Scott H Randell

Author PubWeight™ 114.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci U S A 2009 7.24
2 Well-differentiated human airway epithelial cell cultures. Methods Mol Med 2005 4.66
3 Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene 2002 3.80
4 Lung development and repair: contribution of the ciliated lineage. Proc Natl Acad Sci U S A 2006 3.57
5 Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling. Dis Model Mech 2010 3.17
6 Notch-dependent differentiation of adult airway basal stem cells. Cell Stem Cell 2011 2.95
7 Type 2 alveolar cells are stem cells in adult lung. J Clin Invest 2013 2.93
8 Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem 2009 2.59
9 Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2011 2.42
10 Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types. Clin Cancer Res 2010 2.15
11 Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am J Physiol Cell Physiol 2004 2.04
12 Airway epithelial cells: current concepts and challenges. Proc Am Thorac Soc 2008 1.90
13 Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. J Immunol 2003 1.82
14 A subset of mouse tracheal epithelial basal cells generates large colonies in vitro. Am J Physiol Lung Cell Mol Physiol 2003 1.80
15 Terminal N-linked galactose is the primary receptor for adeno-associated virus 9. J Biol Chem 2011 1.73
16 Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc Natl Acad Sci U S A 2013 1.73
17 Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation. PLoS One 2012 1.72
18 Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury. J Immunol 2006 1.68
19 Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR. PLoS One 2011 1.58
20 Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes. PLoS One 2013 1.52
21 Cystic fibrosis and other respiratory diseases of impaired mucus clearance. Toxicol Pathol 2007 1.46
22 Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells. Proc Natl Acad Sci U S A 2012 1.46
23 Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces. J Immunol 2005 1.38
24 Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures. Am J Physiol Lung Cell Mol Physiol 2009 1.37
25 Cytokine secretion by cystic fibrosis airway epithelial cells. Am J Respir Crit Care Med 2003 1.34
26 Transcellular thiocyanate transport by human airway epithelia. J Physiol 2004 1.30
27 DiffSplice: the genome-wide detection of differential splicing events with RNA-seq. Nucleic Acids Res 2012 1.28
28 Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury. Stem Cells 2012 1.26
29 The lactoperoxidase system links anion transport to host defense in cystic fibrosis. FEBS Lett 2006 1.23
30 Human nasal and tracheo-bronchial respiratory epithelial cell culture. Methods Mol Biol 2013 1.23
31 Mucins and their O-Glycans from human bronchial epithelial cell cultures. Am J Physiol Lung Cell Mol Physiol 2004 1.20
32 Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment. J Immunol 2009 1.17
33 Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema. Am J Physiol Lung Cell Mol Physiol 2009 1.15
34 Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus. Mol Microbiol 2011 1.14
35 Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium. Am J Respir Crit Care Med 2004 1.14
36 Mutations in RSPH1 cause primary ciliary dyskinesia with a unique clinical and ciliary phenotype. Am J Respir Crit Care Med 2014 1.14
37 Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling. J Biol Chem 2010 1.08
38 SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis. Am J Respir Cell Mol Biol 2005 1.08
39 Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy. Proc Natl Acad Sci U S A 2010 1.07
40 β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. J Cell Sci 2012 1.05
41 Airway epithelial cell tolerance to Pseudomonas aeruginosa. Respir Res 2005 1.05
42 Epithelial kinetics in mouse heterotopic tracheal allografts. Am J Transplant 2002 1.04
43 Counteracting signaling activities in lipid rafts associated with the invasion of lung epithelial cells by Pseudomonas aeruginosa. J Biol Chem 2009 1.02
44 C-Mannosylation of MUC5AC and MUC5B Cys subdomains. Glycobiology 2004 1.02
45 Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function. Proc Am Thorac Soc 2008 1.02
46 Potential role of abnormal ion transport in the pathogenesis of chronic sinusitis. Arch Otolaryngol Head Neck Surg 2006 1.01
47 Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]. Proc Natl Acad Sci U S A 2013 1.01
48 Murine epithelial cells: isolation and culture. J Cyst Fibros 2004 0.99
49 Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation. EMBO Rep 2004 0.98
50 Stem cells and repair of lung injuries. Respir Res 2004 0.96
51 Plasma membrane localization is required for RasA-mediated polarized morphogenesis and virulence of Aspergillus fumigatus. Eukaryot Cell 2012 0.94
52 Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death. Am J Respir Crit Care Med 2009 0.94
53 Iron accumulates in the lavage and explanted lungs of cystic fibrosis patients. J Cyst Fibros 2012 0.94
54 Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity. Am J Respir Crit Care Med 2014 0.93
55 VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cells. J Physiol 2011 0.93
56 Human airway epithelial cell culture to identify new respiratory viruses: coronavirus NL63 as a model. J Virol Methods 2008 0.92
57 Hierarchical contributions of allorecognition pathways in chronic lung rejection. Am J Respir Crit Care Med 2002 0.91
58 A biomimetic multicellular model of the airways using primary human cells. Lab Chip 2014 0.90
59 Loss of Cftr function exacerbates the phenotype of Na(+) hyperabsorption in murine airways. Am J Physiol Lung Cell Mol Physiol 2013 0.90
60 Human leukocyte antigen mismatches predispose to the severity of bronchiolitis obliterans syndrome after lung transplantation. Chest 2003 0.89
61 Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium. J Pathol 2011 0.88
62 Identification of dynein heavy chain 7 as an inner arm component of human cilia that is synthesized but not assembled in a case of primary ciliary dyskinesia. J Biol Chem 2002 0.88
63 Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction. Physiol Genomics 2012 0.88
64 Making More MUCS. Am J Respir Cell Mol Biol 2003 0.85
65 Expression of the proapoptotic protein Bax is reduced in bronchial mucous cells of asthmatic subjects. Am J Physiol Lung Cell Mol Physiol 2008 0.85
66 SERCA2 regulates non-CF and CF airway epithelial cell response to ozone. PLoS One 2011 0.84
67 Temporal changes in expression of FoxA1 and Wnt7A in isolated adult human alveolar epithelial cells enhanced by heparin. Anat Rec (Hoboken) 2010 0.83
68 Custom-designed wells and flow chamber for exposing air-liquid interface cultures to wall shear stress. Ann Biomed Eng 2006 0.83
69 Highlights of a workshop to discuss targeting inflammation in cystic fibrosis. J Cyst Fibros 2008 0.82
70 Calcineurin inhibitor effects on growth and phenotype of human airway epithelial cells in vitro. Am J Transplant 2005 0.82
71 Breaking the in vitro alveolar type II cell proliferation barrier while retaining ion transport properties. Am J Respir Cell Mol Biol 2014 0.82
72 Intracellular insulin-like growth factor-1 induces Bcl-2 expression in airway epithelial cells. J Immunol 2012 0.81
73 Cytokine amplification by respiratory syncytial virus infection in human nasal epithelial cells. Laryngoscope 2005 0.81
74 Trends in lung pH and PO2 after circulatory arrest: implications for non-heart-beating donors and cell culture models of lung ischemia-reperfusion injury. J Heart Lung Transplant 2005 0.81
75 Regional differences in rat conjunctival ion transport activities. Am J Physiol Cell Physiol 2012 0.80
76 Equine bronchial epithelial cells differentiate into ciliated and mucus producing cells in vitro. In Vitro Cell Dev Biol Anim 2009 0.79
77 Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells. Cancer Lett 2006 0.79
78 Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease. Am J Respir Crit Care Med 2015 0.79
79 Effect of apical hyperosmotic sodium challenge and amiloride on sodium transport in human bronchial epithelial cells from cystic fibrosis donors. Am J Physiol Cell Physiol 2013 0.79
80 Real-time monitoring of keratin 5 expression during burn re-epithelialization. J Surg Res 2004 0.78
81 Chromosomal abnormalities in bronchial epithelium from smokers, nonsmokers, and lung cancer patients. Cancer Genet Cytogenet 2005 0.77
82 Magnetomotive optical coherence elastography for relating lung structure and function in Cystic Fibrosis. Proc SPIE Int Soc Opt Eng 2010 0.77
83 Expression profiles of aquaporins in rat conjunctiva, cornea, lacrimal gland and Meibomian gland. Exp Eye Res 2012 0.77
84 In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation. J Thorac Cardiovasc Surg 2009 0.75
85 Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways. Am J Respir Cell Mol Biol 2008 0.75
86 An Official American Thoracic Society Workshop Report 2015. Stem Cells and Cell Therapies in Lung Biology and Diseases. Ann Am Thorac Soc 2016 0.75
87 Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med 2016 0.75
88 Airway epithelia. Methods Mol Biol 2003 0.75
89 PX3.102, a novel chinese herb extract, diminishes chronic airway allograft rejection. Transplantation 2004 0.75
90 Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum. Am J Respir Cell Mol Biol 2006 0.75
91 Evaluation of a SPLUNC1-Derived Peptide for the Treatment of Cystic Fibrosis Lung Disease. Am J Physiol Lung Cell Mol Physiol 2017 0.75