Published in Nucleic Acids Res on July 21, 2008
Highlights of the DNA cutters: a short history of the restriction enzymes. Nucleic Acids Res (2013) 1.60
Systematic prediction of control proteins and their DNA binding sites. Nucleic Acids Res (2008) 1.10
Conflicts targeting epigenetic systems and their resolution by cell death: novel concepts for methyl-specific and other restriction systems. DNA Res (2010) 1.06
Transcription regulation of restriction-modification system Esp1396I. Nucleic Acids Res (2009) 0.96
Tuning the relative affinities for activating and repressing operators of a temporally regulated restriction-modification system. Nucleic Acids Res (2009) 0.88
Crystal structure of the P2 C-repressor: a binder of non-palindromic direct DNA repeats. Nucleic Acids Res (2010) 0.86
Radiation damage to nucleoprotein complexes in macromolecular crystallography. J Synchrotron Radiat (2015) 0.86
RNA protects a nucleoprotein complex against radiation damage. Acta Crystallogr D Struct Biol (2016) 0.84
Recognition of dual symmetry by the controller protein C.Esp1396I based on the structure of the transcriptional activation complex. Nucleic Acids Res (2011) 0.84
Re-visiting protein-centric two-tier classification of existing DNA-protein complexes. BMC Bioinformatics (2012) 0.84
The structural basis of differential DNA sequence recognition by restriction-modification controller proteins. Nucleic Acids Res (2012) 0.84
Structural analysis of a novel class of R-M controller proteins: C.Csp231I from Citrobacter sp. RFL231. J Mol Biol (2011) 0.82
Translational independence between overlapping genes for a restriction endonuclease and its transcriptional regulator. BMC Mol Biol (2010) 0.81
BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ. Nucleic Acids Res (2014) 0.80
Predicting the effects of basepair mutations in DNA-protein complexes by thermodynamic integration. Biophys J (2011) 0.79
Structural analysis of DNA-protein complexes regulating the restriction-modification system Esp1396I. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.79
Overexpression, purification and preliminary X-ray diffraction analysis of the controller protein C.Csp231I from Citrobacter sp. RFL231. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.78
Structural and mutagenic analysis of the RM controller protein C.Esp1396I. PLoS One (2014) 0.78
Naturally-occurring, dually-functional fusions between restriction endonucleases and regulatory proteins. BMC Evol Biol (2013) 0.77
Structural analysis of DNA binding by C.Csp231I, a member of a novel class of R-M controller proteins regulating gene expression. Acta Crystallogr D Biol Crystallogr (2015) 0.77
Physical basis of the inducer-dependent cooperativity of the Central glycolytic genes Repressor/DNA complex. Nucleic Acids Res (2010) 0.77
Natural C-independent expression of restriction endonuclease in a C protein-associated restriction-modification system. Nucleic Acids Res (2015) 0.75
APTE: identification of indirect read-out A-DNA promoter elements in genomes. BMC Bioinformatics (2014) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43
Likelihood-enhanced fast translation functions. Acta Crystallogr D Biol Crystallogr (2005) 29.38
The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids. J Biomol Struct Dyn (1988) 9.26
Recent developments in the PHENIX software for automated crystallographic structure determination. J Synchrotron Radiat (2003) 6.28
Restriction and modification systems. Annu Rev Genet (1991) 5.91
Three-dimensional structure of the Stat3beta homodimer bound to DNA. Nature (1998) 5.04
On the mechanism of the development of multiple-drug-resistant clones of Shigella. Jpn J Microbiol (1960) 4.69
DNA bending: the prevalence of kinkiness and the virtues of normality. Nucleic Acids Res (1998) 3.67
Functional specificity of a Hox protein mediated by the recognition of minor groove structure. Cell (2007) 3.34
SRY, like HMG1, recognizes sharp angles in DNA. EMBO J (1992) 3.29
Catabolite activator protein: DNA binding and transcription activation. Curr Opin Struct Biol (2004) 2.91
NUCPLOT: a program to generate schematic diagrams of protein-nucleic acid interactions. Nucleic Acids Res (1997) 2.81
A family of regulatory genes associated with type II restriction-modification systems. J Bacteriol (1991) 2.60
How proteins recognize the TATA box. J Mol Biol (1996) 2.60
Regulation of the BamHI restriction-modification system by a small intergenic open reading frame, bamHIC, in both Escherichia coli and Bacillus subtilis. J Bacteriol (1992) 1.72
Role and mechanism of action of C. PvuII, a regulatory protein conserved among restriction-modification systems. J Bacteriol (2000) 1.60
Measuring the geometry of DNA grooves. Biopolymers (1994) 1.40
Nature of the promoter activated by C.PvuII, an unusual regulatory protein conserved among restriction-modification systems. J Bacteriol (2005) 1.36
High-resolution crystal structure of the restriction-modification controller protein C.AhdI from Aeromonas hydrophila. J Mol Biol (2005) 1.30
Esp1396I restriction-modification system: structural organization and mode of regulation. Nucleic Acids Res (2003) 1.26
Transcription regulation of the type II restriction-modification system AhdI. Nucleic Acids Res (2008) 1.23
DNA footprinting and biophysical characterization of the controller protein C.AhdI suggests the basis of a genetic switch. Nucleic Acids Res (2004) 1.18
Real-time kinetics of restriction-modification gene expression after entry into a new host cell. Nucleic Acids Res (2008) 1.17
Crystal structure of the restriction-modification system control element C.Bcll and mapping of its binding site. Structure (2005) 1.12
Cooperative binding of the C.AhdI controller protein to the C/R promoter and its role in endonuclease gene expression. J Mol Biol (2006) 1.10
How Cro and lambda-repressor distinguish between operators: the structural basis underlying a genetic switch. Proc Natl Acad Sci U S A (1998) 1.07
Improved plasmid vectors for the analysis of protein-induced DNA bending. Methods Mol Biol (1994) 1.06
Regulatory circuit based on autogenous activation-repression: roles of C-boxes and spacer sequences in control of the PvuII restriction-modification system. Nucleic Acids Res (2007) 1.06
Crystal structure of bacteriophage lambda cII and its DNA complex. Mol Cell (2005) 1.04
DNA structural deformations in the interaction of the controller protein C.AhdI with its operator sequence. Nucleic Acids Res (2007) 1.03
Three-dimensional intricacies in protein-DNA recognition and transcriptional control. Nat Struct Mol Biol (2007) 0.81
Zero-dose extrapolation as part of macromolecular synchrotron data reduction. Acta Crystallogr D Biol Crystallogr (2003) 12.96
Crystal structure of the rabies virus nucleoprotein-RNA complex. Science (2006) 3.48
Structural basis for the regulation of tubulin by vinblastine. Nature (2005) 3.10
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes. Nat Struct Mol Biol (2004) 2.46
Phasing macromolecular structures with UV-induced structural changes. Structure (2006) 1.94
Improving radiation-damage substructures for RIP. Acta Crystallogr D Biol Crystallogr (2005) 1.80
Improving diffraction by humidity control: a novel device compatible with X-ray beamlines. Acta Crystallogr D Biol Crystallogr (2009) 1.73
MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments. J Synchrotron Radiat (2010) 1.71
A decade of user operation on the macromolecular crystallography MAD beamline ID14-4 at the ESRF. J Synchrotron Radiat (2009) 1.64
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin. Proc Natl Acad Sci U S A (2009) 1.59
Structural insights into the Slit-Robo complex. Proc Natl Acad Sci U S A (2007) 1.54
Structure of dimeric SecA, the Escherichia coli preprotein translocase motor. J Mol Biol (2006) 1.53
Colouring cryo-cooled crystals: online microspectrophotometry. J Synchrotron Radiat (2009) 1.51
Structural insight into the inhibition of tubulin by vinca domain peptide ligands. EMBO Rep (2008) 1.32
Is radiation damage dependent on the dose rate used during macromolecular crystallography data collection? Acta Crystallogr D Biol Crystallogr (2006) 1.32
Virtual nanoscopy: generation of ultra-large high resolution electron microscopy maps. J Cell Biol (2012) 1.31
Parameters affecting the X-ray dose absorbed by macromolecular crystals. J Synchrotron Radiat (2005) 1.26
X-ray crystallographic and NMR studies of the third KH domain of hnRNP K in complex with single-stranded nucleic acids. Structure (2005) 1.24
The solution and crystal structures of a module pair from the Staphylococcus aureus-binding site of human fibronectin--a tale with a twist. J Mol Biol (2007) 1.24
Strain relief at the active site of phosphoserine aminotransferase induced by radiation damage. Protein Sci (2005) 1.19
C3D: a program for the automated centring of cryocooled crystals. Acta Crystallogr D Biol Crystallogr (2006) 1.17
Conversion of mature human β-cells into glucagon-producing α-cells. Diabetes (2013) 1.16
Initial events in the photocycle of photoactive yellow protein. J Biol Chem (2004) 1.14
Structure and operation of the DNA-translocating type I DNA restriction enzymes. Genes Dev (2012) 1.13
Evidence for the formation of disulfide radicals in protein crystals upon X-ray irradiation. J Synchrotron Radiat (2002) 1.12
The use of a mini-κ goniometer head in macromolecular crystallography diffraction experiments. Acta Crystallogr D Biol Crystallogr (2013) 1.09
The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin. J Mol Biol (2008) 1.04
X-ray radiation-induced damage in DNA monitored by online Raman. J Synchrotron Radiat (2006) 1.01
HsdR subunit of the type I restriction-modification enzyme EcoR124I: biophysical characterisation and structural modelling. J Mol Biol (2007) 1.00
Radiation damage in single-particle cryo-electron microscopy: effects of dose and dose rate. J Synchrotron Radiat (2011) 1.00
Tryparedoxins from Crithidia fasciculata and Trypanosoma brucei: photoreduction of the redox disulfide using synchrotron radiation and evidence for a conformational switch implicated in function. J Biol Chem (2003) 0.98
Translation calibration of inverse-kappa goniometers in macromolecular crystallography. Acta Crystallogr A (2011) 0.96
Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance. Proc Natl Acad Sci U S A (2013) 0.94
Cartilage ultrastructure in proteoglycan-deficient zebrafish mutants brings to light new candidate genes for human skeletal disorders. J Pathol (2011) 0.93
Differential specific radiation damage in the Cu II-bound and Pd II-bound forms of an alpha-helical foldamer: a case study of crystallographic phasing by RIP and SAD. Acta Crystallogr D Biol Crystallogr (2008) 0.91
Radiation stability of proteinase K crystals grown by LB nanotemplate method. J Struct Biol (2009) 0.88
Glomerular endothelial surface layer acts as a barrier against albumin filtration. Am J Pathol (2013) 0.88
Infrared protein crystallography. Biochim Biophys Acta (2011) 0.88
Design and characterization of modular scaffolds for tubulin assembly. J Biol Chem (2012) 0.86
3-D structure of serum paraoxonase 1 sheds light on its activity, stability, solubility and crystallizability. Arh Hig Rada Toksikol (2007) 0.85
Large multimeric assemblies of nucleosome assembly protein and histones revealed by small-angle X-ray scattering and electron microscopy. J Biol Chem (2012) 0.84
Structural and functional analysis of the engineered type I DNA methyltransferase EcoR124I(NT). J Mol Biol (2010) 0.84
Image formation modeling in cryo-electron microscopy. J Struct Biol (2013) 0.83
A new approach to improve the quality of ultrathin cryo-sections; its use for immunogold EM and correlative electron cryo-tomography. J Struct Biol (2011) 0.83
Alternative splicing determines the interaction of SMRT isoforms with nuclear receptor-DNA complexes. Biosci Rep (2009) 0.82
Fluorescence spectroscopy and anisotropy in the analysis of DNA-protein interactions. Methods Mol Biol (2009) 0.81
Expression, crystallization and crystallographic analysis of DegS, a stress sensor of the bacterial periplasm. Acta Crystallogr D Biol Crystallogr (2004) 0.81
Defocus estimation from stroboscopic cryo-electron microscopy data. Ultramicroscopy (2011) 0.81
Structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle. Acta Crystallogr D Biol Crystallogr (2009) 0.80
Non-random mtDNA segregation patterns indicate a metastable heteroplasmic segregation unit in m.3243A>G cybrid cells. PLoS One (2012) 0.80
Predicting the effects of basepair mutations in DNA-protein complexes by thermodynamic integration. Biophys J (2011) 0.79
Structural analysis of DNA-protein complexes regulating the restriction-modification system Esp1396I. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.79
Circular dichroism for the analysis of protein-DNA interactions. Methods Mol Biol (2009) 0.78
Structural and functional characterisation of the DNA binding domain of the Aspergillus nidulans gene regulatory protein AreA. Biochim Biophys Acta (2003) 0.77
A competition assay for DNA binding using the fluorescent probe ANS. Methods Mol Biol (2009) 0.76
Non-rigid image registration to reduce beam-induced blurring of cryo-electron microscopy images. J Synchrotron Radiat (2012) 0.75
The Max-Inf2/Lorentz Center workshop on New algorithms in macromolecular crystallography and electron microscopy. Acta Crystallogr D Biol Crystallogr (2009) 0.75
Crystallization, microPIXE and preliminary crystallographic analysis of the complex between the third KH domain of hnRNP K and single-stranded DNA. Acta Crystallogr D Biol Crystallogr (2004) 0.75
A rapid purification procedure for the HsdM protein of EcoR124I and biophysical characterization of the purified protein. Protein Expr Purif (2012) 0.75