Published in PLoS One on August 13, 2008
Adult hippocampal neurogenesis and its role in Alzheimer's disease. Mol Neurodegener (2011) 2.03
HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J Neuroimmune Pharmacol (2010) 1.87
Bridging animal and human models of exercise-induced brain plasticity. Trends Cogn Sci (2013) 1.79
Neurogenesis and Alzheimer's disease: at the crossroads. Exp Neurol (2009) 1.54
Neurodegeneration and the neurovascular unit. Nat Med (2010) 1.37
Adverse stress, hippocampal networks, and Alzheimer's disease. Neuromolecular Med (2009) 1.34
Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2010) 1.27
All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis. Curr Top Behav Neurosci (2013) 1.25
Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease. ASN Neuro (2011) 1.18
Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease. Nature (2016) 1.14
APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation. PLoS One (2010) 1.11
Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer's disease. J Anat (2012) 1.07
Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice. PLoS One (2010) 1.03
Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications. Ageing Res Rev (2008) 1.02
Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain. Am J Pathol (2011) 1.02
Neuroprotective effects of 17β-estradiol rely on estrogen receptor membrane initiated signals. Front Physiol (2012) 1.01
Neurosteroids as regenerative agents in the brain: therapeutic implications. Nat Rev Endocrinol (2013) 0.99
Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair. Trends Neurosci (2012) 0.99
Adult human neurogenesis: from microscopy to magnetic resonance imaging. Front Neurosci (2011) 0.98
Hippocampal neurogenesis levels predict WATERMAZE search strategies in the aging brain. PLoS One (2013) 0.97
DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes. Nucleic Acids Res (2014) 0.96
Adult neurogenesis in neurodegenerative diseases. Cold Spring Harb Perspect Biol (2015) 0.96
Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. Neurobiol Aging (2011) 0.96
Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease. Cell Death Dis (2010) 0.96
Roles for oestrogen receptor β in adult brain function. J Neuroendocrinol (2012) 0.94
Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes. Mol Cell Neurosci (2012) 0.92
Neural stem cells: mechanisms and modeling. Protein Cell (2012) 0.91
Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission? Mol Neurodegener (2011) 0.90
Neurogenesis in Alzheimer's disease. J Anat (2011) 0.90
All in the Family: How the APPs Regulate Neurogenesis. Front Neurosci (2012) 0.90
Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders. Front Cell Neurosci (2014) 0.90
Why looking at the whole hippocampus is not enough-a critical role for anteroposterior axis, subfield and activation analyses to enhance predictive value of hippocampal changes for Alzheimer's disease diagnosis. Front Cell Neurosci (2014) 0.89
Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? Biomed Res Int (2014) 0.87
The endogenous regenerative capacity of the damaged newborn brain: boosting neurogenesis with mesenchymal stem cell treatment. J Cereb Blood Flow Metab (2013) 0.87
Prolonged running, not fluoxetine treatment, increases neurogenesis, but does not alter neuropathology, in the 3xTg mouse model of Alzheimer's disease. Curr Top Behav Neurosci (2013) 0.86
Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1-42 on neural progenitor cell proliferation. Neurobiol Aging (2013) 0.86
Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease. Mol Neurodegener (2010) 0.86
Astrocytes and glutamate homoeostasis in Alzheimer's disease: a decrease in glutamine synthetase, but not in glutamate transporter-1, in the prefrontal cortex. ASN Neuro (2013) 0.85
Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease. Front Endocrinol (Lausanne) (2012) 0.84
Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse. Mol Psychiatry (2014) 0.83
G-protein-coupled receptors in adult neurogenesis. Pharmacol Rev (2012) 0.83
Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease. Exp Eye Res (2014) 0.83
Tau protein and adult hippocampal neurogenesis. Front Neurosci (2012) 0.83
Hypothalamic subependymal niche: a novel site of the adult neurogenesis. Cell Mol Neurobiol (2014) 0.82
Calcium and neurogenesis in Alzheimer's disease. Front Neurosci (2010) 0.82
Aging and neurogenesis, a lesion from Alzheimer's disease. Aging Dis (2010) 0.82
Hippocampal neurogenesis: Learning to remember. Prog Neurobiol (2016) 0.82
Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms. Front Neurosci (2016) 0.81
Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels. Alzheimers Res Ther (2014) 0.81
Deletion of GIRK2 Subunit of GIRK Channels Alters the 5-HT1A Receptor-Mediated Signaling and Results in a Depression-Resistant Behavior. Int J Neuropsychopharmacol (2015) 0.81
Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics. Int J Alzheimers Dis (2012) 0.81
Age-related proteomic changes in the subventricular zone and their association with neural stem/progenitor cell proliferation. J Neurosci Res (2012) 0.81
Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance. PLoS One (2012) 0.80
Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2. Cell Death Dis (2013) 0.80
Intranasal delivery of plasma and platelet growth factors using PRGF-Endoret system enhances neurogenesis in a mouse model of Alzheimer's disease. PLoS One (2013) 0.80
Human tau expression reduces adult neurogenesis in a mouse model of tauopathy. Neurobiol Aging (2015) 0.79
Mesenchymal Stem Cells Preserve Working Memory in the 3xTg-AD Mouse Model of Alzheimer's Disease. Int J Mol Sci (2016) 0.79
Role of Liver X Receptor in AD Pathophysiology. PLoS One (2015) 0.79
Designer Self-Assemble Peptides Maximize the Therapeutic Benefits of Neural Stem Cell Transplantation for Alzheimer's Disease via Enhancing Neuron Differentiation and Paracrine Action. Mol Neurobiol (2015) 0.78
Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease. J Alzheimers Dis (2011) 0.78
Cognitive deficits and disruption of neurogenesis in a mouse model of apolipoprotein E4 domain interaction. J Biol Chem (2013) 0.78
Therapeutic application of neural stem cells and adult neurogenesis for neurodegenerative disorders: regeneration and beyond. Eur J Neurodegener Dis (2015) 0.77
Effect of Astragaloside IV on Neural Stem Cell Transplantation in Alzheimer's Disease Rat Models. Evid Based Complement Alternat Med (2016) 0.77
Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease. Stem Cell Reports (2017) 0.76
Physiological and pathological roles of the γ-secretase complex. Brain Res Bull (2016) 0.76
Barriers to developing a valid rodent model of Alzheimer's disease: from behavioral analysis to etiological mechanisms. Front Neurosci (2015) 0.75
Impaired APP activity and altered Tau splicing in embryonic stem cell-derived astrocytes obtained from an APPsw transgenic minipig. Dis Model Mech (2015) 0.75
Modulation of the subthalamic nucleus activity by serotonergic agents and fluoxetine administration. Psychopharmacology (Berl) (2013) 0.75
Physiological, pathological, and engineered cell identity reprogramming in the central nervous system. Wiley Interdiscip Rev Dev Biol (2016) 0.75
Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function. Int Neurourol J (2016) 0.75
Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's Disease. J Alzheimers Dis (2016) 0.75
Cognitive Intervention As an Early Non-pharmacological Strategy in Alzheimer's Disease: A Translational Perspective. Front Aging Neurosci (2016) 0.75
Chronic Progressive Neurodegeneration in a Transgenic Mouse Model of Prion Disease. Front Neurosci (2016) 0.75
Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease. Sci Rep (2016) 0.75
Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease. Sci Rep (2016) 0.75
Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease. Front Neurosci (2017) 0.75
Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (1991) 49.03
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem (1981) 38.93
Mechanisms and functional implications of adult neurogenesis. Cell (2008) 14.50
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron (2003) 14.03
Functional neurogenesis in the adult hippocampus. Nature (2002) 11.17
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol (1965) 9.18
Neurogenesis in the adult is involved in the formation of trace memories. Nature (2001) 8.13
GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature (2005) 7.04
Regional dissociations within the hippocampus--memory and anxiety. Neurosci Biobehav Rev (2004) 4.44
Adult neurogenesis: from precursors to network and physiology. Physiol Rev (2005) 4.25
Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochem Res (2000) 3.84
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol Aging (2003) 3.83
Experience-induced neurogenesis in the senescent dentate gyrus. J Neurosci (1998) 3.71
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2006) 3.61
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci (1997) 3.61
Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci U S A (2003) 3.52
Multipotent progenitor cells in the adult dentate gyrus. J Neurobiol (1998) 3.15
Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat. J Neurosci (1999) 3.01
Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain. Neuron (1993) 2.97
Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces. Neuron (2001) 2.92
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem (2002) 2.45
Neurogenesis in the adult brain: death of a dogma. Nat Rev Neurosci (2000) 2.44
Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways. Hippocampus (2006) 2.43
Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice. Proc Natl Acad Sci U S A (2004) 2.20
Adult neurogenesis and neural stem cells of the central nervous system in mammals. J Neurosci Res (2002) 2.02
Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone. Development (2004) 2.00
Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. J Neurosci (2007) 2.00
Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J Comp Neurol (2006) 1.96
Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease. Biol Psychiatry (2006) 1.66
Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress. Neuroscience (2004) 1.66
Investigation of glial cells in semithin sections. 3. Transformation of subependymal cells into glial cells, as shown by radioautography after 3 H-thymidine injection into the lateral ventricle of the brain of young rats. J Comp Neurol (1973) 1.64
Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease. Neuromolecular Med (2002) 1.63
Adult neurogenesis in mammals: an identity crisis. J Neurosci (2002) 1.61
Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Res (2008) 1.56
Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus. Neurobiol Dis (2006) 1.54
Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain. Brain Res Dev Brain Res (2002) 1.48
Gonadal hormone modulation of hippocampal neurogenesis in the adult. Hippocampus (2006) 1.48
New nerve cells for the adult brain. Sci Am (1999) 1.47
Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis. Neuroscience (2004) 1.38
Changes in extracellular space size and geometry in APP23 transgenic mice: a model of Alzheimer's disease. Proc Natl Acad Sci U S A (2005) 1.35
Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. J Neurosci (2007) 1.34
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiol Dis (2007) 1.30
Gender and endogenous levels of estradiol do not influence adult hippocampal neurogenesis in mice. Hippocampus (2007) 1.30
Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice. Neurobiol Dis (2002) 1.24
Endogenous estrogen levels and Alzheimer's disease among postmenopausal women. Neurology (2000) 1.18
Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation. Am J Pathol (2005) 1.17
The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta Neuropathol (2002) 1.10
Sex, hormones, and Alzheimer's disease. J Gerontol A Biol Sci Med Sci (2005) 1.07
Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4. Mol Ther (2008) 1.02
Pregnenolone sulfate enhances neurogenesis and PSA-NCAM in young and aged hippocampus. Neurobiol Aging (2005) 0.93
Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis. Alzheimer Dis Assoc Disord (2005) 0.83
Alzheimer's disease: a multisystem disorder. Res Publ Assoc Res Nerv Ment Dis (1986) 0.82
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron (2003) 14.03
Alzheimer's disease. N Engl J Med (2010) 13.13
Physiology of microglia. Physiol Rev (2011) 6.99
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron (2005) 6.20
Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci (2007) 5.72
Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron (2004) 5.52
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol Aging (2003) 3.83
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci (2005) 3.18
Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. J Biol Chem (2010) 3.16
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A (2009) 2.96
Purinergic signalling in the nervous system: an overview. Trends Neurosci (2008) 2.86
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. J Clin Invest (2004) 2.80
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nat Neurosci (2010) 2.79
Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. J Biol Chem (2005) 2.56
Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose. Neuron (2006) 2.53
Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms. J Neurosci (2007) 2.47
Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. J Neurosci (2006) 2.45
Microglia: new roles for the synaptic stripper. Neuron (2013) 2.44
Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles. J Biol Chem (2006) 2.33
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice. J Neurosci (2006) 2.32
Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice. J Neurosci (2008) 2.21
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol (2009) 2.16
Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline. J Neurosci (2010) 2.12
M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron (2006) 2.07
Artifact versus reality--how astrocytes contribute to synaptic events. Glia (2012) 2.02
Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. J Neurosci (2007) 2.00
A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP. Proc Natl Acad Sci U S A (2002) 1.97
Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability. J Neurosci (2004) 1.92
Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ. J Neurosci (2005) 1.91
Glial cells in (patho)physiology. J Neurochem (2012) 1.89
Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J Neurosci (2008) 1.88
SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Cell Biol (2008) 1.84
Linking calcium to Abeta and Alzheimer's disease. Neuron (2008) 1.82
Alzheimer's disease: Abeta, tau and synaptic dysfunction. Trends Mol Med (2005) 1.78
Inflammation induces tau pathology in inclusion body myositis model via glycogen synthase kinase-3beta. Ann Neurol (2008) 1.71
Proliferating resident microglia after focal cerebral ischaemia in mice. J Cereb Blood Flow Metab (2007) 1.71
NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J Neurosci (2006) 1.69
Vesicular release of ATP at central synapses. Pflugers Arch (2006) 1.69
Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders. Neurobiol Aging (2005) 1.68
Intraluminal calcium as a primary regulator of endoplasmic reticulum function. Cell Calcium (2005) 1.68
A dynamic relationship between intracellular and extracellular pools of Abeta. Am J Pathol (2006) 1.66
Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease. Glia (2010) 1.66
Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. J Immunol (2009) 1.66
Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. J Neuroinflammation (2005) 1.64
Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. PLoS One (2011) 1.62
Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiol Dis (2009) 1.60
Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice. Am J Pathol (2012) 1.60
Abeta inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiol Aging (2007) 1.58
Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Res (2008) 1.56
Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. J Med Chem (2004) 1.55
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice. Am J Pathol (2008) 1.55
Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability. J Biol Chem (2009) 1.53
Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease. J Neurochem (2005) 1.52
Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium (2005) 1.52
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Res (2008) 1.51
Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proc Natl Acad Sci U S A (2005) 1.51
Glucose-sensing neurons of the hypothalamus. Philos Trans R Soc Lond B Biol Sci (2005) 1.50
Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology. J Neurosci (2008) 1.49
Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels. J Neurosci (2007) 1.47
Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities. J Neurosci (2011) 1.47
Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity. Brain Pathol (2011) 1.46
Neural stem cells improve memory in an inducible mouse model of neuronal loss. J Neurosci (2007) 1.46
Brain inflammation is induced by co-morbidities and risk factors for stroke. Brain Behav Immun (2011) 1.44
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling. Aging Cell (2012) 1.43
Congo red and thioflavin-T analogs detect Abeta oligomers. J Neurochem (2007) 1.43
Astroglial excitability and gliotransmission: an appraisal of Ca2+ as a signalling route. ASN Neuro (2012) 1.40
Mitochondria and calcium in health and disease. Cell Calcium (2008) 1.39
Platelet interleukin-1alpha drives cerebrovascular inflammation. Blood (2010) 1.38
CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2010) 1.37
The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging. Aging Cell (2007) 1.36
Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model. J Immunol (2011) 1.36
Relevance of transgenic mouse models to human Alzheimer disease. J Biol Chem (2008) 1.36
Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens. Eukaryot Cell (2005) 1.36
Glial calcium and diseases of the nervous system. Cell Calcium (2009) 1.34
Ca2+ regulation and gene expression in normal brain aging. Trends Neurosci (2004) 1.32
Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model. J Neurosci (2013) 1.32
Calcium signalling: past, present and future. Cell Calcium (2005) 1.31
Neuroglia: the 150 years after. Trends Neurosci (2008) 1.31
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiol Dis (2007) 1.30
Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia. J Clin Invest (2004) 1.29
Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology. Biol Psychiatry (2013) 1.28
Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. J Neurochem (2006) 1.27
Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system. Cell Calcium (2007) 1.26
Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice. Biol Psychiatry (2009) 1.25
Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis. Bioorg Med Chem Lett (2003) 1.25