Published in Mol Nutr Food Res on November 01, 2008
Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal (2011) 1.57
Radiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposure. Microb Ecol Health Dis (2012) 1.39
Selenium and selenocysteine: roles in cancer, health, and development. Trends Biochem Sci (2014) 1.30
Molecular mechanisms by which selenoproteins affect cancer risk and progression. Biochim Biophys Acta (2009) 1.29
Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein. Carcinogenesis (2010) 1.11
Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development. Molecules (2009) 0.95
Heavy ions, radioprotectors and genomic instability: implications for human space exploration. Radiat Environ Biophys (2009) 0.91
Understanding selenoprotein function and regulation through the use of rodent models. Biochim Biophys Acta (2012) 0.89
Molecular cross-talk between members of distinct families of selenium containing proteins. Mol Nutr Food Res (2013) 0.89
Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications. Physiol Rev (2016) 0.81
Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells. Free Radic Res (2012) 0.80
Distribution and inhibition effect of Seleno-L-Methionine on 4T1 mouse mammary carcinoma. Int J Physiol Pathophysiol Pharmacol (2015) 0.75
Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology--a subgroup analysis of a multicenter, phase III trial. Radiat Oncol (2013) 0.75
Loss of heterozygosity at the glutathione peroxidase 1 locus is not an early event in colon carcinogenesis. Genes Cancer (2011) 0.75
The protective effects of trace elements against side effects induced by ionizing radiation. Radiat Oncol J (2015) 0.75
The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci U S A (2002) 2.91
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice. J Leukoc Biol (2009) 2.38
Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum (2009) 2.23
The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo. Mol Med (2006) 2.11
Histone hyperacetylation is associated with amelioration of experimental colitis in mice. J Immunol (2006) 2.09
Interleukin-18 and host defense against infection. J Infect Dis (2003) 2.04
Leptin: a pivotal mediator of intestinal inflammation in mice. Gastroenterology (2002) 1.96
Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Res (2003) 1.76
Adiponectin deficiency protects mice from chemically induced colonic inflammation. Gastroenterology (2006) 1.32
Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice. Int Immunol (2005) 1.30
Molecular mechanisms by which selenoproteins affect cancer risk and progression. Biochim Biophys Acta (2009) 1.29
Patients with nontuberculous mycobacterial lung disease exhibit unique body and immune phenotypes. Am J Respir Crit Care Med (2012) 1.28
Elevated systemic hepcidin and iron depletion in obese premenopausal females. Obesity (Silver Spring) (2009) 1.28
Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model. Proc Natl Acad Sci U S A (2006) 1.27
Acute leptin deficiency, leptin resistance, and the physiologic response to leptin withdrawal. Proc Natl Acad Sci U S A (2005) 1.17
Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration. J Immunol (2008) 1.17
Retracted Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B. J Biol Chem (2002) 1.15
Molecular consequences of genetic variations in the glutathione peroxidase 1 selenoenzyme. Cancer Res (2009) 1.15
Endogenous interferon-gamma is required for efficient skeletal muscle regeneration. Am J Physiol Cell Physiol (2008) 1.15
Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice. Proc Natl Acad Sci U S A (2008) 1.13
Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein. Carcinogenesis (2010) 1.11
Protective role of resting heart rate on all-cause and cardiovascular disease mortality. Mayo Clin Proc (2013) 1.10
IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc Natl Acad Sci U S A (2003) 1.06
Validation of a novel protocol for calculating estimated energy requirements and average daily physical activity ratio for the US population: 2005-2006. Mayo Clin Proc (2013) 1.05
Mesenchymal stem cells in models of acute pancreatitis. Gastroenterology (2013) 1.04
Role and regulation of adipokines during zymosan-induced peritoneal inflammation in mice. Endocrinology (2008) 1.04
Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1. Infect Immun (2002) 1.04
Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice. PLoS One (2013) 1.04
Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease. Am J Physiol Gastrointest Liver Physiol (2010) 1.03
Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth. J Nutr (2003) 1.03
Leptin deficiency, not obesity, protects mice from Con A-induced hepatitis. Eur J Immunol (2002) 1.03
Selenium and GPx-1 overexpression protect mammalian cells against UV-induced DNA damage. Biol Trace Elem Res (2007) 1.03
Role of leptin deficiency in early acute renal failure during endotoxemia in ob/ob mice. J Am Soc Nephrol (2004) 1.02
Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology (2005) 1.01
Inverse association between glutathione peroxidase activity and both selenium-binding protein 1 levels and Gleason score in human prostate tissue. Prostate (2011) 1.00
Manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by the free thiol form of amifostine and tumor necrosis factor alpha. Radiat Res (2007) 1.00
Role of leptin receptor-induced STAT3 signaling in modulation of intestinal and hepatic inflammation in mice. J Leukoc Biol (2008) 1.00
The link between selenium and chemoprevention: a case for selenoproteins. J Nutr (2004) 0.98
Development of intestinal inflammation in double IL-10- and leptin-deficient mice. J Leukoc Biol (2004) 0.97
Allelic loss of the gene for the GPX1 selenium-containing protein is a common event in cancer. J Nutr (2005) 0.97
Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors. PLoS One (2010) 0.96
Effect of interleukin-18 on mouse core body temperature. Am J Physiol Regul Integr Comp Physiol (2002) 0.95
Decreased serum hepcidin and improved functional iron status 6 months after restrictive bariatric surgery. Obesity (Silver Spring) (2010) 0.95
GPx-1 modulates Akt and P70S6K phosphorylation and Gadd45 levels in MCF-7 cells. Free Radic Biol Med (2004) 0.94
Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice. Cytokine (2007) 0.94
Role of interleukin-18 in host defense against disseminated Candida albicans infection. Infect Immun (2002) 0.94
Effect of diet-induced obesity on acute pancreatitis induced by administration of interleukin-12 plus interleukin-18 in mice. Obesity (Silver Spring) (2009) 0.94
A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe). Food Funct (2013) 0.93
Adiponectin deficiency: role in chronic inflammation induced colon cancer. Biochim Biophys Acta (2011) 0.92
Dietary supplements and human health: for better or for worse? Mol Nutr Food Res (2010) 0.92
Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function. Obesity (Silver Spring) (2013) 0.91
Physical activity reduces prostate carcinogenesis in a transgenic model. Prostate (2009) 0.91
A regulatory role for Sec tRNA[Ser]Sec in selenoprotein synthesis. RNA (2004) 0.91
PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity. J Clin Endocrinol Metab (2012) 0.90
Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations. Food Funct (2012) 0.90
Role of IL-6 in the resolution of pancreatitis in obese mice. J Leukoc Biol (2012) 0.90
Molecular cross-talk between members of distinct families of selenium containing proteins. Mol Nutr Food Res (2013) 0.89
Effect of exercise on chemically-induced colitis in adiponectin deficient mice. J Inflamm (Lond) (2012) 0.88
Hematological and acute-phase responses to diet-induced obesity in IL-6 KO mice. Cytokine (2011) 0.88
Single-dose pharmacokinetic study of lycopene delivered in a well-defined food-based lycopene delivery system (tomato paste-oil mixture) in healthy adult male subjects. Cancer Epidemiol Biomarkers Prev (2004) 0.88
Nonalcoholic fatty liver disease in severely obese adolescent and adult patients. Obesity (Silver Spring) (2013) 0.88
Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women's Health Initiative Observational Study and meta-analysis. Cancer Epidemiol Biomarkers Prev (2011) 0.88
Homocysteine suppresses lipolysis in adipocytes by activating the AMPK pathway. Am J Physiol Endocrinol Metab (2011) 0.88
GM-CSF DNA induces specific patterns of cytokines and chemokines in the skin: implications for DNA vaccines. Cytokines Cell Mol Ther (2002) 0.87
Fatigue, inflammation, and projected mortality in heart failure. J Card Fail (2012) 0.87
Adiponectin deficiency does not affect the inflammatory response to endotoxin or concanavalin a in mice. Endocrinology (2006) 0.86
Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice. Shock (2006) 0.86
Generation of leptin receptor bone marrow chimeras: recovery from irradiation, immune cellularity, cytokine expression, and metabolic parameters. Obesity (Silver Spring) (2010) 0.86
Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer. Int J Colorectal Dis (2013) 0.85
Allelic loss at the GPx-1 locus in cancer of the head and neck. Biol Trace Elem Res (2004) 0.85
Human immunodeficiency virus type 1 gag-specific mucosal immunity after oral immunization with papillomavirus pseudoviruses encoding gag. J Virol (2004) 0.85
New pathways to control inflammatory responses in adipose tissue. Curr Opin Pharmacol (2013) 0.85
Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF. Cytokine (2003) 0.84
Induction of mucosal and systemic immune responses against human carcinoembryonic antigen by an oral vaccine. Cancer Res (2005) 0.83
Induction of thymocyte apoptosis by systemic administration of concanavalin A in mice: role of TNF-alpha, IFN-gamma and glucocorticoids. Eur J Immunol (2005) 0.83
Adiponectin deficiency does not affect development and progression of spontaneous colitis in IL-10 knockout mice. Am J Physiol Gastrointest Liver Physiol (2008) 0.83
Genetic and functional analysis of mammalian Sep15 selenoprotein. Methods Enzymol (2002) 0.83
Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein. Eur J Immunol (2004) 0.82
Does a role for selenium in DNA damage repair explain apparent controversies in its use in chemoprevention? Mutagenesis (2012) 0.82
The role of adipose tissue-associated macrophages and T lymphocytes in the pathogenesis of inflammatory bowel disease. Cytokine (2012) 0.82
Adiponectin deficiency modulates adhesion molecules expression and cytokine production but does not affect disease severity in the transfer model of colitis. Cytokine (2009) 0.81
Selenium-binding protein 1 as a tumor suppressor and a prognostic indicator of clinical outcome. Biomark Res (2013) 0.81
Rosiglitazone improves survival and hastens recovery from pancreatic inflammation in obese mice. PLoS One (2012) 0.81
The emerging role of leptin antagonist as potential therapeutic option for inflammatory bowel disease. Int Rev Immunol (2013) 0.81
Cachectic skeletal muscle response to a novel bout of low-frequency stimulation. J Appl Physiol (1985) (2014) 0.81
Enhanced discrimination of single nucleotide polymorphism in genotyping by phosphorothioate proofreading allele-specific amplification. Anal Biochem (2007) 0.81
Obesity and IL-6 interact in modulating the response to endotoxemia in mice. Cytokine (2012) 0.81
Increased adiposity in annexin A1-deficient mice. PLoS One (2013) 0.80
Turning on/off tumor-specific CTL response during progressive tumor growth. J Immunol (2005) 0.80
Leptin antagonist ameliorates chronic colitis in IL-10⁻/⁻ mice. Immunobiology (2013) 0.80
Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells. Free Radic Res (2012) 0.80
Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock. J Infect Dis (2005) 0.80