Predictors of patient-assessed illness severity in irritable bowel syndrome.

PubWeight™: 1.35‹?› | Rank: Top 10%

🔗 View Article (PMC 2949074)

Published in Am J Gastroenterol on June 12, 2008

Authors

Brennan Spiegel1, Amy Strickland, Bruce D Naliboff, Emeran A Mayer, Lin Chang

Author Affiliations

1: VA Greater Los Angeles Healthcare System, Center for Outcomes Research and Education, Los Angeles, California, USA.

Articles citing this

A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea. Gut (2013) 3.14

Functional GI disorders: from animal models to drug development. Gut (2007) 1.55

Patient-reported outcomes for irritable bowel syndrome are associated with patients' severity ratings of gastrointestinal symptoms and psychological factors. Clin Gastroenterol Hepatol (2011) 1.48

A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations. Behav Res Ther (2011) 1.18

Measuring irritable bowel syndrome patient-reported outcomes with an abdominal pain numeric rating scale. Aliment Pharmacol Ther (2009) 1.16

Challenges to the therapeutic pipeline for irritable bowel syndrome: end points and regulatory hurdles. Gastroenterology (2008) 1.14

Diagnosis and management of IBS. Nat Rev Gastroenterol Hepatol (2010) 1.14

Psychometric evaluation of patient-reported outcomes in irritable bowel syndrome randomized controlled trials: a Rome Foundation report. Gastroenterology (2009) 1.11

Gastrointestinal and psychological mediators of health-related quality of life in IBS and IBD: a structural equation modeling analysis. Am J Gastroenterol (2011) 1.09

Type, rather than number, of mental and physical comorbidities increases the severity of symptoms in patients with irritable bowel syndrome. Clin Gastroenterol Hepatol (2013) 1.06

The impact of abdominal pain on global measures in patients with chronic idiopathic constipation, before and after treatment with linaclotide: a pooled analysis of two randomised, double-blind, placebo-controlled, phase 3 trials. Aliment Pharmacol Ther (2014) 1.00

A focus group assessment of patient perspectives on irritable bowel syndrome and illness severity. Dig Dis Sci (2009) 0.96

Developing valid and reliable health utilities in irritable bowel syndrome: results from the IBS PROOF Cohort. Am J Gastroenterol (2009) 0.95

Understanding gastrointestinal distress: a framework for clinical practice. Am J Gastroenterol (2011) 0.92

Pathophysiology, evaluation, and treatment of bloating: hope, hype, or hot air? Gastroenterol Hepatol (N Y) (2011) 0.91

Subtypes and Symptomatology of Irritable Bowel Syndrome in Children and Adolescents: A School-based Survey Using Rome III Criteria. J Neurogastroenterol Motil (2012) 0.89

Characterizing abdominal pain in IBS: guidance for study inclusion criteria, outcome measurement and clinical practice. Aliment Pharmacol Ther (2010) 0.89

Association between symptoms of irritable bowel syndrome and methane and hydrogen on lactulose breath test. J Korean Med Sci (2013) 0.85

Lubiprostone: evaluation of the newest medication for the treatment of adult women with constipation-predominant irritable bowel syndrome. Int J Womens Health (2010) 0.85

Conditioned pain modulation in women with irritable bowel syndrome. Biol Res Nurs (2014) 0.83

Visceral sensitivity as a mediator of outcome in the treatment of irritable bowel syndrome. Behav Res Ther (2012) 0.81

Psychological therapies in patients with irritable bowel syndrome: a systematic review and meta-analysis of randomized controlled trials. Gastroenterol Res Pract (2015) 0.78

Fear of GI symptoms has an important impact on quality of life in patients with moderate-to-severe IBS. Am J Gastroenterol (2014) 0.78

Acute sodium bicarbonate loading has negligible effects on resting and exercise blood pressure but causes gastrointestinal distress. Nutr Res (2013) 0.77

Baroreflex mechanisms in Irritable Bowel Syndrome: Part I. Traditional indices. Physiol Behav (2016) 0.75

Clinical Dimensions of Bloating in Functional Gastrointestinal Disorders. J Neurogastroenterol Motil (2016) 0.75

Multidomain patient-reported outcomes of irritable bowel syndrome: exploring person-centered perspectives to better understand symptom severity scores. Value Health (2012) 0.75

Articles cited by this

The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care (1992) 144.02

Functional bowel disorders. Gastroenterology (2006) 20.72

Protective and damaging effects of stress mediators. N Engl J Med (1998) 18.80

Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain (2005) 11.80

U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci (1993) 7.98

The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress. Aliment Pharmacol Ther (1997) 5.78

Non-colonic features of irritable bowel syndrome. Gut (1986) 5.48

Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications? Gastroenterology (2002) 4.40

Systematic review on the management of irritable bowel syndrome in North America. Am J Gastroenterol (2002) 3.04

Further validation of the IBS-QOL: a disease-specific quality-of-life questionnaire. Am J Gastroenterol (2000) 2.95

Assessing global pain severity by self-report in clinical and health services research. Spine (Phila Pa 1976) (2000) 2.73

Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders. Gastroenterology (2006) 2.19

Psychosocial aspects of the functional gastrointestinal disorders. Gut (1999) 1.99

Health-related quality of life among persons with irritable bowel syndrome: a systematic review. Aliment Pharmacol Ther (2002) 1.97

Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome. Gastroenterology (1997) 1.94

Fibromyalgia in the irritable bowel syndrome: studies of prevalence and clinical implications. Am J Gastroenterol (1999) 1.61

Patient knowledge and educational needs in irritable bowel syndrome. Eur J Gastroenterol Hepatol (2000) 1.60

Levels of anxiety in colonic disorders. N Engl J Med (1973) 1.60

Primary endpoints for irritable bowel syndrome trials: a review of performance of endpoints. Clin Gastroenterol Hepatol (2007) 1.54

Alosetron controls bowel urgency and provides global symptom improvement in women with diarrhea-predominant irritable bowel syndrome. Am J Gastroenterol (2001) 1.51

Brain-gut connections in functional GI disorders: anatomic and physiologic relationships. Neurogastroenterol Motil (2006) 1.51

Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Arch Intern Med (2004) 1.51

Altered rectal perception in irritable bowel syndrome is associated with symptom severity. Gastroenterology (2007) 1.48

Irritable bowel syndrome: toward an understanding of severity. Clin Gastroenterol Hepatol (2005) 1.41

Functional bowel disorders. A multicenter comparison of health status and development of illness severity index. Dig Dis Sci (1995) 1.35

Beyond pain: the role of fear and avoidance in chronicity. Clin Psychol Rev (1999) 1.34

Do psychosocial factors define symptom severity and patient status in irritable bowel syndrome? Am J Med (1999) 1.32

What patients know about irritable bowel syndrome (IBS) and what they would like to know. National Survey on Patient Educational Needs in IBS and development and validation of the Patient Educational Needs Questionnaire (PEQ). Am J Gastroenterol (2007) 1.29

The impact of somatization on the use of gastrointestinal health-care resources in patients with irritable bowel syndrome. Am J Gastroenterol (2005) 1.28

Costs of care for irritable bowel syndrome patients in a health maintenance organization. Am J Gastroenterol (2001) 1.27

Doctor-dependent changes in complaint-related cognitions and anxiety during medical consultations in functional abdominal complaints. Psychol Med (1995) 1.25

Diagnosis of irritable bowel syndrome. Gastroenterology (2002) 1.25

The association of irritable bowel syndrome and somatization disorder. Ann Clin Psychiatry (2001) 1.22

Use of the Functional Bowel Disorder Severity Index (FBDSI) in a study of patients with the irritable bowel syndrome and fibromyalgia. Am J Gastroenterol (2000) 1.19

Medical and lay views of irritable bowel syndrome. Fam Pract (2000) 1.16

Effects of coping on health outcome among women with gastrointestinal disorders. Psychosom Med (2000) 1.14

Patient-perceived severity of irritable bowel syndrome in relation to symptoms, health resource utilization and quality of life. Aliment Pharmacol Ther (1997) 1.10

The patient's perspective of irritable bowel syndrome. J Fam Pract (2001) 1.07

The understanding of their illness amongst people with irritable bowel syndrome: a Q methodological study. Soc Sci Med (2000) 1.04

Family practitioners' attitudes and knowledge about irritable bowel syndrome: effect of a trial of physician education. Fam Pract (2003) 0.98

Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies. Gut (2006) 0.96

Effect of alosetron on bowel urgency and global symptoms in women with severe, diarrhea-predominant irritable bowel syndrome: analysis of two controlled trials. Clin Gastroenterol Hepatol (2004) 0.95

Towards a better understanding of patients with irritable bowel syndrome. J Adv Nurs (1993) 0.93

Biopsychosocial issues in irritable bowel syndrome. J Clin Gastroenterol (2005) 0.91

Discrepancies between patient-reported outcomes and clinician-reported outcomes in chronic venous disease, irritable bowel syndrome, and peripheral arterial occlusive disease. Value Health (2006) 0.90

Rectal sensation, pelvic floor function and symptom severity in Hispanic population with irritable bowel syndrome with constipation. Colorectal Dis (2006) 0.85

Evolving pathophysiological model of functional gastrointestinal disorders: implications for treatment. Eur J Surg Suppl (2002) 0.84

Impact of advertisement and clinic populations in symptoms and perception of irritable bowel syndrome. Aliment Pharmacol Ther (1999) 0.84

Bacterial concepts in irritable bowel syndrome. Rev Gastroenterol Disord (2005) 0.82

Articles by these authors

AGA technical review on irritable bowel syndrome. Gastroenterology (2002) 6.76

Studying sex and gender differences in pain and analgesia: a consensus report. Pain (2007) 3.58

Longitudinal change in perceptual and brain activation response to visceral stimuli in irritable bowel syndrome patients. Gastroenterology (2006) 2.95

A randomized placebo-controlled phase IIb trial of a3309, a bile acid transporter inhibitor, for chronic idiopathic constipation. Am J Gastroenterol (2011) 2.81

Neuroendocrine and neuroimmune markers in IBS: pathophysiological role or epiphenomenon? Gastroenterology (2006) 2.68

Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis. Pain (2005) 2.51

Psychosocial aspects of the functional gastrointestinal disorders. Gastroenterology (2006) 2.51

Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. J Neurosci (2004) 2.42

Sex-related differences in IBS patients: central processing of visceral stimuli. Gastroenterology (2003) 2.32

Consumption of fermented milk product with probiotic modulates brain activity. Gastroenterology (2013) 2.26

Principles and clinical implications of the brain-gut-enteric microbiota axis. Nat Rev Gastroenterol Hepatol (2009) 2.24

Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders. Gastroenterology (2006) 2.19

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. EMBO J (2011) 2.08

Is irritable bowel syndrome a diagnosis of exclusion?: a survey of primary care providers, gastroenterologists, and IBS experts. Am J Gastroenterol (2010) 2.02

Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia. Am J Physiol Gastrointest Liver Physiol (2005) 1.99

Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun (2004) 1.98

Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology (2010) 1.90

Serum and colonic mucosal immune markers in irritable bowel syndrome. Am J Gastroenterol (2011) 1.89

Is a negative colonoscopy associated with reassurance or improved health-related quality of life in irritable bowel syndrome? Gastrointest Endosc (2005) 1.88

Psychometric properties of the Early Trauma Inventory-Self Report. J Nerv Ment Dis (2007) 1.81

Reduced brainstem inhibition during anticipated pelvic visceral pain correlates with enhanced brain response to the visceral stimulus in women with irritable bowel syndrome. J Neurosci (2008) 1.77

Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel syndrome. Pain (2013) 1.77

Regional gray matter density changes in brains of patients with irritable bowel syndrome. Gastroenterology (2010) 1.75

Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Res (2011) 1.74

Aberrant Schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy. Neuron (2013) 1.70

The neural correlates of placebo effects: a disruption account. Neuroimage (2004) 1.68

The central role of gastrointestinal-specific anxiety in irritable bowel syndrome: further validation of the visceral sensitivity index. Psychosom Med (2007) 1.65

Gut/brain axis and the microbiota. J Clin Invest (2015) 1.64

An update on the use and investigation of probiotics in health and disease. Gut (2013) 1.62

A comparison of visceral and somatic pain processing in the human brainstem using functional magnetic resonance imaging. J Neurosci (2005) 1.60

The MAPP research network: design, patient characterization and operations. BMC Urol (2014) 1.56

Primary endpoints for irritable bowel syndrome trials: a review of performance of endpoints. Clin Gastroenterol Hepatol (2007) 1.54

Characterization of the alternating bowel habit subtype in patients with irritable bowel syndrome. Am J Gastroenterol (2005) 1.52

Attachment figures activate a safety signal-related neural region and reduce pain experience. Proc Natl Acad Sci U S A (2011) 1.51

Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Arch Intern Med (2004) 1.51

An experimental study of shared sensitivity to physical pain and social rejection. Pain (2006) 1.50

Irritable bowel syndrome patients show enhanced modulation of visceral perception by auditory stress. Am J Gastroenterol (2003) 1.50

One-year test-retest reliability of intrinsic connectivity network fMRI in older adults. Neuroimage (2012) 1.47

The MAPP research network: a novel study of urologic chronic pelvic pain syndromes. BMC Urol (2014) 1.47

Diminished neurokinin-1 receptor availability in patients with two forms of chronic visceral pain. Pain (2013) 1.45

Pain medication beliefs and medication misuse in chronic pain. J Pain (2005) 1.44

Developing irritable bowel syndrome guidelines through meta-analyses: does the emperor really have new clothes? Gastroenterology (2009) 1.43

Impact of Mindfulness-Based Stress Reduction training on intrinsic brain connectivity. Neuroimage (2011) 1.42

Prevalence of irritable bowel syndrome among university students: the roles of worry, neuroticism, anxiety sensitivity and visceral anxiety. J Psychosom Res (2003) 1.40

Psychological risk factors for HIV pathogenesis: mediation by the autonomic nervous system. Biol Psychiatry (2003) 1.38

Association between early adverse life events and irritable bowel syndrome. Clin Gastroenterol Hepatol (2011) 1.35

Nitro-oleic acid inhibits angiotensin II-induced hypertension. Circ Res (2010) 1.34

Childhood trauma is associated with hypothalamic-pituitary-adrenal axis responsiveness in irritable bowel syndrome. Gastroenterology (2009) 1.33

The addiction behaviors checklist: validation of a new clinician-based measure of inappropriate opioid use in chronic pain. J Pain Symptom Manage (2006) 1.32

Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis. Development (2004) 1.29

Do fluctuations in ovarian hormones affect gastrointestinal symptoms in women with irritable bowel syndrome? Gend Med (2009) 1.28

The effect of life stress on symptoms of heartburn. Psychosom Med (2004) 1.28

PPARs and the cardiovascular system. Antioxid Redox Signal (2009) 1.28

Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosom Med (2014) 1.24

A picture's worth: partner photographs reduce experimentally induced pain. Psychol Sci (2009) 1.24

Sex-based differences in gastrointestinal pain. Eur J Pain (2004) 1.23

Role of astrocytes and altered regulation of spinal glutamatergic neurotransmission in stress-induced visceral hyperalgesia in rats. Am J Physiol Gastrointest Liver Physiol (2011) 1.22

Brain responses to visceral stimuli reflect visceral sensitivity thresholds in patients with irritable bowel syndrome. Gastroenterology (2011) 1.22

Effect of abuse history on pain reports and brain responses to aversive visceral stimulation: an FMRI study. Gastroenterology (2007) 1.22

The effect of auditory stress on perception of intraesophageal acid in patients with gastroesophageal reflux disease. Gastroenterology (2007) 1.19

A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations. Behav Res Ther (2011) 1.18

Genetic approaches to functional gastrointestinal disorders. Gastroenterology (2010) 1.18

Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21. Endocrinology (2014) 1.18

Functional abdominal pain syndrome. Gastroenterology (2006) 1.16

Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. EMBO J (2013) 1.15

Effect of sex on perception of rectosigmoid stimuli in irritable bowel syndrome. Am J Physiol Regul Integr Comp Physiol (2006) 1.14

Challenges to the therapeutic pipeline for irritable bowel syndrome: end points and regulatory hurdles. Gastroenterology (2008) 1.14

Diagnosis and management of IBS. Nat Rev Gastroenterol Hepatol (2010) 1.14

Panic disorder and pain in a national sample of persons living with HIV. Pain (2004) 1.13

Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats. Am J Physiol Gastrointest Liver Physiol (2005) 1.12

Validation of a symptom provocation test for laboratory studies of abdominal pain and discomfort in children and adolescents. J Pediatr Psychol (2006) 1.12

Two N-methyl-D-aspartate receptors in rat dorsal root ganglia with different subunit composition and localization. J Comp Neurol (2002) 1.12