Published in Trends Biochem Sci on January 28, 2014
Is the inverse association between selenium and bladder cancer due to confounding by smoking? Am J Epidemiol (2015) 1.39
Selenium for preventing cancer. Cochrane Database Syst Rev (2014) 1.17
Biosynthesis of selenium nanoparticles by Azoarcus sp. CIB. Microb Cell Fact (2016) 0.93
Biofortification and phytoremediation of selenium in China. Front Plant Sci (2015) 0.88
Ecology and biotechnology of selenium-respiring bacteria. Microbiol Mol Biol Rev (2015) 0.86
Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine. PLoS One (2015) 0.85
Controlling translation via modulation of tRNA levels. Wiley Interdiscip Rev RNA (2015) 0.83
Redox active motifs in selenoproteins. Proc Natl Acad Sci U S A (2014) 0.83
Therapeutic Effectiveness of Anticancer Phytochemicals on Cancer Stem Cells. Toxins (Basel) (2016) 0.82
Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications. Physiol Rev (2016) 0.81
Exploring the importance of sulfate transporters and ATP sulphurylases for selenium hyperaccumulation-a comparison of Stanleya pinnata and Brassica juncea (Brassicaceae). Front Plant Sci (2015) 0.81
Selenoprotein K form an intermolecular diselenide bond with unusually high redox potential. FEBS Lett (2014) 0.80
Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues. Bioconjug Chem (2015) 0.80
Cancer chemoprevention research with selenium in the post-SELECT era: Promises and challenges. Nutr Cancer (2015) 0.79
Effects of selenium biofortification on crop nutritional quality. Front Plant Sci (2015) 0.78
Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility. J Biol Chem (2015) 0.78
(77)Se chemical shift tensor of L-selenocystine: experimental NMR measurements and quantum chemical investigations of structural effects. J Phys Chem B (2015) 0.78
DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: a short-term supplementation trial with respect to GPX1 and SEPP1 polymorphism. Eur J Nutr (2015) 0.77
The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways. PLoS One (2015) 0.76
Nanocrystalline hydroxyapatite enriched in selenite and manganese ions: physicochemical and antibacterial properties. Nanoscale Res Lett (2015) 0.76
Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy. Cancers (Basel) (2015) 0.76
Redox Pioneer: Professor Vadim N. Gladyshev. Antioxid Redox Signal (2016) 0.76
Roles of selenoprotein antioxidant protection in zebrafish, Danio rerio, subjected to dietary oxidative stress. Fish Physiol Biochem (2015) 0.76
Mitochondrial ROS control of cancer. Semin Cancer Biol (2017) 0.75
An Overview of Selenium Uptake, Metabolism, and Toxicity in Plants. Front Plant Sci (2017) 0.75
The direct role of selenocysteine in [NiFeSe] hydrogenase maturation and catalysis. Nat Chem Biol (2017) 0.75
Update on Lysinuric Protein Intolerance, a Multi-faceted Disease Retrospective cohort analysis from birth to adulthood. Orphanet J Rare Dis (2017) 0.75
Lipid peroxidation and glutathione peroxidase activity relationship in breast cancer depends on functional polymorphism of GPX1. BMC Cancer (2015) 0.75
Selenium in pig nutrition and reproduction: boars and semen quality-a review. Asian-Australas J Anim Sci (2015) 0.75
Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae. Sci Rep (2017) 0.75
Sodium selenate regulates the brain ionome in a transgenic mouse model of Alzheimer's disease. Sci Rep (2016) 0.75
Retracted Glutathione peroxidase's reaction intermediate selenenic acid is stabilized by the protein microenvironment. Free Radic Biol Med (2014) 0.75
The Effect of Selenium Supplementation on Glucose Homeostasis and the Expression of Genes Related to Glucose Metabolism. Nutrients (2016) 0.75
Indications of Selenium Protection against Cadmium and Lead Toxicity in Oilseed Rape (Brassica napus L.). Front Plant Sci (2016) 0.75
Addition of Selenium Improves Immunomodulative Effects of Glucan. N Am J Med Sci (2016) 0.75
Synthesis and characterization of Se-adenosyl-L-selenohomocysteine selenoxide. J Sulphur Chem (2015) 0.75
The Level of Selenium and Oxidative Stress in Workers Chronically Exposed to Lead. Biol Trace Elem Res (2015) 0.75
Selenoprotein T Exerts an Essential Oxidoreductase Activity That Protects Dopaminergic Neurons in Mouse Models of Parkinson's Disease. Antioxid Redox Signal (2016) 0.75
Vegetarianism and colorectal cancer risk in a low-selenium environment: effect modification by selenium status? A possible factor contributing to the null results in British vegetarians. Eur J Nutr (2017) 0.75
Associations between Red Meat Intakes and the Micronutrient Intake and Status of UK Females: A Secondary Analysis of the UK National Diet and Nutrition Survey. Nutrients (2017) 0.75
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2008) 13.35
Characterization of mammalian selenoproteomes. Science (2003) 9.07
The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the 'termination' codon, TGA. EMBO J (1986) 5.94
Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region. Nature (1991) 4.63
Nucleotide sequence and expression of the selenocysteine-containing polypeptide of formate dehydrogenase (formate-hydrogen-lyase-linked) from Escherichia coli. Proc Natl Acad Sci U S A (1986) 4.07
Selenocysteine: the 21st amino acid. Mol Microbiol (1991) 3.48
Biosynthesis of selenocysteine on its tRNA in eukaryotes. PLoS Biol (2007) 2.96
Ribosomal protein L30 is a component of the UGA-selenocysteine recoding machinery in eukaryotes. Nat Struct Mol Biol (2005) 2.55
Chemical characterization of the selenoprotein component of clostridial glycine reductase: identification of selenocysteine as the organoselenium moiety. Proc Natl Acad Sci U S A (1976) 2.43
Focus on mammalian thioredoxin reductases--important selenoproteins with versatile functions. Biochim Biophys Acta (2009) 2.41
RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea. Proc Natl Acad Sci U S A (2006) 2.34
Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Proc Natl Acad Sci U S A (2002) 2.33
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. Biochem J (2003) 2.30
Deletion of selenoprotein P alters distribution of selenium in the mouse. J Biol Chem (2003) 2.27
Glutathione peroxidase: a selenoenzyme. FEBS Lett (1973) 2.13
Thioredoxin and thioredoxin reductase: current research with special reference to human disease. Biochem Biophys Res Commun (2010) 2.09
Eukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporation. Mol Cell (2009) 2.02
Selenocysteine incorporation machinery and the role of selenoproteins in development and health. Prog Nucleic Acid Res Mol Biol (2006) 1.89
Selenoprotein P-expression, functions, and roles in mammals. Biochim Biophys Acta (2009) 1.83
Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells. J Biol Chem (2006) 1.81
MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Mol Cell (2013) 1.77
Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function. J Biol Chem (2003) 1.66
Selective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA. Mol Cell Biol (2001) 1.66
On the potential of thioredoxin reductase inhibitors for cancer therapy. Semin Cancer Biol (2006) 1.63
Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism? Proc Natl Acad Sci U S A (1996) 1.63
Eukaryotic selenoproteins and selenoproteomes. Biochim Biophys Acta (2009) 1.59
The human selenoproteome: recent insights into functions and regulation. Cell Mol Life Sci (2009) 1.50
Selective rescue of selenoprotein expression in mice lacking a highly specialized methyl group in selenocysteine tRNA. J Biol Chem (2004) 1.49
Structure-expression relationships of the 15-kDa selenoprotein gene. Possible role of the protein in cancer etiology. J Biol Chem (2000) 1.45
Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression. J Nutr (2006) 1.43
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration. FASEB J (2009) 1.41
Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply. Biochem J (2005) 1.36
Distribution and functional consequences of nucleotide polymorphisms in the 3'-untranslated region of the human Sep15 gene. Cancer Res (2001) 1.35
Evolutionarily different RNA motifs and RNA-protein complexes to achieve selenoprotein synthesis. Biochimie (2002) 1.33
Lung cancer risk associated with selenium status is modified in smoking individuals by Sep15 polymorphism. Eur J Nutr (2008) 1.33
The Sep15 protein family: roles in disulfide bond formation and quality control in the endoplasmic reticulum. IUBMB Life (2007) 1.30
Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model. Proc Natl Acad Sci U S A (2006) 1.27
A new human selenium-containing protein. Purification, characterization, and cDNA sequence. J Biol Chem (1998) 1.24
Evolution of selenium utilization traits. Genome Biol (2005) 1.22
Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice. Biochem J (2008) 1.16
The Outcome of Selenium and Vitamin E Cancer Prevention Trial (SELECT) reveals the need for better understanding of selenium biology. Mol Interv (2009) 1.16
Selenocysteine in thiol/disulfide-like exchange reactions. Antioxid Redox Signal (2012) 1.13
Selective restoration of the selenoprotein population in a mouse hepatocyte selenoproteinless background with different mutant selenocysteine tRNAs lacking Um34. J Biol Chem (2007) 1.11
Growth inhibition and induction of apoptosis in mesothelioma cells by selenium and dependence on selenoprotein SEP15 genotype. Oncogene (2004) 1.11
Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells. Cancer Prev Res (Phila) (2010) 1.10
Selenoproteins mediate T cell immunity through an antioxidant mechanism. J Biol Chem (2008) 1.07
Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck disease. PLoS Genet (2009) 1.07
Translational redefinition of UGA codons is regulated by selenium availability. J Biol Chem (2013) 1.05
Selenium and vitamin E supplementation for cancer prevention. JAMA (2009) 1.04
Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth. J Nutr (2003) 1.03
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery. Proc Natl Acad Sci U S A (2010) 1.03
Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression. BMC Immunol (2009) 1.03
Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression. Nucleic Acids Res (2010) 1.03
Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice. J Biol Chem (2011) 1.01
Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis. Carcinogenesis (2012) 0.98
Activation of the glutathione peroxidase 2 (GPx2) promoter by beta-catenin. Biol Chem (2007) 0.95
Selenoprotein deficiency enhances radiation-induced micronuclei formation. Mol Nutr Food Res (2008) 0.92
Factor 3 activity of selenium compounds. J Biol Chem (1958) 0.91
Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. Carcinogenesis (2011) 0.90
Post-transcriptional control of selenoprotein biosynthesis. Curr Protein Pept Sci (2012) 0.89
Deficiency in the 15 kDa selenoprotein inhibits human colon cancer cell growth. Nutrients (2011) 0.88
Selenoproteins are essential for proper keratinocyte function and skin development. PLoS One (2010) 0.88
Comparative genomics of trace element dependence in biology. J Biol Chem (2011) 0.88
The yin and yang of nrf2-regulated selenoproteins in carcinogenesis. Int J Cell Biol (2012) 0.88
The selenoproteins GPx2, TrxR2 and TrxR3 are regulated by Wnt signalling in the intestinal epithelium. Biochim Biophys Acta (2012) 0.88
Selenoprotein expression is essential in endothelial cell development and cardiac muscle function. Neuromuscul Disord (2006) 0.87
Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice. PLoS One (2012) 0.87
Selenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis. Carcinogenesis (2012) 0.86
Unveiling the molecular mechanisms behind selenium-related diseases through knockout mouse studies. Antioxid Redox Signal (2010) 0.84
Recent advances in the development of thioredoxin reductase inhibitors as anticancer agents. Curr Drug Targets (2012) 0.84
Thyroid function is maintained despite increased oxidative stress in mice lacking selenoprotein biosynthesis in thyroid epithelial cells. Antioxid Redox Signal (2012) 0.83
Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism. Biochem J (2012) 0.83
Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFα. PLoS One (2013) 0.81
Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis. Carcinogenesis (2013) 0.81
The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens. ISME J (2013) 0.81
High rates of serum selenium deficiency among HIV- and HCV-infected and uninfected drug users in Buenos Aires, Argentina. Public Health Nutr (2011) 0.79
Molecular expression analysis of beta-naphthoflavone-induced hepatocellular tumors in rats. Toxicol Pathol (2009) 0.78
Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development. PLoS One (2013) 0.78
Prostate epithelium-specific deletion of the selenocysteine tRNA gene Trsp leads to early onset intraepithelial neoplasia. Am J Pathol (2014) 0.77
The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal. Aging (Albany NY) (2014) 0.81
Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway. Biochem Biophys Res Commun (2014) 0.80
DNA repair in species with extreme lifespan differences. Aging (Albany NY) (2015) 0.79
Selenium utilization in thioredoxin and catalytic advantage provided by selenocysteine. Biochem Biophys Res Commun (2015) 0.77
Convergent evolution of marine mammals is associated with distinct substitutions in common genes. Sci Rep (2015) 0.77
Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan. Aging (Albany NY) (2016) 0.75
Age-associated molecular changes are deleterious and may modulate life span through diet. Sci Adv (2017) 0.75
Selenoprotein MsrB1 deficiency exacerbates acetaminophen-induced hepatotoxicity via increased oxidative damage. Arch Biochem Biophys (2017) 0.75