HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

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Published in Oncogene on June 30, 2008

Authors

H Korkaya1, A Paulson, F Iovino, M S Wicha

Author Affiliations

1: Department of Internal Medicine, Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA. hkorkaya@med.umich.edu

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Regulation of rat mammary gene expression by extracellular matrix components. Exp Cell Res (1987) 1.75

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Unsaturated fatty acid requirements for growth and survival of a rat mammary tumor cell line. Cancer Res (1978) 0.93

cDNA cloning and molecular characterization of MSE55, a novel human serum constituent protein that displays bone marrow stromal/endothelial cell-specific expression. J Biol Chem (1992) 0.93

Extracellular matrix and the hematopoietic microenvironment. J Lab Clin Med (1988) 0.92

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Macrophages express cell surface laminin. Exp Cell Res (1983) 0.91

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Genomic analysis of the 67-kDa laminin receptor in normal and pathological tissues: circumstantial evidence for retroposon features. Genomics (1991) 0.81

Production of mammastatin, a tissue-specific growth inhibitor, by normal human mammary cells. Science (1989) 0.81

Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer Res (1981) 0.80

Inhibition of protein synthesis by didemnin B is not sufficient to induce apoptosis in human mammary carcinoma (MCF7) cells. Biochem Pharmacol (1999) 0.80

A potential role for the extracellular matrix glycoprotein laminin in macrophage-tumor-cell interactions. Int J Cancer (1985) 0.80

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Immunolymphoscintigraphy in breast cancer: evaluation using 131I-labeled monoclonal antibody B72.3. Nucl Med Biol (1998) 0.78

[Blood coagulation changes in patients with post-splenectomy persistent thrombocytosis]. Chir Ital (2001) 0.78

Radioimmunoguided surgery in colorectal cancer: a 6-year experience with four different technical solutions. Semin Surg Oncol (1998) 0.78

Developmental regulation of granulocytic cell binding to hemonectin. Blood (1990) 0.77

Respiration and gene expression in germinating ascospores of Neurospora tetrasperma. FEMS Microbiol Lett (1992) 0.77

Blocking basement membrane collagen deposition inhibits the growth of 7,12-dimethylbenzanthracene-induced rat mammary tumors. Cancer Lett (1981) 0.77

Fibrin glue to reduce seroma after axillary lymphadenectomy for breast cancer. Minerva Chir (2008) 0.77

A bcl-xS adenovirus selectively induces apoptosis in transformed cells compared to normal mammary cells. Neoplasia (2000) 0.77

Heat shock gene expression in germinating ascospores of Neurospora tetrasperma. FEMS Microbiol Lett (1992) 0.77

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Swedish nurses' estimation of fatigue as a symptom in cancer patients--report of a questionnaire. Eur J Cancer Care (Engl) (1997) 0.77

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A method of limited replication for the efficient in vivo delivery of adenovirus to cancer cells. Hum Gene Ther (1998) 0.75

Histochemical detection of gamma aminobutyric acid (GABA) degradative enzymes in the Purkinje cell population of old rat cerebellum. Basic Appl Histochem (1979) 0.75

[Rectal prolapse]. J Chir (Paris) (2000) 0.75

Collagen-production inhibitors evaluated as antitumor agents. J Natl Cancer Inst (1985) 0.75

[Axillary lymph node excision]. J Chir (Paris) (1998) 0.75

A bcl-x(S) adenovirus demonstrates therapeutic efficacy in an ascites model of human breast cancer. J Soc Gynecol Investig (2000) 0.75

Plurifocal breast cancer and double lymphatic spread. G Chir (2008) 0.75

Sentinel lymph node biopsy in the treatment of breast cancer. Experience in 527 cases. Minerva Chir (2007) 0.75

[Breast-conserving surgery in breast cancer]. G Chir (2006) 0.75

Lupus mastitis in systemic lupus erythematosus: a rare condition requiring a minimally invasive diagnostic approach. Int J Immunopathol Pharmacol (2012) 0.75

[Ductal carcinoma in situ of the breast]. G Chir (2006) 0.75

Distribution of pemphigus and pemphigoid antigens, laminin, and type IV collagen in corneal epithelium. Invest Ophthalmol Vis Sci (1981) 0.75

Kinetics of layer-thinning transitions in overheated smectic films. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics (2000) 0.75

[The integrated radiosurgical treatment of rectal cancer]. Ann Ital Chir (1999) 0.75