Published in BMC Neurosci on March 09, 2010
A unique role of RGS9-2 in the striatum as a positive or negative regulator of opiate analgesia. J Neurosci (2011) 1.09
Wntless is required for peripheral lung differentiation and pulmonary vascular development. Dev Biol (2013) 1.03
Amygdalar peptidergic circuits regulating noradrenergic locus coeruleus neurons: linking limbic and arousal centers. Exp Neurol (2011) 0.95
Wntless in Wnt secretion: molecular, cellular and genetic aspects. Front Biol (Beijing) (2012) 0.89
Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters. Membranes (Basel) (2015) 0.88
Updating the Wnt pathways. Biosci Rep (2014) 0.86
MOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screens. PLoS One (2013) 0.86
Ultrastructural relationship between the mu opioid receptor and its interacting protein, GPR177, in striatal neurons. Brain Res (2010) 0.85
Expression of GPR177 (Wntless/Evi/Sprinter), a highly conserved Wnt-transport protein, in rat tissues, zebrafish embryos, and cultured human cells. Dev Dyn (2010) 0.85
Low expression of D2R and Wntless correlates with high motivation for heroin. Behav Neurosci (2015) 0.83
Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons. Exp Neurol (2011) 0.83
Regulation of M₃ muscarinic receptor expression and function by transmembrane protein 147. Mol Pharmacol (2010) 0.83
Extracellular Calcium-Sensing Receptor Inhibition of Intestinal EpithelialTNF Signaling Requires CaSR-Mediated Wnt5a/Ror2 Interaction. Front Physiol (2011) 0.82
Direct targeting of peptidergic amygdalar neurons by noradrenergic afferents: linking stress-integrative circuitry. Brain Struct Funct (2013) 0.80
Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons. Prog Neuropsychopharmacol Biol Psychiatry (2013) 0.80
Whole-genome expression profile in zebrafish embryos after chronic exposure to morphine: identification of new genes associated with neuronal function and mu opioid receptor expression. BMC Genomics (2014) 0.78
Bioorthogonal click chemistry to assay mu-opioid receptor palmitoylation using 15-hexadecynoic acid and immunoprecipitation. Anal Biochem (2014) 0.77
Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization. Genes Brain Behav (2013) 0.77
Early avoidance of a heroin-paired taste-cue and subsequent addiction-like behavior in rats. Brain Res Bull (2015) 0.77
Case-control association study of WLS variants in opioid and cocaine addicted populations. Psychiatry Res (2013) 0.76
Synaptic activity-regulated Wnt signaling in synaptic plasticity, glial function and chronic pain. CNS Neurol Disord Drug Targets (2014) 0.75
Wntless-Sec12 complex on ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export. J Cell Sci (2017) 0.75
Protein production by auto-induction in high density shaking cultures. Protein Expr Purif (2005) 29.74
The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol (2004) 24.63
Wnt signalling in stem cells and cancer. Nature (2005) 19.26
Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol (1998) 9.24
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature (1996) 7.15
Wnt signalling regulates adult hippocampal neurogenesis. Nature (2005) 6.66
Structural plasticity associated with exposure to drugs of abuse. Neuropharmacology (2004) 6.08
Desensitization of G protein-coupled receptors and neuronal functions. Annu Rev Neurosci (2004) 4.44
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell (2006) 4.09
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell (2006) 4.01
A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo. Proc Natl Acad Sci U S A (1998) 3.62
Morphine activates opioid receptors without causing their rapid internalization. J Biol Chem (1996) 2.99
Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat Neurosci (2004) 2.81
Opioid receptors. Annu Rev Biochem (2004) 2.71
Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat Cell Biol (2008) 2.43
Opiates inhibit neurogenesis in the adult rat hippocampus. Proc Natl Acad Sci U S A (2000) 2.39
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat Cell Biol (2008) 2.38
Wnt signaling in neural circuit assembly. Annu Rev Neurosci (2008) 2.35
Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction. Br J Pharmacol (2008) 1.99
Sprinter: a novel transmembrane protein required for Wg secretion and signaling. Development (2006) 1.98
75 years of opioid research: the exciting but vain quest for the Holy Grail. Br J Pharmacol (2006) 1.91
Clinical pharmacology of opioids for pain. Clin J Pain (2002) 1.85
Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release. J Cell Biol (2006) 1.85
Opioids: cellular mechanisms of tolerance and physical dependence. Curr Opin Pharmacol (2005) 1.82
Wnts: up-and-coming at the synapse. Trends Neurosci (2007) 1.67
Differential activation and trafficking of micro-opioid receptors in brain slices. Mol Pharmacol (2008) 1.49
Wnt signaling in neuroprotection and stem cell differentiation. Prog Neurobiol (2008) 1.46
Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor. J Neurosci (2002) 1.44
Postsynaptic signaling via the [mu]-opioid receptor: responses of dorsal horn neurons to exogenous opioids and noxious stimulation. J Neurosci (2000) 1.44
Helping Wingless take flight: how WNT proteins are secreted. Nat Rev Mol Cell Biol (2007) 1.42
Utilizing the split-ubiquitin membrane yeast two-hybrid system to identify protein-protein interactions of integral membrane proteins. Sci STKE (2005) 1.39
Regulation of Wnt protein secretion and its role in gradient formation. EMBO Rep (2008) 1.35
Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs. Curr Opin Neurobiol (2003) 1.31
Analysis of membrane protein interactions using yeast-based technologies. Trends Biochem Sci (2002) 1.30
Multiple actions of spinophilin regulate mu opioid receptor function. Neuron (2008) 1.30
Dopamine D2 and D3 receptors are linked to the actin cytoskeleton via interaction with filamin A. Proc Natl Acad Sci U S A (2001) 1.29
Interaction between the mu opioid receptor and filamin A is involved in receptor regulation and trafficking. Mol Pharmacol (2003) 1.21
Mu opioid receptor regulation and opiate responsiveness. AAPS J (2005) 1.16
Novel peptidic mu opioid antagonists: pharmacologic characterization in vitro and in vivo. J Pharmacol Exp Ther (1989) 1.13
Role of mPKCI, a novel mu-opioid receptor interactive protein, in receptor desensitization, phosphorylation, and morphine-induced analgesia. Mol Pharmacol (2004) 1.13
Time course of morphine's effects on adult hippocampal subgranular zone reveals preferential inhibition of cells in S phase of the cell cycle and a subpopulation of immature neurons. Neuroscience (2008) 1.06
Quantitative studies of the antagonism of morphine by nalorphine and naloxone. J Pharmacol Exp Ther (1969) 1.04
A proteomic approach to receptor signaling: molecular mechanisms and therapeutic implications derived from discovery of the dopamine D2 receptor signalplex. Eur J Pharmacol (2007) 1.02
Internalization of mu-opioid receptors produced by etorphine in the rat locus coeruleus. Neuroscience (2001) 1.02
Endogenous opioids regulate dendritic growth and spine formation in developing rat brain. Brain Res (1987) 1.01
Lack of reward and locomotor stimulation induced by heroin in mu-opioid receptor-deficient mice. Eur J Pharmacol (2002) 1.00
Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS). Biochem Pharmacol (2005) 0.98
Analysis of membrane protein complexes using the split-ubiquitin membrane yeast two-hybrid (MYTH) system. Methods Mol Biol (2009) 0.96
Neurotrophin-regulated sorting of opioid receptors in the biosynthetic pathway of neurosecretory cells. J Neurosci (2003) 0.95
In vivo trafficking of endogenous opioid receptors. Life Sci (2008) 0.91
Opioid receptors and their interacting proteins. Neuromolecular Med (2005) 0.91
A study of oral morphine preference in inbred mouse strains. Psychiatr Genet (1994) 0.89
The long and the short of Wnt signaling in C. elegans. Curr Opin Genet Dev (2008) 0.89
Chronic morphine exposure alters the dendritic morphology of pyramidal neurons in visual cortex of rats. Neurosci Lett (2007) 0.87
The effects of repeated morphine exposure on mu opioid receptor number and affinity in C57BL/6J and DBA/2J mice. Life Sci (1997) 0.86
Optimized expression and purification of myristoylated human neuronal calcium sensor 1 in E. coli. Protein Expr Purif (2008) 0.79
Interactions between G-protein-coupled receptors and periplakin: a selective means to regulate G-protein activation. Biochem Soc Trans (2004) 0.79
Chronic fentanyl treatments induce the up-regulation of mu opioid receptor mRNA in rat pheochromocytoma cells. Brain Res (2000) 0.78
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology (2003) 3.66
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
National Institutes of Health State-of-the-Science Conference statement: preventing alzheimer disease and cognitive decline. Ann Intern Med (2010) 3.24
Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes (2007) 2.59
Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. Am J Hum Genet (2003) 2.55
NIH state-of-the-science conference statement: Preventing Alzheimer's disease and cognitive decline. NIH Consens State Sci Statements (2010) 2.19
Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive. Nature (2012) 2.19
Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Mol Cell Biol (2008) 2.05
Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae. Nature (2012) 2.05
Large-scale identification of yeast integral membrane protein interactions. Proc Natl Acad Sci U S A (2005) 2.03
Acetylcholine receptor (AChR) α5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (α4β2)₂α5 AChR function. Mol Pharmacol (2010) 2.02
Role of functional genetic variation in the dopamine D2 receptor (DRD2) in response to bupropion and nicotine replacement therapy for tobacco dependence: results of two randomized clinical trials. Neuropsychopharmacology (2006) 1.93
A global analysis of genetic interactions in Caenorhabditis elegans. J Biol (2007) 1.78
Pharmacogenetic approaches to the treatment of alcohol addiction. Nat Rev Neurosci (2011) 1.74
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6. Sci Signal (2009) 1.54
Up-regulation of neuronal calcium sensor-1 (NCS-1) in the prefrontal cortex of schizophrenic and bipolar patients. Proc Natl Acad Sci U S A (2002) 1.51
Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress. Environ Health Perspect (2010) 1.47
Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor. J Neurosci (2002) 1.44
Greater than age-related changes in brain diffusion of HIV patients after 1 year. J Neuroimmune Pharmacol (2008) 1.44
Elucidating the role of genetic factors in smoking behavior and nicotine dependence. Am J Med Genet B Neuropsychiatr Genet (2003) 1.40
Utilizing the split-ubiquitin membrane yeast two-hybrid system to identify protein-protein interactions of integral membrane proteins. Sci STKE (2005) 1.39
The human Rothmund-Thomson syndrome gene product, RECQL4, localizes to distinct nuclear foci that coincide with proteins involved in the maintenance of genome stability. J Cell Sci (2005) 1.38
Stress-induced intracellular trafficking of corticotropin-releasing factor receptors in rat locus coeruleus neurons. Endocrinology (2007) 1.36
Region-directed phototransfection reveals the functional significance of a dendritically synthesized transcription factor. Nat Methods (2006) 1.34
ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily. Microbiol Mol Biol Rev (2009) 1.34
Glyceraldehyde 3-phosphate dehydrogenase serves as an accessory protein of the cardiac sarcolemmal K(ATP) channel. EMBO Rep (2005) 1.33
DAT genotype modulates brain and behavioral responses elicited by cigarette cues. Neuropsychopharmacology (2008) 1.31
Stress-induced redistribution of corticotropin-releasing factor receptor subtypes in the dorsal raphe nucleus. Biol Psychiatry (2009) 1.30
Detecting interactions with membrane proteins using a membrane two-hybrid assay in yeast. Nat Protoc (2010) 1.30
Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth. J Physiol (2006) 1.29
Agonist-induced internalization of corticotropin-releasing factor receptors in noradrenergic neurons of the rat locus coeruleus. Eur J Neurosci (2006) 1.28
Outbreak of cyclosporiasis associated with imported raspberries, Philadelphia, Pennsylvania, 2000. Emerg Infect Dis (2002) 1.26
Two-hybrid technologies in proteomics research. Curr Opin Biotechnol (2008) 1.26
Regulation of CD133 by HDAC6 promotes β-catenin signaling to suppress cancer cell differentiation. Cell Rep (2012) 1.24
Intra- and intermolecular interactions in sucrose transporters at the plasma membrane detected by the split-ubiquitin system and functional assays. Structure (2002) 1.24
Mapping protein-protein interactions for the yeast ABC transporter Ycf1p by integrated split-ubiquitin membrane yeast two-hybrid analysis. Mol Cell (2007) 1.22
Dopamine receptor-interacting proteins: the Ca(2+) connection in dopamine signaling. Trends Pharmacol Sci (2003) 1.21
Identification of novel ErbB3-interacting factors using the split-ubiquitin membrane yeast two-hybrid system. Genome Res (2003) 1.19
D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N. Mol Pharmacol (2002) 1.18
Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen. PLoS Genet (2008) 1.18
Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system. Mol Cell Proteomics (2008) 1.18
Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival. Exp Neurol (2002) 1.16
Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort. Addict Biol (2011) 1.16
Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity. Hum Mol Genet (2012) 1.15
Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics. Proc Natl Acad Sci U S A (2007) 1.15
Influence of overanxious disorder of childhood on the expression of anorexia nervosa. Int J Eat Disord (2008) 1.14
Collateralized dorsal raphe nucleus projections: a mechanism for the integration of diverse functions during stress. J Chem Neuroanat (2011) 1.14
The multiple-specificity landscape of modular peptide recognition domains. Mol Syst Biol (2011) 1.14
Genomic landscape of a three-generation pedigree segregating affective disorder. PLoS One (2009) 1.13
The genetics of anorexia nervosa collaborative study: methods and sample description. Int J Eat Disord (2008) 1.12
ADHD characteristics: I. Concurrent co-morbidity patterns in children & adolescents. Child Adolesc Psychiatry Ment Health (2008) 1.11
Cannabinoid receptors are localized to noradrenergic axon terminals in the rat frontal cortex. Brain Res (2006) 1.10
Hypothalamic projections to locus coeruleus neurons in rat brain. Eur J Neurosci (2005) 1.10
Dominant and recessive distal renal tubular acidosis mutations of kidney anion exchanger 1 induce distinct trafficking defects in MDCK cells. Traffic (2006) 1.10
The split-ubiquitin membrane-based yeast two-hybrid system. Methods Mol Biol (2004) 1.09
Yeast-based functional genomics and proteomics technologies: the first 15 years and beyond. Biotechniques (2006) 1.09
Presynaptic inhibition of diverse afferents to the locus ceruleus by kappa-opiate receptors: a novel mechanism for regulating the central norepinephrine system. J Neurosci (2008) 1.08
The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase. Oncogene (2004) 1.08
The Rho1 GTPase acts together with a vacuolar glutathione S-conjugate transporter to protect yeast cells from oxidative stress. Genetics (2011) 1.08
Yeast as a tool to study bacterial effectors. Curr Opin Microbiol (2009) 1.08
Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors. Brain Res (2009) 1.07
Impact of cannabis use during stabilization on methadone maintenance treatment. Am J Addict (2013) 1.06
The post-genomic era of interactive proteomics: facts and perspectives. Proteomics (2002) 1.06
Application of the split-ubiquitin membrane yeast two-hybrid system to investigate membrane protein interactions. Methods (2004) 1.06
Differential projections of dorsal raphe nucleus neurons to the lateral septum and striatum. J Chem Neuroanat (2006) 1.05
Ultrastructural evidence for a role of gamma-aminobutyric acid in mediating the effects of corticotropin-releasing factor on the rat dorsal raphe serotonin system. J Comp Neurol (2005) 1.04
Using the yeast two-hybrid system to identify interacting proteins. Methods Mol Biol (2004) 1.04
Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio. Dev Biol (2004) 1.03
The Bloom's syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6. Biol Chem (2003) 1.03
HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress. J Neuropathol Exp Neurol (2010) 1.03
A proteomic approach to receptor signaling: molecular mechanisms and therapeutic implications derived from discovery of the dopamine D2 receptor signalplex. Eur J Pharmacol (2007) 1.02
A high-risk study of bipolar disorder. Childhood clinical phenotypes as precursors of major mood disorders. Arch Gen Psychiatry (2011) 1.02
Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid. Toxicol Appl Pharmacol (2007) 1.02
Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1. Mol Cell Biol (2004) 1.01
p300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization. J Cell Sci (2009) 1.01
HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol Dis (2011) 1.01
Ptena and ptenb genes play distinct roles in zebrafish embryogenesis. Dev Dyn (2005) 1.00
Evolution and expression of D2 and D3 dopamine receptor genes in zebrafish. Dev Dyn (2004) 1.00
Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates. Brain Res (2009) 0.99
KDP-1 is a nuclear envelope KASH protein required for cell-cycle progression. J Cell Sci (2009) 0.99
Coordination of N-glycosylation and protein translocation across the endoplasmic reticulum membrane by Sss1 protein. J Biol Chem (2003) 0.99
Tracking emotional valence: the role of the orbitofrontal cortex. Hum Brain Mapp (2011) 0.99
Endothelial cell loss and surgically induced astigmatism after sutureless large-incision manual cataract extraction (SLIMCE). Arch Ophthalmol (2009) 0.99