Published in Biochim Biophys Acta on August 08, 2008
NAD+-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10. J Biol Chem (2009) 1.43
Role of an ER stress response element in regulating the bidirectional promoter of the mouse CRELD2 - ALG12 gene pair. BMC Genomics (2010) 0.75
Differential co-expression analysis of venous thromboembolism based on gene expression profile data. Exp Ther Med (2016) 0.75
Characteristics of Antisense Transcript Promoters and the Regulation of Their Activity. Int J Mol Sci (2015) 0.75
Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature (2004) 11.59
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proc Natl Acad Sci U S A (2005) 3.42
Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication. Cell (2002) 2.32
Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand. EMBO J (2006) 1.93
Mammalian mitochondrial DNA replicates bidirectionally from an initiation zone. J Biol Chem (2003) 1.83
No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. PLoS Genet (2007) 1.82
Response: The mitochondrial DNA replication bubble has not burst. Trends Biochem Sci (2003) 1.80
A bidirectional origin of replication maps to the major noncoding region of human mitochondrial DNA. Mol Cell (2005) 1.79
Mitochondrial medicine: a metabolic perspective on the pathology of oxidative phosphorylation disorders. Cell Metab (2006) 1.62
Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells. Nucleic Acids Res (2006) 1.51
Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter. Nat Struct Mol Biol (2011) 1.51
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid. J Mol Biol (2010) 1.50
The mitochondrial transcription termination factor mTERF modulates replication pausing in human mitochondrial DNA. Nucleic Acids Res (2007) 1.38
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction. Proc Natl Acad Sci U S A (2010) 1.37
Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production. J Biol Chem (2010) 1.33
Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab (2009) 1.29
Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila. Aging (Albany NY) (2010) 1.19
Gene expression in a Drosophila model of mitochondrial disease. PLoS One (2010) 1.16
Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat. Nat Struct Mol Biol (2010) 1.12
Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts. Nucleic Acids Res (2013) 1.10
Human heart mitochondrial DNA is organized in complex catenated networks containing abundant four-way junctions and replication forks. J Biol Chem (2009) 1.09
Allotopic expression of a mitochondrial alternative oxidase confers cyanide resistance to human cell respiration. EMBO Rep (2005) 1.06
Expression of the alternative oxidase complements cytochrome c oxidase deficiency in human cells. EMBO Mol Med (2009) 1.05
Systematic segregation to mutant mitochondrial DNA and accompanying loss of mitochondrial DNA in human NT2 teratocarcinoma Cybrids. Genetics (2005) 1.00
The 7472insC mitochondrial DNA mutation impairs the synthesis and extent of aminoacylation of tRNASer(UCN) but not its structure or rate of turnover. J Biol Chem (2002) 1.00
A mitochondrial ribosomal and RNA decay pathway blocks cell proliferation. Curr Biol (2013) 0.99
Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases. FEBS Lett (2005) 0.95
Respiratory chain alternative enzymes as tools to better understand and counteract respiratory chain deficiencies in human cells and animals. Physiol Plant (2009) 0.94
Overexpression of MTERFD1 or MTERFD3 impairs the completion of mitochondrial DNA replication. Mol Biol Rep (2010) 0.92
The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic. Genetics (2008) 0.92
Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproduction. PLoS Genet (2013) 0.91
Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency. Hum Mol Genet (2013) 0.91
A prevalent POLG CAG microsatellite length allele in humans and African great apes. Mamm Genome (2004) 0.89
A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila. Genetics (2012) 0.89
Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila. Hum Mol Genet (2012) 0.89
Developmental and pathological changes in the human cardiac muscle mitochondrial DNA organization, replication and copy number. PLoS One (2010) 0.88
The bidirectional promoter of two genes for the mitochondrial translational apparatus in mouse is regulated by an array of CCAAT boxes interacting with the transcription factor NF-Y. Nucleic Acids Res (2006) 0.87
Glucose modulates respiratory complex I activity in response to acute mitochondrial dysfunction. J Biol Chem (2012) 0.86
The relationship between somatic mtDNA rearrangements, human heart disease and aging. Hum Mol Genet (2002) 0.85
DNA conformation-dependent activities of human mitochondrial RNA polymerase. Genes Cells (2009) 0.85
Engineering the alternative oxidase gene to better understand and counteract mitochondrial defects: state of the art and perspectives. Br J Pharmacol (2014) 0.85
Phenotypic suppression of the Drosophila mitochondrial disease-like mutant tko(25t) by duplication of the mutant gene in its natural chromosomal context. Mitochondrion (2009) 0.85
Gene dosage and selective expression modify phenotype in a Drosophila model of human mitochondrial disease. Mitochondrion (2003) 0.84
Novel repetitive structures, deviant protein-encoding sequences and unidentified ORFs in the mitochondrial genome of the brachiopod Lingula anatina. J Mol Evol (2005) 0.84
Unique features of DNA replication in mitochondria: a functional and evolutionary perspective. Bioessays (2014) 0.84
The alternative oxidase, a tool for compensating cytochrome c oxidase deficiency in human cells. Physiol Plant (2009) 0.83
Effects on mitochondrial transcription of manipulating mTERF protein levels in cultured human HEK293 cells. BMC Mol Biol (2010) 0.83
dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. Cell Cycle (2012) 0.83
Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect. Hum Mol Genet (2006) 0.83
Mitochondrial transcription terminator family members mTTF and mTerf5 have opposing roles in coordination of mtDNA synthesis. PLoS Genet (2013) 0.82
Analysis of replication intermediates indicates that Drosophila melanogaster mitochondrial DNA replicates by a strand-coupled theta mechanism. PLoS One (2013) 0.81
The 7472insC mtDNA mutation impairs 5' and 3' processing of tRNA(Ser(UCN)). Biochem Biophys Res Commun (2004) 0.81
Genome wide study of NF-Y type CCAAT boxes in unidirectional and bidirectional promoters in human and mouse. J Theor Biol (2011) 0.81
NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells. Biochim Biophys Acta (2009) 0.80
Comparative genetics of functional trinucleotide tandem repeats in humans and apes. J Mol Evol (2004) 0.78
Therapies in inborn errors of oxidative metabolism. Trends Endocrinol Metab (2012) 0.78
Correction: Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth. PLoS One (2016) 0.75
On modeling of mutation probabilities. Comput Biol Med (2007) 0.75
The Euromit meetings: an international platform for the understanding and combat of mitochondrial disease. Biochim Biophys Acta (2004) 0.75