Published in Methods on June 27, 2008
Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells. Chem Rev (2011) 1.88
Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition. PLoS Genet (2016) 1.44
HIV-1 Nef dimerization is required for Nef-mediated receptor downregulation and viral replication. J Mol Biol (2009) 1.19
Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system. Microbiol Mol Biol Rev (2012) 1.11
Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3. PLoS One (2012) 1.08
α-Catulin CTN-1 is required for BK channel subcellular localization in C. elegans body-wall muscle cells. EMBO J (2010) 0.97
Mechanisms of tumor resistance to EGFR-targeted therapies. Expert Opin Ther Targets (2009) 0.96
A novel auxiliary subunit critical to BK channel function in Caenorhabditis elegans. J Neurosci (2010) 0.91
Live-cell imaging in Caenorhabditis elegans reveals the distinct roles of dynamin self-assembly and guanosine triphosphate hydrolysis in the removal of apoptotic cells. Mol Biol Cell (2009) 0.87
Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation. Mol Biol Cell (2009) 0.87
WAVE forms hetero- and homo-oligomeric complexes at integrin junctions in Drosophila visualized by bimolecular fluorescence complementation. J Biol Chem (2010) 0.87
Detection of protein interactions in plant using a gateway compatible bimolecular fluorescence complementation (BiFC) system. J Vis Exp (2011) 0.80
The Caenorhabditis elegans T-box factor MLS-1 requires Groucho co-repressor interaction for uterine muscle specification. PLoS Genet (2011) 0.78
Characterization of the latent membrane protein 1 signaling complex of Epstein-Barr virus in the membrane of mammalian cells with bimolecular fluorescence complementation. Virol J (2011) 0.78
Overcoming uncertainty through advances in fluorescence imaging of molecular processes in cells. Methods (2008) 0.75
Mitochondrial chaperone HSP-60 regulates anti-bacterial immunity via p38 MAP kinase signaling. EMBO J (2017) 0.75
Regulation of WNT Signaling at the Neuromuscular Junction by the Immunoglobulin Super-Family Protein RIG-3 in Caenorhabditis elegans. Genetics (2017) 0.75
A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat Biotechnol (2002) 22.05
Protein interaction mapping in C. elegans using proteins involved in vulval development. Science (2000) 11.61
Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol Cell (2002) 10.81
Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics (2001) 10.29
DNA transformation. Methods Cell Biol (1995) 9.27
Protein prenylation: molecular mechanisms and functional consequences. Annu Rev Biochem (1996) 8.08
Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol (2006) 5.91
Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis. Nat Biotechnol (2003) 5.01
Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4. Science (2002) 4.33
Genome-wide prediction of C. elegans genetic interactions. Science (2006) 4.15
Visualization of molecular interactions by fluorescence complementation. Nat Rev Mol Cell Biol (2006) 3.79
Combined functional genomic maps of the C. elegans DNA damage response. Science (2002) 3.74
Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells. Nat Protoc (2006) 3.22
Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions. Biotechniques (2006) 2.99
Temporal and spatial expression patterns of the small heat shock (hsp16) genes in transgenic Caenorhabditis elegans. Mol Biol Cell (1992) 2.98
Using GFP in FRET-based applications. Trends Cell Biol (1999) 2.55
Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Curr Biol (2002) 2.47
Universal strategies in research and drug discovery based on protein-fragment complementation assays. Nat Rev Drug Discov (2007) 2.20
UNC-1 regulates gap junctions important to locomotion in C. elegans. Curr Biol (2007) 1.91
An improved mRFP1 adds red to bimolecular fluorescence complementation. Nat Methods (2006) 1.57
Detection of protein-protein interactions by protein fragment complementation strategies. Methods Enzymol (2000) 1.51
Detecting protein-protein interactions with GFP-fragment reassembly. Nat Methods (2004) 1.45
Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus. Development (2007) 1.37
Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein. Cytometry (2001) 1.28
Stop making nonSense: the C. elegans smg genes. Trends Genet (2001) 1.26
Visualization of protein interactions in living Caenorhabditis elegans using bimolecular fluorescence complementation analysis. Nat Protoc (2008) 1.20
Visualizing protein interactions in living cells using digitized GFP imaging and FRET microscopy. Methods Cell Biol (1999) 1.04
Fluorescence resonance energy transfer analysis of protein-protein interactions in single living cells by multifocal multiphoton microscopy. J Biotechnol (2002) 1.03
Building a protein interaction map: research in the post-genome era. Bioessays (2000) 0.82
Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions. Biotechniques (2006) 2.99
Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. J Biol Chem (2012) 1.79
Visualization of AP-1 NF-kappaB ternary complexes in living cells by using a BiFC-based FRET. Proc Natl Acad Sci U S A (2008) 1.55
An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio. Biotechniques (2010) 1.48
Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells. Mol Cell Biol (2004) 1.47
Label-free quantitative analysis of lipid metabolism in living Caenorhabditis elegans. J Lipid Res (2009) 1.41
Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization. EMBO J (2006) 1.41
Ionizing radiation induces prostate cancer neuroendocrine differentiation through interplay of CREB and ATF2: implications for disease progression. Cancer Res (2008) 1.33
Bimolecular fluorescence complementation (BiFC): a 5-year update and future perspectives. Biotechniques (2012) 1.32
Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis. Mol Cell Biol (2009) 1.24
Regulation of nucleocytoplasmic trafficking of transcription factor OREBP/TonEBP/NFAT5. J Biol Chem (2006) 1.24
Fluorescence complementation: an emerging tool for biological research. Trends Biotechnol (2008) 1.23
TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src. J Cell Sci (2006) 1.21
Visualization of protein interactions in living Caenorhabditis elegans using bimolecular fluorescence complementation analysis. Nat Protoc (2008) 1.20
Visualization of ternary complexes in living cells by using a BiFC-based FRET assay. Nat Protoc (2008) 1.11
Ligand-dependent oligomerization of dopamine D(2) and adenosine A(2A) receptors in living neuronal cells. Mol Pharmacol (2008) 1.02
Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis. Mol Cell Biol (2009) 1.00
Comprehensive characterization of interaction complexes of herpes simplex virus type 1 ICP22, UL3, UL4, and UL20.5. J Virol (2010) 0.97
Ionizing radiation induces neuroendocrine differentiation of prostate cancer cells in vitro, in vivo and in prostate cancer patients. Am J Cancer Res (2011) 0.95
Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation. Mol Biol Cell (2009) 0.87
Transcriptional activity of c-Jun is critical for the suppression of AR function. Mol Cell Endocrinol (2013) 0.84
Bimolecular fluorescence complementation (BiFC) analysis of protein-protein interaction: how to calculate signal-to-noise ratio. Methods Cell Biol (2013) 0.82
Critical role of N-terminal end-localized nuclear export signal in regulation of activating transcription factor 2 (ATF2) subcellular localization and transcriptional activity. J Biol Chem (2012) 0.82
Bimolecular fluorescence complementation analysis of G protein-coupled receptor dimerization in living cells. Methods Enzymol (2013) 0.76