Published in Chemphyschem on August 25, 2008
Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods (2010) 2.37
Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature (2014) 2.21
Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain. J Cereb Blood Flow Metab (2012) 2.08
Dendritic phosphorescent probes for oxygen imaging in biological systems. ACS Appl Mater Interfaces (2009) 2.01
Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels. Nat Med (2011) 1.65
"Overshoot" of O₂ is required to maintain baseline tissue oxygenation at locations distal to blood vessels. J Neurosci (2011) 1.44
Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression. Appl Opt (2009) 1.41
Frontiers in optical imaging of cerebral blood flow and metabolism. J Cereb Blood Flow Metab (2012) 1.36
Indicators for optical oxygen sensors. Bioanal Rev (2012) 1.34
Two new "protected" oxyphors for biological oximetry: properties and application in tumor imaging. Anal Chem (2011) 1.32
Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy. Opt Express (2009) 1.30
Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease. J Control Release (2010) 1.16
Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nat Commun (2014) 1.12
Design of Metalloporphyrin-Based Dendritic Nanoprobes for Two-Photon Microscopy of Oxygen. J Porphyr Phthalocyanines (2008) 1.10
Microvascular oxygen tension and flow measurements in rodent cerebral cortex during baseline conditions and functional activation. J Cereb Blood Flow Metab (2010) 1.09
Microimaging of oxygen concentration near live photosynthetic cells by electron spin resonance. Biophys J (2010) 1.05
Two-photon absorbing nanocrystal sensors for ratiometric detection of oxygen. J Am Chem Soc (2009) 1.05
Quantifying the microvascular origin of BOLD-fMRI from first principles with two-photon microscopy and an oxygen-sensitive nanoprobe. J Neurosci (2015) 1.03
Optical probes and techniques for O2 measurement in live cells and tissue. Cell Mol Life Sci (2012) 1.02
New biotechnological and nanomedicine strategies for treatment of lysosomal storage disorders. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.01
Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1. J Control Release (2011) 1.01
Ru-porphyrin protein scaffolds for sensing O2. J Am Chem Soc (2010) 0.99
Transport of nanocarriers across gastrointestinal epithelial cells by a new transcellular route induced by targeting ICAM-1. J Control Release (2012) 0.97
Phosphorescent platinum(II) and palladium(II) complexes with azatetrabenzoporphyrins-new red laser diode-compatible indicators for optical oxygen sensing. ACS Appl Mater Interfaces (2010) 0.94
Two-photon microscopy of oxygen: polymersomes as probe carrier vehicles. J Phys Chem B (2010) 0.93
Frequency Multiplexed In Vivo Multiphoton Phosphorescence Lifetime Microscopy. Nat Photonics (2012) 0.92
Two-photon antenna-core oxygen probe with enhanced performance. Anal Chem (2014) 0.92
Two-photon oxygen sensing with quantum dot-porphyrin conjugates. Inorg Chem (2013) 0.91
Strategies for delivery of therapeutics into the central nervous system for treatment of lysosomal storage disorders. Drug Deliv Transl Res (2012) 0.89
Phosphorescent nanoparticles for quantitative measurements of oxygen profiles in vitro and in vivo. Biomaterials (2012) 0.89
FRET excited ratiometric oxygen sensing in living tissue. J Neurosci Methods (2013) 0.88
Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5). Biophys J (2010) 0.87
Evaluation of phototoxicity of dendritic porphyrin-based phosphorescent oxygen probes: an in vitro study. Photochem Photobiol Sci (2011) 0.86
High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime. Sci Rep (2015) 0.85
Three-dimensional mapping of oxygen tension in cortical arterioles before and after occlusion. Biomed Opt Express (2013) 0.84
Highly non-planar dendritic porphyrin for pH sensing: observation of porphyrin monocation. Inorg Chem (2010) 0.83
Mapping oxygen concentration in the awake mouse brain. Elife (2016) 0.83
Modeling of Cerebral Oxygen Transport Based on In vivo Microscopic Imaging of Microvascular Network Structure, Blood Flow, and Oxygenation. Front Comput Neurosci (2016) 0.82
Ratiometric Molecular Probes Based on Dual Emission of a Blue Fluorescent Coumarin and a Red Phosphorescent Cationic Iridium(III) Complex for Intracellular Oxygen Sensing. Sensors (Basel) (2015) 0.81
Multimodal optical imaging system for in vivo investigation of cerebral oxygen delivery and energy metabolism. Biomed Opt Express (2015) 0.81
Cerebral blood oxygenation measurement based on oxygen-dependent quenching of phosphorescence. J Vis Exp (2011) 0.81
Generation of phosphorescent triplet states via photoinduced electron transfer: energy and electron transfer dynamics in Pt porphyrin-Rhodamine B dyads. J Phys Chem A (2012) 0.81
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Philos Trans R Soc Lond B Biol Sci (2016) 0.80
Synthesis of phosphorescent asymmetrically π-extended porphyrins for two-photon applications. J Org Chem (2014) 0.80
Measurement of Local Partial Pressure of Oxygen in the Brain Tissue under Normoxia and Epilepsy with Phosphorescence Lifetime Microscopy. PLoS One (2015) 0.79
Single cell responses to spatially controlled photosensitized production of extracellular singlet oxygen. Photochem Photobiol (2011) 0.79
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors. J Am Chem Soc (2015) 0.79
High-resolution in vivo optical imaging of stroke injury and repair. Brain Res (2015) 0.78
Long-wavelength analyte-sensitive luminescent probes and optical (bio)sensors. Methods Appl Fluoresc (2015) 0.78
Nanoscale Metal-Organic Frameworks for Ratiometric Oxygen Sensing in Live Cells. J Am Chem Soc (2016) 0.77
Multifunctional Phosphorescent Conjugated Polymer Dots for Hypoxia Imaging and Photodynamic Therapy of Cancer Cells. Adv Sci (Weinh) (2015) 0.77
Bright, "Clickable" Porphyrins for the Visualization of Oxygenation under Ambient Light. Angew Chem Int Ed Engl (2015) 0.76
Quantitating intracellular oxygen tension in vivo by phosphorescence lifetime measurement. Sci Rep (2015) 0.76
Spatial landscape of oxygen in and around microvasculature during epileptic events. Neurophotonics (2017) 0.75
Two-photon microscopy measurement of cerebral metabolic rate of oxygen using periarteriolar oxygen concentration gradients. Neurophotonics (2016) 0.75
Validation and optimization of hypercapnic-calibrated fMRI from oxygen-sensitive two-photon microscopy. Philos Trans R Soc Lond B Biol Sci (2016) 0.75
Flexible digital signal processing architecture for narrowband and spread-spectrum lock-in detection in multiphoton microscopy and time-resolved spectroscopy. Rev Sci Instrum (2015) 0.75
Oxygen maps in the brain. Nat Methods (2010) 0.75
Exceptional Oxygen Sensing Properties of New Blue Light-Excitable Highly Luminescent Europium(III) and Gadolinium(III) Complexes. Adv Funct Mater (2014) 0.75
Fluorescence lifetime microscopy of NADH distinguishes alterations in cerebral metabolism in vivo. Biomed Opt Express (2017) 0.75
Two-photon laser scanning fluorescence microscopy. Science (1990) 43.55
Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol (1986) 10.92
Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science (1977) 8.17
An optical method for measurement of dioxygen concentration based upon quenching of phosphorescence. J Biol Chem (1987) 3.46
Single-neuron activity and tissue oxygenation in the cerebral cortex. Science (2003) 2.96
Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue. Science (1988) 2.92
Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration. Proc Natl Acad Sci U S A (2002) 2.62
A real-time ratiometric method for the determination of molecular oxygen inside living cells using sol-gel-based spherical optical nanosensors with applications to rat C6 glioma. Anal Chem (2001) 2.48
A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. J Cell Sci (2003) 2.34
Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle. J Appl Physiol (1985) (2006) 1.99
Real-time measurements of dissolved oxygen inside live cells by organically modified silicate fluorescent nanosensors. Anal Chem (2004) 1.97
The measurement of oxygen in vivo using EPR techniques. Phys Med Biol (1998) 1.97
Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5. Methods Enzymol (2002) 1.94
Intracellular trafficking of nonviral vectors. Gene Ther (2005) 1.78
ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs. Blood (2004) 1.58
Oxygen tension imaging in the mouse retina. Ann Biomed Eng (2003) 1.58
Phosphorescent oxygen sensor with dendritic protection and two-photon absorbing antenna. J Am Chem Soc (2005) 1.49
Spare the rod and spoil the eye. Br J Ophthalmol (2005) 1.28
Energy and electron transfer in enhanced two-photon-absorbing systems with triplet cores. J Phys Chem A (2007) 1.14
Singlet oxygen generation via two-photon excited FRET. J Am Chem Soc (2004) 1.13
Oxygen distribution and vascular injury in the mouse eye measured by phosphorescence-lifetime imaging. Appl Opt (2005) 1.13
PO2 profiles near arterioles and tissue oxygen consumption in rat mesentery. Am J Physiol Heart Circ Physiol (2007) 1.09
Phosphorescence quenching method for measurement of intracellular PO2 in isolated skeletal muscle fibers. J Appl Physiol (1985) (1999) 1.09
Oxygen diffusion and mitochondrial respiration in neuroblastoma cells. Am J Physiol (1989) 1.03
Arylamide dendrimers with flexible linkers via haloacyl halide method. Org Lett (2005) 1.01
Dynamic Quenching of Porphyrin Triplet States by Two-Photon Absorbing Dyes: Towards Two-Photon-Enhanced Oxygen Nanosensors. J Photochem Photobiol A Chem (2008) 0.98
Quantitative determination of localized tissue oxygen concentration in vivo by two-photon excitation phosphorescence lifetime measurements. J Appl Physiol (1985) (2004) 0.95
Ratiometric oxygen sensing: detection of dual-emission ratio through a single emission filter. Analyst (2000) 0.89
Attenuating electron-transfer rates via dendrimer encapsulation: the case of metal tris(bipyridine) core dendrimers. Langmuir (2006) 0.88
Two-photon singlet oxygen microscopy: the challenges of working with single cells. Photochem Photobiol (2007) 0.83
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci U S A (2008) 16.54
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies. J Virol (2005) 15.61
Diversity considerations in HIV-1 vaccine selection. Science (2002) 9.60
Sexual behavior of HIV discordant couples after HIV counseling and testing. AIDS (2003) 8.05
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature (2013) 5.35
Free access to Landsat imagery. Science (2008) 4.75
Wide-field subdiffraction imaging by accumulated binding of diffusing probes. Proc Natl Acad Sci U S A (2006) 4.33
Hybrid origin of SIV in chimpanzees. Science (2003) 3.75
Molecular epidemiology of human immunodeficiency virus type 1 transmission in a heterosexual cohort of discordant couples in Zambia. J Virol (2002) 3.58
Predictors of incomplete adherence, virologic failure, and antiviral drug resistance among HIV-infected adults receiving antiretroviral therapy in Tanzania. Clin Infect Dis (2007) 3.46
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J Immunol (2004) 3.27
A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. Virology (2006) 3.26
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature (2013) 3.00
Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2. PLoS Med (2006) 2.99
Phenotypic properties of transmitted founder HIV-1. Proc Natl Acad Sci U S A (2013) 2.75
High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies. J Virol Methods (2009) 2.75
Ancient co-speciation of simian foamy viruses and primates. Nature (2005) 2.71
Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Mol Ther (2008) 2.69
Effect of reclassification on the incidence of benign and malignant renal tumors. J Urol (2009) 2.67
Two-dimensional infrared spectroscopy of the alanine dipeptide in aqueous solution. J Phys Chem B (2005) 2.52
SIVcpz in wild chimpanzees. Science (2002) 2.45
Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals. J Virol (2011) 2.42
Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods (2010) 2.37
Oxyphor R2 and G2: phosphors for measuring oxygen by oxygen-dependent quenching of phosphorescence. Anal Biochem (2002) 2.36
The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients. Clin Chem (2008) 2.35
Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science (2013) 2.34
Excess of early onset multiple myeloma in endometrial cancer probands and their relatives suggests common susceptibility. Gynecol Oncol (2007) 2.32
In vivo molecular photoacoustic tomography of melanomas targeted by bioconjugated gold nanocages. ACS Nano (2010) 2.29
In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth. J Virol (2009) 2.29
Validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension. Ophthalmology (2006) 2.28
Small bilaterian fossils from 40 to 55 million years before the cambrian. Science (2004) 2.25
Association between donor and recipient TCF7L2 gene polymorphisms and the risk of new-onset diabetes mellitus after liver transplantation in a Han Chinese population. J Hepatol (2012) 2.17
Delaying treatment of ocular hypertension: the ocular hypertension treatment study. Arch Ophthalmol (2010) 2.14
Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. Proc Natl Acad Sci U S A (2005) 2.10
A novel mechanism for vascular insulin resistance in normotensive young SHRs: hypoadiponectinemia and resultant APPL1 downregulation. Hypertension (2013) 2.10
Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nat Med (2002) 2.10
Detection of minor drug-resistant populations by parallel allele-specific sequencing. Nat Methods (2007) 2.09
Chemical exchange 2D IR of hydrogen-bond making and breaking. Proc Natl Acad Sci U S A (2005) 2.09
Type 2 diabetes mellitus: the impact on colorectal adenoma risk in women. Am J Gastroenterol (2006) 2.07
US breast cancer mortality trends in young women according to race. Cancer (2014) 2.07
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape. J Clin Invest (2012) 2.05
Dendritic phosphorescent probes for oxygen imaging in biological systems. ACS Appl Mater Interfaces (2009) 2.01
DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements. Nucleic Acids Res (2013) 2.01
Time to activate lung cancer clinical trials and patient enrollment: a representative comparison study between two academic centers across the atlantic. J Clin Oncol (2010) 2.00
Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle. J Appl Physiol (1985) (2006) 1.99
Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. J Exp Med (2011) 1.97
Aldehyde dehydrogenase 2 ameliorates acute cardiac toxicity of ethanol: role of protein phosphatase and forkhead transcription factor. J Am Coll Cardiol (2009) 1.91
Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7. PLoS Pathog (2012) 1.88
Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type. J Clin Oncol (2007) 1.87
A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys. Proc Natl Acad Sci U S A (2008) 1.80
Retrospective motion correction protocol for high-resolution anatomical MRI. Hum Brain Mapp (2006) 1.80
Microbial biodegradation of polyaromatic hydrocarbons. FEMS Microbiol Rev (2008) 1.80
Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus. Protein Cell (2010) 1.74
Apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor development in a mouse model of ovarian cancer. Proc Natl Acad Sci U S A (2010) 1.71
Effects of pretransplantation treatment with rituximab on outcomes of autologous stem-cell transplantation for non-Hodgkin's lymphoma. J Clin Oncol (2004) 1.70
New simian immunodeficiency virus infecting De Brazza's monkeys (Cercopithecus neglectus): evidence for a cercopithecus monkey virus clade. J Virol (2004) 1.68
Regulation of cardiac fibroblast cellular function by leukemia inhibitory factor. J Mol Cell Cardiol (2002) 1.68
Cervical carcinoma in the elderly: an analysis of patterns of care and outcome. Cancer (2005) 1.68
Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis -induced inflammation and virulence. J Clin Invest (2006) 1.66
Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels. Nat Med (2011) 1.65
Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin. Circulation (2008) 1.64
Two-dimensional infrared spectra of isotopically diluted amyloid fibrils from Abeta40. Proc Natl Acad Sci U S A (2008) 1.63
Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen. J Virol (2006) 1.63
Vasculoprotective effect of insulin in the ischemic/reperfused canine heart: role of Akt-stimulated NO production. Cardiovasc Res (2005) 1.62
Ancestral and consensus envelope immunogens for HIV-1 subtype C. Virology (2006) 1.62
Outcome of patients with ≥70% symptomatic intracranial stenosis after Wingspan stenting. Stroke (2011) 1.62
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects. Science (2009) 1.61
The Gleason score of tumor at the margin in radical prostatectomy is predictive of biochemical recurrence. Am J Surg Pathol (2010) 1.61
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape. PLoS Pathog (2012) 1.61
Two-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase. Proc Natl Acad Sci U S A (2007) 1.61
Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation by the cAMP-PKA pathway. Hepatology (2013) 1.60
Insulin inhibits tumor necrosis factor-alpha induction in myocardial ischemia/reperfusion: role of Akt and endothelial nitric oxide synthase phosphorylation. Crit Care Med (2008) 1.60
Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion. Hepatology (2008) 1.59
Mesh reinforcement of pancreatic transection decreases incidence of pancreatic occlusion failure for left pancreatectomy: a single-blinded, randomized controlled trial. Ann Surg (2012) 1.58
Survivin: a novel player in insulin cardioprotection against myocardial ischemia/reperfusion injury. J Mol Cell Cardiol (2010) 1.58
Trends in stage distribution for patients with non-small cell lung cancer: a National Cancer Database survey. J Thorac Oncol (2010) 1.58
Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. PLoS Pathog (2011) 1.57
Aberrant methylation of the X-linked ribosomal S6 kinase RPS6KA6 (RSK4) in endometrial cancers. Clin Cancer Res (2011) 1.57
A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier. Clin Cancer Res (2004) 1.57
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer. Breast Cancer Res (2011) 1.56
RGD-conjugated dendrimer-modified gold nanorods for in vivo tumor targeting and photothermal therapy. Mol Pharm (2010) 1.55
Relative resistance of HIV-1 founder viruses to control by interferon-alpha. Retrovirology (2013) 1.55
Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium. Arterioscler Thromb Vasc Biol (2012) 1.55
Presentation and stage-specific outcomes of lifelong never-smokers with non-small cell lung cancer (NSCLC). J Thorac Oncol (2007) 1.55
Applications of 2D IR spectroscopy to peptides, proteins, and hydrogen-bond dynamics. J Phys Chem B (2009) 1.54
Advanced drug delivery systems that target the vascular endothelium. Mol Interv (2006) 1.54
Positive margin rates following breast-conserving surgery for stage I-III breast cancer: palpable versus nonpalpable tumors. J Surg Res (2012) 1.53
Predictive value of café au lait macules at initial consultation in the diagnosis of neurofibromatosis type 1. Arch Dermatol (2009) 1.52
Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies. PLoS Comput Biol (2010) 1.51
Predictors of primary breast abscesses and recurrence. World J Surg (2009) 1.51
Toll-like receptor and heme oxygenase-1 signaling in hepatic ischemia/reperfusion injury. Am J Transplant (2005) 1.51
Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins. Virology (2006) 1.51
Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: therapeutic implications for sensitized transplant recipients. J Immunol (2002) 1.50
Phosphorescent oxygen sensor with dendritic protection and two-photon absorbing antenna. J Am Chem Soc (2005) 1.49