Carcinogen-altered genes in rat esophagus positively modulated to normal levels of expression by both black raspberries and phenylethyl isothiocyanate.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMC 3015106)

Published in Cancer Res on August 01, 2008

Authors

Gary D Stoner1, Alan A Dombkowski, Rashmeet K Reen, Daniela Cukovic, Sridevi Salagrama, Li-Shu Wang, John F Lechner

Author Affiliations

1: Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, Ohio 43240, USA. gary.stoner@osumc.edu

Articles citing this

Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer. J Natl Cancer Inst (2011) 1.94

Foodstuffs for preventing cancer: the preclinical and clinical development of berries. Cancer Prev Res (Phila) (2009) 1.41

Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis. Carcinogenesis (2010) 1.04

Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats. Pharm Res (2010) 1.00

Black raspberries inhibit intestinal tumorigenesis in apc1638+/- and Muc2-/- mouse models of colorectal cancer. Cancer Prev Res (Phila) (2010) 0.99

A rapid and sensitive LC-MS/MS method for quantification of four anthocyanins and its application in a clinical pharmacology study of a bioadhesive black raspberry gel. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.94

p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells. Cancer Res (2010) 0.91

Differential in vivo mechanism of chemoprevention of tumor formation in azoxymethane/dextran sodium sulfate mice by PEITC and DBM. Carcinogenesis (2009) 0.91

Different redox states in malignant and nonmalignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol. Antioxid Redox Signal (2009) 0.86

Dietary freeze-dried black raspberry's effect on cellular antioxidant status during reflux-induced esophagitis in rats. Nutrition (2010) 0.78

Chemoprevention of oral cancer by topical application of black raspberries on high at-risk mucosa. Oral Surg Oral Med Oral Pathol Oral Radiol (2014) 0.76

Protective Role of Dietary Berries in Cancer. Antioxidants (Basel) (2016) 0.75

Articles cited by this

The hallmarks of cancer. Cell (2000) 113.05

DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79

The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res (2004) 54.37

Cancer statistics, 2007. CA Cancer J Clin (2007) 53.49

Computational analysis of microarray data. Nat Rev Genet (2001) 18.93

Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet (2007) 4.69

Rosetta error model for gene expression analysis. Bioinformatics (2006) 4.67

Population attributable risks of esophageal and gastric cancers. J Natl Cancer Inst (2003) 3.07

DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation. Nucleic Acids Res (2006) 2.87

Etiology and chemoprevention of esophageal squamous cell carcinoma. Carcinogenesis (2001) 2.27

Inhibition of carcinogenesis by isothiocyanates. Drug Metab Rev (2001) 2.03

PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway. Mol Biol Cell (2007) 1.61

Targeting multiple arms of the apoptotic regulatory machinery. Cancer Res (2007) 1.59

Chemoprevention of esophageal tumorigenesis by dietary administration of lyophilized black raspberries. Cancer Res (2001) 1.56

A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. Oncogene (2002) 1.55

Aberrant expression of RAB1A in human tongue cancer. Br J Cancer (2005) 1.40

Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethylamine carcinogenesis in the rat esophagus. Cancer Res (1991) 1.38

Cancer prevention with freeze-dried berries and berry components. Semin Cancer Biol (2007) 1.36

Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun. Cancer Res (2006) 1.28

The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein. BMC Cancer (2006) 1.25

H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells. J Biol Chem (2005) 1.21

Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation. J Biol Chem (2002) 1.19

Effects of benzyl and phenethyl isothiocyanate on P450s 2A6 and 2A13: potential for chemoprevention in smokers. Carcinogenesis (2005) 1.18

CrkI and CrkII function as key signaling integrators for migration and invasion of cancer cells. Mol Cancer Res (2005) 1.18

Inhibition of N-nitrosobenzylmethylamine-induced esophageal tumorigenesis in rats by ellagic acid. Carcinogenesis (1990) 1.18

Black raspberries inhibit N-nitrosomethylbenzylamine (NMBA)-induced angiogenesis in rat esophagus parallel to the suppression of COX-2 and iNOS. Carcinogenesis (2006) 1.17

Clinical significance of cellular distribution of moesin in patients with oral squamous cell carcinoma. Clin Cancer Res (2004) 1.15

HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1. Oncogene (2004) 1.14

Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway. Cell Mol Life Sci (2005) 1.11

Suppression of prostate carcinoma cell invasion by expression of antisense L-plastin gene. Am J Pathol (1999) 1.09

A diagnostic marker set for invasion, proliferation, and aggressiveness of prolactin pituitary tumors. Endocr Relat Cancer (2007) 1.08

Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C. FASEB J (2000) 1.08

Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels. Cancer Res (2007) 1.07

Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms. Nutr Cancer (2006) 1.06

Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway. Int J Biochem Cell Biol (2006) 1.06

Overexpression of KIAA0101 predicts high stage, early tumor recurrence, and poor prognosis of hepatocellular carcinoma. Clin Cancer Res (2007) 1.05

Chemoprevention of esophageal squamous cell carcinoma. Toxicol Appl Pharmacol (2007) 1.04

Structure and function of the low Mr phosphotyrosine protein phosphatases. Biochim Biophys Acta (1997) 1.02

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis. Curr Biol (2006) 0.96

Identification of alpha-actinin 4 and 67 kDa laminin receptor as stage-specific markers in esophageal cancer via proteomic approaches. Cancer (2007) 0.93

Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1. Cytogenet Genome Res (2004) 0.91

Significance of immunohistochemical over-expression of CD44v6 as an indicator of malignant potential in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol (2004) 0.90

Modulation of N-nitrosomethylbenzylamine metabolism by black raspberries in the esophagus and liver of Fischer 344 rats. Nutr Cancer (2006) 0.90

Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus. Cancer Res (2007) 0.87

Differential regulation of a fibroblast growth factor-binding protein during skin carcinogenesis and wound healing. Neoplasia (2004) 0.85

Association between inducible nitric oxide synthase expression and p53 status in human esophageal squamous cell carcinoma. Oncology (2003) 0.84

Cyclooxygenase-2 expression in squamous cell carcinoma of the esophagus. Dis Esophagus (2006) 0.83

The binding of Mss4 to alpha-integrin subunits regulates matrix metalloproteinase activation and fibronectin remodeling. FASEB J (2006) 0.83

Incidence and effects of Ha-ras codon 12 G-->A transition mutations in preneoplastic lesions induced by N-nitrosomethylbenzylamine in the rat esophagus. Mol Carcinog (2001) 0.82

Characterization of keratins and associated proteins involved in the corneification of crocodilian epidermis. Tissue Cell (2007) 0.77

Articles by these authors

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res (2002) 2.56

Guidelines for incorporating non-perfectly matched oligonucleotides into target-specific hybridization probes for a DNA microarray. Nucleic Acids Res (2004) 2.20

Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia. Blood (2005) 1.51

Laboratory and clinical studies of cancer chemoprevention by antioxidants in berries. Carcinogenesis (2008) 1.47

Anthocyanins in black raspberries prevent esophageal tumors in rats. Cancer Prev Res (Phila) (2009) 1.41

Cancer prevention with freeze-dried berries and berry components. Semin Cancer Biol (2007) 1.36

Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D. J Biomech (2009) 1.31

Liver-specific hepatocyte nuclear factor-4alpha deficiency: greater impact on gene expression in male than in female mouse liver. Mol Endocrinol (2008) 1.30

RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia. Blood (2009) 1.22

Global gene expression profiling unveils S100A8/A9 as candidate markers in H-ras-mediated human breast epithelial cell invasion. Mol Cancer Res (2008) 1.17

Profiling DNA methylomes from microarray to genome-scale sequencing. Technol Cancer Res Treat (2010) 1.17

Intrinsic sex differences in the early growth hormone responsiveness of sex-specific genes in mouse liver. Mol Endocrinol (2010) 1.05

Chemoprevention of esophageal squamous cell carcinoma. Toxicol Appl Pharmacol (2007) 1.04

Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis. Carcinogenesis (2010) 1.04

The mouse and human Ah receptor differ in recognition of LXXLL motifs. Arch Biochem Biophys (2008) 1.03

Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats. Pharm Res (2010) 1.00

Black raspberries inhibit intestinal tumorigenesis in apc1638+/- and Muc2-/- mouse models of colorectal cancer. Cancer Prev Res (Phila) (2010) 0.99

Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity. Arch Biochem Biophys (2005) 0.97

Cross-species comparisons of transcriptomic alterations in human and rat primary hepatocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci (2012) 0.95

An overview of epigenetics and chemoprevention. FEBS Lett (2010) 0.92

Effects of a black raspberry diet on gene expression in the rat esophagus. Nutr Cancer (2008) 0.91

High throughput assembly of spatially controlled 3D cell clusters on a micro/nanoplatform. Lab Chip (2010) 0.91

Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway. Free Radic Biol Med (2010) 0.89

Intestinal epithelial cells in vitro. Stem Cells Dev (2010) 0.89

Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells. Anticancer Res (2010) 0.88

Drinking water with red beetroot food color antagonizes esophageal carcinogenesis in N-nitrosomethylbenzylamine-treated rats. J Med Food (2010) 0.87

Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus. Cancer Res (2007) 0.87

Molecular mechanisms of (-)-gossypol-induced apoptosis in human prostate cancer cells. Anticancer Res (2006) 0.87

Black raspberry components inhibit proliferation, induce apoptosis, and modulate gene expression in rat esophageal epithelial cells. Nutr Cancer (2009) 0.87

Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus. Int J Biochem Mol Biol (2012) 0.86

Keratinocyte growth factor (KGF) induces tamoxifen (Tam) resistance in human breast cancer MCF-7 cells. Anticancer Res (2006) 0.84

Secretome analysis of microarray data reveals extracellular events associated with proliferative potential in a cell line model of breast disease. Cancer Lett (2005) 0.83

Using disulfide bond engineering to study conformational changes in the beta'260-309 coiled-coil region of Escherichia coli RNA polymerase during sigma(70) binding. J Bacteriol (2002) 0.82

Black raspberries protectively regulate methylation of Wnt pathway genes in precancerous colon tissue. Cancer Prev Res (Phila) (2013) 0.82

(-)-Gossypol reduces invasiveness in metastatic prostate cancer cells. Anticancer Res (2009) 0.82

Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells. Int J Mol Med (2010) 0.82

Vacuum-assisted cell seeding in a microwell cell culture system. Anal Chem (2010) 0.82

Mechanistic basis for the chemopreventive effects of black raspberries at a late stage of rat esophageal carcinogenesis. Mol Carcinog (2011) 0.81

Modulation of multidrug resistance gene expression in human breast cancer cells by (-)-gossypol-enriched cottonseed oil. Anticancer Res (2007) 0.81

Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles. Carcinogenesis (2015) 0.80

Augmented annotation and orthologue analysis for Oryctolagus cuniculus: Better Bunny. BMC Bioinformatics (2012) 0.80

Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia. PLoS One (2013) 0.80

Effects of serum on (-)-gossypol-suppressed growth in human prostate cancer cells. Anticancer Res (2006) 0.80

Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patients. Nutr Cancer (2012) 0.80

Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice. J Biol Chem (2010) 0.80

Chemoprevention of esophageal squamous cell carcinoma with berries. Top Curr Chem (2013) 0.79

Primary cultured human breast epithelial cells up-regulate protein disulfide isomerase in response to zeranol. Anticancer Res (2007) 0.79

Intraoperative contrast-enhanced ultrasound in traumatic brain surgery. Clin Imaging (2013) 0.79

Arterial pO₂ stimulates intimal hyperplasia and serum stimulates inward eutrophic remodeling in porcine saphenous veins cultured ex vivo. Biomech Model Mechanobiol (2010) 0.79

Construction and characterization of a t-PA mutant for use in ATTEMPTS: a drug delivery system for achieving targeted thrombolysis. J Control Release (2005) 0.78

Micro/nanoscale technologies for the development of hormone-expressing islet-like cell clusters. Biomed Microdevices (2012) 0.78

Effect of keratinocyte growth factor on cell viability in primary cultured human prostate cancer stromal cells. J Steroid Biochem Mol Biol (2006) 0.78

Pharmacokinetics of protocatechuic acid in mouse and its quantification in human plasma using LC-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.77

A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy. PLoS One (2011) 0.76

Yeast IME2 functions early in meiosis upstream of cell cycle-regulated SBF and MBF targets. PLoS One (2012) 0.76

Transcriptional profiling of the age-related response to genotoxic stress points to differential DNA damage response with age. Mech Ageing Dev (2009) 0.76

Keratinocyte growth factor (KGF) regulates estrogen receptor-alpha (ER-alpha) expression and cell apoptosis via phosphatidylinositol 3-kinase (PI3K)/Akt pathway in human breast cancer cells. Anticancer Res (2009) 0.76

Transcriptional profiles induced by the Aryl Hydrocarbon Receptor agonists 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran in primary rat hepatocytes. Chemosphere (2011) 0.75

Loss of Free Fatty Acid Receptor 2 enhances colonic adenoma development and reduces the chemopreventive effects of black raspberries in ApcMin/+ mice. Carcinogenesis (2016) 0.75

A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes. Toxicol Sci (2013) 0.75

Aging alters folate homeostasis and DNA damage response in colon. Mech Ageing Dev (2012) 0.75

Decreased MCF-7 breast cancer cell proliferation by serum from a selected line of beef cattle. Anticancer Res (2005) 0.75