Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effective antiviral activity.

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Published in J Med Chem on August 01, 1991

Authors

S Thaisrivongs1, A G Tomasselli, J B Moon, J Hui, T J McQuade, S R Turner, J W Strohbach, W J Howe, W G Tarpley, R L Heinrikson

Author Affiliations

1: Department of Medicinal Chemistry, Upjohn Company, Kalamazoo, Michigan 49001.

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