Published in Cell Stem Cell on July 03, 2008
Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature (2009) 4.32
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature (2010) 4.16
Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell (2013) 2.71
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell (2012) 1.96
Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development (2010) 1.81
Fgd5 identifies hematopoietic stem cells in the murine bone marrow. J Exp Med (2014) 1.62
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells. Blood (2009) 1.51
Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region. J Exp Med (2011) 1.48
Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells. Dev Cell (2016) 1.42
Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level. Nat Commun (2013) 1.35
ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes Dev (2011) 1.30
The expression of Sox17 identifies and regulates haemogenic endothelium. Nat Cell Biol (2013) 1.28
Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region. J Exp Med (2011) 1.25
Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells. Development (2010) 1.17
Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proc Natl Acad Sci U S A (2012) 1.14
Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis. Cell Stem Cell (2012) 1.11
Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. J Exp Med (2015) 1.07
Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs. Blood (2013) 1.07
Tracing the origin of the HSC hierarchy reveals an SCF-dependent, IL-3-independent CD43(-) embryonic precursor. Stem Cell Reports (2014) 1.06
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells. Development (2013) 1.05
A short history of hemogenic endothelium. Blood Cells Mol Dis (2013) 1.05
Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development. Development (2009) 1.04
Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood (2011) 1.04
Tracing haematopoietic stem cell formation at single-cell resolution. Nature (2016) 1.03
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo. J Exp Med (2013) 0.99
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells. J Clin Invest (2015) 0.97
Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development. Stem Cell Reports (2014) 0.94
Progressive maturation toward hematopoietic stem cells in the mouse embryo aorta. Blood (2014) 0.92
Effect of developmental stage of HSC and recipient on transplant outcomes. Dev Cell (2014) 0.91
GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1. Nat Cell Biol (2015) 0.91
Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters. Mol Cell Biol (2014) 0.90
Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood (2015) 0.88
Identification of the niche and phenotype of the first human hematopoietic stem cells. Stem Cell Reports (2014) 0.87
Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver. Development (2016) 0.87
The Notch ligand DLL4 specifically marks human hematoendothelial progenitors and regulates their hematopoietic fate. Leukemia (2015) 0.86
Interleukin-3 promotes hemangioblast development in mouse aorta-gonad-mesonephros region. Haematologica (2009) 0.85
Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis. PLoS One (2012) 0.85
Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this. Development (2014) 0.84
Specification and function of hemogenic endothelium during embryogenesis. Cell Mol Life Sci (2016) 0.83
An expandable, inducible hemangioblast state regulated by fibroblast growth factor. Stem Cell Reports (2014) 0.83
Placenta as a newly identified source of hematopoietic stem cells. Curr Opin Hematol (2010) 0.82
Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4. Stem Cells Dev (2010) 0.81
Making Blood: The Haematopoietic Niche throughout Ontogeny. Stem Cells Int (2015) 0.80
A view of human haematopoietic development from the Petri dish. Nat Rev Mol Cell Biol (2016) 0.80
Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells. Nat Commun (2016) 0.79
Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence. PLoS One (2016) 0.79
Leucine-rich repeat-containing G-protein-coupled Receptor 5 marks short-term hematopoietic stem and progenitor cells during mouse embryonic development. J Biol Chem (2014) 0.79
Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence. J Exp Med (2014) 0.78
Common developmental pathway for primitive erythrocytes and multipotent hematopoietic progenitors in early mouse development. Stem Cell Reports (2013) 0.77
Murine hemogenic endothelial precursors display heterogeneous hematopoietic potential ex vivo. Exp Hematol (2017) 0.76
A long way to stemness. Cell Cycle (2012) 0.76
The Hemogenic Competence of Endothelial Progenitors Is Restricted by Runx1 Silencing during Embryonic Development. Cell Rep (2016) 0.76
Development of hematopoietic stem and progenitor cells from human pluripotent stem cells. J Cell Biochem (2015) 0.76
BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo. Stem Cell Reports (2016) 0.76
Return to youth with Sox17. Genes Dev (2011) 0.76
The origins of blood: induction of hematopoietic stem cells from different sources. Cell Stem Cell (2008) 0.76
Rat embryonic mast cells originate in the AGM. PLoS One (2013) 0.75
The molecular basis of endothelial cell plasticity. Nat Commun (2017) 0.75
The many faces of hematopoietic stem cell heterogeneity. Development (2016) 0.75
Developing HSCs become Notch independent by the end of maturation in the AGM region. Blood (2016) 0.75
Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation. Blood (2016) 0.75
Restricted intra-embryonic origin of bona fide hematopoietic stem cells in the chicken. Development (2017) 0.75
Cell cycle dynamics and complement expression distinguishes mature hematopoietic subsets arising from hemogenic endothelium. Cell Cycle (2017) 0.75
Control of mammary stem cell function by steroid hormone signalling. Nature (2010) 5.38
Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat Cell Biol (2010) 3.61
Effectiveness of anticholinergic drugs compared with placebo in the treatment of overactive bladder: systematic review. BMJ (2003) 2.29
Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells. Nature (2010) 1.94
Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta. Proc Natl Acad Sci U S A (2007) 1.93
Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3. J Cell Biol (2010) 1.72
Duloxetine compared with placebo for treating women with symptoms of overactive bladder. BJU Int (2007) 1.70
Progressive divergence of definitive haematopoietic stem cells from the endothelial compartment does not depend on contact with the foetal liver. Development (2005) 1.64
Identification and characterization of thymic epithelial progenitor cells. Immunity (2002) 1.53
Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region. J Exp Med (2011) 1.48
Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet (2011) 1.38
Functional evidence for a single endodermal origin for the thymic epithelium. Nat Immunol (2004) 1.36
Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2. Cell Rep (2013) 1.33
Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region. J Exp Med (2011) 1.25
Regeneration of the aged thymus by a single transcription factor. Development (2014) 1.23
Endocrine therapy resistance can be associated with high estrogen receptor alpha (ERalpha) expression and reduced ERalpha phosphorylation in breast cancer models. Endocr Relat Cancer (2006) 1.21
Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods. J Mammary Gland Biol Neoplasia (2012) 1.17
Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells. Proc Natl Acad Sci U S A (2008) 1.13
Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis. Cell Stem Cell (2012) 1.11
Restoration of Runx1 expression in the Tie2 cell compartment rescues definitive hematopoietic stem cells and extends life of Runx1 knockout animals until birth. Stem Cells (2009) 1.10
Water quality monitoring: a combined approach to investigate gradients of change in the Great Barrier Reef, Australia. Mar Pollut Bull (2005) 1.08
Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs. Blood (2013) 1.07
Stem cells: Fusion brings down barriers. Nature (2003) 1.05
The essential requirement for Runx1 in the development of the sternum. Dev Biol (2010) 1.02
Role of host cell traversal by the malaria sporozoite during liver infection. J Exp Med (2013) 1.01
EVA regulates thymic stromal organisation and early thymocyte development. Biochem Biophys Res Commun (2007) 0.99
Drug pricing and value in oncology. Oncologist (2010) 0.99
Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X. Mamm Genome (2006) 0.99
Bmp4 and Noggin expression during early thymus and parathyroid organogenesis. Gene Expr Patterns (2006) 0.99
A critical role for lipophosphoglycan in proinflammatory responses of dendritic cells to Leishmania mexicana. Eur J Immunol (2005) 0.98
Alternative Runx1 promoter usage in mouse developmental hematopoiesis. Blood Cells Mol Dis (2009) 0.97
A developmental look at thymus organogenesis: where do the non-hematopoietic cells in the thymus come from? Curr Opin Immunol (2003) 0.94
Dynamics of thymus organogenesis and colonization in early human development. Development (2013) 0.94
Regulation of boundary cap neural crest stem cell differentiation after transplantation. Stem Cells (2009) 0.94
A novel method for the generation of reaggregated organotypic cultures that permits juxtaposition of defined cell populations. Genesis (2009) 0.94
Labeling of hematopoietic stem and progenitor cells in novel activatable EGFP reporter mice. Genesis (2003) 0.89
Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. PLoS Genet (2010) 0.89
Hematopoietic stem cell activity in the aorta-gonad-mesonephros region enhances after mid-day 11 of mouse development. Int J Dev Biol (2010) 0.88
Suppression of interneuron programs and maintenance of selected spinal motor neuron fates by the transcription factor AML1/Runx1. Proc Natl Acad Sci U S A (2008) 0.88
The discovery of a source of adult hematopoietic cells in the embryo. Development (2008) 0.88
Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration. Invest Ophthalmol Vis Sci (2013) 0.88
New serum-free in vitro culture technique for midgestation mouse embryos. Genesis (2003) 0.87
Hoxb4-YFP reporter mouse model: a novel tool for tracking HSC development and studying the role of Hoxb4 in hematopoiesis. Blood (2011) 0.87
Multifunctional reversible knockout/reporter system enabling fully functional reconstitution of the AML1/Runx1 locus and rescue of hematopoiesis. Genesis (2006) 0.87
EphB-ephrin-B2 interactions are required for thymus migration during organogenesis. Proc Natl Acad Sci U S A (2010) 0.86
Depression among older people with cognitive impairment: prevalence and detection. Int J Geriatr Psychiatry (2006) 0.85
Transgenic tools for analysis of the haematopoietic system: knock-in CD45 reporter and deletor mice. J Immunol Methods (2008) 0.84
Intraoperative sonography of intracranial arteriovenous malformations: how we do it. J Ultrasound Med (2004) 0.83
Rapid constitutive generation of a specific peptide-MHC class II complex from intact exogenous protein in immature murine dendritic cells. Eur J Immunol (2002) 0.81
The differentiation program of embryonic definitive hematopoietic stem cells is largely alpha4 integrin independent. Blood (2006) 0.81
Thymus organogenesis and development of the thymic stroma. Methods Mol Biol (2007) 0.80
Imaging sporozoite cell traversal in the liver of mice. Methods Mol Biol (2013) 0.80
Uncompromised generation of a specific H-2DM-dependent peptide-MHC class II complex from exogenous antigen in Leishmania mexicana-infected dendritic cells. Eur J Immunol (2003) 0.79
Postmenstrual gestational age should be used with care in studies of early human hematopoietic development. Blood (2013) 0.78
Incentives, Program Configuration, and Employee Uptake of Workplace Wellness Programs. J Occup Environ Med (2016) 0.78
Serum-free culture of mid-gestation mouse embryos: a tool for the study of endoderm-derived organs. Methods Mol Biol (2014) 0.78
In vivo and in vitro assays of thymic organogenesis. Methods Mol Med (2005) 0.77
Restraint and self-injury in people with intellectual disabilities: a review. J Intellect Disabil (2007) 0.77
Endothelio-hematopoietic relationship: getting closer to the beginnings. BMC Biol (2011) 0.77
Variable effects of the mitoK(ATP) channel modulators diazoxide and 5-HD in ATP-depleted renal epithelial cells. Mol Cell Biochem (2009) 0.77
Generation of tissue organoids by compaction reaggregation. Methods Mol Biol (2014) 0.75
Abstract 47: surgical treatment of nipple malposition in nipple sparing mastectomy device-based reconstruction. Plast Reconstr Surg (2014) 0.75
Developmental hematopoiesis - preface. Int J Dev Biol (2010) 0.75
An antibody raised against in vitro-derived human mast cells identifies mature mast cells and a population of cells that are Fc epsilon RI(+), tryptase(-), and chymase(-) in a variety of human tissues. J Histochem Cytochem (2003) 0.75