Published in Clin Gastroenterol Hepatol on December 16, 2011
Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosom Med (2014) 1.24
Gender-related differences in irritable bowel syndrome: potential mechanisms of sex hormones. World J Gastroenterol (2014) 1.03
Microbiota and host determinants of behavioural phenotype in maternally separated mice. Nat Commun (2015) 1.01
Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain (2013) 1.01
Building a second brain in the bowel. J Clin Invest (2015) 0.99
Why dyspepsia can occur without organic disease: pathogenesis and management of functional dyspepsia. J Gastroenterol (2012) 0.99
Towards a systems view of IBS. Nat Rev Gastroenterol Hepatol (2015) 0.97
Early life factors initiate a 'vicious circle' of affective and gastrointestinal symptoms: A longitudinal study. United European Gastroenterol J (2013) 0.93
Chronic Early-life Stress in Rat Pups Alters Basal Corticosterone, Intestinal Permeability, and Fecal Microbiota at Weaning: Influence of Sex. J Neurogastroenterol Motil (2016) 0.89
Early life adversity as a risk factor for visceral pain in later life: importance of sex differences. Front Neurosci (2013) 0.84
Neonatal stress from limited bedding elicits visceral hyperalgesia in adult rats. Neuroreport (2015) 0.83
Developmental origins of colon smooth muscle dysfunction in IBS-like rats. Am J Physiol Gastrointest Liver Physiol (2013) 0.83
Mast Cells and Irritable Bowel Syndrome: From the Bench to the Bedside. J Neurogastroenterol Motil (2016) 0.83
Impact of psychological stress on irritable bowel syndrome. World J Gastroenterol (2014) 0.82
Chronic prenatal stress epigenetically modifies spinal cord BDNF expression to induce sex-specific visceral hypersensitivity in offspring. Neurogastroenterol Motil (2014) 0.81
Early-life stress origins of gastrointestinal disease: animal models, intestinal pathophysiology, and translational implications. Am J Physiol Gastrointest Liver Physiol (2015) 0.81
Cognitive behavioral approach to understanding irritable bowel syndrome. World J Gastroenterol (2014) 0.81
Irritable bowel syndrome in children: pathogenesis, diagnosis and evidence-based treatment. World J Gastroenterol (2014) 0.80
Early-life dietary spray-dried plasma influences immunological and intestinal injury responses to later-life Salmonella typhimurium challenge. Br J Nutr (2015) 0.79
The impact of abuse and mood on bowel symptoms and health-related quality of life in irritable bowel syndrome (IBS). Neurogastroenterol Motil (2016) 0.77
Heightened Temporal Summation of Pain in Patients with Functional Gastrointestinal Disorders and History of Trauma. Ann Behav Med (2015) 0.77
Abdominal Pain, the Adolescent and Altered Brain Structure and Function. PLoS One (2016) 0.77
Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PLoS One (2016) 0.77
Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PLoS One (2015) 0.77
Adult cyclical vomiting syndrome: a disorder of allostatic regulation? Exp Brain Res (2014) 0.76
Sex-related differences in pain behaviors following three early life stress paradigms. Biol Sex Differ (2016) 0.76
Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain Struct Funct (2015) 0.76
Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses. Neurogastroenterol Motil (2016) 0.76
Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterol Motil (2016) 0.76
New and emerging therapies for the treatment of irritable bowel syndrome: an update for gastroenterologists. Therap Adv Gastroenterol (2016) 0.76
IRRITABLE BOWEL SYNDROME: Relationships with Abuse in Childhood. Innov Clin Neurosci (2015) 0.76
The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology (2016) 0.76
Stress and glucocorticoid receptor transcriptional programming in time and space: Implications for the brain-gut axis. Neurogastroenterol Motil (2016) 0.75
Maternal Separation Induced Visceral Hypersensitivity from Childhood to Adulthood. J Neurogastroenterol Motil (2017) 0.75
Chronic social stress in pigs impairs intestinal barrier and nutrient transporter function, and alters neuro-immune mediator and receptor expression. PLoS One (2017) 0.75
Irritable bowel syndrome: What physicians should know? J Neurosci Rural Pract (2016) 0.75
Irritable Bowel Syndrome: A gut microbiota-related disorder? Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterol Motil (2015) 0.75
Sex-specific impact of early-life adversity on chronic pain: a large population-based study in Japan. J Pain Res (2017) 0.75
Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. Psychoneuroendocrinology (2016) 0.75
The Impact of Prenatal Exposure to Dexamethasone on Gastrointestinal Function in Rats. PLoS One (2016) 0.75
Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiol Stress (2016) 0.75
A Review of Select Centralized Pain Syndromes: Relationship With Childhood Sexual Abuse, Opiate Prescribing, and Treatment Implications for the Primary Care Physician. Health Serv Res Manag Epidemiol (2015) 0.75
Early adverse life events are associated with altered brain network architecture in a sex- dependent manner. Neurobiol Stress (2017) 0.75
Emotional awareness and expression training improves irritable bowel syndrome: A randomized controlled trial. Neurogastroenterol Motil (2017) 0.75
Endocrine dysregulation in women with irritable bowel syndrome according to Rome II criteria. J Behav Med (2016) 0.75
Early-life adversity, epigenetics, and visceral hypersensitivity. Neurogastroenterol Motil (2017) 0.75
Early weaning stress induces chronic functional diarrhea, intestinal barrier defects, and increased mast cell activity in a porcine model of early life adversity. Neurogastroenterol Motil (2017) 0.75
The hospital anxiety and depression scale. Acta Psychiatr Scand (1983) 121.58
Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med (1998) 31.43
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci (2009) 10.17
Functional somatic syndromes. Ann Intern Med (1999) 9.67
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry (2001) 7.80
Functional bowel disorders and functional abdominal pain. Gut (1999) 7.63
The enduring effects of abuse and related adverse experiences in childhood. A convergence of evidence from neurobiology and epidemiology. Eur Arch Psychiatry Clin Neurosci (2005) 7.21
Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. JAMA (2000) 7.21
The PHQ-15: validity of a new measure for evaluating the severity of somatic symptoms. Psychosom Med (2002) 6.10
Adverse childhood experiences and smoking during adolescence and adulthood. JAMA (1999) 6.09
Sexual and physical abuse in women with functional or organic gastrointestinal disorders. Ann Intern Med (1990) 3.46
Gastric suction at birth associated with long-term risk for functional intestinal disorders in later life. J Pediatr (2004) 3.16
Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma. Proc Natl Acad Sci U S A (2003) 2.56
Health status by gastrointestinal diagnosis and abuse history. Gastroenterology (1996) 2.41
V. Stress and irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol (2001) 2.19
Gastrointestinal tract symptoms and self-reported abuse: a population-based study. Gastroenterology (1994) 2.12
Neonatal maternal separation alters stress-induced responses to viscerosomatic nociceptive stimuli in rat. Am J Physiol Gastrointest Liver Physiol (2002) 2.10
Gender, age, society, culture, and the patient's perspective in the functional gastrointestinal disorders. Gastroenterology (2006) 1.97
Early life risk factors that contribute to irritable bowel syndrome in adults: a systematic review. Am J Gastroenterol (2008) 1.85
Psychometric properties of the Early Trauma Inventory-Self Report. J Nerv Ment Dis (2007) 1.81
Irritable bowel syndrome in twins: genes and environment. Gut (2006) 1.81
The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom-specific anxiety scale. Aliment Pharmacol Ther (2004) 1.76
Sexual and physical abuse history in gastroenterology practice: how types of abuse impact health status. Psychosom Med (1996) 1.74
The Spielberger State-Trait Anxiety Inventory (STAI): the state scale in detecting mental disorders in geriatric patients. Int J Geriatr Psychiatry (2005) 1.74
Selected symptoms associated with sexual and physical abuse history among female patients with gastrointestinal disorders: the impact on subsequent health care visits. Psychol Med (1998) 1.74
Adverse childhood experiences and chronic obstructive pulmonary disease in adults. Am J Prev Med (2008) 1.56
Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation. Endocrinology (1996) 1.48
Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in irritable bowel syndrome. Neurogastroenterol Motil (2008) 1.41
Neonatal maternal separation of rat pups results in abnormal cholinergic regulation of epithelial permeability. Am J Physiol Gastrointest Liver Physiol (2007) 1.38
Irritable bowel-type symptoms in HMO examinees. Prevalence, demographics, and clinical correlates. Dig Dis Sci (1993) 1.33
Childhood trauma is associated with hypothalamic-pituitary-adrenal axis responsiveness in irritable bowel syndrome. Gastroenterology (2009) 1.33
Abuse, dissociation, and somatization in irritable bowel syndrome: towards an explanatory model. J Behav Med (2003) 1.29
Neonatal maternal separation causes colonic dysfunction in rat pups including impaired host resistance. Pediatr Res (2005) 1.28
Adverse childhood experiences and prescription drug use in a cohort study of adult HMO patients. BMC Public Health (2008) 1.26
Diet and the epigenetic (re)programming of phenotypic differences in behavior. Brain Res (2008) 1.22
Functional dyspepsia. Therap Adv Gastroenterol (2010) 1.17
Childhood deprivation: an antecedent of the irritable bowel syndrome. Med J Aust (1979) 0.97
The relationship between somatisation and outcome in patients with severe irritable bowel syndrome. J Psychosom Res (2008) 0.92
Risk factors for impaired health-related quality of life in functional dyspepsia. Aliment Pharmacol Ther (2010) 0.90
Effect of childhood adversity on health related quality of life in patients with upper abdominal or chest pain. Gut (2004) 0.84
AGA technical review on irritable bowel syndrome. Gastroenterology (2002) 6.76
Studying sex and gender differences in pain and analgesia: a consensus report. Pain (2007) 3.58
Longitudinal change in perceptual and brain activation response to visceral stimuli in irritable bowel syndrome patients. Gastroenterology (2006) 2.95
A randomized placebo-controlled phase IIb trial of a3309, a bile acid transporter inhibitor, for chronic idiopathic constipation. Am J Gastroenterol (2011) 2.81
Neuroendocrine and neuroimmune markers in IBS: pathophysiological role or epiphenomenon? Gastroenterology (2006) 2.68
Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis. Pain (2005) 2.51
Psychosocial aspects of the functional gastrointestinal disorders. Gastroenterology (2006) 2.51
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. J Neurosci (2004) 2.42
Sex-related differences in IBS patients: central processing of visceral stimuli. Gastroenterology (2003) 2.32
Consumption of fermented milk product with probiotic modulates brain activity. Gastroenterology (2013) 2.26
Principles and clinical implications of the brain-gut-enteric microbiota axis. Nat Rev Gastroenterol Hepatol (2009) 2.24
Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders. Gastroenterology (2006) 2.19
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. EMBO J (2011) 2.08
Is irritable bowel syndrome a diagnosis of exclusion?: a survey of primary care providers, gastroenterologists, and IBS experts. Am J Gastroenterol (2010) 2.02
Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia. Am J Physiol Gastrointest Liver Physiol (2005) 1.99
Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun (2004) 1.98
Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology (2010) 1.90
Serum and colonic mucosal immune markers in irritable bowel syndrome. Am J Gastroenterol (2011) 1.89
Is a negative colonoscopy associated with reassurance or improved health-related quality of life in irritable bowel syndrome? Gastrointest Endosc (2005) 1.88
Psychometric properties of the Early Trauma Inventory-Self Report. J Nerv Ment Dis (2007) 1.81
Reduced brainstem inhibition during anticipated pelvic visceral pain correlates with enhanced brain response to the visceral stimulus in women with irritable bowel syndrome. J Neurosci (2008) 1.77
Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel syndrome. Pain (2013) 1.77
Regional gray matter density changes in brains of patients with irritable bowel syndrome. Gastroenterology (2010) 1.75
Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Res (2011) 1.74
The neural correlates of placebo effects: a disruption account. Neuroimage (2004) 1.68
The central role of gastrointestinal-specific anxiety in irritable bowel syndrome: further validation of the visceral sensitivity index. Psychosom Med (2007) 1.65
Gut/brain axis and the microbiota. J Clin Invest (2015) 1.64
An update on the use and investigation of probiotics in health and disease. Gut (2013) 1.62
A comparison of visceral and somatic pain processing in the human brainstem using functional magnetic resonance imaging. J Neurosci (2005) 1.60
The MAPP research network: design, patient characterization and operations. BMC Urol (2014) 1.56
Primary endpoints for irritable bowel syndrome trials: a review of performance of endpoints. Clin Gastroenterol Hepatol (2007) 1.54
Characterization of the alternating bowel habit subtype in patients with irritable bowel syndrome. Am J Gastroenterol (2005) 1.52
Attachment figures activate a safety signal-related neural region and reduce pain experience. Proc Natl Acad Sci U S A (2011) 1.51
Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Arch Intern Med (2004) 1.51
An experimental study of shared sensitivity to physical pain and social rejection. Pain (2006) 1.50
Irritable bowel syndrome patients show enhanced modulation of visceral perception by auditory stress. Am J Gastroenterol (2003) 1.50
Timing, duration, and severity of hyponatremia following pediatric brain tumor surgery*. Pediatr Crit Care Med (2014) 1.49
One-year test-retest reliability of intrinsic connectivity network fMRI in older adults. Neuroimage (2012) 1.47
The MAPP research network: a novel study of urologic chronic pelvic pain syndromes. BMC Urol (2014) 1.47
Diminished neurokinin-1 receptor availability in patients with two forms of chronic visceral pain. Pain (2013) 1.45
Pain medication beliefs and medication misuse in chronic pain. J Pain (2005) 1.44
Developing irritable bowel syndrome guidelines through meta-analyses: does the emperor really have new clothes? Gastroenterology (2009) 1.43
Impact of Mindfulness-Based Stress Reduction training on intrinsic brain connectivity. Neuroimage (2011) 1.42
Prevalence of irritable bowel syndrome among university students: the roles of worry, neuroticism, anxiety sensitivity and visceral anxiety. J Psychosom Res (2003) 1.40
Psychological risk factors for HIV pathogenesis: mediation by the autonomic nervous system. Biol Psychiatry (2003) 1.38
Predictors of patient-assessed illness severity in irritable bowel syndrome. Am J Gastroenterol (2008) 1.35
Nitro-oleic acid inhibits angiotensin II-induced hypertension. Circ Res (2010) 1.34
Childhood trauma is associated with hypothalamic-pituitary-adrenal axis responsiveness in irritable bowel syndrome. Gastroenterology (2009) 1.33
The addiction behaviors checklist: validation of a new clinician-based measure of inappropriate opioid use in chronic pain. J Pain Symptom Manage (2006) 1.32
Do fluctuations in ovarian hormones affect gastrointestinal symptoms in women with irritable bowel syndrome? Gend Med (2009) 1.28
The effect of life stress on symptoms of heartburn. Psychosom Med (2004) 1.28
PPARs and the cardiovascular system. Antioxid Redox Signal (2009) 1.28
Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosom Med (2014) 1.24
A picture's worth: partner photographs reduce experimentally induced pain. Psychol Sci (2009) 1.24
Sex-based differences in gastrointestinal pain. Eur J Pain (2004) 1.23
Role of astrocytes and altered regulation of spinal glutamatergic neurotransmission in stress-induced visceral hyperalgesia in rats. Am J Physiol Gastrointest Liver Physiol (2011) 1.22
Brain responses to visceral stimuli reflect visceral sensitivity thresholds in patients with irritable bowel syndrome. Gastroenterology (2011) 1.22
Effect of abuse history on pain reports and brain responses to aversive visceral stimulation: an FMRI study. Gastroenterology (2007) 1.22
The effect of auditory stress on perception of intraesophageal acid in patients with gastroesophageal reflux disease. Gastroenterology (2007) 1.19
A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations. Behav Res Ther (2011) 1.18
Genetic approaches to functional gastrointestinal disorders. Gastroenterology (2010) 1.18
Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21. Endocrinology (2014) 1.18
Functional abdominal pain syndrome. Gastroenterology (2006) 1.16
Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. EMBO J (2013) 1.15
Effect of sex on perception of rectosigmoid stimuli in irritable bowel syndrome. Am J Physiol Regul Integr Comp Physiol (2006) 1.14
Challenges to the therapeutic pipeline for irritable bowel syndrome: end points and regulatory hurdles. Gastroenterology (2008) 1.14
Diagnosis and management of IBS. Nat Rev Gastroenterol Hepatol (2010) 1.14
Panic disorder and pain in a national sample of persons living with HIV. Pain (2004) 1.13
Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats. Am J Physiol Gastrointest Liver Physiol (2005) 1.12