Published in Crit Rev Eukaryot Gene Expr on January 01, 2008
Congenic mice provide in vivo evidence for a genetic locus that modulates intrinsic transforming growth factor β1-mediated signaling and bone acquisition. J Bone Miner Res (2012) 1.41
High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. J Bone Miner Res (2009) 1.09
Genetically determined phenotype covariation networks control bone strength. J Bone Miner Res (2010) 1.06
Heterogeneous stock rat: a unique animal model for mapping genes influencing bone fragility. Bone (2011) 0.83
How genomics has informed our understanding of the pathogenesis of osteoporosis. Genome Med (2009) 0.77
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Circulating levels of IGF-1 directly regulate bone growth and density. J Clin Invest (2002) 3.86
Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J Am Chem Soc (2013) 1.90
Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. J Bone Miner Res (2003) 1.78
Ovariectomy-induced bone loss varies among inbred strains of mice. J Bone Miner Res (2005) 1.70
Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program. Bone (2004) 1.53
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res (2003) 1.52
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis (2009) 1.44
Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains. J Bone Miner Res (2003) 1.37
PGMapper: a web-based tool linking phenotype to genes. Bioinformatics (2008) 1.34
Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. Genomics (2002) 1.29
Generation of a new congenic mouse strain to test the relationships among serum insulin-like growth factor I, bone mineral density, and skeletal morphology in vivo. J Bone Miner Res (2002) 1.28
Carbonic anhydrase-related protein VIII deficiency is associated with a distinctive lifelong gait disorder in waddles mice. Genetics (2005) 1.25
Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. Genome Res (2007) 1.21
A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model. PLoS One (2012) 1.20
Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. J Bone Miner Res (2006) 1.19
Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice. Funct Integr Genomics (2002) 1.18
Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice. J Bone Miner Res (2005) 1.17
20S-hydroxyvitamin D3, noncalcemic product of CYP11A1 action on vitamin D3, exhibits potent antifibrogenic activity in vivo. J Clin Endocrinol Metab (2013) 1.17
Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. Hum Mol Genet (2004) 1.16
Evidence for a skeletal mechanosensitivity gene on mouse chromosome 4. FASEB J (2002) 1.14
Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains. J Lipid Res (2007) 1.11
Loss-of-function mutations in HPSE2 cause the autosomal recessive urofacial syndrome. Am J Hum Genet (2010) 1.10
Quantitative trait loci for BMD in an SM/J by NZB/BlNJ intercross population and identification of Trps1 as a probable candidate gene. J Bone Miner Res (2008) 1.10
Vitamin D analogs 17,20S(OH)2pD and 17,20R(OH)2pD are noncalcemic and exhibit antifibrotic activity. J Invest Dermatol (2011) 1.08
A deletion causing spontaneous fracture identified from a candidate region of mouse Chromosome 14. Mamm Genome (2005) 1.08
DNA microarrays: their use and misuse. Microcirculation (2002) 1.04
In vivo and in vitro evidence that the high osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is intrinsic to bone cells. Bone (2004) 1.03
The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton. J Biol Chem (2011) 1.02
Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice. Endocrinology (2010) 1.02
High-resolution whole-genome haplotyping using limited seed data. Nat Methods (2013) 1.01
Genetic increase in serum insulin-like growth factor-I (IGF-I) in C3H/HeJ compared with C57BL/6J mice is associated with increased transcription from the IGF-I exon 2 promoter. Endocrinology (2006) 1.00
Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice. J Bone Miner Res (2003) 0.99
Genetic effects on bone mechanotransduction in congenic mice harboring bone size and strength quantitative trait loci. J Bone Miner Res (2007) 0.97
DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice. J Biol Chem (2012) 0.97
A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis. J Endocrinol (2009) 0.97
Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but nov is dispensable for skeletal homeostasis. Endocrinology (2009) 0.97
Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse. Genomics (2009) 0.96
Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer. Mol Cancer (2010) 0.95
Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. J Biol Chem (2010) 0.94
Evaluation of gene expression profiling in a mouse model of L-gulonolactone oxidase gene deficiency. Genet Mol Biol (2007) 0.92
Quantitative trait loci that determine mouse tibial nanoindentation properties in an F2 population derived from C57BL/6J x C3H/HeJ. Calcif Tissue Int (2007) 0.92
Allelic differences in a quantitative trait locus affecting insulin-like growth factor-I impact skeletal acquisition and body composition. Pediatr Nephrol (2004) 0.91
Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/6J. Funct Integr Genomics (2002) 0.89
Chromosomal regions harboring genes for the work to femur failure in mice. Funct Integr Genomics (2002) 0.89
Clinical utility of microarrays: current status, existing challenges and future outlook. Curr Genomics (2008) 0.89
miRNA biogenesis enzyme Drosha is required for vascular smooth muscle cell survival. PLoS One (2013) 0.89
Casein kinase 2 regulates in vivo bone formation through its interaction with bone morphogenetic protein receptor type Ia. Bone (2011) 0.88
A Line 1 insertion in the Factor IX gene segregates with mild hemophilia B in dogs. Mamm Genome (2003) 0.88
Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background. J Bone Miner Res (2005) 0.88
LH analog and dietary isoflavones support ovarian granulosa cell tumor development in a spontaneous mouse model. Endocr Relat Cancer (2007) 0.87
A single nucleotide mutation in Nppc is associated with a long bone abnormality in lbab mice. BMC Genet (2007) 0.86
Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice. Funct Integr Genomics (2002) 0.86
Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer. Bone (2012) 0.86
Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C. Genet Mol Biol (2011) 0.85
Genome-wide gene expression profiles in antioxidant pathways and their potential sex differences and connections to vitamin C in mice. Int J Mol Sci (2013) 0.84
Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density. Bone (2012) 0.84
Congenic mice provide evidence for a genetic locus that modulates spontaneous arthritis caused by deficiency of IL-1RA. PLoS One (2013) 0.84
Study designs of randomized controlled trials not based on Chinese medicine theory are improper. Chin Med (2009) 0.84
Genetic and molecular basis of quantitative trait loci of arthritis in rat: genes and polymorphisms. J Immunol (2008) 0.84
Dual effects of IL-1 overactivity on the immune system in a mouse model of arthritis due to deficiency of IL-1 receptor antagonist. J Genet Genomics (2013) 0.83
IGF-I secretion by prostate carcinoma cells does not alter tumor-bone cell interactions in vitro or in vivo. Prostate (2006) 0.83
An essential role for the association of CD47 to SHPS-1 in skeletal remodeling. J Bone Miner Res (2011) 0.83
Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice. J Genet (2010) 0.83
Distal Chr 4 harbors a genetic locus (Gct1) fundamental for spontaneous ovarian granulosa cell tumorigenesis in a mouse model. Cancer Res (2005) 0.82
Genetic and Molecular Basis of QTL of Diabetes in Mouse: Genes and Polymorphisms. Curr Genomics (2008) 0.82
Oral cancer: enduring characteristics and emerging trends. J Tenn Dent Assoc (2011) 0.81
High-resolution genetic map of X-linked juvenile-type granulosa cell tumor susceptibility genes in mouse. Cancer Res (2003) 0.81
Altered plasma membrane dynamics of bone morphogenetic protein receptor type Ia in a low bone mass mouse model. Bone (2011) 0.81
Analysis of candidate genes of spontaneous arthritis in mice deficient for interleukin-1 receptor antagonist. Genes Genet Syst (2012) 0.80
Chromosomal inversion discovered in C3H/HeJ mice. Genomics (2005) 0.80
A novel animal model for bone metastasis in human lung cancer. Oncol Lett (2012) 0.80
Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3h/HeJ inbred strains of mice. (2001). J Bone Miner Res (2005) 0.79
Fine map of the Gct1 spontaneous ovarian granulosa cell tumor locus. Mamm Genome (2012) 0.79
Effects of carbonic anhydrase VIII deficiency on cerebellar gene expression profiles in the wdl mouse. Neurosci Lett (2006) 0.78
Oral cancer: enduring characteristics and emerging trends. J Mich Dent Assoc (2012) 0.78
Bone morphogenetic protein receptor type Ia localization causes increased BMP2 signaling in mice exhibiting increased peak bone mass phenotype. J Cell Physiol (2012) 0.78
Anakinra as an interleukin 1 receptor antagonist, complicated genetics and molecular impacts--from the point of view of mouse genomics. Int Immunopharmacol (2012) 0.78
A deletion mutation in Slc12a6 is associated with neuromuscular disease in gaxp mice. Genomics (2008) 0.77
Genomic dissection and prioritizing of candidate genes of QTL for regulating spontaneous arthritis on chromosome 1 in mice deficient for interleukin-1 receptor antagonist. J Genet (2012) 0.77
c-Myb regulates cell cycle-dependent expression of Erbin: an implication for a novel function of Erbin. PLoS One (2012) 0.77
Erbin, a negative regulator in diverse signal pathways. Curr Protein Pept Sci (2010) 0.77
Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: epigenetics and epistasis at work for an ovarian phenotype. Epigenetics (2013) 0.76
An insertion of intracisternal A-particle retrotransposon in a novel member of the phosphoglycerate mutase family in the lew allele of mutant mice. Genes Genet Syst (2009) 0.76
Effects of growth hormone transgene expression on vertebrae in a mouse model of osteogenesis imperfecta. Spine (Phila Pa 1976) (2005) 0.76
Ramucirumab in metastatic renal cell carcinoma: the sex, race, and age issues. Cancer (2014) 0.75
ENU induced single mutation locus on chr 16 leads to high-frequency hearing loss in mice. Genes Genet Syst (2009) 0.75
Identification of immunomodulatory signatures induced by american ginseng in murine immune cells. Evid Based Complement Alternat Med (2013) 0.75
Insulin-like growth factor-1 increases bone calcium accumulation only during rapid growth in female rats. J Nutr (2011) 0.75
Different coexpressions of arthritis-relevant genes between different body organs and different brain regions in the normal mouse population. Gene (2012) 0.75