Published in Proc Natl Acad Sci U S A on August 06, 2008
A bioartificial renal tubule device embedding human renal stem/progenitor cells. PLoS One (2014) 1.45
Hybrid gel composed of native heart matrix and collagen induces cardiac differentiation of human embryonic stem cells without supplemental growth factors. J Cardiovasc Transl Res (2011) 1.41
Mechanotransduction in the renal tubule. Am J Physiol Renal Physiol (2010) 1.29
Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles. Hypertension (2011) 1.10
TEER measurement techniques for in vitro barrier model systems. J Lab Autom (2015) 1.10
Spatially resolved shear distribution in microfluidic chip for studying force transduction mechanisms in cells. Lab Chip (2009) 1.08
Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells. Proc Natl Acad Sci U S A (2010) 1.00
Intratubular hydrodynamic forces influence tubulointerstitial fibrosis in the kidney. Curr Opin Nephrol Hypertens (2010) 0.99
Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase. Nephron Physiol (2010) 0.97
Albumin handling by renal tubular epithelial cells in a microfluidic bioreactor. Biotechnol Bioeng (2011) 0.95
A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells. Biotechnol Bioeng (2010) 0.95
Culturing pancreatic islets in microfluidic flow enhances morphology of the associated endothelial cells. PLoS One (2011) 0.94
Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia. Proc Natl Acad Sci U S A (2014) 0.94
Tissue-engineered kidney disease models. Adv Drug Deliv Rev (2013) 0.93
Mild electrical stimulation and heat shock ameliorates progressive proteinuria and renal inflammation in mouse model of Alport syndrome. PLoS One (2012) 0.91
Luminal flow modulates H+-ATPase activity in the cortical collecting duct (CCD). Am J Physiol Renal Physiol (2011) 0.89
Epithelial-mesenchymal transition and fibrosis are mutually exclusive reponses in shear-activated proximal tubular epithelial cells. FASEB J (2012) 0.88
Shear-induced volume decrease in MDCK cells. Cell Physiol Biochem (2012) 0.87
An Integrative Review of Mechanotransduction in Endothelial, Epithelial (Renal) and Dendritic Cells (Osteocytes). Cell Mol Bioeng (2011) 0.87
Use of optical tweezers to probe epithelial mechanosensation. J Biomed Opt (2010) 0.85
Interplay between cytoskeletal stresses and cell adaptation under chronic flow. PLoS One (2012) 0.84
Chronic fluid flow is an environmental modifier of renal epithelial function. PLoS One (2011) 0.82
Directed stem cell differentiation by fluid mechanical forces. Antioxid Redox Signal (2011) 0.81
Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturation. J Cell Biol (2015) 0.80
Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers. Lab Chip (2013) 0.80
Mild electrical stimulation at 0.1-ms pulse width induces p53 protein phosphorylation and G2 arrest in human epithelial cells. J Biol Chem (2013) 0.80
Flow stimulated endocytosis in the proximal tubule. Curr Opin Nephrol Hypertens (2015) 0.78
Effects of biomechanical forces on signaling in the cortical collecting duct (CCD). Am J Physiol Renal Physiol (2014) 0.78
Flow is critical for maintaining a protective phenotype in renal proximal tubular cells. Am J Transplant (2013) 0.76
Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance. J Am Soc Nephrol (2014) 0.76
Discerning the role of mechanosensors in regulating proximal tubule function. Am J Physiol Renal Physiol (2015) 0.76
A modular microfluidic bioreactor with improved throughput for evaluation of polarized renal epithelial cells. Biomicrofluidics (2016) 0.75
Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells. PLoS One (2015) 0.75
Flow-induced focal adhesion remodeling mediated by local cytoskeletal stresses and reorganization. Cell Adh Migr (2015) 0.75
Hyperfiltration-Associated Biomechanical Forces in Glomerular Injury and Response: Potential Role for Eicosanoids. Prostaglandins Other Lipid Mediat (2017) 0.75
Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells. Physiol Rep (2017) 0.75
Proximal tubule apical endocytosis is modulated by fluid shear stress via an mTOR-dependent pathway. Mol Biol Cell (2017) 0.75
The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a "bumper-car" model. Proc Natl Acad Sci U S A (2004) 2.05
Epithelial Na(+) channels are regulated by flow. Am J Physiol Renal Physiol (2001) 1.90
The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia. Development (2003) 1.71
A hydrodynamic mechanosensory hypothesis for brush border microvilli. Am J Physiol Renal Physiol (2000) 1.64
Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens. Am J Physiol Renal Physiol (2002) 1.37
Vascular endothelial growth factor induces branching morphogenesis/tubulogenesis in renal epithelial cells in a neuropilin-dependent fashion. Mol Cell Biol (2005) 1.29
Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments. Am J Physiol Renal Physiol (2005) 1.24
Mechanosensory function of microvilli of the kidney proximal tubule. Proc Natl Acad Sci U S A (2004) 1.20
Podocytes are sensitive to fluid shear stress in vitro. Am J Physiol Renal Physiol (2006) 1.19
Balance between tubular flow rate and net fluid reabsorption in the proximal convolution of the rat kidney. I. Dependency of reabsorptive net fluid flux upon proximal tubular surface area at spontaneous variations of filtration rate. Pflugers Arch (1968) 1.19
Mechanical strains induced by tubular flow affect the phenotype of proximal tubular cells. Am J Physiol Renal Physiol (2001) 1.17
Flow-dependent transport in a mathematical model of rat proximal tubule. Am J Physiol Renal Physiol (2007) 1.15
Flow dependence of K+ secretion in cortical distal tubules of the rat. Am J Physiol (1989) 1.11
Regional distribution of N-acetyl-D-galactosamine residues in the glycocalyx of glomerular podocytes. J Cell Biol (1983) 1.04
Luminal flow rate regulates proximal tubule H-HCO3 transporters. Am J Physiol (1992) 0.99
Effect of acute changes in glomerular filtration rate on Na+/H+ exchange in rat renal cortex. J Clin Invest (1992) 0.96
Characterization of renal tubular transport of sodium chloride and water as studied in single nephrons. Am J Med (1963) 0.92
Analysis of Rab protein function in neurotransmitter receptor trafficking at hippocampal synapses. Methods Enzymol (2005) 0.92
Volume regulatory responses of basolateral membrane vesicles from Necturus enterocytes: role of the cytoskeleton. Proc Natl Acad Sci U S A (1999) 0.82
Sequencing of 50 human exomes reveals adaptation to high altitude. Science (2010) 11.27
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. N Engl J Med (2014) 3.57
From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal. Nature (2009) 3.18
Six-helix bundles designed from DNA. Nano Lett (2005) 2.62
A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps. Proc Natl Acad Sci U S A (2006) 2.61
Paranemic crossover DNA: a generalized Holliday structure with applications in nanotechnology. J Am Chem Soc (2004) 2.58
Dishevelled promotes axon differentiation by regulating atypical protein kinase C. Nat Cell Biol (2007) 2.55
Effect of flow and stretch on the [Ca2+]i response of principal and intercalated cells in cortical collecting duct. Am J Physiol Renal Physiol (2003) 2.25
Mechanotransduction and strain amplification in osteocyte cell processes. Proc Natl Acad Sci U S A (2004) 2.16
Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation. Proc Natl Acad Sci U S A (2013) 2.10
The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a "bumper-car" model. Proc Natl Acad Sci U S A (2004) 2.05
Bone marrow stromal cells transduced with human hemangiopoietin gene support hematopoiesis in vitro. Haematologica (2005) 2.03
Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus. J Clin Invest (2004) 2.00
Ultrastructure of the osteocyte process and its pericellular matrix. Anat Rec A Discov Mol Cell Evol Biol (2004) 1.96
Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance. Nat Genet (2013) 1.95
Functional expression of the olfactory signaling system in the kidney. Proc Natl Acad Sci U S A (2009) 1.90
Biomechanics: cell research and applications for the next decade. Ann Biomed Eng (2009) 1.81
In situ measurement of solute transport in the bone lacunar-canalicular system. Proc Natl Acad Sci U S A (2005) 1.68
Renal and intestinal transport defects in Slc26a6-null mice. Am J Physiol Cell Physiol (2004) 1.68
Mechanoregulation of intracellular Ca2+ concentration is attenuated in collecting duct of monocilium-impaired orpk mice. Am J Physiol Renal Physiol (2005) 1.66
Oil and tocopherol content and composition of pumpkin seed oil in 12 cultivars. J Agric Food Chem (2007) 1.65
Transgenic RNAi depletion of claudin-16 and the renal handling of magnesium. J Biol Chem (2007) 1.64
A model for the role of integrins in flow induced mechanotransduction in osteocytes. Proc Natl Acad Sci U S A (2007) 1.61
Angiotensin II increases chloride absorption in the cortical collecting duct in mice through a pendrin-dependent mechanism. Am J Physiol Renal Physiol (2006) 1.59
A mechanistic analysis of the role of microcalcifications in atherosclerotic plaque stability: potential implications for plaque rupture. Am J Physiol Heart Circ Physiol (2012) 1.55
Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis. Am J Physiol Cell Physiol (2013) 1.53
Revised microcalcification hypothesis for fibrous cap rupture in human coronary arteries. Proc Natl Acad Sci U S A (2013) 1.51
Fluid and Solute Transport in Bone: Flow-Induced Mechanotransduction. Annu Rev Fluid Mech (2009) 1.49
Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J Biol Chem (2002) 1.49
Mechanosensation and transduction in osteocytes. Bone (2012) 1.46
The potential mechanisms of reduced incidence of ventricular fibrillation as the presenting rhythm in sudden cardiac arrest. Crit Care Med (2009) 1.44
Improvements of cardiac electrophysiologic stability and ventricular fibrillation threshold in rats with myocardial infarction treated with cardiac stem cells. Crit Care Med (2011) 1.39
Micro-CT based analysis of a new paradigm for vulnerable plaque rupture: cellular microcalcifications in fibrous caps. Mol Cell Biomech (2008) 1.39
Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins. Am J Physiol Renal Physiol (2008) 1.36
Digital microfluidic platform for multiplexing enzyme assays: implications for lysosomal storage disease screening in newborns. Clin Chem (2011) 1.31
Pendrin modulates ENaC function by changing luminal HCO3-. J Am Soc Nephrol (2010) 1.29
Mechanotransduction in the renal tubule. Am J Physiol Renal Physiol (2010) 1.29
Disruption of Myosin 1e promotes podocyte injury. J Am Soc Nephrol (2008) 1.27
Double cohesion in structural DNA nanotechnology. Org Biomol Chem (2006) 1.26
Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair. J Biol Chem (2010) 1.26
Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments. Am J Physiol Renal Physiol (2005) 1.24
Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium. Am J Physiol Renal Physiol (2011) 1.23
NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity. Am J Physiol Renal Physiol (2007) 1.22
Repair mechanisms of bone marrow mesenchymal stem cells in myocardial infarction. J Cell Mol Med (2011) 1.21
Mechanosensory function of microvilli of the kidney proximal tubule. Proc Natl Acad Sci U S A (2004) 1.20
Cellular fluid mechanics and mechanotransduction. Ann Biomed Eng (2005) 1.18
Fluid shear stress remodels expression and function of junctional proteins in cultured bone cells. Am J Physiol Cell Physiol (2002) 1.18
The quality of chest compressions during cardiopulmonary resuscitation overrides importance of timing of defibrillation. Chest (2007) 1.15
Validation of reference genes for gene expression studies in peanut by quantitative real-time RT-PCR. Mol Genet Genomics (2011) 1.15
Flow-dependent transport in a mathematical model of rat proximal tubule. Am J Physiol Renal Physiol (2007) 1.15
New roles for old holes: ion channel function in aquaporin-1. News Physiol Sci (2002) 1.14
Berberine Moderates Glucose and Lipid Metabolism through Multipathway Mechanism. Evid Based Complement Alternat Med (2010) 1.13
Inward rectifier channel, ROMK, is localized to the apical tips of glial-like cells in mouse taste buds. J Comp Neurol (2009) 1.13
Low Na intake suppresses expression of CYP2C23 and arachidonic acid-induced inhibition of ENaC. Am J Physiol Renal Physiol (2006) 1.12
Ultrathin-film growth of para-sexiphenyl (I): submonolayer thin-film growth as a function of the substrate temperature. J Phys Chem B (2008) 1.10
Role of PDZK1 in membrane expression of renal brush border ion exchangers. Proc Natl Acad Sci U S A (2005) 1.08
Evidence of a relationship between infant birth weight and later diabetes and impaired glucose regulation in a Chinese population. Diabetes Care (2007) 1.06
POD1 regulates pollen tube guidance in response to micropylar female signaling and acts in early embryo patterning in Arabidopsis. Plant Cell (2011) 1.05
A mathematical model of rat ascending Henle limb. II. Epithelial function. Am J Physiol Renal Physiol (2009) 1.05
Changing views of the biomechanics of vulnerable plaque rupture: a review. Ann Biomed Eng (2013) 1.03
On bone adaptation due to venous stasis. J Biomech (2003) 1.03
p53-dependent BRCA1 nuclear export controls cellular susceptibility to DNA damage. Cancer Res (2011) 1.03
[Research report of experimental database establishment of digitized virtual Chinese No.1 female]. Di Yi Jun Yi Da Xue Xue Bao (2003) 1.02
Mechanism of osmotic flow in a periodic fiber array. Am J Physiol Heart Circ Physiol (2005) 1.02
A mathematical model of rat ascending Henle limb. III. Tubular function. Am J Physiol Renal Physiol (2009) 1.02
Multiplex newborn screening for Pompe, Fabry, Hunter, Gaucher, and Hurler diseases using a digital microfluidic platform. Clin Chim Acta (2013) 1.01
BRCA1-Ku80 protein interaction enhances end-joining fidelity of chromosomal double-strand breaks in the G1 phase of the cell cycle. J Biol Chem (2013) 1.01
Rapid, single-step assay for Hunter syndrome in dried blood spots using digital microfluidics. Clin Chim Acta (2011) 1.01
Air pollution and autonomic and vascular dysfunction in patients with cardiovascular disease: interactions of systemic inflammation, overweight, and gender. Am J Epidemiol (2012) 1.00
Time series analysis of Japanese encephalitis and weather in Linyi City, China. Int J Public Health (2011) 1.00
Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases. J Med Chem (2004) 1.00
Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells. Proc Natl Acad Sci U S A (2010) 1.00
Bone marrow mesenchymal stem cells for post-myocardial infarction cardiac repair: microRNAs as novel regulators. J Cell Mol Med (2012) 0.99
The explosive growth of small voids in vulnerable cap rupture; cavitation and interfacial debonding. J Biomech (2012) 0.99
Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration. J Neuroimmune Pharmacol (2008) 0.98
Role of PKC and calcium in modulation of effects of angiotensin II on sodium transport in proximal tubule. Am J Physiol Renal Physiol (2003) 0.98
Genomic and proteomic microglial profiling: pathways for neuroprotective inflammatory responses following nerve fragment clearance and activation. J Neurochem (2007) 0.98
A mathematical model of rat ascending Henle limb. I. Cotransporter function. Am J Physiol Renal Physiol (2009) 0.98
Cardiac stem cells and their roles in myocardial infarction. Stem Cell Rev (2013) 0.96
Subcellular proteomics revealed the epithelial-mesenchymal transition phenotype in lung cancer. Proteomics (2011) 0.96
ROMK is required for expression of the 70-pS K channel in the thick ascending limb. Am J Physiol Renal Physiol (2003) 0.96
High-energy defibrillation impairs myocyte contractility and intracellular calcium dynamics. Crit Care Med (2008) 0.96
Novel cassette arrays of integrons in clinical strains of Enterobacteriaceae in China. Int J Antimicrob Agents (2008) 0.96
Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons. Neuro Oncol (2011) 0.95