Published in Am J Cardiol on June 26, 2008
Cellular and molecular mechanisms of thoracic aortic aneurysms. Nat Rev Cardiol (2009) 1.65
Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves. J Clin Invest (2010) 1.51
Clinical utility gene card for: Loeys-Dietz syndrome (TGFBR1/2) and related phenotypes. Eur J Hum Genet (2011) 1.07
Identification of fibrillin 1 gene mutations in patients with bicuspid aortic valve (BAV) without Marfan syndrome. BMC Med Genet (2014) 0.98
Congenital heart malformations induced by hemodynamic altering surgical interventions. Front Physiol (2014) 0.97
The genetic and molecular basis of bicuspid aortic valve associated thoracic aortopathy: a link to phenotype heterogeneity. Ann Cardiothorac Surg (2013) 0.97
Sequencing of NOTCH1, GATA5, TGFBR1 and TGFBR2 genes in familial cases of bicuspid aortic valve. BMC Med Genet (2013) 0.93
A family-based paradigm to identify candidate chromosomal regions for isolated congenital diaphragmatic hernia. Am J Med Genet A (2012) 0.91
Comprehensive mutation scanning of LMNA in 268 patients with lone atrial fibrillation. Am J Cardiol (2009) 0.82
Shared Segment Analysis and Next-Generation Sequencing Implicates the Retinoic Acid Signaling Pathway in Total Anomalous Pulmonary Venous Return (TAPVR). PLoS One (2015) 0.78
Exome analysis of a family with Wolff-Parkinson-White syndrome identifies a novel disease locus. Am J Med Genet A (2015) 0.76
Bicuspid Aortic Valve: a Review with Recommendations for Genetic Counseling. J Genet Couns (2016) 0.75
Dilatation and Dysfunction of the Neo-aortic Root and in 76 Patients After the Ross Procedure. Pediatr Cardiol (2016) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet (2006) 9.56
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Atenolol versus losartan in children and young adults with Marfan's syndrome. N Engl J Med (2014) 5.11
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Clinical characterization of left ventricular noncompaction in children: a relatively common form of cardiomyopathy. Circulation (2003) 3.54
A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. PLoS Genet (2008) 3.25
Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction. J Am Coll Cardiol (2003) 3.20
Late gadolinium enhancement: precursor to cardiomyopathy in Duchenne muscular dystrophy? Int J Cardiovasc Imaging (2008) 2.96
Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ Res (2006) 2.95
Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome. J Allergy Clin Immunol (2008) 2.50
Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. Mol Genet Metab (2003) 2.42
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome. Hum Mol Genet (2002) 2.16
A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet syndrome. PLoS Genet (2009) 2.12
Molecular remodelling of dystrophin in patients with end-stage cardiomyopathies and reversal in patients on assistance-device therapy. Lancet (2002) 2.06
KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions: expansion of the functional and mutation spectrum. Brain (2003) 1.92
Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosis. J Am Coll Cardiol (2010) 1.88
Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells. Blood (2010) 1.88
Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. Nicotine Tob Res (2009) 1.84
Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with albuminuria in hypertensive African Americans: the HyperGEN study. Am J Nephrol (2009) 1.80
Genome scans for blood pressure and hypertension: the National Heart, Lung, and Blood Institute Family Heart Study. Hypertension (2002) 1.66
Neuropathy target esterase gene mutations cause motor neuron disease. Am J Hum Genet (2008) 1.66
Role of activating FcγR gene polymorphisms in Kawasaki disease susceptibility and intravenous immunoglobulin response. Circ Cardiovasc Genet (2012) 1.65
Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy. Mol Genet Metab (2007) 1.60
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet (2013) 1.57
Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury. Am J Physiol Heart Circ Physiol (2006) 1.50
The immediate and long-term impact of pregnancy on aortic growth rate and mortality in women with Marfan syndrome. J Am Coll Cardiol (2012) 1.47
Prognostic significance of p53 mutations in colon cancer at the population level. Int J Cancer (2002) 1.46
AGT genetic variation, plasma AGT, and blood pressure: An analysis of the Utah Genetic Reference Project pedigrees. Am J Hypertens (2010) 1.43
Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: toxicity, clinical response, and immunological response to minor histocompatibility antigens. Clin Cancer Res (2004) 1.42
Cardiac-specific overexpression of melanoma differentiation-associated gene-5 protects mice from lethal viral myocarditis. Circ Heart Fail (2012) 1.40
Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. J Physiol (2008) 1.35
Genetic analysis in patients with left ventricular noncompaction and evidence for genetic heterogeneity. Mol Genet Metab (2006) 1.33
A cardiac myosin binding protein C mutation in the Maine Coon cat with familial hypertrophic cardiomyopathy. Hum Mol Genet (2005) 1.32
Mutation analysis of the G4.5 gene in patients with isolated left ventricular noncompaction. Mol Genet Metab (2002) 1.28
Associations between phenylthiocarbamide gene polymorphisms and cigarette smoking. Nicotine Tob Res (2005) 1.27
Danon disease as an underrecognized cause of hypertrophic cardiomyopathy in children. Circulation (2005) 1.24
Genetic testing and phenotype in a large kindred with attenuated familial adenomatous polyposis. Gastroenterology (2004) 1.22
ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene. J Am Coll Cardiol (2009) 1.22
Lapse of care as a predictor for morbidity in adults with congenital heart disease. Int J Cardiol (2007) 1.22
A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Respir Crit Care Med (2003) 1.19
Alternating hemiplegia of childhood or familial hemiplegic migraine? A novel ATP1A2 mutation. Ann Neurol (2004) 1.18
Molecular normalization of dystrophin in the failing left and right ventricle of patients treated with either pulsatile or continuous flow-type ventricular assist devices. J Am Coll Cardiol (2004) 1.17
Diviner Lunar Radiometer observations of cold traps in the Moon's south polar region. Science (2010) 1.15
Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis. J Exp Med (2008) 1.14
Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy. Am Heart J (2013) 1.14
A genome-wide affected sibpair linkage analysis of hypertension: the HyperGEN network. Am J Hypertens (2003) 1.12
Further evidence for the role of genes on chromosome 2 and chromosome 5 in the inheritance of pulmonary function. Am J Respir Crit Care Med (2003) 1.12
A role for Toll-like receptor 3 variants in host susceptibility to enteroviral myocarditis and dilated cardiomyopathy. J Biol Chem (2010) 1.11
American founder mutation for attenuated familial adenomatous polyposis. Clin Gastroenterol Hepatol (2007) 1.10
Somatic mosaicism contributes to phenotypic variation in Timothy syndrome. Am J Med Genet A (2011) 1.09
Common variant of human NEDD4L activates a cryptic splice site to form a frameshifted transcript. J Hum Genet (2002) 1.09
Global silicate mineralogy of the Moon from the Diviner lunar radiometer. Science (2010) 1.06
Progression of aortic dilation in children with a functionally normal bicuspid aortic valve. Am J Cardiol (2006) 1.05
Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22. J Invest Dermatol (2008) 1.04
Identification of rare recurrent copy number variants in high-risk autism families and their prevalence in a large ASD population. PLoS One (2013) 1.03
Functional FCGR2B gene variants influence intravenous immunoglobulin response in patients with Kawasaki disease. J Allergy Clin Immunol (2011) 1.03
Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2). Am J Med Genet B Neuropsychiatr Genet (2005) 1.03
Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms. Hum Mol Genet (2010) 0.99
Carriers of rare missense variants in IFIH1 are protected from psoriasis. J Invest Dermatol (2010) 0.97
Haploinsufficiency of the LIM domain containing preferred translocation partner in lipoma (LPP) gene in patients with tetralogy of Fallot and VACTERL association. Am J Med Genet A (2010) 0.97
Relation of maternal anti-Ro/La antibodies to aortic dilation in patients with congenital complete heart block. Am J Cardiol (2011) 0.96
Allelic variants of human melatonin 1A receptor in patients with familial adolescent idiopathic scoliosis. Spine (Phila Pa 1976) (2003) 0.95
Compound heterozygous mutations in KvLQT1 cause Jervell and Lange-Nielsen syndrome. Mol Genet Metab (2002) 0.95
Identification of a novel TPM1 mutation in a family with left ventricular noncompaction and sudden death. Mol Genet Metab (2010) 0.95
Novel mutations in domain I of SCN5A cause Brugada syndrome. Mol Genet Metab (2002) 0.94
Evidence for linkage on chromosome 3q25-27 in a large autism extended pedigree. Hum Hered (2006) 0.94
Further evidence of a quantitative trait locus on chromosome 18 influencing postural change in systolic blood pressure: the Hypertension Genetic Epidemiology Network (HyperGEN) Study. Am J Hypertens (2005) 0.94
Colonic adenoma risk in familial colorectal cancer--a study of six extended kindreds. Am J Gastroenterol (2008) 0.94
Dilated cardiomyopathy: a tale of cytoskeletal proteins and beyond. J Cardiovasc Electrophysiol (2006) 0.94
Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy. Hum Genet (2002) 0.94
Living at an altitude adversely affects exercise capacity in Fontan patients. Cardiol Young (2010) 0.93
Pediatric arteriovenous extracorporeal membrane oxygenation (ECMO) as a bridge to cardiac transplantation. J Heart Lung Transplant (2003) 0.92
Exome analysis of a family with pleiotropic congenital heart disease. Circ Cardiovasc Genet (2012) 0.92
Surgical correction of mitral valve prolapse : a cure for recurrent ventricular tachycardia in Marfan syndrome? Pediatr Cardiol (2006) 0.92
A family-based paradigm to identify candidate chromosomal regions for isolated congenital diaphragmatic hernia. Am J Med Genet A (2012) 0.91
A genome-wide screen reveals evidence for a locus on chromosome 11 influencing variation in LDL cholesterol in the NHLBI Family Heart Study. Hum Genet (2002) 0.91
The 5q31 variants associated with psoriasis and Crohn's disease are distinct. Hum Mol Genet (2008) 0.91
(1)H nuclear magnetic resonance metabolomics analysis identifies novel urinary biomarkers for lung function. J Proteome Res (2010) 0.91
The PHQ-9 as a brief assessment of lifetime major depression. Psychol Assess (2007) 0.90
Isolated left ventricular noncompaction is rarely caused by mutations in G4.5, alpha-dystrobrevin and FK Binding Protein-12. Mol Genet Metab (2004) 0.90
Cardiotropic viruses in the myocardium of children with end-stage heart disease. J Heart Lung Transplant (2004) 0.90
Non-synonymous variants in pre-B cell leukemia homeobox (PBX) genes are associated with congenital heart defects. Eur J Med Genet (2012) 0.89
Population-wide infant screening for HLA-based type 1 diabetes risk via dried blood spots from the public health infrastructure. Ann N Y Acad Sci (2003) 0.88
Accuracy of ECG interpretation in the pediatric emergency department. Ann Emerg Med (2005) 0.88
Cardiovascular surgery in children with Marfan syndrome or Loeys-Dietz syndrome. J Thorac Cardiovasc Surg (2009) 0.87
Distal aortic and peripheral arterial aneurysms in patients with Marfan syndrome. J Am Coll Cardiol (2011) 0.87
Mitral valve replacement in children: predictors of long-term outcome. Ann Thorac Surg (2003) 0.86
Gonadal mosaicism of a TAZ (G4.5) mutation in a Japanese family with Barth syndrome and left ventricular noncompaction. Mol Genet Metab (2010) 0.86
Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions. Epilepsia (2009) 0.85
Viral epidemiologic shift in inflammatory heart disease: the increasing involvement of parvovirus B19 in the myocardium of pediatric cardiac transplant patients. J Heart Lung Transplant (2010) 0.85
Identification and initial characterization of 6,000 expressed sequenced tags (ESTs) from rat normal-growing cartilage and swarm rat chondrosarcoma cDNA libraries. Iowa Orthop J (2002) 0.84
Comparison of the pattern of aortic dilation in children with the Marfan's syndrome versus children with a bicuspid aortic valve. Am J Cardiol (2006) 0.83
Mitral valve avulsion after a four-wheel all-terrain vehicle crash. J Trauma (2004) 0.83
SCN5A variants in Japanese patients with left ventricular noncompaction and arrhythmia. Mol Genet Metab (2008) 0.83
Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer. J Med Genet (2010) 0.83