High-throughput screens for fluorescent dye discovery.

Apparent activity in high-throughput screening: origins of compound-dependent assay interference. Curr Opin Chem Biol (2010) 1.76

Visualizing chemical structure-subcellular localization relationships using fluorescent small molecules as probes of cellular transport. J Cheminform (2013) 0.80

Chemical address tags of fluorescent bioimaging probes. Cytometry A (2010) 0.77

Identification of cancer cell-line origins using fluorescence image-based phenomic screening. PLoS One (2012) 0.77

Amyloid histology stain for rapid bacterial endospore imaging. J Clin Microbiol (2011) 0.75

Selective imaging of mitochondrial surfaces with novel fluorescent probes. Chembiochem (2011) 0.75

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell (2006) 18.81

CellProfiler: free, versatile software for automated biological image analysis. Biotechniques (2007) 14.71

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software. Bioinformatics (2011) 12.98

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning. Proc Natl Acad Sci U S A (2009) 5.15

In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication. Nat Genet (2006) 5.14

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell (2011) 4.70

Long-range directional movement of an interphase chromosome site. Curr Biol (2006) 3.96

Visualization of image data from cells to organisms. Nat Methods (2010) 3.66

The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proc Natl Acad Sci U S A (2006) 3.64

CellProfiler Analyst: data exploration and analysis software for complex image-based screens. BMC Bioinformatics (2008) 2.99

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nat Methods (2006) 2.94

Biological imaging software tools. Nat Methods (2012) 2.91

RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells. Nat Methods (2004) 2.72

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. Nature (2013) 2.46

Microarrays of lentiviruses for gene function screens in immortalized and primary cells. Nat Methods (2006) 2.18

Genetic architecture of Hsp90-dependent drug resistance. Eukaryot Cell (2006) 2.09

An algorithm-based topographical biomaterials library to instruct cell fate. Proc Natl Acad Sci U S A (2011) 1.99

High-throughput screen for novel antimicrobials using a whole animal infection model. ACS Chem Biol (2009) 1.99

Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J Clin Invest (2011) 1.96

A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host Microbe (2013) 1.95

In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation. Mol Cell Biol (2005) 1.60

Cell microarrays and RNA interference chip away at gene function. Nat Genet (2005) 1.56

Annotated high-throughput microscopy image sets for validation. Nat Methods (2012) 1.53

Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat Chem Biol (2013) 1.49

An image analysis toolbox for high-throughput C. elegans assays. Nat Methods (2012) 1.48

Introduction to the quantitative analysis of two-dimensional fluorescence microscopy images for cell-based screening. PLoS Comput Biol (2009) 1.45

Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell (2012) 1.26

Ultrasome: efficient aberration caller for copy number studies of ultra-high resolution. Bioinformatics (2009) 1.21

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol (2010) 1.19

Multiplex cytological profiling assay to measure diverse cellular states. PLoS One (2013) 1.19

Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment. J Biomol Screen (2013) 1.19

Abnormalities in mitochondrial structure in cells from patients with bipolar disorder. Am J Pathol (2010) 1.19

RESOLVING CLUSTERED WORMS VIA PROBABILISTIC SHAPE MODELS. Proc IEEE Int Symp Biomed Imaging (2010) 1.13

Using CellProfiler for automatic identification and measurement of biological objects in images. Curr Protoc Mol Biol (2008) 1.12

Workflow and metrics for image quality control in large-scale high-content screens. J Biomol Screen (2011) 1.08

Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells. Mol Endocrinol (2005) 1.08

Screening cellular feature measurements for image-based assay development. J Biomol Screen (2010) 0.98

An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor. PLoS One (2009) 0.97

Visualization of parameter space for image analysis. IEEE Trans Vis Comput Graph (2011) 0.93

A chemical screen probing the relationship between mitochondrial content and cell size. PLoS One (2012) 0.91

Software opens the door to quantitative imaging. Nat Methods (2007) 0.91

Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling. Genome Res (2011) 0.87

Using CellProfiler for Automatic Identification and Measurement of Biological Objects in Images. Curr Protoc Mol Biol (2015) 0.87

Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model. J Clin Invest (2015) 0.81

Automated image-based assay for evaluation of HIV neutralization and cell-to-cell fusion inhibition. BMC Infect Dis (2014) 0.75