Published in Biochim Biophys Acta on July 30, 2008
Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. Cell Metab (2011) 2.41
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. Dev Cell (2013) 2.39
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The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets. J Cell Biol (2011) 1.51
A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assembly. PLoS Pathog (2011) 1.41
Rab proteins and the compartmentalization of the endosomal system. Cold Spring Harb Perspect Biol (2014) 1.40
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Remodeling of lipid droplets during lipolysis and growth in adipocytes. J Biol Chem (2012) 1.29
Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine. J Biol Chem (2011) 1.27
Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease. J Lipid Res (2013) 1.25
Hydrophobic and basic domains target proteins to lipid droplets. Traffic (2009) 1.22
Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens. PLoS One (2010) 1.19
Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones. Nutr Metab (Lond) (2010) 1.18
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Proteomic study and marker protein identification of Caenorhabditis elegans lipid droplets. Mol Cell Proteomics (2012) 1.14
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Fat caves: caveolae, lipid trafficking and lipid metabolism in adipocytes. Trends Endocrinol Metab (2011) 1.09
Hepatitis C virus utilizes lipid droplet for production of infectious virus. Proc Jpn Acad Ser B Phys Biol Sci (2009) 1.09
Ancient ubiquitous protein 1 (AUP1) localizes to lipid droplets and binds the E2 ubiquitin conjugase G2 (Ube2g2) via its G2 binding region. J Biol Chem (2010) 1.09
Identification of the major functional proteins of prokaryotic lipid droplets. J Lipid Res (2011) 1.07
Isolating lipid droplets from multiple species. Nat Protoc (2012) 1.06
Rab proteins implicated in lipid storage and mobilization. J Biomed Res (2014) 1.05
Mitochondrial and cellular mechanisms for managing lipid excess. Front Physiol (2014) 1.00
Identification of a new class of lipid droplet-associated proteins in plants. Plant Physiol (2013) 1.00
Postlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes. Mol Biol Cell (2012) 0.98
Characterisation of the dynamic behaviour of lipid droplets in the early mouse embryo using adaptive harmonic generation microscopy. BMC Cell Biol (2010) 0.97
Role for ADP ribosylation factor 1 in the regulation of hepatitis C virus replication. J Virol (2010) 0.97
Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction. Am J Physiol Regul Integr Comp Physiol (2013) 0.97
Ablation of vimentin results in defective steroidogenesis. Endocrinology (2012) 0.96
Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. Lipids Health Dis (2010) 0.96
Interaction between the triglyceride lipase ATGL and the Arf1 activator GBF1. PLoS One (2011) 0.95
Coordination of storage lipid synthesis and membrane biogenesis: evidence for cross-talk between triacylglycerol metabolism and phosphatidylinositol synthesis. J Biol Chem (2010) 0.95
Identification of the lipid droplet targeting domain of the Cidea protein. J Lipid Res (2010) 0.92
Label-free imaging of lipid-droplet intracellular motion in early Drosophila embryos using femtosecond-stimulated Raman loss microscopy. Biophys J (2012) 0.92
The emergence of lipid droplets in yeast: current status and experimental approaches. Curr Genet (2013) 0.90
Cholesterol depletion in adipocytes causes caveolae collapse concomitant with proteosomal degradation of cavin-2 in a switch-like fashion. PLoS One (2012) 0.89
Microalgal lipid droplets: composition, diversity, biogenesis and functions. Plant Cell Rep (2014) 0.88
Metabolic switching of human myotubes is improved by n-3 fatty acids. J Lipid Res (2010) 0.88
Accumulation of high-value lipids in single-cell microorganisms: a mechanistic approach and future perspectives. J Agric Food Chem (2014) 0.86
An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER. Cell Rep (2013) 0.85
Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology. J Neuroinflammation (2015) 0.84
YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis. Mol Biol Cell (2011) 0.84
SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells. Mol Endocrinol (2016) 0.83
Calcium-dependent physiologic and pathologic stimulus-metabolic response coupling in hepatocytes. Cell Calcium (2012) 0.83
C13C4.5/Spinster, an evolutionarily conserved protein that regulates fertility in C. elegans through a lysosome-mediated lipid metabolism process. Protein Cell (2013) 0.83
Endoplasmic Reticulum: The Favorite Intracellular Niche for Viral Replication and Assembly. Viruses (2016) 0.81
Glucagon regulates intracellular distribution of adipose differentiation-related protein during triacylglycerol accumulation in the liver. J Lipid Res (2010) 0.81
Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism. Alcohol Clin Exp Res (2013) 0.81
Lipid Droplets as Signaling Platforms Linking Metabolic and Cellular Functions. Lipid Insights (2014) 0.81
Mast cells: from lipid droplets to lipid mediators. Clin Sci (Lond) (2013) 0.80
Developmental changes in the protein composition of Manduca sexta lipid droplets. Insect Biochem Mol Biol (2012) 0.80
Novel flow cytometric approach for the detection of adipocyte subpopulations during adipogenesis. J Lipid Res (2016) 0.79
Milk lipid secretion: recent biomolecular aspects. Biomol Concepts (2012) 0.78
Use of fluorescence microscopy to probe intracellular lipolysis. Methods Enzymol (2014) 0.78
Molecular speciation and dynamics of oxidized triacylglycerols in lipid droplets: Mass spectrometry and coarse-grained simulations. Free Radic Biol Med (2014) 0.78
Lipids to the top of hair biology. J Invest Dermatol (2010) 0.78
Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb. Physiol Rep (2014) 0.77
Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function. J Bioenerg Biomembr (2014) 0.77
Endoplasmic Reticulum Lipid Flux Influences Enterocyte Nuclear Morphology and Lipid-dependent Transcriptional Responses. J Biol Chem (2016) 0.77
The Role of Lipid Droplets in Mortierella alpina Aging Revealed by Integrative Subcellular and Whole-Cell Proteome Analysis. Sci Rep (2017) 0.76
Regulation of lipid droplet dynamics in Saccharomyces cerevisiae depends on the Rab7-like Ypt7p, HOPS complex and V1-ATPase. Biol Open (2015) 0.76
Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function. Mol Biol Cell (2014) 0.76
Triglyceride Mobilization from Lipid Droplets Sustains the Anti-Steatotic Action of Iodothyronines in Cultured Rat Hepatocytes. Front Physiol (2016) 0.75
Importance of endocytic pathways in liver function and disease. Compr Physiol (2014) 0.75
Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes. J Alzheimers Dis (2016) 0.75
SNAREs and cholesterol movement for steroidogenesis. Mol Cell Endocrinol (2016) 0.75
Proteomic analysis of lipid body from the alkenone-producing marine haptophyte alga Tisochrysis lutea. Proteomics (2015) 0.75
Role of n-3 Polyunsaturated Fatty Acids in Ameliorating the Obesity-Induced Metabolic Syndrome in Animal Models and Humans. Int J Mol Sci (2016) 0.75
Lipid droplets form complexes with viroplasms and are crucial for rotavirus replication. Curr Opin Virol (2016) 0.75
Two-photon AIE bio-probe with large Stokes shift for specific imaging of lipid droplets. Chem Sci (2017) 0.75
The structural organization of seed oil bodies could explain the contrasted oil extractability observed in two rapeseed genotypes. Planta (2015) 0.75
CDCP1 drives triple-negative breast cancer metastasis through reduction of lipid-droplet abundance and stimulation of fatty acid oxidation. Proc Natl Acad Sci U S A (2017) 0.75
The Role of Lipid Bodies in the Microglial Aging Process and Related Diseases. Neurochem Res (2017) 0.75
The slim, the fat, and the obese: guess who lives the longest? Curr Genet (2016) 0.75
Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol (2006) 6.85
Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol (2003) 5.45
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell (2008) 4.42
Role of LBPA and Alix in multivesicular liposome formation and endosome organization. Science (2004) 4.35
GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway. Dev Cell (2002) 4.28
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell (2004) 3.95
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction. Nat Cell Biol (2007) 3.90
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc Natl Acad Sci U S A (2005) 3.78
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Endosome-to-cytosol transport of viral nucleocapsids. Nat Cell Biol (2005) 2.98
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol (2008) 2.85
Caveolin-1 is essential for liver regeneration. Science (2006) 2.77
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles. J Cell Biol (2005) 2.74
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell (2010) 2.67
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms. PLoS Biol (2004) 2.59
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway. J Cell Biol (2004) 2.31
Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. Mol Cell Biol (2005) 2.24
Differential sorting and fate of endocytosed GPI-anchored proteins. EMBO J (2002) 2.15
Ras plasma membrane signalling platforms. Biochem J (2005) 2.15
Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism. J Biol Chem (2005) 2.15
Cholesterol manipulation by West Nile virus perturbs the cellular immune response. Cell Host Microbe (2007) 2.14
Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. Mol Cell Biol (2004) 2.09
Not just fat: the structure and function of the lipid droplet. Cold Spring Harb Perspect Biol (2011) 2.07
A novel switch region regulates H-ras membrane orientation and signal output. EMBO J (2008) 2.06
Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin. J Biol Chem (2003) 2.05
Flotillins and the PHB domain protein family: rafts, worms and anaesthetics. Traffic (2005) 2.01
GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif. Mol Biol Cell (2003) 1.93
Rab23, a negative regulator of hedgehog signaling, localizes to the plasma membrane and the endocytic pathway. Traffic (2003) 1.88
Association of stomatin with lipid bodies. J Biol Chem (2004) 1.88
MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J Cell Biol (2009) 1.87
Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta (2005) 1.87
Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol. Mol Biol Cell (2004) 1.86
Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies. Mol Biol Cell (2005) 1.86
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol (2008) 1.85
Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. EMBO J (2003) 1.85
N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein. J Biol Chem (2001) 1.84
Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. J Cell Biol (2010) 1.84
Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites. J Cell Biol (2011) 1.84
Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta (2005) 1.83
Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Mol Cell Biol (2006) 1.81
Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis. Curr Opin Cell Biol (2010) 1.70
A role for phosphatidic acid in the formation of "supersized" lipid droplets. PLoS Genet (2011) 1.69
Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contacts. J Cell Sci (2006) 1.68
Annexin A2-dependent polymerization of actin mediates endosome biogenesis. Dev Cell (2009) 1.67
Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity. Curr Biol (2013) 1.66
Lysobisphosphatidic acid controls endosomal cholesterol levels. J Biol Chem (2008) 1.62
The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway. Curr Biol (2008) 1.62
Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant. Mol Biol Cell (2003) 1.62
Cholesterol-sensitive Cdc42 activation regulates actin polymerization for endocytosis via the GEEC pathway. Traffic (2007) 1.55
Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection. Mol Biol Cell (2002) 1.53
Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation. J Biol Chem (2002) 1.51
Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell. Diabetologia (2013) 1.51
Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking. PLoS One (2007) 1.50
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol (2011) 1.49
A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J Cell Biol (2011) 1.48
A single method for cryofixation and correlative light, electron microscopy and tomography of zebrafish embryos. Traffic (2008) 1.48
Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis. Traffic (2006) 1.48
Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites. J Cell Biol (2014) 1.45
Caveolin, cholesterol, and lipid bodies. Semin Cell Dev Biol (2005) 1.41
Caveolin regulates endocytosis of the muscle repair protein, dysferlin. J Biol Chem (2007) 1.37
GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus. Mol Biol Cell (2002) 1.36
Electrostatic interactions positively regulate K-Ras nanocluster formation and function. Mol Cell Biol (2008) 1.34
Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning. Hum Mol Genet (2005) 1.34
High-resolution 3D quantitative analysis of caveolar ultrastructure and caveola-cytoskeleton interactions. Traffic (2008) 1.32
Observing cell surface signaling domains using electron microscopy. Sci STKE (2003) 1.32
Caveolae at a glance. J Cell Sci (2010) 1.31
Pore-forming toxins induce multiple cellular responses promoting survival. Cell Microbiol (2011) 1.28
A novel hook-related protein family and the characterization of hook-related protein 1. Traffic (2005) 1.27
Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism. J Biol Chem (2011) 1.27
Activation of the MAPK module from different spatial locations generates distinct system outputs. Mol Biol Cell (2008) 1.25
Evolutionary analysis and molecular dissection of caveola biogenesis. J Cell Sci (2008) 1.25
Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation. Mol Cell Biol (2010) 1.25
Visualisation of macropinosome maturation by the recruitment of sorting nexins. J Cell Sci (2006) 1.25
Expression of caveolin-1 enhances cholesterol efflux in hepatic cells. J Biol Chem (2004) 1.24
Hydrophobic and basic domains target proteins to lipid droplets. Traffic (2009) 1.22
Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. J Biol Chem (2003) 1.22
Arf6-independent GPI-anchored protein-enriched early endosomal compartments fuse with sorting endosomes via a Rab5/phosphatidylinositol-3'-kinase-dependent machinery. Mol Biol Cell (2006) 1.21
The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Mol Biol Cell (2011) 1.20
Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens. PLoS One (2010) 1.19
Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J Biol Chem (2013) 1.19
Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo. Hum Mol Genet (2006) 1.19
EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization. Mol Biol Cell (2012) 1.18
RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR. J Biol Chem (2004) 1.17
GLUT4 overexpression or deficiency in adipocytes of transgenic mice alters the composition of GLUT4 vesicles and the subcellular localization of GLUT4 and insulin-responsive aminopeptidase. J Biol Chem (2004) 1.16
Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J Biol Chem (2012) 1.15
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis. Traffic (2013) 1.14
Characterization of Rab18, a lipid droplet-associated small GTPase. Methods Enzymol (2008) 1.14
Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3. Hum Mol Genet (2005) 1.14
Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks. Biochim Biophys Acta (2010) 1.14
Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains. J Cell Biol (2013) 1.11
Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. J Cell Biol (2014) 1.10