Published in J Biol Chem on April 07, 2003
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells. Cancer Res (2005) 2.72
Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. FASEB J (2010) 1.90
Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Ritossa. Cell Stress Chaperones (2010) 1.69
Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii. Eukaryot Cell (2006) 1.64
Heat shock proteins: linking danger and pathogen recognition. Med Microbiol Immunol (2007) 1.45
Hsp70 and its molecular role in nervous system diseases. Biochem Res Int (2011) 1.44
Membranes: a meeting point for lipids, proteins and therapies. J Cell Mol Med (2008) 1.37
Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3. PLoS One (2008) 1.30
In vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoforms. PLoS Genet (2009) 1.29
Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70. Anesthesiology (2008) 1.29
Hsp60 is actively secreted by human tumor cells. PLoS One (2010) 1.27
αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. PLoS One (2010) 1.27
Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72. J Immunol (2005) 1.26
4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo. J Invest Dermatol (2005) 1.20
Endoplasmic reticulum chaperone protein GRP-78 mediates endocytosis of dentin matrix protein 1. J Biol Chem (2008) 1.15
Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells. FASEB J (2009) 1.15
Increased serum heat-shock protein 70 levels reflect systemic inflammation, oxidative stress and hepatocellular injury in preeclampsia. Cell Stress Chaperones (2008) 1.13
AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells. J Biol Chem (2010) 1.09
Exercise induces the release of heat shock protein 72 from the human brain in vivo. Cell Stress Chaperones (2004) 1.07
Release of heat shock protein 70 and the effects of extracellular heat shock protein 70 on the production of IL-10 in fibroblast-like synoviocytes. Cell Stress Chaperones (2008) 1.05
Neuron specific metabolic adaptations following multi-day exposures to oxygen glucose deprivation. Biochim Biophys Acta (2010) 1.02
Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies. Cell Stress Chaperones (2009) 1.02
Innate immunity and cardiomyocytes in ischemic heart disease. Life Sci (2014) 1.02
Serum heat shock protein 70 level as a biomarker of exceptional longevity. Mech Ageing Dev (2006) 1.01
Spike protein VP4 assembly with maturing rotavirus requires a postendoplasmic reticulum event in polarized caco-2 cells. J Virol (2004) 0.98
In vivo imaging of CT26 mouse tumours by using cmHsp70.1 monoclonal antibody. J Cell Mol Med (2011) 0.97
Leczyme: a new candidate drug for cancer therapy. Biomed Res Int (2014) 0.97
Chaperone proteins and brain tumors: potential targets and possible therapeutics. Neuro Oncol (2005) 0.97
Heat stress causes spatially-distinct membrane re-modelling in K562 leukemia cells. PLoS One (2011) 0.96
The human HSP70 family of chaperones: where do we stand? Cell Stress Chaperones (2016) 0.95
Heat shock cognate protein 70 contributes to Brucella invasion into trophoblast giant cells that cause infectious abortion. BMC Microbiol (2008) 0.94
Heat and exercise acclimation increases intracellular levels of Hsp72 and inhibits exercise-induced increase in intracellular and plasma Hsp72 in humans. Cell Stress Chaperones (2010) 0.93
Stress chaperone GRP-78 functions in mineralized matrix formation. J Biol Chem (2011) 0.93
Hsp70 negatively controls rotavirus protein bioavailability in caco-2 cells infected by the rotavirus RF strain. J Virol (2006) 0.93
Human resting extracellular heat shock protein 72 concentration decreases during the initial adaptation to exercise in a hot, humid environment. Cell Stress Chaperones (2006) 0.92
Integral and peripheral association of proteins and protein complexes with Yersinia pestis inner and outer membranes. Proteome Sci (2009) 0.92
Major role of HSP70 as a paracrine inducer of cytokine production in human oxidized LDL treated macrophages. Atherosclerosis (2005) 0.90
Heat shock proteins form part of a danger signal cascade in response to lipopolysaccharide and GroEL. Clin Exp Immunol (2006) 0.90
Sphingolipids regulate the yeast high-osmolarity glycerol response pathway. Mol Cell Biol (2012) 0.89
The effect of 15 consecutive days of heat-exercise acclimation on heat shock protein 70. Cell Stress Chaperones (2008) 0.89
Rescue of atypical protein kinase C in epithelia by the cytoskeleton and Hsp70 family chaperones. J Cell Sci (2009) 0.89
Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells. PLoS One (2009) 0.88
Clinical correlation of circulating heat shock protein 70 in acute leukemia. Leuk Res (2009) 0.88
The role of endogenously produced extracellular hsp72 in mononuclear cell reprogramming. Shock (2008) 0.87
Plant and animal homeodomains use convergent mechanisms for intercellular transfer. EMBO Rep (2005) 0.87
The complex function of hsp70 in metastatic cancer. Cancers (Basel) (2013) 0.87
Exosomes in prostate cancer: putting together the pieces of a puzzle. Cancers (Basel) (2013) 0.85
Salivary Hsp72 does not track exercise stress and caffeine-stimulated plasma Hsp72 responses in humans. Cell Stress Chaperones (2010) 0.85
Cell wall polysaccharide synthases are located in detergent-resistant membrane microdomains in oomycetes. Appl Environ Microbiol (2009) 0.85
Induction, modification and accumulation of HSP70s in the rat liver after acute exercise: early and late responses. J Physiol (2004) 0.85
Serum level of soluble 70-kD heat shock protein is associated with high mortality in patients with colorectal cancer without distant metastasis. Cell Stress Chaperones (2009) 0.85
Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma. Neuro Oncol (2013) 0.84
Genetic modification of the Salmonella membrane physical state alters the pattern of heat shock response. J Bacteriol (2010) 0.83
Lysosomal rerouting of Hsp70 trafficking as a potential immune activating tool for targeting melanoma. Curr Pharm Des (2013) 0.83
Multifunctional ECM proteins in bone and teeth. Exp Cell Res (2014) 0.82
Monoclonal antibody to novel cell surface epitope on Hsc70 promotes morphogenesis of bile ducts in newborn rat liver. Cell Stress Chaperones (2009) 0.82
Laser vaccine adjuvants. History, progress, and potential. Hum Vaccin Immunother (2014) 0.82
Interaction of heat shock protein 70 with membranes depends on the lipid environment. Cell Stress Chaperones (2014) 0.82
Tumor imaging and targeting potential of an Hsp70-derived 14-mer peptide. PLoS One (2014) 0.80
Exploring prion protein biology in flies: genetics and beyond. Prion (2010) 0.80
Proteomic and systems biology analysis of monocytes exposed to securinine, a GABA(A) receptor antagonist and immune adjuvant. PLoS One (2012) 0.80
IL-10 is significantly involved in HSP70-regulation of experimental subretinal fibrosis. PLoS One (2013) 0.80
Participation of ezrin in bacterial uptake by trophoblast giant cells. Reprod Biol Endocrinol (2009) 0.79
Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells. PLoS One (2013) 0.78
Nonsteroidal anti-inflammatory drugs differentially affect the heat shock response in cultured spinal cord cells. Cell Stress Chaperones (2005) 0.78
Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme). Oncol Rep (2013) 0.78
Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicol Appl Pharmacol (2011) 0.78
Role of Exogenous Hsp72 on Liver Dysfunction during Sepsis. Biomed Res Int (2015) 0.78
Expression of the protein chaperone, clusterin, in spinal cord cells constitutively and following cellular stress, and upregulation by treatment with Hsp90 inhibitor. Cell Stress Chaperones (2013) 0.77
Biochemical characterization of the interaction between HspA1A and phospholipids. Cell Stress Chaperones (2015) 0.77
Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid. Free Radic Biol Med (2013) 0.77
Membrane heat shock protein 70: a theranostic target for cancer therapy. Philos Trans R Soc Lond B Biol Sci (2018) 0.77
Extracellular cell stress (heat shock) proteins-immune responses and disease: an overview. Philos Trans R Soc Lond B Biol Sci (2018) 0.76
Evidence of a Cell Surface Role for Hsp90 Complex Proteins Mediating Neuroblast Migration in the Subventricular Zone. Front Cell Neurosci (2017) 0.76
Sulfatide-Hsp70 interaction promotes Hsp70 clustering and stabilizes binding to unfolded protein. Biomolecules (2015) 0.76
β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice. Front Cell Neurosci (2016) 0.76
Effects of cytarabine on activation of human T cells - cytarabine has concentration-dependent effects that are modulated both by valproic acid and all-trans retinoic acid. BMC Pharmacol Toxicol (2015) 0.76
Sialidase NEU3 dynamically associates to different membrane domains specifically modifying their ganglioside pattern and triggering Akt phosphorylation. PLoS One (2014) 0.76
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas. Blood (2012) 0.76
Bacterial Hsp70 (DnaK) and mammalian Hsp70 interact differently with lipid membranes. Cell Stress Chaperones (2016) 0.76
Exercise, heat shock proteins and insulin resistance. Philos Trans R Soc Lond B Biol Sci (2018) 0.76
Salivary extracellular heat shock protein 70 (eHSP70) levels increase after 59 min of intense exercise and correlate with resting salivary secretory immunoglobulin A (SIgA) levels at rest. Cell Stress Chaperones (2015) 0.75
Acute exercise boosts cell proliferation and the heat shock response in lymphocytes: correlation with cytokine production and extracellular-to-intracellular HSP70 ratio. Cell Stress Chaperones (2017) 0.75
Membrane-enriched proteome changes and prion protein expression during neural differentiation and in neuroblastoma cells. BMC Genomics (2017) 0.75
Heat shock proteins as modulators and therapeutic targets of chronic disease: an integrated perspective. Philos Trans R Soc Lond B Biol Sci (2018) 0.75
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A (2008) 14.18
Proof of principle for transfusion of in vitro-generated red blood cells. Blood (2011) 3.01
Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases. Gut (2012) 2.17
Raft-mediated trafficking of apical resident proteins occurs in both direct and transcytotic pathways in polarized hepatic cells: role of distinct lipid microdomains. Mol Biol Cell (2003) 1.46
Sera from patients with Crohn's disease break bacterial lipopolysaccharide tolerance of human intestinal epithelial cells via MD-2 activity. Innate Immun (2010) 1.43
Circulating secretory phospholipase A2 activity predicts recurrent events in patients with severe acute coronary syndromes. J Am Coll Cardiol (2005) 1.28
Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex. J Am Soc Nephrol (2005) 1.15
Detergents induce raft-like domains budding and fission from giant unilamellar heterogeneous vesicles: a direct microscopy observation. Chem Phys Lipids (2005) 1.14
Rafts promote assembly and atypical targeting of a nonenveloped virus, rotavirus, in Caco-2 cells. J Virol (2002) 1.14
Non-metabolic membrane tubulation and permeability induced by bioactive peptides. PLoS One (2007) 1.07
Cyclooxygenase-2 and its role in colorectal cancer development. Virchows Arch (2004) 1.07
Vimentin affects localization and activity of sodium-glucose cotransporter SGLT1 in membrane rafts. J Cell Sci (2002) 1.05
Galectin-4-regulated delivery of glycoproteins to the brush border membrane of enterocyte-like cells. Traffic (2009) 1.05
Rotavirus spike protein VP4 binds to and remodels actin bundles of the epithelial brush border into actin bodies. J Virol (2006) 0.99
Spike protein VP4 assembly with maturing rotavirus requires a postendoplasmic reticulum event in polarized caco-2 cells. J Virol (2004) 0.98
Basolateral internalization of GPI-anchored proteins occurs via a clathrin-independent flotillin-dependent pathway in polarized hepatic cells. Mol Biol Cell (2009) 0.98
Expression of nonstructural rotavirus protein NSP4 mimics Ca2+ homeostasis changes induced by rotavirus infection in cultured cells. J Virol (2008) 0.95
Current smoking differentially affects blood mononuclear cells from patients with Crohn's disease and ulcerative colitis: relevance to its adverse role in the disease. Inflamm Bowel Dis (2011) 0.95
Hsp70 negatively controls rotavirus protein bioavailability in caco-2 cells infected by the rotavirus RF strain. J Virol (2006) 0.93
Glycan-modifying bacteria-derived soluble factors from Bacteroides thetaiotaomicron and Lactobacillus casei inhibit rotavirus infection in human intestinal cells. Microbes Infect (2011) 0.91
Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition. Clin Pharmacol Ther (2003) 0.90
Interactions of rotavirus VP4 spike protein with the endosomal protein Rab5 and the prenylated Rab acceptor PRA1. J Virol (2003) 0.89
MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells. Life Sci (2007) 0.88
Cytoplasmic phospholipase A2 expression in human colon adenocarcinoma is correlated with cyclooxygenase-2 expression and contributes to prostaglandin E2 production. Cancer Lett (2006) 0.87
Host-pathogens cross-talk. Indigenous bacteria and probiotics also play the game. Biol Cell (2003) 0.87
Differential solubilization of inner plasma membrane leaflet components by Lubrol WX and Triton X-100. Biochim Biophys Acta (2007) 0.86
The homeodomain derived peptide Penetratin induces curvature of fluid membrane domains. PLoS One (2008) 0.86
Cytoplasmic phospholipase A2 alpha overexpression in stromal cells is correlated with angiogenesis in human colorectal cancer. Mod Pathol (2005) 0.86
Bile acid profiling in human biological samples: comparison of extraction procedures and application to normal and cholestatic patients. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.86
1-benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside blocks the apical biosynthetic pathway in polarized HT-29 cells. J Biol Chem (2003) 0.85
Role for actin in the polarized release of rotavirus. J Virol (2007) 0.85
Cytosolic phospholipase A2-p11 interaction controls arachidonic acid release as a function of epithelial cell confluence. Biochem J (2004) 0.84
COX-2, inflammatory secreted PLA2, and cytoplasmic PLA2 protein expression in small bowel adenocarcinomas compared with colorectal adenocarcinomas. Mod Pathol (2003) 0.84
Surface proteome analysis of a natural isolate of Lactococcus lactis reveals the presence of pili able to bind human intestinal epithelial cells. Mol Cell Proteomics (2013) 0.84
Microbial-host interactions specifically control the glycosylation pattern in intestinal mouse mucosa. Histochem Cell Biol (2002) 0.83
Heterogeneity of Raft-type membrane microdomains associated with VP4, the rotavirus spike protein, in Caco-2 and MA 104 cells. J Virol (2006) 0.83
[Transduction peptides: structural-functional analyses in model membranes]. J Soc Biol (2006) 0.82
Regulation of colon cancer cell proliferation and migration by MD-2 activity. Innate Immun (2010) 0.81
Mucinous colon carcinomas with microsatellite instability have a lower microvessel density and lower vascular endothelial growth factor expression. Virchows Arch (2002) 0.80
Indigenous microbes and their soluble factors differentially modulate intestinal glycosylation steps in vivo. Use of a "lectin assay" to survey in vivo glycosylation changes. Histochem Cell Biol (2005) 0.80
HDLs induce raft domain vanishing in heterogeneous giant vesicles. Chem Phys Lipids (2004) 0.80
Modulation of the phase heterogeneity of aminoglycerophospholipid mixtures by sphingomyelin and monovalent cations: maintenance of the lamellar arrangement in the biological membranes. Eur Biophys J (2004) 0.79
Abnormal transbilayer distribution of phospholipids in red blood cell membranes in schizophrenia. Psychiatry Res (2009) 0.78
Metabolic energy-independent mechanism of internalization for the cell penetrating peptide penetratin. Int J Biochem Cell Biol (2012) 0.78
Tubular structures in heterogeneous membranes induced by the cell penetrating peptide penetratin. Commun Integr Biol (2009) 0.78
Effects of dairy products on heterocyclic aromatic amine-induced rat colon carcinogenesis. Carcinogenesis (2002) 0.78
Distinct behaviour of the homeodomain derived cell penetrating peptide penetratin in interaction with different phospholipids. PLoS One (2010) 0.77
Lipid domain separation, bilayer thickening and pearling induced by the cell penetrating peptide penetratin. Biochim Biophys Acta (2010) 0.77
Arsenic trioxide reduces 2,4,6-trinitrobenzene sulfonic acid-induced murine colitis via nuclear factor-κB down-regulation and caspase-3 activation. Innate Immun (2010) 0.77
Enteric nervous system impairment in gastroschisis. Eur J Pediatr Surg (2012) 0.76
Liquid-liquid immiscibility under non-equilibrium conditions in a model membrane: an X-ray synchrotron study. Colloids Surf B Biointerfaces (2009) 0.76
Differential detergent resistance of the apical and basolateral NPPases: relationship with polarized targeting. J Cell Sci (2007) 0.76
Rotavirus-like particles: a novel nanocarrier for the gut. J Biomed Biotechnol (2010) 0.76
[Mechanisms of sorting and transport of proteins to tw membrane domains of epithelial cells]. J Soc Biol (2003) 0.76
Secretory phospholipase A(2) activity and release kinetics of vascular tissue remodelling biomarkers after coronary artery bypass grafting with and without cardiopulmonary bypass. Clin Chem Lab Med (2007) 0.75
High-resolution mass spectrometry and partial de novo sequencing constitute a useful approach for determining the profile of chemokine secretion following the stimulation of human intestinal epithelial cells. Rapid Commun Mass Spectrom (2013) 0.75
Hyperthermia assists survival of astrocytes from oxidative-mediated necrotic cell death. Cell Mol Biol (Noisy-le-grand) (2002) 0.75