Published in Biotechnol Bioeng on April 20, 1997
A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: cloning, overexpression and properties. Extremophiles (2005) 1.27
The effect of the local delivery of platelet-derived growth factor from reactive two-component polyurethane scaffolds on the healing in rat skin excisional wounds. Biomaterials (2009) 1.18
Deactivation of the sporulation transcription factor Spo0A by the Spo0E protein phosphatase. Proc Natl Acad Sci U S A (1994) 2.24
Purification and properties of the phosphotriesterase from Pseudomonas diminuta. J Biol Chem (1989) 2.03
Identification of a plasmid-borne parathion hydrolase gene from Flavobacterium sp. by southern hybridization with opd from Pseudomonas diminuta. Appl Environ Microbiol (1986) 1.93
Theatre over-shoes do not reduce operating theatre floor bacterial counts. J Hosp Infect (1991) 1.92
The organization and regulation of the pyrBI operon in E. coli includes a rho-independent attenuator sequence. Mol Gen Genet (1982) 1.85
Coherence between low-frequency activation of the motor cortex and tremor in patients with essential tremor. Lancet (2000) 1.72
Rational modification of enzyme catalysis by engineering surface charge. Nature (1987) 1.71
Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry (2008) 1.67
Linear one-step assay for the determination of orthophosphate. Anal Biochem (1983) 1.64
Effects of mechanical signaling on plant cell cytosolic calcium. Proc Natl Acad Sci U S A (1995) 1.63
Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs. Oncogene (1998) 1.56
Nucleotide sequence of the structural gene (pyrB) that encodes the catalytic polypeptide of aspartate transcarbamoylase of Escherichia coli. Proc Natl Acad Sci U S A (1983) 1.44
Phosphorylation of Spo0A activates its stimulation of in vitro transcription from the Bacillus subtilis spoIIG operon. Mol Microbiol (1993) 1.44
Prediction of electrostatic effects of engineering of protein charges. Nature (1987) 1.44
The DNA sequence of argI from Escherichia coli K12. Nucleic Acids Res (1983) 1.32
Cloning and sequencing of a plasmid-borne gene (opd) encoding a phosphotriesterase. J Bacteriol (1988) 1.29
A hysterographic study of the abdominal hysterotomy scar. J Obstet Gynaecol Br Commonw (1969) 1.26
Guidelines for dyspepsia management in general practice using focus groups. Br J Gen Pract (1997) 1.23
Electrostatic effects on modification of charged groups in the active site cleft of subtilisin by protein engineering. J Mol Biol (1987) 1.20
Inactivation of organophosphorus nerve agents by the phosphotriesterase from Pseudomonas diminuta. Arch Biochem Biophys (1990) 1.18
Organophosphorus hydrolase is a remarkably stable enzyme that unfolds through a homodimeric intermediate. Biochemistry (1997) 1.16
Dissimilar plasmids isolated from Pseudomonas diminuta MG and a Flavobacterium sp. (ATCC 27551) contain identical opd genes. Appl Environ Microbiol (1988) 1.15
Nerve agents degraded by enzymatic foams. Nature (1998) 1.14
Mechanism and stereochemical course at phosphorus of the reaction catalyzed by a bacterial phosphotriesterase. Biochemistry (1988) 1.14
Digoxin pharmacokinetics: multicompartmental analysis and its clinical implications. Br J Clin Pharmacol (1976) 1.07
The Bacillus subtilis response regulator Spo0A stimulates transcription of the spoIIG operon through modification of RNA polymerase promoter complexes. J Mol Biol (1996) 1.05
Reconstruction of an enzyme by domain substitution effectively switches substrate specificity. Nature (1989) 1.04
Protein differentiation: a comparison of aspartate transcarbamoylase and ornithine transcarbamoylase from Escherichia coli K-12. Proc Natl Acad Sci U S A (1984) 1.03
The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well. Br J Pharmacol (2009) 1.03
Structure and mechanism of arylamine N-acetyltransferases. Curr Top Med Chem (2006) 1.03
Characterization of P-S bond hydrolysis in organophosphorothioate pesticides by organophosphorus hydrolase. Arch Biochem Biophys (1995) 1.02
The effect of surgical theatre head-gear on air bacterial counts. J Hosp Infect (1991) 1.00
Expression of Pseudomonas phosphotriesterase activity in the fall armyworm confers resistance to insecticides. Experientia (1990) 0.99
Light-induced tailoring of PEG-hydrogel properties. Biomaterials (1998) 0.98
Creating molecular barriers to acute platelet deposition on damaged arteries with reactive polyethylene glycol. J Biomed Mater Res (1998) 0.96
Bimetallic binding motifs in organophosphorus hydrolase are important for catalysis and structural organization. J Biol Chem (1994) 0.96
Regulatory divergence of aspartate transcarbamoylases within the enterobacteriaceae. Arch Biochem Biophys (1980) 0.95
Rational design of organophosphorus hydrolase for altered substrate specificities. Chem Biol Interact (1999) 0.95
Molecular barriers to biomaterial thrombosis by modification of surface proteins with polyethylene glycol. Biomaterials (1998) 0.92
New assay for enzymatic phosphate release: application to aspartate transcarbamylase and other enzymes. Anal Biochem (1983) 0.92
In vivo formation of hybrid aspartate transcarbamoylases from native subunits of divergent members of the family Enterobacteriaceae. J Bacteriol (1986) 0.92
Role of diffusion in nonaqueous enzymology. 1. Theory. Enzyme Microb Technol (1992) 0.91
Comparison of the aspartate transcarbamoylases from Serratia marcescens and Escherichia coli. J Biol Chem (1989) 0.91
Characterization of organophosphorus hydrolases and the genetic manipulation of the phosphotriesterase from Pseudomonas diminuta. Chem Biol Interact (1993) 0.90
Treatment of rat pancreatic islets with reactive PEG. Biomaterials (2000) 0.90
The role of hydration in enzyme activity and stability: 2. Alcohol dehydrogenase activity and stability in a continuous gas phase reactor. Biotechnol Bioeng (1996) 0.90
Assembly of the aspartate transcarbamoylase holoenzyme from transcriptionally independent catalytic and regulatory cistrons. J Bacteriol (1984) 0.90
A mutation in the catalytic cistron of aspartate carbamoyltransferase affecting catalysis, regulatory response and holoenzyme assembly. Nature (1981) 0.89
Properties of hybrid aspartate transcarbamoylase formed with native subunits from divergent bacteria. J Biol Chem (1984) 0.89
Effect of helium gas at elevated pressure on iron transport and growth of Escherichia coli. J Bacteriol (1974) 0.89
Unique aspects of the regulation of the aspartate transcarbamylase of Serratia marcescens. J Bacteriol (1976) 0.88
Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities. Protein Eng Des Sel (2008) 0.88
Poly(ethylene glycol) hydrogel-encapsulated fluorophore-enzyme conjugates for direct detection of organophosphorus neurotoxins. Anal Chem (1999) 0.88
Discrimination between nucleotide effector responses of aspartate transcarbamoylase due to a single site substitution in the allosteric binding site. J Biol Chem (1989) 0.88
No evidence of the inactivating mutation (C566T) in the follicle-stimulating hormone receptor gene in Brazilian women with premature ovarian failure. Fertil Steril (1998) 0.87
Hydrolysis of tetriso by an enzyme derived from Pseudomonas diminuta as a model for the detoxication of O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothiolate (VX). Biochem Pharmacol (1995) 0.86
Efficient total gene synthesis of 1.35-kb hybrid alpha-lytic protease gene using the polymerase chain reaction. PCR Methods Appl (1993) 0.86
The development of a new biosensor based on recombinant E. coli for the direct detection of organophosphorus neurotoxins. Biosens Bioelectron (1996) 0.85
A novel missense mutation (S18N) in the 5' non-HMG box region of the SRY gene in a patient with partial gonadal dysgenesis and his normal male relatives. Hum Genet (1998) 0.85
Modification of near active site residues in organophosphorus hydrolase reduces metal stoichiometry and alters substrate specificity. Biochemistry (1999) 0.84
Detection of organophosphorus pesticide detoxifying bacterial colonies, using UV-photography of parathion-impregnated filters. Arch Environ Contam Toxicol (1988) 0.84
Enzymatic hydrolysis of Russian-VX by organophosphorus hydrolase. Biochem Biophys Res Commun (1997) 0.84
IQ in childhood psychiatric attendees predicts outcome of later schizophrenia at 21 year follow-up. Acta Psychiatr Scand (2002) 0.84
Temperature effects on the allosteric responses of native and chimeric aspartate transcarbamoylases. J Mol Biol (1998) 0.84
Peritoneal cystic mesothelioma: an electron microscopic and immunohistochemical study of two male patients. J Clin Pathol (1986) 0.83
Biotransformation patterns of 2,4,6-trinitrotoluene by aerobic bacteria. Curr Microbiol (1998) 0.83
Analysis of structure-function relationships by formation of chimeric enzymes produced by gene fusion. Methods Enzymol (1991) 0.83
Molecular evolution of enzyme structure: construction of a hybrid hamster/Escherichia coli aspartate transcarbamoylase. J Mol Evol (1989) 0.83
Site-specific substitutions of the Tyr-165 residue in the catalytic chain of aspartate transcarbamoylase promotes a T-state preference in the holoenzyme. J Biol Chem (1988) 0.83
Salmonella vascular graft infection. Lancet (1991) 0.82
Enzymatic catalysis of formation of Z-aspartame in ionic liquid - An alternative to enzymatic catalysis in organic solvents. Biotechnol Prog (2000) 0.82
Conversion of the allosteric regulatory patterns of aspartate transcarbamoylase by exchange of a single beta-strand between diverged regulatory chains. Biochemistry (1997) 0.82
Enzymatic dehalogenation of gas phase substrates with haloalkane dehalogenase. Biotechnol Bioeng (2000) 0.82
High pressure stabilization of acetylcholinesterase sizeozymes against thermal denaturation. Biophys Chem (1974) 0.81
Analysis of hydride transfer and cofactor fluorescence decay in mutants of dihydrofolate reductase: possible evidence for participation of enzyme molecular motions in catalysis. Biochemistry (1991) 0.81
Molecular barriers to biomaterial thrombosis by modification of surface proteins with polyethylene glycol. Biomaterials (1999) 0.81
Protein extraction and activity in reverse micelles of a nonionic detergent. Biotechnol Bioeng (1992) 0.80
Biocatalytic synthesis of fluorinated polyesters. Biotechnol Prog (2000) 0.79
Differential expression of CD32 isoforms following alloactivation of human T cells. Immunology (1997) 0.79
Genetic and biochemical characterization of distinct transport systems for uracil, uridine and cytidine in Salmonella typhimurium. Mol Gen Genet (1980) 0.79
An inpatient treatment model for adults with mild intellectual disability and challenging behaviour. J Intellect Disabil Res (1999) 0.79
Synthesis of protein-containing polymers in organic solvents. Biotechnol Bioeng (1995) 0.79
Encapsulation of phosphotriesterase within murine erythrocytes. Toxicol Appl Pharmacol (1994) 0.79
Are the Health of the Nation's targets attainable? Postal survey of general practitioner's views. BMJ (1997) 0.79
Determination of equilibrium and individual rate constants for subtilisin-catalyzed transesterification in anhydrous environments. Biotechnol Bioeng (1992) 0.79
Biocatalytic nerve agent detoxification in fire fighting foams. Biotechnol Bioeng (1999) 0.79
Thermoinactivation of diisopropylfluorophosphatase-containing polyurethane polymers. Biomacromolecules (2001) 0.78
Pyrimidine biosynthesis in Serratia marcescens: a possible role for nonsequential enzyme interactions in mimicking coordinate gene expression. Biochem Genet (1977) 0.78
Covalent binding of a nerve agent hydrolyzing enzyme within polyurethane foams. Biotechnol Bioeng (1996) 0.78
Pyrimidine biosynthesis in Serratia marcescens: polypeptide interactions of three nonsequential enzymes. Biochem Genet (1977) 0.78
Photoimmobilization of organophosphorus hydrolase within a PEG-based hydrogel. Biotechnol Bioeng (1999) 0.78
Sausage: protein threading with flexible force fields. Bioinformatics (1999) 0.78
Biocatalytic synthesis of acrylates in organic solvents and supercritical fluids: III. Does carbon dioxide covalently modify enzymes? Biotechnol Bioeng (1995) 0.78
Transmission electron microscopy of percutaneous fine needle aspirates from lung: a study of 70 cases. Thorax (1987) 0.78
Psychological treatment for obsessive-compulsive disorder in people with autism spectrum disorders--a pilot study. Psychother Psychosom (2008) 0.78