Increased serum heat-shock protein 70 levels reflect systemic inflammation, oxidative stress and hepatocellular injury in preeclampsia.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMC 2727991)

Published in Cell Stress Chaperones on August 07, 2008

Authors

Attila Molvarec1, János Rigó, Levente Lázár, Krisztián Balogh, Veronika Makó, László Cervenak, Miklós Mézes, Zoltán Prohászka

Author Affiliations

1: 1st Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary. molvarec@freemail.hu

Articles citing this

Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol (2010) 2.04

Serum leptin levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in normal pregnancy and preeclampsia. Reprod Biol Endocrinol (2011) 1.18

Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: a review and comparison to other methods of detection in thoracic aneurysm repair. Cell Stress Chaperones (2010) 1.07

Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies. Cell Stress Chaperones (2009) 1.02

Plasma Hsp72 (HSPA1A) and Hsp27 (HSPB1) expression under heat stress: influence of exercise intensity. Cell Stress Chaperones (2012) 0.98

Increased circulating heat shock protein 70 levels in pregnant asthmatics. Cell Stress Chaperones (2009) 0.95

Serum heat shock protein 70 and oxidized LDL in patients with type 2 diabetes: does sex matter? Cell Stress Chaperones (2010) 0.93

Circulating anti-heat-shock-protein antibodies in normal pregnancy and preeclampsia. Cell Stress Chaperones (2009) 0.87

Nitric oxide and reactive oxygen species in the pathogenesis of preeclampsia. Int J Mol Sci (2015) 0.85

Increased heat shock protein 70 levels in induced sputum and plasma correlate with severity of asthma patients. Cell Stress Chaperones (2011) 0.84

Biomarkers for the management of pre-eclampsia in pregnant women. Indian J Med Res (2013) 0.84

Circulating ficolin-2 and ficolin-3 in normal pregnancy and pre-eclampsia. Clin Exp Immunol (2012) 0.83

High levels of acute phase proteins and soluble 70 kDa heat shock proteins are independent and additive risk factors for mortality in colorectal cancer. Cell Stress Chaperones (2010) 0.83

Appearance of leptin-HSP70 correlation, in type 2 diabetes. Meta Gene (2013) 0.81

Interaction between the inducible 70-kDa heat shock protein and autophagy: effects on fertility and pregnancy. Cell Stress Chaperones (2015) 0.80

Increased circulating heat shock protein 70 (HSPA1A) levels in gestational diabetes mellitus: a pilot study. Cell Stress Chaperones (2015) 0.78

Comparison of hemodynamic, biochemical and hematological parameters of healthy pregnant women in the third trimester of pregnancy and the active labor phase. BMC Pregnancy Childbirth (2011) 0.75

Decreased circulating anandamide levels in preeclampsia. Hypertens Res (2015) 0.75

Circulating heat shock protein mRNA profile in gestational hypertension, pre-eclampsia & foetal growth restriction. Indian J Med Res (2016) 0.75

Trophoblast survival signaling during human placentation requires HSP70 activation of MMP2-mediated HBEGF shedding. Cell Death Differ (2017) 0.75

Elevated serum heat shock protein 70 and liver stiffness reflect hepatic dysfunction and severity in postoperative biliary atresia. Pediatr Surg Int (2017) 0.75

Articles cited by this

Latest advances in understanding preeclampsia. Science (2005) 8.11

HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med (2000) 6.20

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem (2002) 6.16

Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ (2005) 5.96

Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol (1999) 4.74

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. Int Immunol (2000) 4.48

CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin. Immunity (2001) 4.16

Heat shock, stress proteins, chaperones, and proteotoxicity. Cell (1991) 3.96

Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems. Anal Biochem (1966) 3.53

Preeclampsia: recent insights. Hypertension (2005) 2.98

Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins. J Biol Chem (2005) 2.64

Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation (2002) 2.44

Heat shock proteins as regulators of the immune response. Lancet (2003) 2.42

Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes. J Immunol (2006) 2.13

Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release. J Biol Chem (2003) 2.02

Detection of heat shock protein 70 (Hsp70) and anti-Hsp70 antibodies in the serum of normal individuals. Immunol Invest (1998) 1.79

Extracellular hsp70 levels in children with septic shock. Pediatr Crit Care Med (2005) 1.79

Exercise increases serum Hsp72 in humans. Cell Stress Chaperones (2001) 1.69

Hsp70 release from peripheral blood mononuclear cells. Biochem Biophys Res Commun (2004) 1.58

Serum levels of Hsp 72 measured early after trauma correlate with survival. J Trauma (2002) 1.49

A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue. J Immunol (2000) 1.46

Exercise induces hepatosplanchnic release of heat shock protein 72 in humans. J Physiol (2002) 1.45

Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart (2005) 1.38

Extracellular HSP70 binding to surface receptors present on antigen presenting cells and endothelial/epithelial cells. FEBS Lett (2005) 1.34

Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72. J Immunol (2005) 1.26

Stress proteins and initiation of immune response: chaperokine activity of hsp72. Exerc Immunol Rev (2005) 1.24

Immunological aspects of heat-shock proteins-the optimum stress of life. Mol Immunol (2004) 1.23

Elevated levels of circulating heat shock protein 70 (Hsp70) in peripheral and renal vascular disease. Heart Vessels (2000) 1.23

Heat shock protein 70 is a potent activator of the human complement system. Cell Stress Chaperones (2002) 1.20

Plasma levels of heat shock protein 70 in patients with prostate cancer: a potential biomarker for prostate cancer. Clin Prostate Cancer (2004) 1.14

Exercise intensity and duration affect blood soluble HSP72. Int J Sports Med (2005) 1.13

Activation of T cells recognizing an epitope of heat-shock protein 70 can protect against rat adjuvant arthritis. J Immunol (1999) 1.13

Changes in markers of muscle damage, inflammation and HSP70 after an Ironman Triathlon race. Eur J Appl Physiol (2006) 1.11

Heat shock protein 70 in patients with chronic heart failure: relation to disease severity and survival. Int J Cardiol (2004) 1.11

Association of elevated serum heat-shock protein 70 concentration with transient hypertension of pregnancy, preeclampsia and superimposed preeclampsia: a case-control study. J Hum Hypertens (2006) 1.07

The pathogenesis of pre-eclampsia. Gynecol Obstet Fertil (2001) 1.07

Elevated serum heat-shock protein 70 levels in patients with acute infection: use of an optimized enzyme-linked immunosorbent assay. Scand J Immunol (2003) 1.06

A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis. Clin Exp Immunol (1996) 1.04

Changes in serum levels of heat shock protein 70 in preterm delivery and pre-eclampsia. J Obstet Gynaecol Res (2005) 1.03

Circulating heat-shock protein 70 is associated with postoperative infection and organ dysfunction after liver resection. Am J Surg (2004) 0.99

Interaction of serum 70-kDa heat shock protein levels and HspA1B (+1267) gene polymorphism with disease severity in patients with chronic heart failure. Cell Stress Chaperones (2008) 0.96

Effects of heat shock, stannous chloride, and gallium nitrate on the rat inflammatory response. Cell Stress Chaperones (2001) 0.94

Association of increased serum heat shock protein 70 and C-reactive protein concentrations and decreased serum alpha(2)-HS glycoprotein concentration with the syndrome of hemolysis, elevated liver enzymes, and low platelet count. J Reprod Immunol (2006) 0.94

Serum heat shock protein 70 levels are decreased in normal human pregnancy. J Reprod Immunol (2007) 0.92

Folate supplementation reduces serum hsp70 levels in patients with type 2 diabetes. Cell Stress Chaperones (2004) 0.91

Elevated serum 70 kDa heat shock protein level reflects tissue damage and disease severity in the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Eur J Obstet Gynecol Reprod Biol (2008) 0.90

Vitamin E isoform-specific inhibition of the exercise-induced heat shock protein 72 expression in humans. J Appl Physiol (1985) (2005) 0.89

Serum levels of heat shock protein 70 in patients with preeclampsia: a pilot-study. Wien Klin Wochenschr (2002) 0.88

HSP70 is associated with endothelial activation in placental vascular diseases. Mol Med (2008) 0.85

Sickle cell vaso-occlusive crisis induces the release of circulating serum heat shock protein-70. Am J Hematol (2005) 0.83

Presence of cell-free fetal DNA in plasma of women with ectopic pregnancies. Clin Chem (2006) 0.82

Articles by these authors

Similar genetic features and different islet cell autoantibody pattern of latent autoimmune diabetes in adults (LADA) compared with adult-onset type 1 diabetes with rapid progression. Diabetes Care (2003) 2.64

Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state. Am Heart J (2009) 2.37

Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol (2010) 2.04

Relationship of anti-60 kDa heat shock protein and anti-cholesterol antibodies to cardiovascular events. Circulation (2002) 1.65

Adenosine triphosphate concentration of exhaled breath condensate in asthma. Chest (2010) 1.48

Activation of the complement system in normal pregnancy and preeclampsia. Mol Immunol (2010) 1.37

The R1141X loss-of-function mutation of the ABCC6 gene is a strong genetic risk factor for coronary artery disease. Genet Test Mol Biomarkers (2010) 1.31

Increased prevalence of IL-17-producing peripheral blood lymphocytes in pre-eclampsia. Am J Reprod Immunol (2011) 1.25

Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS. Cytometry A (2010) 1.18

Serum leptin levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in normal pregnancy and preeclampsia. Reprod Biol Endocrinol (2011) 1.18

Complement protease MASP-1 activates human endothelial cells: PAR4 activation is a link between complement and endothelial function. J Immunol (2009) 1.13

Effect of formalin, acetone, and RNAlater fixatives on tissue preservation and different size amplicons by real-time PCR from paraffin-embedded tissue. Diagn Mol Pathol (2004) 1.10

Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease. Atherosclerosis (2004) 1.09

Human fetuin/alpha2HS-glycoprotein level as a novel indicator of liver cell function and short-term mortality in patients with liver cirrhosis and liver cancer. Eur J Gastroenterol Hepatol (2002) 1.08

Modified low density lipoproteins differentially bind and activate the C1 complex of complement. Mol Immunol (2006) 1.08

Meta-analysis of gene expression profiles associated with histological classification and survival in 829 ovarian cancer samples. Int J Cancer (2011) 1.06

4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study. Crit Care (2010) 1.05

Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin. Circulation (2002) 1.03

FcRn mediates elongated serum half-life of human IgG in cattle. Int Immunol (2006) 1.03

Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies. Cell Stress Chaperones (2009) 1.02

Relationship between the tumor necrosis factor alpha polymorphism and the serum C-reactive protein levels in inflammatory bowel disease. Immunogenetics (2003) 1.01

Studies on the interactions between C-reactive protein and complement proteins. Immunology (2007) 1.01

Association between estrogen receptor alpha (ESR1) gene polymorphisms and severe preeclampsia. Hypertens Res (2007) 1.01

Circulating angiogenic factors determined by electrochemiluminescence immunoassay in relation to the clinical features and laboratory parameters in women with pre-eclampsia. Hypertens Res (2010) 1.01

Decreased number of FoxP3+ regulatory T cells in preeclampsia. Acta Obstet Gynecol Scand (2008) 0.97

The frequency of peripheral blood CD4+ CD25high FoxP3+ and CD4+ CD25- FoxP3+ regulatory T cells in normal pregnancy and pre-eclampsia. Am J Reprod Immunol (2012) 0.97

Interaction of serum 70-kDa heat shock protein levels and HspA1B (+1267) gene polymorphism with disease severity in patients with chronic heart failure. Cell Stress Chaperones (2008) 0.96

Foetal craniopharyngioma diagnosed by prenatal ultrasonography and confirmed by histopathological examination. Prenat Diagn (2009) 0.96

Single umbilical artery in fetopathological investigations. Pathol Res Pract (2008) 0.96

Paradoxical alteration of acute-phase protein levels in patients with chronic hepatitis C treated with IFN-alpha2b. Int Immunol (2004) 0.95

Increased circulating heat shock protein 70 levels in pregnant asthmatics. Cell Stress Chaperones (2009) 0.95

Serum level of soluble Hsp70 is associated with vascular calcification. Cell Stress Chaperones (2010) 0.95

Genetic polymorphisms of vascular endothelial growth factor in severe pre-eclampsia. Mol Hum Reprod (2006) 0.94

Complement activation in animal and human pregnancies as a model for immunological recognition. Mol Immunol (2011) 0.94

Association of extracellular superoxide dismutase (SOD3) Ala40Thr gene polymorphism with pre-eclampsia complicated by severe fetal growth restriction. Eur J Obstet Gynecol Reprod Biol (2008) 0.93

Association of high serum concentration of the third component of complement (C3) with pre-existing severe coronary artery disease and new vascular events in women. Atherosclerosis (2004) 0.93

Red cell distribution width: a powerful prognostic marker in heart failure. Eur J Heart Fail (2010) 0.93

High rate of early restenosis after carotid eversion endarterectomy in homozygous carriers of the normal mannose-binding lectin genotype. Stroke (2005) 0.92

Serum heat shock protein 70 levels are decreased in normal human pregnancy. J Reprod Immunol (2007) 0.92

Lipid, haemostatic and inflammatory variables in relation to the estrogen receptor alpha (ESR1) PvuII and XbaI gene polymorphisms. Clin Chim Acta (2007) 0.90

Association between tumor necrosis factor (TNF)-alpha G-308A gene polymorphism and preeclampsia complicated by severe fetal growth restriction. Clin Chim Acta (2008) 0.90

The 8.1 ancestral MHC haplotype is associated with delayed onset of colonization in cystic fibrosis. Int Immunol (2006) 0.90

Elevated levels of mitochondrial mortalin and cytosolic HSP70 in blood as risk factors in patients with colorectal cancer. Int J Cancer (2013) 0.90

Elevated serum 70 kDa heat shock protein level reflects tissue damage and disease severity in the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Eur J Obstet Gynecol Reprod Biol (2008) 0.90

The effect of long-term danazol prophylaxis on liver function in hereditary angioedema-a longitudinal study. Eur J Clin Pharmacol (2009) 0.89

Peripheral T(h)1/T(h)2/T(h)17/regulatory T-cell balance in asthmatic pregnancy. Int Immunol (2011) 0.89

Antibodies against the human heat shock protein hsp70 in patients with severe coronary artery disease. Immunol Invest (2002) 0.89

Comparative analysis of linear antibody epitopes on human and mycobacterial 60-kDa heat shock proteins using samples of healthy blood donors. Int Immunol (2003) 0.89

Strong complement activation after acute ischemic stroke is associated with unfavorable outcomes. Atherosclerosis (2008) 0.89

Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke. J Neuroinflammation (2011) 0.88

Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3. J Immunol (2012) 0.88

Exhaled nitric oxide in pregnant healthy and asthmatic women. J Asthma (2009) 0.88

Human serum fetuin A/alpha2HS-glycoprotein level is associated with long-term survival in patients with alcoholic liver cirrhosis, comparison with the Child-Pugh and MELD scores. BMC Gastroenterol (2007) 0.88

Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. Thromb Haemost (2009) 0.88

Opposite changes in carotid versus aortic stiffness during healthy human pregnancy. Clin Sci (Lond) (2005) 0.88

Positive predictive value of prenatal ultrasonography confirmed by post-mortem investigations. Eur J Obstet Gynecol Reprod Biol (2011) 0.88

MBL and C1q compete for interaction with human endothelial cells. Mol Immunol (2006) 0.88

Estrogen receptor alpha (ESR1) PvuII and XbaI gene polymorphisms in ischemic stroke in a Hungarian population. Clin Chim Acta (2007) 0.87

Relationship of circulating cell-free DNA levels to cell-free fetal DNA levels, clinical characteristics and laboratory parameters in preeclampsia. BMC Med Genet (2009) 0.87

Circulating anti-heat-shock-protein antibodies in normal pregnancy and preeclampsia. Cell Stress Chaperones (2009) 0.87

Serum heat shock protein 70 levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in women with preeclampsia. Clin Chim Acta (2011) 0.87

Differences in the genetic background of latent autoimmune diabetes in adults (LADA) and type 1 diabetes mellitus. Immunol Lett (2002) 0.86

Family history of early-onset cardiovascular disorders is associated with a higher risk of severe preeclampsia. Eur J Obstet Gynecol Reprod Biol (2006) 0.86

Traitors of the immune system-enhancing antibodies in HIV infection: their possible implication in HIV vaccine development. Vaccine (2008) 0.86

Genetic basis of tobacco smoking: strong association of a specific major histocompatibility complex haplotype on chromosome 6 with smoking behavior. Int Immunol (2004) 0.86

Chaperone-related immune dysfunction: an emergent property of distorted chaperone networks. Trends Immunol (2005) 0.86

Functional analysis of the mannose-binding lectin complement pathway in normal pregnancy and preeclampsia. J Reprod Immunol (2010) 0.86

Anti-mutated citrullinated vimentin (anti-MCV) and anti-65 kDa heat shock protein (anti-hsp65): new biomarkers in ankylosing spondylitis. Joint Bone Spine (2011) 0.85

Novel anti-cholesterol monoclonal immunoglobulin G antibodies as probes and potential modulators of membrane raft-dependent immune functions. J Lipid Res (2006) 0.85