate axon guidance along the anteroposterior axis in C. elegans. Dev Neurobiol (2013) 0.83
Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons. Exp Neurol (2011) 0.83
The Wnt and BMP families of signaling morphogens at the vertebrate neuromuscular junction. Int J Mol Sci (2011) 0.82
Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance. Front Cell Neurosci (2013) 0.82
Postsynaptic assembly: a role for Wnt signaling. Dev Neurobiol (2013) 0.81
Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Dev Neurobiol (2014) 0.80
The role of Wnt signaling in the development of Alzheimer's disease: a potential therapeutic target? Biomed Res Int (2014) 0.80
How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario. Front Cell Neurosci (2015) 0.80
How are neurons wired to form functional and plastic circuits? Meeting on Axon Guidance, Synaptogenesis & Neural Plasticity. EMBO Rep (2009) 0.79
Membrane potential depolarization causes alterations in neuron arrangement and connectivity in cocultures. Brain Behav (2014) 0.79
Atypical protein kinase Cι is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2. J Biol Chem (2013) 0.79
The conserved transmembrane RING finger protein PLR-1 downregulates Wnt signaling by reducing Frizzled, Ror and Ryk cell-surface levels in C. elegans. Development (2014) 0.79
Role of wnt signaling in the control of adult hippocampal functioning in health and disease: therapeutic implications. Curr Neuropharmacol (2013) 0.78
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B. Mol Cell Biol (2013) 0.78
Conditioned medium of Wnt/β-catenin signaling-activated olfactory ensheathing cells promotes synaptogenesis and neurite growth in vitro. Cell Mol Neurobiol (2013) 0.78
Calpain activation by Wingless-type murine mammary tumor virus integration site family, member 5A (Wnt5a) promotes axonal growth. J Biol Chem (2010) 0.78
Mutations in Wnt2 alter presynaptic motor neuron morphology and presynaptic protein localization at the Drosophila neuromuscular junction. PLoS One (2010) 0.78
unfulfilled interacting genes display branch-specific roles in the development of mushroom body axons in Drosophila melanogaster. G3 (Bethesda) (2014) 0.77
Wnt and extraocular muscle sparing in amyotrophic lateral sclerosis. Invest Ophthalmol Vis Sci (2014) 0.77
Andrographolide Stimulates Neurogenesis in the Adult Hippocampus. Neural Plast (2015) 0.77
A flanking gene problem leads to the discovery of a Gprc5b splice variant predominantly expressed in C57Bl/6J mouse brain and in maturing neurons. PLoS One (2010) 0.76
MTM-6, a phosphoinositide phosphatase, is required to promote synapse formation in Caenorhabditis elegans. PLoS One (2014) 0.76
Coordinated Action of Biological Processes during Embryogenesis Can Cause Genome-Wide Linkage Disequilibrium in the Human Genome and Influence Age-Related Phenotypes. Ann Gerontol Geriatr Res (2016) 0.75
Analysis of miRNAs Involved in Mouse Brain Damage upon Enterovirus 71 Infection. Front Cell Infect Microbiol (2017) 0.75
Wnt signaling networks in autism spectrum disorder and intellectual disability. J Neurodev Disord (2016) 0.75
Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance. BMC Neurosci (2016) 0.75
Planar polarity genes and inhibition of supernumerary neurites. Worm (2012) 0.75
Lrp5/6 are required for cerebellar development and for suppressing TH expression in Purkinje cells via β-catenin. Mol Brain (2016) 0.75
Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation. Proc Natl Acad Sci U S A (2017) 0.75
Regulation of WNT Signaling at the Neuromuscular Junction by the Immunoglobulin Super-Family Protein RIG-3 in Caenorhabditis elegans. Genetics (2017) 0.75
Alterations in the expression of a neurodevelopmental gene exert long-lasting effects on cognitive-emotional phenotypes and functional brain networks: translational evidence from the stress-resilient Ahi1 knockout mouse. Mol Psychiatry (2016) 0.75
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science (2003) 4.18
Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping. Nature (2006) 2.92
Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract. Nat Neurosci (2005) 2.76
Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. J Neurosci (2010) 1.57
Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Dev Cell (2011) 1.56
Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance. J Neurosci (2008) 1.55
Chronic Hypoxia Increases Intracellular Ca(2+) Concentration via Enhanced Ca(2+) Entry Through Receptor-Operated Ca(2+) Channels in Pulmonary Venous Smooth Muscle Cells. Circ J (2015) 1.41
Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing. Nat Neurosci (2009) 1.37
Repulsive Wnt signaling inhibits axon regeneration after CNS injury. J Neurosci (2008) 1.36
Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation. Neural Dev (2008) 1.23
Navigating intermediate targets: the nervous system midline. Cold Spring Harb Perspect Biol (2010) 1.21
Reinduced Wnt signaling limits regenerative potential of sensory axons in the spinal cord following conditioning lesion. Proc Natl Acad Sci U S A (2012) 0.94
Nicotine-induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol (2012) 0.94
Wnt signaling in neural circuit development. J Neurosci (2005) 0.93
Expression of the Wnt signaling system in central nervous system axon guidance and regeneration. Front Mol Neurosci (2012) 0.90
Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. J Neurosci (2013) 0.88
Wnts and Wnt inhibitors do not influence axon outgrowth from chicken statoacoustic ganglion neurons. Hear Res (2011) 0.86
Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Dev Neurobiol (2014) 0.80
How are neurons wired to form functional and plastic circuits? Meeting on Axon Guidance, Synaptogenesis & Neural Plasticity. EMBO Rep (2009) 0.79
High Density Individually Addressable Nanowire Arrays Record Intracellular Activity from Primary Rodent and Human Stem Cell Derived Neurons. Nano Lett (2017) 0.75
An update on spinal cord injury research. Neurosci Bull (2013) 0.75